Citation Impact
Citing Papers
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Functional Consequences of Neuromyelitis Optica-IgG Astrocyte Interactions on Blood-Brain Barrier Permeability and Granulocyte Recruitment
2008
Effects of Vascular Endothelial Growth Factor on the Lymphocyte-Endothelium Interactions: Identification of Caveolin-1 and Nitric Oxide as Control Points of Endothelial Cell Anergy
2007
Pericytes from Brain Microvessels Strengthen the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells
2007
Multidrug Resistance-Associated Proteins: Expression and Function in the Central Nervous System
2006
Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase
2003
Combination of Hypoxia/Aglycemia Compromises In Vitro Blood-Brain Barrier Integrity
1999
Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts
2004
Neurovascular Unit: a Focus on Pericytes
2012
Astrocyte–endothelial interactions and blood–brain barrier permeability*
2002
Regiospecific Inverse-Electron-Demand Diels–Alder Reaction of Simultaneously Electrogenerated Diene and Dienophile: An Expeditious Route to Polyfunctionalized 1,4-Benzoxazine Derivatives
2002
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Contribution of Carrier-Mediated Transport Systems to the Blood–Brain Barrier as a Supporting and Protecting Interface for the Brain; Importance for CNS Drug Discovery and Development
2007
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact
1999
Strategies to advance translational research into brain barriers
2008
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
2012
Secretion of interleukin‐1β by astrocytes mediates endothelin‐1 and tumour necrosis factor‐α effects on human brain microvascular endothelial cell permeability
2003
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
The Blood-Brain Barrier/Neurovascular Unit in Health and Disease
2005 Standout
Isoform‐Specific Effects of Apolipoproteins E2, E3, and E4 on Cerebral Capillary Sequestration and Blood‐Brain Barrier Transport of Circulating Alzheimer's Amyloid β
1997
Contractile proteins in pericytes at the blood-brain and blood-retinal barriers
2001
Nucleotide signalling during inflammation
2014 StandoutNature
Evolutionary Conservation of Vertebrate Blood–Brain Barrier Chemoprotective Mechanisms inDrosophila
2009
Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-$alpha;
2003
Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging
2013 Standout
Structure and function of the blood–brain barrier
2009 Standout
Blood-Brain Barrier Transport of Cytokines: A Mechanism for Neuropathology
2005
Cancer Metastasis: Building a Framework
2006 Standout
Capture, crawl, cross: the T cell code to breach the blood–brain barriers
2012
Multi-protein assemblies underlie the mesoscale organization of the plasma membrane
2014 StandoutNobel
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
2001 Standout
Lipopolysaccharide-Activated Microglia Induce Dysfunction of the Blood–Brain Barrier in Rat Microvascular Endothelial Cells Co-Cultured with Microglia
2009
Involvement of ROS in BBB dysfunction
2009
Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry
2015 StandoutNobel
apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
2008
Glucose transport to the brain: A systems model
2005
NXY-059 for Acute Ischemic Stroke
2006
Lipoprotein receptors and a Disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans
2003
A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
2008 Standout
Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production
2005
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
The critical component to establish in vitro BBB model: Pericyte
2005
Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model
2010
In Search of the Astrocytic Factor(s) Modulating Blood–Brain Barrier Functions in Brain Capillary Endothelial Cells In Vitro
2005
Dynamics of CNS Barriers: Evolution, Differentiation, and Modulation
2005
Astrocytes enhance radical defence in capillary endothelial cells constituting the blood‐brain barrier
1999
Brain Endothelial Cells as Pharmacological Targets in Brain Tumors
2004
New Structural Scaffolds for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases
2011 StandoutNobel
Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease
2010
The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury
2012
Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer Disease
2012
Biodegradable polymeric nanoparticles as drug delivery devices
2001 Standout
Blood-brain barrier biology and methodology
1999
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Characterization and Modulation of the Transferrin Receptor on Brain Capillary Endothelial Cells
2004
Glial and neuronal control of brain blood flow
2010 StandoutNature
Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection
2015
Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer.
1998
Growth-factor reduced Matrigel source influences stem cell derived brain microvascular endothelial cell barrier properties
2016
Effects of hypoxia on endothelial/pericytic co-culture model of the blood–brain barrier
2004
Capillary pericytes regulate cerebral blood flow in health and disease
2014 StandoutNature
Differential effects of hydrocortisone and TNFα on tight junction proteins in an in vitro model of the human blood–brain barrier
2008
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
2008 Standout
Human blood-derived macrophages enhance barrier function of cultured primary bovine and human brain capillary endothelial cells
2003
Pericytes: Cell Biology and Pathology
2001
The dolichol pathway of N-linked glycosylation
1999
Glycosidases of the asparagine-linked oligosaccharide processing pathway
1994
Improved bioavailability to the brain of glycosylated Met-enkephalin analogs
2000
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
2019
Neuroimmunity and the Blood–Brain Barrier: Molecular Regulation of Leukocyte Transmigration and Viral Entry into the Nervous System with a Focus on NeuroAIDS
2006
Advances in osmotic opening of the blood-brain barrier to enhance CNS chemotherapy
2001
Vesicular and conductive mechanisms of nucleotide release
2012
Claudin-1 induced sealing of blood–brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis
2011
Preparation of glial extracellular matrix: a novel method to analyze glial–endothelial cell interaction
1997
Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood–brain barrier
2003
Use of cyclodextrins to manipulate plasma membrane cholesterol content: Evidence, misconceptions and control strategies
2007
Tight Junctions of the Blood–Brain Barrier
2000
Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture
2005
Cancer immunotherapy comes of age
2011 StandoutNature
Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat
2006
Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models
2011
Blood-brain barrier dysfunction in disorders of the developing brain
2015
Mutants of the CMP-sialic Acid Transporter Causing the Lec2 Phenotype
1998
The role of the blood–CNS barrier in CNS disorders and their treatment
2009
Origin and physiological roles of inflammation
2008 StandoutNature
Bioavailability and Transport of Peptides and Peptide Drugs into the Brain
1997
Neurological autoimmunity targeting aquaporin-4
2009
Survey of the year 2003 commercial optical biosensor literature
2004
A survey of the year 2002 commercial optical biosensor literature
2003
Differentiation of Brain Endothelial Cells in Cell Culture
1991
Osmotic Opening of the Blood–Brain Barrier: Principles, Mechanism, and Therapeutic Applications
2000
Glial Cell Line-Derived Neurotrophic Factor Induces Barrier Function of Endothelial Cells Forming the Blood–Brain Barrier
1999
Nicotine and Cotinine Modulate Cerebral Microvascular Permeability and Protein Expression of ZO-1 through Nicotinic Acetylcholine Receptors Expressed on Brain Endothelial Cells
2002
Synthetic glycopeptides and glycoproteins as tools for biology
2004 StandoutNobel
Brain endothelial cells and the glio-vascular complex
2008
Erythropoietin protects the in vitro blood–brain barrier against VEGF‐induced permeability
2003
Chapter 19: The development of ion regulation at the blood-brain barrier
1992
The role of shear stress in Blood-Brain Barrier endothelial physiology
2011
Structural and functional aspects of the blood-brain barrier
2003
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
The blood–brain barrier: an overview
2004 Standout
The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier Aβ Clearance in Alzheimers Disease
2008
Pericytes regulate the blood–brain barrier
2010 StandoutNature
The blood–brain barrier in health and disease
2012
A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease
2001
Impaired blood–brain and blood–spinal cord barriers in mutant SOD1-linked ALS rat
2009
Re‐evaluating the role of astrocytes in blood‐brain barrier induction
1993
Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models
2004
The Complementary Membranes Forming the Blood‐Brain Barrier
2002
Role of Liver and Plasma Lipoproteins in Selective Transport of n-3 Fatty Acids to Tissues: A Comparative Study of 14C-DHA and 3H-Oleic Acid Tracers
2007
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
Novel models for assessing blood–brain barrier drug permeation
2012
Structure of the Blood–Brain Barrier and Its Role in the Transport of Amino Acids
2006
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
The Blood‐Brain Barrier and Its Role in Inflammation
2000
In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain
2006
Expression cloning of the Golgi CMP-sialic acid transporter.
1996
Biologically active quinoline and quinazoline alkaloids part I
2017
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier
1992
Effect of astroglial cells on hypoxia-induced permeability in PBMEC cells
2000
Tight junctions of the blood-brain barrier: development, composition and regulation.
2002
Interendothelial Claudin-5 Expression Depends on Cerebral Endothelial Cell–Matrix Adhesion by β1-Integrins
2011
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Receptor-Mediated Transport of Lactoferrin into the Cerebrospinal Fluid via Plasma in Young Calves
2003
Induction of Blood‐Brain Barrier Characteristics in Bovine Brain Endothelial Cells by Rat Astroglial Cells in Transfilter Coculturea
1991
Biologically active quinoline and quinazoline alkaloids part II
2018
Transport of small molecules through the blood-brain barrier: biology and methodology
1995
Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier
2014
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
In vivo metabolic labeling of sialoglycans in the mouse brain by using a liposome-assisted bioorthogonal reporter strategy
2016
Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
2020 StandoutNobel
Anin vitroblood–brain barrier model: Cocultures between endothelial cells and organotypic brain slice cultures
1998
1,500 scientists lift the lid on reproducibility
2016 StandoutNature
Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases
2003 Standout
A cell culture model of the blood-brain barrier.
1991
Response of the cerebral vasculature following traumatic brain injury
2017
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation
2002
Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
2011 Standout
F‐domain valency determines outcome of signaling through the angiopoietin pathway
2021 StandoutNobel
Intracellular Functions of N-Linked Glycans
2001 StandoutScience
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
Physiology and pharmacological role of the blood-brain barrier.
2009
Nitric oxide mediates hypoxia-induced changes in paracellular permeability of cerebral microvasculature
2004
Postischemic Attenuation of Cerebral Artery Reactivity Is Increased in the Presence of Tissue Plasminogen Activator
2000
Angiopoietin1/TIE2 and VEGF/FLK1 Induced by MSC Treatment Amplifies Angiogenesis and Vascular Stabilization after Stroke
2007
Transforming Growth Factor-β Mediates Astrocyte-Specific Regulation of Brain Endothelial Anticoagulant Factors
1999
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes
1997
A Chemical Reporter Strategy to Probe Glycoprotein Fucosylation
2006 StandoutNobel
Microgel, nanogel and hydrogel–hydrogel semi-IPN composites for biomedical applications: synthesis and characterization
2006
Angiopoietin-1 reduces vascular endothelial growth factor-induced brain endothelial permeability via upregulation of ZO-2
1998
Identification of an essential endogenous regulator of blood–brain barrier integrity, and its pathological and therapeutic implications
2012
Nanoparticulate systems for brain delivery of drugs
2012
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Imaging the glycome
2008 StandoutNobel
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Agrin, Aquaporin-4, and Astrocyte Polarity as an Important Feature of the Blood-Brain Barrier
2009
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
An Apolipoprotein E-Derived Peptide Mediates Uptake of Sterically Stabilized Liposomes into Brain Capillary Endothelial Cells
2005
Core/Shell Nanoparticles: Classes, Properties, Synthesis Mechanisms, Characterization, and Applications
2011 Standout
ABCC Drug Efflux Pumps and Organic Anion Uptake Transporters in Human Gliomas and the Blood-Tumor Barrier
2005
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Simultaneously electrogenerated diene and dienophile: A unique access to novel polyfunctionalized 1,4-benzoxazine derivatives as neuroprotective agents
2005
Fucose: biosynthesis and biological function in mammals
2003
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier
2011
CNS pericytes: Concepts, misconceptions, and a way out
2009
Injury and repair in the neurovascular unit
2012
Targeted delivery across the blood–brain barrier
2005
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression
2003
Angiogenesis of the blood‐brain barrier in vitro and the function of cerebral pericytes
2002
Culture-Induced Changes in Blood—Brain Barrier Transcriptome: Implications for Amino-Acid Transporters in vivo
2009
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse
1999 StandoutScience
Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells
2006
Works of Roméo Cecchelli being referenced
Tumor Necrosis Factor‐α Increases Lactoferrin Transcytosis Through the Blood‐Brain Barrier
1999
Receptor-mediated Transcytosis of Lactoferrin through the Blood-Brain Barrier
1999
Exposure of tumor necrosis factor‐α to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
1995
Behavior of α-, β-, and γ-Cyclodextrins and Their Derivatives on an in Vitro Model of Blood-Brain Barrier
2004
Modelling the Neurovascular Unit and the Blood-Brain Barrier with the Unique Function of Pericytes
2011
Bovine Brain Endothelial Cells Express Tight Junctions and Monoamine Oxidase Activity in Long‐Term Culture
1989
Mouse syngenic in vitro blood–brain barrier model: a new tool to examine inflammatory events in cerebral endothelium
2005
An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro
1990
Endothelin-1 as a Mediator of Endothelial Cell–Pericyte Interactions in Bovine Brain Capillaries
1997
Hypoxia Increases the Susceptibility to Oxidant Stress and the Permeability of the Blood‐Brain Barrier Endothelial Cell Monolayer
1995
Heparin Oligosaccharides that Pass the Blood‐Brain Barrier Inhibit β‐Amyloid Precursor Protein Secretion and Heparin Binding to β‐Amyloid Peptide
1998
Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood–brain barrier
2004
Physiological Pathway for Low-Density Lipoproteins across the Blood-Brain Barrier: Transcytosis through Brain Capillary Endothelial Cells In Vitro
2008
Prediction of Drug Transport Through the Blood-Brain Barrier in Vivo: A Comparison Between Two in Vitro Cell Models
2002
P‐glycoprotein in blood–brain barrier endothelial cells: interaction and oligomerization with caveolins
2003
Effects of tumor necrosis factor on receptor-mediated endocytosis and barrier functions of bovine brain capillary endothelial cell monolayers
1997
Understanding the blood–brain barrier using gene and protein expression profiling technologies
2009
Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells
2009
Down‐regulation of caveolin‐1 in glioma vasculature: Modulation by radiotherapy
2003
A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells
2014
Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood–brain barrier during ischaemia
2002
Drug Transfer Across the Blood‐Brain Barrier: Correlation Between In Vitro and In Vivo Models
1992
Blood–Brain Barrier Pericytes Are the Main Source of γ‐Glutamyltranspeptidase Activity in Brain Capillaries
1992
Differential expression of selectins by mouse brain capillary endothelial cells in vitro in response to distinct inflammatory stimuli
2005
Case study: adapting in vitro blood–brain barrier models for use in early-stage drug discovery
2011
Hypoxia Dramatically Increases the Nonspecific Transport of Blood‐Borne Proteins to the Brain
1997
Modelling of the blood–brain barrier in drug discovery and development
2007
Indirect Evidence that Drug Brain Targeting Using Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles Is Related to Toxicity
1999
High transcytosis of melanotransferrin (P97) across the blood–brain barrier
2002
Transport Screening of Drug Cocktails Through an in Vitro Blood-Brain Barrier: Is It a Good Strategy for Increasing the Throughput of the Discovery Pipeline?
2004
The neuroprotective activity of 8-alkylamino-1,4-benzoxazine antioxidants
2001
In vitro models for the blood–brain barrier
2004
Low‐Density Lipoprotein Receptor on Endothelium of Brain Capillaries
1989
In vitro blood–brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions
2002
Endothelial calcium dynamics, connexin channels and blood–brain barrier function
2013
Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin
2016
A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier
1997
VEGF-Induced BBB Permeability is Associated with an MMP-9 Activity Increase in Cerebral ischemia: Both Effects Decreased by ANG-1
2005
Membrane transport of sugar donors to the glycosylation sites
1987
Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells
1996
Intralumenal pool and transport of CMP-N-acetylneuraminic acid, GDP-fucose and UDP-galactose. Study with plasma-membrane-permeabilized mouse thymocytes
1984
Oxygen Glucose Deprivation Switches the Transport of tPA Across the Blood–Brain Barrier From an LRP-Dependent to an Increased LRP-Independent Process
2005
Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood–Brain Barrier Endothelium
2010
Stroke-Induced Brain Parenchymal Injury Drives Blood–Brain Barrier Early Leakage Kinetics: A Combined in Vivo/in Vitro Study
2013
Evaluation of Effect of Charge and Lipid Coating on Ability of 60-nm Nanoparticles to Cross an In Vitro Model of the Blood-Brain Barrier
1999
Catabolic pathway of oligosaccharide-diphospho-dolichol. Study of the fate of the oligosaccharidic moiety in mouse splenocytes
1987
Tissue-Type Plasminogen Activator Crosses the Intact Blood-Brain Barrier by Low-Density Lipoprotein Receptor–Related Protein-Mediated Transcytosis
2005
In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
2016
Mechanism of UDP‐sugar transport into intracellular vesicles
1986
Connexin Channels Provide a Target to Manipulate Brain Endothelial Calcium Dynamics and Blood—Brain Barrier Permeability
2011