Citation Impact
Citing Papers
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
2006
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
2010 StandoutScience
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
A Light-Actuated Nanovalve Derived from a Channel Protein
2005 StandoutScienceNobel
Lymphoid Hyperplasia, Autoimmunity, and Compromised Intestinal Intraepithelial Lymphocyte Development in Colitis-Free Gnotobiotic IL-2-Deficient Mice
1998
Functional diversity of helper T lymphocytes
1996 StandoutNature
Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis
2006
Safety and Efficacy of ABT-874, a Fully Human Interleukin 12/23 Monoclonal Antibody, in the Treatment of Moderate to Severe Chronic Plaque Psoriasis
2008
Genes responsible for human hereditary deafness: symphony of a thousand
1996
Inflammation and cancer
2002 StandoutNature
The anatomical basis of intestinal immunity
1997
Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
1994
Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity
2007
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
2002 StandoutNature
Mechanism and Regulation of Immunoglobulin Isotype Switching
1993
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
2005
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
2008 Standout
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
Pathogenesis and therapy of psoriasis
2007 StandoutNature
NF-κB in cancer: from innocent bystander to major culprit
2002 Standout
Regulatory T Cells
2000 StandoutNobel
A Human Interleukin-12/23 Monoclonal Antibody for the Treatment of Psoriasis
2007
Issues in T‐helper 1 development – resolved and unresolved
2004
Hydrophilicity of a Single Residue within MscL Correlates with Increased Channel Mechanosensitivity
1999
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
2003
A Long Twentieth Century of the Cell Cycle and Beyond
2000 StandoutNobel
Development of Th1-type immune responses requires the type I cytokine receptor TCCR
2000 Nature
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
IL-12 in Autoimmunity
1998
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
The development of allergic inflammation
2008 StandoutNature
NOD2 is a negative regulator of Toll-like receptor 2–mediated T helper type 1 responses
2004
Inflammatory Skin Disease in K14/p40 Transgenic Mice: Evidence for Interleukin-12-Like Activities of p40
2001
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 StandoutNature
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
2008
Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice
2001
IL‐1, IL‐18, and IL‐33 families of cytokines
2008
Chemically Charging the Pore Constriction Opens the Mechanosensitive Channel MscL
2001
Osteoclast differentiation and activation
2003 StandoutNature
A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes
2007
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Cells and Cytokines in the Pathogenesis of Inflammatory Bowel Disease: New Insights from Mouse T Cell Transfer Models
2000
Transcriptional repressor Blimp-1 regulates T cell homeostasis and function
2006
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
The Inflammasomes
2010 Standout
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
1999
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
Connexin 26 mutations in hereditary non-syndromic sensorineural deafness
1997 StandoutNature
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Interleukin-12, interleukin-23, and psoriasis: Current prospects
2007
The Inhibitory Effects of Transforming Growth Factor-Beta-1 (TGF-β1) in Autoimmune Diseases
2000
Points of control in inflammation
2002 StandoutNature
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Vasoactive intestinal peptide specifically induces human IgA1 and IgA2 production
1994
Regulatory T cells and inflammatory bowel disease
1999
Chronic T Cell-Mediated Enteropathy in Rural West African Children: Relationship with Nutritional Status and Small Bowel Function
2003
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis
2004
The Mammalian Degenerin MDEG, an Amiloride-sensitive Cation Channel Activated by Mutations Causing Neurodegeneration in Caenorhabditis elegans
1996
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
Helicobacter hepaticusTriggers Colitis in Specific-Pathogen-Free Interleukin-10 (IL-10)-Deficient Mice through an IL-12- and Gamma Interferon-Dependent Mechanism
1998
In Vitro and In Situ Expression of IL-23 by Keratinocytes in Healthy Skin and Psoriasis Lesions: Enhanced Expression in Psoriatic Skin
2006
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Down-regulation of MicroRNA-31 in CD4+ T Cells Contributes to Immunosuppression in Human Sepsis by Promoting TH2 Skewing
2016
REGULATION OF IMMUNE RESPONSES BY TGF-β
1998 Standout
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
How Cells Get the Right Chromosomes
1997 Science
Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora
2002 StandoutScienceNobel
Factors Involved in the Differentiation of TGF-β-Producing Cells from Naive CD4+ T Cells: IL-4 and IFN-γ Have Opposing Effects, While TGF-β Positively Regulates Its Own Production
1998
Induction of colitis by a CD4+T cell clone specific for a bacterial epitope
2003
Targeted Deletion of the IgA Constant Region in Mice Leads to IgA Deficiency with Alterations in Expression of Other Ig Isotypes
1999
Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris
2002
Commensal Host-Bacterial Relationships in the Gut
2001 StandoutScience
Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice
1998
Functional Role of Type I and Type II Interferons in Antiviral Defense
1994 StandoutScience
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis
2006
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Network of dendritic cells within the muscular layer of the mouse intestine
2005 StandoutNobel
Expression of the integrin αEβ7identifies unique subsets of CD25+as well as CD25−regulatory T cells
2002
Activated Self-MHC-Reactive T Cells Have the Cytokine Phenotype of Th3/T Regulatory Cell 1 T Cells
2000
Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract
2005 StandoutScience
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
A Novel Model of Inflammatory Bowel Disease: Mice Deficient for the Multiple Drug Resistance Gene, mdr1a, Spontaneously Develop Colitis
1998
Genetically targeted cell disruption in Caenorhabditis elegans
1997 StandoutNobel
Oxazolone Colitis: A Murine Model of T Helper Cell Type 2 Colitis Treatable with Antibodies to Interleukin 4
1998
The molecular basis of T helper 1 and T helper 2 cell differentiation
2000
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
Systemic autoimmune disease as a consequence of defective lymphocyte death
1997
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Cytokine therapeutics: lessons from interferonalpha.
1994
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Treatment of Murine Colitis by Lactococcus lactis Secreting Interleukin-10
2000 Science
The Disease Spectrum ofHelicobacter Pylori: The Immunopathogenesis of Gastroduodenal Ulcer and Gastric Cancer
2000
MECHANOSENSITIVE CHANNELS OFESCHERICHIA COLI:The MscL Gene, Protein, and Activities
1997
Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.
1998
T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment.
1997
Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation
1999 StandoutScience
Works of Rolf O. Ehrhardt being referenced
Blockade of Experimental Atopic Dermatitis via Topical NF-κB Decoy Oligonucleotide
2006
Reciprocal IFN-γ and TGF-β responses regulate the occurrence of mucosal inflammation
1997
Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice
1993
IL-12, Independently of IFN-γ, Plays a Crucial Role in the Pathogenesis of a Murine Psoriasis-Like Skin Disorder
1999
Induction and prevention of colonic inflammation in IL-2-deficient mice.
1997
Role of IFN-γ in Th1 Differentiation: IFN-γ Regulates IL-18Rα Expression by Preventing the Negative Effects of IL-4 and by Inducing/Maintaining IL-12 Receptor β2 Expression
2002
T Helper Type 2 Cell Differentiation Occurs in the Presence of Interleukin 12 Receptor β2 Chain Expression and Signaling
2000
Effect of transforming growth factor (TGF)-beta 1 on IgA isotype expression. TGF-beta 1 induces a small increase in sIgA+ B cells regardless of the method of B cell activation
1992
TGF-beta production regulates the development of the 2,4,6-trinitrophenol-conjugated keyhole limpet hemocyanin-induced colonic inflammation in IL-2-deficient mice.
1997
Dysregulated intrathymic development in the IL-2-deficient mouse leads to colitis-inducing thymocytes.
1997
Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice
1994
IL-12, independently of IFN-gamma, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder.
1999