Standout Papers
Citation Impact
Citing Papers
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Molecular biology and genetics of prion diseases
1994 StandoutNobel
Transgenetic investigations of prion diseases of humans and animals
1993 StandoutNobel
Purification and properties of the cellular prion protein from Syrian hamster brain
1992 StandoutNobel
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Determination of preferential binding sites for anti-dsRNA antibodies on double-stranded RNA by scanning force microscopy
2000
Chemistry and biology of prions
1992
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
1993
Regional distribution of protease‐resistant prion protein in fatal familial insomnia
1995
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
2005
BIOLOGY AND GENETICS OF PRION DISEASES
1994
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
Molecular basis of phenotypic variability in sporadc creudeldt‐jakob disease
1996
Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity
1993 Nobel
Prion Protein Peptides Induce .alpha.-Helix to .beta.-Sheet Conformational Transitions
1995
Prion Protein Isoforms, a Convergence of Biological and Structural Investigations
1995 StandoutNobel
The Neurochemistry of Prion Diseases
1993
Mice with gene targetted prion protein alterations show that Prnp, Sine and Prni are congruent
1998
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Genetic and Infectious Prion Diseases
1993
Developmental expression of the prion protein gene in glial cells
1995
Molecular biology of transmissible spongiform encephalopathies
1996
Scrapie strains retain their distinctive characteristics following passages of homogenates from different brain regions and spleen.
1997
Selective Neuronal Targeting in Prion Disease
1997 StandoutNobel
Mutant and Infectious Prion Proteins Display Common Biochemical Properties in Cultured Cells
1996
Fatal Familial Insomnia and Familial Creutzfeldt‐Jakob Disease: Clinical, Pathological and Molecular Features
1995
The abnormal isoform of the prion protein accumulates in late‐endosome‐like organelles in scrapie‐infected mouse brain
1995
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes
1993
Molecular biology of prion diseases
1994
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Local Supercoil-Stabilized DNA Structure
1991
Deadly Conformations—Protein Misfolding in Prion Disease
1997
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts
1991
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments
1997 StandoutNobel
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
1994 StandoutNobel
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
1993 StandoutNobel
Prion protein NMR structure and familial human spongiform encephalopathies
1998 StandoutNobel
Regional mapping of prion proteins in brain.
1992 StandoutNobel
Chemical chaperones interfere with the formation of scrapie prion protein.
1996 StandoutNobel
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
1997 StandoutNobel
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.
1993 Standout
GENETICS OF PRIONS
1997 StandoutNobel
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Prion Diseases and Neurodegeneration
1994 StandoutNobel
Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity
1996 StandoutNobel
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
1996 StandoutNobel
Attempts to restore scrapie prion infectivity after exposure to protein denaturants.
1993
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
Propagation of prion strains through specific conformers of the prion protein
1997 StandoutNobel
Prions
1998 StandoutNobel
NMR solution structure of the human prion protein
2000 StandoutNobel
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
1997 StandoutNobel
Structure of the recombinant full-length hamster prion protein PrP(29–231): The N terminus is highly flexible
1997 StandoutNobel
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
High Prion and PrPSc Levels but Delayed Onset of Disease in Scrapie-Inoculated Mice Heterozygous for a Disrupted PrP Gene
1994
Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform.
1993
Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy
1994
NMR structure of the bovine prion protein
2000 StandoutNobel
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
1994 StandoutNobel
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Etiology and pathogenesis of prion diseases.
1995 StandoutNobel
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
Inherited prion diseases.
1994 StandoutNobel
Recombinant scrapie-like prion protein of 106 amino acids is soluble
1996 StandoutNobel
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
1993 StandoutNobel
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism.
1994
Works of Rolf Hecker being referenced
Glycosylinositol Phospholipid Anchors of the Scrapie and Cellular Prion Proteins Contain Sialic Acid
1992 StandoutNobel
Analysis of RNA structures by temperature-gradient gel electrophoresis: viroid replication and processing
1988
TLR9−/− and TLR9+/+ mice display similar immune responses to a DNA vaccine
2004
Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters.
1992 StandoutNobel