Citation Impact
Citing Papers
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
1988 Standout
The evolving role of natural products in drug discovery
2005 Standout
The p53 proto-oncogene can act as a suppressor of transformation
1989 Standout
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
1988 StandoutNature
Induction of apoptosis in fibroblasts by c-myc protein
1992 Standout
Podophyllotoxin, steganacin and combretastatin: Natural products that bind at the colchicine site of tubulin
1993
Induction of hypoxia‐inducible factor‐1 (HIF‐1) and its target genes following focal ischaemia in rat brain
1999 StandoutNobel
A Trimeric Protein Complex Functions as a Synaptic Chaperone Machine
2001 StandoutNobel
Inhibition of N‐methyl‐N′'‐nitro‐n‐nitrosoguanidine‐induced methotrexate and adriamycin resistance in CHO cells by adeno‐associated virus type 2
1990 StandoutNobel
Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
1995 Standout
β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC
2000 StandoutNobel
Reflecting on 25 years with MYC
2008 Standout
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Creation of human tumour cells with defined genetic elements
1999 StandoutNature
Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA
1988
Advances in Malignant Mesothelioma
2005 Standout
Association between src-kinases and the polyoma virus oncogene middle T-antigen requires PP2A and a specific sequence motif
1999
The genome of human papovavirus BKV
1979
Transformation mediated by the SV40 T antigens: Separation of the overlapping SV40 early genes with a retroviral vector
1984
T antigen is bound to a host protein in SY40-transformed cells
1979 StandoutNature
Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF
1982 Nature
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976
1993 Standout
The roles of individual polyoma virus early proteins in oncogenic transformation
1982 Nature
Sustained expression of the human protooncogene MYCN rescues rat embryo cells from senescence.
1988 StandoutNobel
The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor.
1985 StandoutNobel
Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the region coding for the carboxyl terminus of the T antigen
1979 StandoutNobel
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
1983 StandoutNature
Cellular responsiveness to growth factors correlates with a cell's ability to express the transformed phenotype
1983
Recombinant DNA molecules comprising bovine papilloma virus type 1 DNA linked to plasmid DNA are maintained in a plasmidial state both in rodent fibroblasts and in bacterial cells.
1982
Mechanisms of Tumor Promotion: Potential Role of Intercellular Communication
1983
Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli.
1985 StandoutNobel
New classes of viable deletion mutants in the early region of polyoma virus
1979
Post-transcriptional processing of simian virus 40 late transcripts in injected frog oocytes
1983 StandoutNobel
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
1984 StandoutNature
Construction and analysis of viable deletion mutants of polyoma virus
1979 StandoutNobel
Peptide growth factors
1984 StandoutNobel
Integration sites and sequence arrangement of SV40 DNA in a homogeneous series of transformed rat fibroblast lines
1980
Fate of viral DNA in nonpermissive cells infected with simian virus 40.
1981
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA
1983 StandoutNobel
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
1993 Standout
Characterization of t antigens in polyoma-infected and transformed cells
1978
Regulation of SV40 Gene Expression
1981
Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells.
1982
Nucleotide sequence deletions within the coding region for small-t antigen of simian virus 40
1979 StandoutNobel
Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens.
1986
High-efficiency transformation of mammalian cells by plasmid DNA.
1987 Standout
Epidermal growth factor or serum stimulation of rat fibroblasts induces an elevation in mRNA levels for lactate dehydrogenase and other glycolytic enzymes
1985
Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.
1986
Simian Virus 40 Small t Antigen Cooperates with Mitogen- Activated Kinases To Stimulate AP-1 Activity
1994
DNA sequence homology and chromosomal deletion at a site of SV40 DNA integration
1982 Nature
SV40 induces mesotheliomas in hamsters.
1993
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.
1986 Standout
Biological activities of lignans
1984 Standout
The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.
1990 Standout
Recombinant Retroviruses Encoding Simian Virus 40 Large T Antigen and Polyomavirus Large and Middle T Antigens
1986
Neoplastic transformation by the human gene N-myc.
1987 StandoutNobel
Neoplastic Transformation by the Human Gene N-myc
1987 StandoutNobel
Prostate cancer in a transgenic mouse.
1995 Standout
Selective killing of transformed rat cells by minute virus of mice does not require infectious virus production
1990
Properties of simian virus 40 small t antigen overproduced in bacteria
1981
Identification of a Novel Cellular TPR-Containing Protein, SGT, That Interacts with the Nonstructural Protein NS1 of Parvovirus H-1
1998
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
1987 Standout
Isolation of the Oncogene and Epidermal Growth Factor-Induced Transin Gene: Complex Control in Rat Fibroblasts
1986
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines.
1983
Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA.
1984 StandoutNobel
Transforming but not immortalizing oncogenes activate the transcription factor PEA1.
1988
SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen
1987
Expression of simian virus 40 early genes in transformed rat cells is correlated with maintenance of the transformed phenotype
1978
Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro
1985 StandoutScience
Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells.
1982
Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.
1983 Standout
Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.
1994
DNA sequence and genome organization of genital human papillomavirus type 6b.
1983 StandoutNobel
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.
1988 Standout
Patterns of Integration of DNA Microinjected into Cultured Mammalian Cells: Evidence for Homologous Recombination Between Injected Plasmid DNA Molecules
1982 StandoutNobel
Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture.
1984
Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.
1985
Purification of biologically active simian virus 40 small tumor antigen.
1983
The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle
1994 StandoutNobel
Organization and Transcription of the Simian Virus 40 Genome
1979
Transforming Growth Factor-β: Biological Function and Chemical Structure
1986 StandoutScience
Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells
1985 StandoutNature
The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions
1989
Negative autoregulation of c-myc transcription.
1990
Normal embryo fibroblasts release transforming growth factors in a latent form
1984
Introduction and Recovery of a Selectable Bacterial Gene from the Genome of Mammalian Cells
1982
Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity.
1994
Type beta transforming growth factor: a bifunctional regulator of cellular growth.
1985
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
2003 Standout
Polyoma DNA sequences involved in control of viral gene expression in murine embryonal carcinoma cells
1981 Nature
Phosphorylation of T-antigen and control T-antigen expression in cells transformed by wild-type and tsA mutants of simian virus 40
1979
New region of the simian virus 40 genome required for efficient viral transformation.
1978 StandoutNobel
Efficient selection for high-expression transfectants with a novel eukaryotic vector
1991 Standout
Loss of integrated viral DNA sequences in polyoma-transformed cells is associated with an active viral A function
1979
Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena
1982 StandoutNobel
Works of Roland Seif being referenced
Integration of the simian virus 40 genome into cellular DNA in temperature-sensitive (N) and temperature-insensitive (A) transformants of 3T3 rat and Chinese hamster lung cells
1980
Rat cells transformed by simian virus 40 give rise to tumor cells which contain no viral proteins and often no viral DNA.
1983
Rat Cells Transformed by Simian Virus 40 Give Rise to Tumor Cells Which Contain No Viral Proteins and Often No Viral DNA
1983
Factors which disorganize microtubules or microfilaments increase the frequency of cell transformation by polyoma virus
1980
Growth state of the cell early after infection with simian virus 40 determines whether the maintenance of transformation will be A-gene dependent or independent
1979
Conditions leading to the establishment of the N (a gene dependent) and A (a gene independent) transformed states after polyoma virus infection of rat fibroblasts
1978
Cyclic AMP specifically blocks proliferation of rat 3T3 cells transformed by polyomavirus
1987
Simian virus 40 small t antigen is not required for the maintenance of transformation but may act as a promoter (cocarcinogen) during establishment of transformation in resting rat cells
1979
Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus
1977
Roles of the T Antigens in Transformation by SV40
1980