Citation Impact

Citing Papers

Visualization of the movement of single histidine kinase molecules in live Caulobacter cells
2004 StandoutNobel
Antibiotic Sensitivity Profiles Determined with an Escherichia coli Gene Knockout Collection: Generating an Antibiotic Bar Code
2010
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
AcrB: a mean, keen, drug efflux machine
2019
The First Highly Enantioselective Rh-Catalyzed Enyne Cycloisomerization
2000
Multiple Mechanisms of Antimicrobial Resistance in Pseudomonas aeruginosa: Our Worst Nightmare?
2002 Standout
Single-molecule detection of efflux pump machinery in Pseudomonas aeruginosa
2003
Green Chemistry: Principles and Practice
2009 Standout
X-Ray Structural Characterization of a Monoorganotin Acid
2002
Exploiting genomics, genetics and chemistry to combat antibiotic resistance
2003
Highly Enantioselective Synthesis of 3‐Substituted Furanones by Palladium‐Catalyzed Kinetic Resolution of Unsymmetrical Allyl Acetates
2012 StandoutNobel
Intrinsic antibiotic resistance: Mechanisms, origins, challenges and solutions
2013
Recent advances in the stereoselective synthesis of tetrahydrofurans
2006
The Science of Antibiotic Discovery
2020 Standout
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Metal‐Catalyzed Enantioselective Allylation in Asymmetric Synthesis
2007 Standout
Enantioselective, transition metal catalyzed cycloisomerizations
2012
Fluoroquinolones: Action and Resistance
2003
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
Hospital-Acquired Infections Due to Gram-Negative Bacteria
2010 Standout
Drug combinations: a strategy to extend the life of antibiotics in the 21st century
2019
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Platforms for antibiotic discovery
2013
Ring closing metathesis in protic media by means of a neutral and polar ruthenium benzylidene complex
2002 StandoutNobel
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Multicomponent reactions for the synthesis of pyrroles
2010 Standout
Can a Ketone Be More Reactive than an Aldehyde? Catalytic Asymmetric Synthesis of Substituted Tetrahydrofurans
2018 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Interplay between Efflux Pumps May Provide Either Additive or Multiplicative Effects on Drug Resistance
2000
The stereocontrolled synthesis of enantiopure α-methano heterocycles and constrained amino acid analogs
1996
Chiral Monodentate Phosphine Ligand MOP for Transition-Metal-Catalyzed Asymmetric Reactions
2000
Unusual Dynamics and pKaShift at the Active Site of a Lead-Dependent Ribozyme
1997
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Catalysts for Suzuki−Miyaura Coupling Processes:  Scope and Studies of the Effect of Ligand Structure
2005 Standout
Palladium-catalyzed asymmetric synthesis of allylic alcohols from unsymmetrical and symmetrical racemic allylic carbonates featuring C–O-bond formation and dynamic kinetic resolution
2005
The Current State of Peptide Drug Discovery: Back to the Future?
2017
Mechanism and Activity of Ruthenium Olefin Metathesis Catalysts
2001 StandoutNobel
Cascade Cyclizations
1992
Kaskaden‐Cyclisierungen
1992
Gold-Catalyzed Cycloisomerizations of Enynes: A Mechanistic Perspective
2008 Standout
Recent advances in the synthesis of pyrroles by multicomponent reactions
2014 Standout
Bacterial Resistance to β-Lactam Antibiotics:  Compelling Opportunism, Compelling Opportunity
2005 Standout
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
A concise total synthesis of puberulic acid, a potent antimalarial agent
2014 StandoutNobel
The synthesis of 4,5-methano congeners of α-kainic and α-allo-kainic acids as probes for glutamate receptors
1996
The First Highly Enantioselective Rh-Catalyzed Enyne Cycloisomerization
2000
Riddle of Biofilm Resistance
2001 Standout
Olefin Metathesis and Beyond
2000 Standout
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Ring-Closing Metathesis in Methanol and Water
1998 StandoutNobel
Ring closing metathesis in water with or without surfactants in the presence of RuCl2(PPh3)2(CHPh)
2002
Chemoenzymatic Synthesis of Glycosylated Glucagon-like Peptide 1: Effect of Glycosylation on Proteolytic Resistance and in Vivo Blood Glucose-Lowering Activity
2009
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Direct pKa Measurement of the Active-Site Cytosine in a Genomic Hepatitis Delta Virus Ribozyme
2001 StandoutNobel
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Die Chemie vicinaler Diamine
1998
Cyclizations of N-Acyliminium Ions
2004 Standout
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations:  A Decade Update
2005 Standout
Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms.
2001
Examination of mercaptobenzyl sulfonates as catalysts for native chemical ligation: application to the assembly of a glycosylated Glucagon-Like Peptide 1 (GLP-1) analogue
2015 StandoutNobel
Synthesis, Structure, and Activity of Enhanced Initiators for Olefin Metathesis
2003 StandoutNobel
Bacterial Topoisomerase Inhibitors:  Quinolone and Pyridone Antibacterial Agents
2005
Optimization of Meropenem Minimum Concentration/MIC Ratio To Suppress In Vitro Resistance of Pseudomonas aeruginosa
2005
Ruthenium-Based Heterocyclic Carbene-Coordinated Olefin Metathesis Catalysts
2009 StandoutNobel
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
The Enterprise of Synthesis: From Concept to Practice
2012
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria
2015
Water-Soluble Ruthenium Alkylidenes:  Synthesis, Characterization, and Application to Olefin Metathesis in Protic Solvents
2000 StandoutNobel
Cycloisomerization of 1,6-enynes in organoaqueous medium: an efficient and eco-friendly access to furan derivatives. Synthesis of a key intermediate of podophyllotoxin
2001
The Development of L2X2RuCHR Olefin Metathesis Catalysts:  An Organometallic Success Story
2000 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Novel Reactivity of Ruthenium Alkylidenes in Protic Solvents:  Degenerate Alkylidene Proton Exchange
2001 StandoutNobel
Crown Ethers:  Sensors for Ions and Molecular Scaffolds for Materials and Biological Models
2004 Standout
Neuronal M3muscarinic acetylcholine receptors are essential for somatotroph proliferation and normal somatic growth
2009
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout

Works of Roger Léger being referenced

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization
2003
The relationship between physicochemical properties, In vitro activity and pharmacokinetic profiles of analogues of diamine-Containing efflux pump inhibitors
2003
Identification of CJC-1131-albumin bioconjugate as a stable and bioactive GLP-1(7–36) analog
2004
Human Growth Hormone-Releasing Factor (hGRF)1–29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long-Lasting GRF Analog
2005
Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa
2003
Studies Towards Asymmetric Catalyzed Metallo-ene Reactions
1997
Total Synthesis of the Lignan Antibiotic Burseran and a Novel Approach to the Podophyllotoxin Skeleton
1992
Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa : Novel Agents for Combination Therapy
2001
Inhibitors of Efflux Pumps in Pseudomonas aeruginosa Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin
1999
Expedient assembly of carbocyclic, heterocyclic, and polycyclic compounds by trimethylstannyl radical mediated carbocyclizations of dienes and trienes: a novel oxidative cleavage of the carbon-tin bond
1992
Rankless by CCL
2026