Citation Impact

Citing Papers

Homocysteine and vascular disease
1999 Standout
Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus
1993
Effects of Nitric Oxide on Adenylyl Cyclase Stimulation in N18TG2 Neuroblastoma Cells
1998
Amino acid neurotransmission: Dynamics of vesicular uptake
1996
Glutamate receptor ion channels
2005 Standout
Inhibition of Glutamate Uptake with ltrans‐Pyrrolidine‐2,4‐Dicarboxylate Potentiates Glutamate Toxicity in Primary Hippocampal Cultures
1993
International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors
2002 Standout
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
Altered glutamatergic transmission in neurological disorders: From high extracellular glutamate to excessive synaptic efficacy
1997
Codistribution analysis of elastin and related fibrillar proteins in early vertebrate development
2003
Memantine in Moderate-to-Severe Alzheimer's Disease
2003 Standout
3-Hydroxypyridazine 1-oxides as carboxylate bioisosteres: A new series of subtype-selective AMPA receptor agonists
2006
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Elastin Synthesis and Fiber Assemblya
1991
Descending control of pain
2002 Standout
Glutamate uptake
2001 Standout
Production of the gaseous signal molecule hydrogen sulfide in mouse tissues
2008
Hyposmolarity‐induced taurine release in cerebellar granule cells is associated with diffusion and not with high‐affinity transport
1991
Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
2002 Standout
Changes in Extracellular Amino Acids and Spontaneous Neuronal Activity During Ischemia and Extended Reflow in the CA1 of the Rat Hippocampus
1991
Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
2009
Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate
1996 Standout
A Functional Transsulfuration Pathway in the Brain Links to Glutathione Homeostasis
2006
The chemical nature of the main central excitatory transmitter: A critical appraisal based upon release studies and synaptic vesicle localization
1993
Neuronal-glial exchange of taurine during hypo-osmotic stress: A combined immunocytochemical and biochemical analysis in rat cerebellar cortex
1993
The high affinity uptake system for excitatory amino acids in the brain
1994
Domoic Acid Neurotoxicity in Cultured Cerebellar Granule Neurons Is Mediated Predominantly by NMDA Receptors that Are Activated as a Consequence of Excitatory Amino Acid Release
1997
The bioenergetics of neurotransmitter release
1991
Chemical models of epilepsy with some reference to their applicability in the development of anticonvulsants
1992
GABAA Receptor Channels
1994 Standout
Transporters forL‐glutamate: An update on their molecular pharmacology and pathological involvement
2006
High Affinity Glutamate Transporters: Regulation of Expression and Activity
1997
The Competitive Transport Inhibitor L‐trans‐pyrrolidine‐2,4‐dicarboxylate Triggers Excitotoxicity in Rat Cortical Neuron‐Astrocyte Co‐cultures via Glutamate Release rather than Uptake Inhibition
1996
Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression
2004
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
New inhibitors for the neutral amino acid transporter ASCT2 reveal its Na+‐dependent anion leak
2004
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Inhibition of l-glutamate uptake into synaptic vesicles
1992
Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin
2016 Standout
Competitive AMPA receptor antagonists
2006
Heterogeneity and Functional Properties of Subtypes of Sodium-Dependent Glutamate Transporters in the Mammalian Central Nervous System
1996
Transient changes in the presence of nitric oxide synthases and nitrotyrosine immunoreactivity after focal cortical lesions
1997
Glutamate transporter blockers for elucidation of the function of excitatory neurotransmission systems
2008
Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2
2005
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Characterization of taurine transport in human glioma GL15 cell line: Regulation by protein kinase C
1996
Fibulin-5/DANCE is essential for elastogenesis in vivo
2002 StandoutNatureNobel
Subunit-Specific Agonist Activity at NR2A-, NR2B-, NR2C-, and NR2D-Containing N-Methyl-d-aspartate Glutamate Receptors
2007
Atherosclerosis — An Inflammatory Disease
1999 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Uniquantal Release through a Dynamic Fusion Pore Is a Candidate Mechanism of Hair Cell Exocytosis
2014 StandoutNobel
Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
1999
Identification of a G Protein-coupled Receptor Specifically Responsive to β-Alanine
2004
Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex
1996
The glutamate uptake inhibitorl-trans-2,4-pyrrolidine dicarboxylate is neurotoxic in neonatal rat brain
1994
Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids
2012 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals
1997
Nontransportable Inhibitors Attenuate Reversal of Glutamate Uptake in Synaptosomes Following a Metabolic Insult
1999
General mechanisms of axonal damage and its prevention
2005
The Glutamate Transport Inhibitor L‐trans‐pyrrolidine‐2,4‐dicarboxylate Indirectly Evokes NMDA Receptor Mediated Neurotoxicity in Rat Cortical Cultures
1996
Kinetic Resolution and Stereoselective Synthesis of 3‐Substituted Aspartic Acids by Using Engineered Methylaspartate Ammonia Lyases
2013 StandoutNobel
Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia
2003 Standout
Synapsins as mediators of BDNF-enhanced neurotransmitter release
2000 StandoutNobel
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
The excitatory amino acid transporters: Pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes
2005
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease
1991 Standout
Homocysteine and Atherothrombosis
1998 Standout
The glutamatergic nerve terminal
1993
[12] Design and synthesis of conformationally constrained inhibitors of high-affinity, sodium-dependent glutamate transporters
1998
Mechanism of glutamate release from rat hippocampal slices during in vitro ischemia
1996
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
2013 Standout
Carrier-mediated release of neurotransmitters
1993
Homocysteic acid induces intraneuronal accumulation of neurotoxic Aβ42: Implications for the pathogenesis of Alzheimer's disease
2005
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
The Cystine/Glutamate Antiporter System x c in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
2012
Homocysteine as a Risk Factor for Vascular Disease
1997
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
THE SYNAPTIC VESICLE CYCLE
2004 StandoutNobel
Aquaporin-4 Water Channel Protein in the Rat Retina and Optic Nerve: Polarized Expression in Müller Cells and Fibrous Astrocytes
1998 StandoutNobel
Extracellular matrix 4: The elastic fiber
1993
Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines
1977
Short-Term Synaptic Plasticity
2002 Standout
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
Immunogold quantification of glutamate in two types of excitatory synapse with different firing patterns
1992
Acute decrease in net glutamate uptake during energy deprivation
2000
The natural history of homocystinuria due to cystathionine beta-synthase deficiency.
1985 Standout
Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity
2000
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain
1997 StandoutNobel
Metabolomics for Investigating Physiological and Pathophysiological Processes
2019
High‐Affinity Transport of γ‐Aminobutyric Acid, Glycine, Taurine, L‐Aspartic Acid, and L‐Glutamic Acid in Synaptosomal (P2) Tissue: A Kinetic and Substrate Specificity Analysis
1987
Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome
2006 StandoutScience
Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected].
1993
Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport
1995
Modulation of cyclic AMP metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in mouse lymphocytes.
1980 StandoutNobel
Creatine and Creatinine Metabolism
2000 Standout
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Physiology of Microglia
2011 Standout
Novel Injury Mechanism in Anoxia and Trauma of Spinal Cord White Matter: Glutamate Release via Reverse Na+-dependent Glutamate Transport
1999
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout

Works of Roger Griffiths being referenced

Improvements in an in-vitro assay for excitotoxicity by measurement of early gene (c-fos mRNA) levels
2004
Cytotoxic actions and effects on intracellular Ca2+ and cGMP concentrations of sulphur‐containing excitatory amino acids in cultured cerebral cortical neurons
1993
Neuroactive Sulphur Amino Acids Evoke a Calcium‐Dependent Transmitter Release from Cultured Neurones That Is Sensitive to Excitatory Amino Acid Receptor Antagonists
1989
Cysteine sulphinate (CSA) as an excitatory amino acid transmitter candidate in the mammalian central nervous system
1990
Inhibition by excitatory sulphur amino acids of the high-affinityl-glutamate transporter in synaptosomes and in primary cultures of cortical astrocytes and cerebellar neurons
1989
NMDA receptor-mediated cGMP synthesis in primary cultures of mouse cerebellar granule cells appears to involve neuron-astrocyte communication with NO operating as the intercellular messenger
1996
L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters
1994
Simultaneous measurement by HPLC of the excitatory amino acid transmitter candidates homocysteate and homocysteine sulphinate supports a predominant astrocytic localisation
1992
Synaptosomal plasma membrane transport of excitatory sulphur amino acid transmitter candidates: Kinetic characterisation and analysis of carrier specificity
1992
Excitatory sulphur amino acid-evoked neurotransmitter release from rat brain synaptosome fractions
1989
Glutamate uptake into synaptic vesicles—inhibition by sulphur amino acids
1991
Sulphur-containing excitatory amino acid-evoked Ca2+-independent release of d-[3H]aspartate from cultured cerebellar granule cells: The role of glutamate receptor activation coupled to reversal of the acidic amino acid plasma membrane carrier
1992
Characterization of the 1H-Cyclopentapyrimidine-2,4(1H,3H)-dione Derivative (S)-CPW399 as a Novel, Potent, and Subtype-Selective AMPA Receptor Full Agonist with Partial Desensitization Properties
2001
Stimulation of γ‐[3H]Aminobutyric Acid Release from Cultured Mouse Cerebral Cortex Neurons by Sulphur‐Containing Excitatory Amino Acid Transmitter Candidates: Receptor Activation Mediates Two Distinct Mechanisms of Release
1991
The biochemistry and pharmacology of excitatory sulphur-containing amino acids
1993
Excitatory-sulphur-amino-acid-evoked neurotransmitter release from synaptosomes and primary neuronal cultures
1990
BIOCHEMTCAL CHANGES IN THE BRAIN OF EXPERIMENTAL ANIMALS IN RESPONSE TO ELEVATED PLASMA HOMOCYSTINE AND METHIONINE
1976
Observations on the fate of cystathionine in rat brain
1976
Differential Changes in the Content of Amino Acid Neurotransmitters in Discrete Regions of the Rat Brain Prior to the Onset and During the Course of Homocysteine‐Induced Seizures
1986
A Rational Approach to the Design of Selective Substrates and Potent Nontransportable Inhibitors of the Excitatory Amino Acid Transporter EAAC1 (EAAT3). New Glutamate and Aspartate Analogues as Potential Neuroprotective Agents
2001
Studies on the use of skin fibroblasts for the measurement of cystathionine synthase activity with respect to homocystinuria
1976
Mutual Inhibition Kinetic Analysis of γ‐Aminobutyric Acid, Taurine, and β‐Alanine High‐Affinity Transport into Neurons and Astrocytes: Evidence for Similarity Between the Taurine and β‐Alanine Carriers in Both Cell Types
1986
Effect of Induced Elevated Plasma Levels of Homocystine and Methionine in Rats on Collagen and Elastin Structures
1976
Characterization of a structural glycoprotein from bovine ligamentum nuchae exhibiting dual amine oxidase activity
1981
Rankless by CCL
2026