Citation Impact
Citing Papers
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
2001 StandoutScience
Identification of two initiator elements in the bidirectional promoter of the human dihydrofolate reductase and mismatch repair protein 1 genes
1994
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.
1995
Current State of Preeclampsia Mouse Models: Approaches, Relevance, and Standardization
2021
Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage
1991
Animal models of preeclampsia; uses and limitations
2011
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins.
1992
Unrepaired DNA Breaks in p53-Deficient Cells Lead to Oncogenic Gene Amplification Subsequent to Translocations
2002
Telomeres shorten during ageing of human fibroblasts
1990 StandoutNatureNobel
Transcription elongation factor SII
2000
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein
1988 StandoutNatureNobel
Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine
1995 StandoutNatureNobel
The yeast gene MSH3 defines a new class of eukaryotic MutS homologues
1993
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
Karnofsky memorial lecture. Ode to methotrexate.
1993
Adenosine deaminase deficiency: molecular basis and recent developments
1995
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Memory of Extracellular Adenosine A2A Purinergic Receptor-mediated Signaling in Murine T Cells
1997 StandoutNobel
Angiotensin II Type 1–Receptor Activating Antibodies in Renal-Allograft Rejection
2005 Standout
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization
1988 StandoutNatureNobel
Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase
1996
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
1990 StandoutNatureNobel
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
soluble form of CD4 (T4) protein inhibits AIDS virus infection
1988 StandoutNatureNobel
Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter
1987
Activation of C. elegans cell death protein CED-9 by an ammo-acid substitution in a domain conserved in Bcl-2
1994 StandoutNatureNobel
The bidirectionally transcribed dihydrofolate reductase and rep-3a promoters are growth regulated by distinct mechanisms.
1995
Amplified DNA sequences in Y1 mouse adrenal tumor cells: association with double minutes and localization to a homogeneously staining chromosomal region.
1982
Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells
1983
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing.
1994
Genetics and cancer
1980
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
1996
Purification and characterization of double-stranded RNA adenosine deaminase from bovine nuclear extracts.
1994
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene
1989
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends
1980
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
The organization and amplification of two chromosomal domains containing drosophila chorion genes
1981
Molecular analysis of mbcl-2: Structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma
1987
Expression of thymidine kinase and dihydrofolate reductase genes in mammalian ts mutants of the cell cycle.
1985
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
A structure for amplified DNA
1983 StandoutNobel
Control of thymidine kinase mRNA during the cell cycle.
1987
Ethidium fluorescence assays. Part 1. Physicochemical studies
1979
Gene amplification and gene correction in somatic cells
1982 StandoutNobel
Epstein–Barr virus transforms precursor B cells even before immunoglobulin gene rearrangements
1984 StandoutNatureNobel
The purification of a human mismatch-binding protein and identification of its associated ATPase and helicase activities.
1992
Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.
1983
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches.
1994
Transcription termination and 3′ processing: the end is in site!
1985
Localization of nicotinic acetylcholine receptor alpha-subunit transcripts during myogenesis and motor endplate development in the chick.
1989
Transposition and amplification of oncogene-related sequences in human neuroblastomas
1983
Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: Possible mechanisms and relevance to tumor promotion
1981
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase
1978 Nature
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.
1987 StandoutNobel
The transcription factor TFIIS zinc ribbon dipeptide Asp-Glu is critical for stimulation of elongation and RNA cleavage by RNA polymerase II.
1994
GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells
1995 Science
Double minutes in human tumor cells
1982
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
1983 StandoutNatureNobel
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc
1984 StandoutNatureNobel
Serum β2-microglobulin binds to a T-cell differentiation antigen and increases its expression
1984 StandoutNatureNobel
Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes
1981
Control of Thymidylate Synthase mRNA Content and Gene Transcription in an Overproducing Mouse Cell Line
1985
Murine dihydrofolate reductase transcripts through the cell cycle.
1986
c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors
1985 Nature
Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines.
1981
Expression of a Bacterial Gene in Mammalian Cells
1980 StandoutScienceNobel
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
Cell cycle regulation of thymidylate synthetase gene expression in cultured mouse fibroblasts.
1980
Methotrexate resistance and gene amplification. Mechanisms and implications
1986
Genetic Interaction between Transcription Elongation Factor TFIIS and RNA Polymerase II
1992
The Tetrahymena ribozyme acts like an RNA restriction endonuclease
1986 StandoutNatureNobel
Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle.
1985
Somatic variants of the level of expression of a cell surface antigen.
1983 StandoutNobel
Heteroduplex repair in extracts of human HeLa cells
1991
Cell cycle regulation of transfected murine dihydrofolate reductase genes.
1986
Gene amplification in cultured animal cells
1984
Synthesis of immunoglobulin mu chain gene products precedes synthesis of light chains during B-lymphocyte development.
1981 Nobel
Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells.
1979
Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.
1995
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Gene Amplification and Drug Resistance in Cultured Murine Cells
1978 Science
Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.
1979
Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.
1978
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.
1990 StandoutNobel
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice.
1996
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor
1987 StandoutScienceNobel
Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesis.
1984
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Gene amplification in a leukemic patient treated with methotrexate.
1984
Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma.
1984
Cloning of DNA from double minutes of Y1 mouse adrenocortical tumor cells: Evidence for gene amplification
1981
Role of A2a Extracellular Adenosine Receptor-Mediated Signaling in Adenosine-Mediated Inhibition of T-Cell Activation and Expansion
1997 StandoutNobel
Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNA
1987 StandoutNobel
Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines.
1981
Resistance to methotrexate due to gene amplification in a patient with acute leukemia.
1984
Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.
1979
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Murine Dihydrofolate Reductase Transcripts Through the Cell Cycle
1986
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
1984 StandoutNature
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
Role of A2a Extracellular Adenosine Receptor-Mediated Signaling in Adenosine-Mediated Inhibition of T-Cell Activation and Expansion
1997 StandoutNobel
Animal Models of Preeclampsia
2020
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
Somatic generation of antibody diversity
1983 StandoutNatureNobel
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
Works of Rodney E. Kellems being referenced
Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice
2008
Developmental expression of adenosine deaminase in the upper alimentary tract of mice
1990
Deduced amino acid sequence of Escherichia coli adenosine deaminase reveals evolutionarily conserved amino acid residues: implications for catalytic function
1991
Metabolic and Immunologic Consequences of Limited Adenosine Deaminase Expression in Mice
1996
Recombinant Vascular Endothelial Growth Factor 121 Attenuates Autoantibody-Induced Features of Pre-eclampsia in Pregnant Mice
2010
Autoantibody-Mediated Angiotensin Receptor Activation Contributes to Preeclampsia Through Tumor Necrosis Factor-α Signaling
2010
Functional Analysis of a Stable Transcription Arrest Site in the First Intron of the Murine Adenosine Deaminase Gene
1993
Molecular cloning of the murine adenosine deaminase gene from a genetically enriched source: identification and characterization of the promoter region.
1986
Transcription of the Mouse Dihydrofolate Reductase Gene Proceeds Unabated Through Seven Polyadenylation Sites and Terminates Near a Region of Repeated DNA
1984
Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene.
1989
Amplification of Dihydrofolate Reductase Genes in Methotrexate-resistant Cultured Mouse Cells
1978
Hypoxia-Independent Upregulation of Placental Hypoxia Inducible Factor-1α Gene Expression Contributes to the Pathogenesis of Preeclampsia
2015
Independent 5' and 3'-end determination of multiple dihydrofolate reductase transcripts.
1987
Selective overproduction of adenosine deaminase in cultured mouse cells.
1983
Transglutaminase is a Critical Link Between Inflammation and Hypertension
2016
Control of dihydrofolate reductase messenger ribonucleic acid production.
1981
Adenosine deaminase deficiency and severe combined immunodeficiencies
1985
Dihydrofolate reductase gene expression in cultured mouse cells is regulated by transcript stabilization in the nucleus.
1984
Functional analysis of a stable transcription arrest site in the first intron of the murine adenosine deaminase gene.
1993
Identification and Characterization of Transcriptional Arrest Sites in Exon 1 of the Human Adenosine Deaminase Gene
1990
Analysis of the Mouse dhfr Promoter Region: Existence of a Divergently Transcribed Gene
1985
Angiotensin Receptor Agonistic Autoantibody–Mediated Tumor Necrosis Factor-α Induction Contributes to Increased Soluble Endoglin Production in Preeclampsia
2010
Synthesis and degradation of folate reductase in sensitive and methotrexate-resistant lines of S-180 cells.
1976
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice.
1995
Regulation of folate reductase synthesis in sensitive and methotrexate-resistant sarcoma 180 cells. In vitro translation and characterization of folate reductase mRNA.
1976
The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia
2009
Autoantibody-Mediated IL-6–Dependent Endothelin-1 Elevation Underlies Pathogenesis in a Mouse Model of Preeclampsia
2011
Identification and characterization of transcriptional arrest sites in exon 1 of the human adenosine deaminase gene.
1990
Dual Bidirectional Promoters at the Mouse dhfr Locus: Cloning and Characterization of Two mRNA Classes of the Divergently Transcribed Rep-1 Gene
1989
Analysis of the mouse dhfr promoter region: existence of a divergently transcribed gene.
1985
Excess LIGHT Contributes to Placental Impairment, Increased Secretion of Vasoactive Factors, Hypertension, and Proteinuria in Preeclampsia
2013
Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.
1978
Sequence requirements for transcriptional arrest in exon 1 of the human adenosine deaminase gene.
1991
Adenosine Deaminase Gene Expression
1989
Polyoma virus and cyclic AMP-mediated control of dihydrofolate reductase mRNA abundance in methotrexate-resistant mouse fibroblasts.
1979
Antibodies From Preeclamptic Patients Stimulate Increased Intracellular Ca 2+ Mobilization Through Angiotensin Receptor Activation
2004