Standout Papers

PKR-Dependent and -Independent Mechanisms Are Involved in Translational Shutoff during Sind... 2003 2026 2010 2018 106
  1. PKR-Dependent and -Independent Mechanisms Are Involved in Translational Shutoff during Sindbis Virus Infection (2004)
    Rodion Gorchakov, Elena I. Frolova et al. Journal of Virology
  2. Selection of Functional 5′ cis -Acting Elements Promoting Efficient Sindbis Virus Genome Replication (2003)
    Rodion Gorchakov, Richard W. Hardy et al. Journal of Virology

Citation Impact

Citing Papers

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Identification of interferon-stimulated genes that attenuate Ebola virus infection
2020 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery
2015
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Defining the proteolytic landscape during enterovirus infection
2020 StandoutNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication
2019 StandoutNobel
Translational resistance of late alphavirus mRNA to eIF2α phosphorylation: a strategy to overcome the antiviral effect of protein kinase PKR
2006
Modified mRNA Vaccines Protect against Zika Virus Infection
2017
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
Template requirements for recognition and copying by Sindbis virus RNA-dependent RNA polymerase
2006
trans-Complementation of an NS2 Defect in a Late Step in Hepatitis C Virus (HCV) Particle Assembly and Maturation
2009
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Zika virus: from an obscurity to a priority
2018
Dynamical features of thePlasmodium falciparumribosome during translation
2015 StandoutNobel
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Host responses to alphavirus infection
2008
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Tracking and Elucidating Alphavirus-Host Protein Interactions
2006 StandoutNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread
2017 StandoutNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro
2008
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Relating structure to evolution in class II viral membrane fusion proteins
2014
New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication Complexes
2016
Diversion of stress granules and P-bodies during viral infection
2013
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
2013 Standout
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
IFITM3 directly engages and shuttles incoming virus particles to lysosomes
2018 StandoutNobel
Interferon-inducible antiviral effectors
2008 Standout
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP)
2019 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Sindbis Virus Translation Is Inhibited by a PKR/RNase L-Independent Effector Induced by Alpha/Beta Interferon Priming of Dendritic Cells
2005
Genetic Analysis of the Carboxy-Terminal Region of the Hepatitis C Virus Core Protein
2009 StandoutNobel
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication
2010 StandoutNobel
Thiouracil Cross-Linking Mass Spectrometry: a Cell-Based Method To Identify Host Factors Involved in Viral Amplification
2013
Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis
2019
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
2007 Standout
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
2012 StandoutNobel
PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons
2006
Requirements at the 3′ End of the Sindbis Virus Genome for Efficient Synthesis of Minus-Strand RNA
2005 StandoutNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Identification of a Dominant Negative Inhibitor of Human Zinc Finger Antiviral Protein Reveals a Functional Endogenous Pool and Critical Homotypic Interactions
2010 StandoutNobel
Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome
2005
The C-Terminal Repeat Domains of nsP3 from the Old World Alphaviruses Bind Directly to G3BP
2014
Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection
2012
Increased Susceptibility to DNA Virus Infection in Mice with a GCN2 Mutation
2011 StandoutNobel
Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform
2013
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit
2016 StandoutNobel
Importance of eIF2α Phosphorylation and Stress Granule Assembly in Alphavirus Translation Regulation
2005
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
Inhibition of host translation by virus infection in vivo
2010
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Serologic Tools and Strategies to Support Intervention Trials to Combat Zika Virus Infection and Disease
2019
Eastern and Venezuelan Equine Encephalitis Viruses Differ in Their Ability To Infect Dendritic Cells and Macrophages: Impact of Altered Cell Tropism on Pathogenesis
2008
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel

Works of Rodion Gorchakov being referenced

Sindbis Virus Nonstructural Protein nsP2 Is Cytotoxic and Inhibits Cellular Transcription
2006
Inhibition of Transcription and Translation in Sindbis Virus-Infected Cells
2005
Development of Sindbis Viruses Encoding nsP2/GFP Chimeric Proteins and Their Application for Studying nsP2 Functioning
2007
A New Role for ns Polyprotein Cleavage in Sindbis Virus Replication
2008
Clinical, Virologic, and Immunologic Characteristics of Zika Virus Infection in a Cohort of US Patients: Prolonged RNA Detection in Whole Blood
2018
Different Types of nsP3-Containing Protein Complexes in Sindbis Virus-Infected Cells
2008
4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus
2011
Functional Sindbis Virus Replicative Complexes Are Formed at the Plasma Membrane
2010
Noncytopathic Replication of Venezuelan Equine Encephalitis Virus and Eastern Equine Encephalitis Virus Replicons in Mammalian Cells
2005
Prolonged Detection of Zika Virus in Vaginal Secretions and Whole Blood
2016
PKR-Dependent and -Independent Mechanisms Are Involved in Translational Shutoff during Sindbis Virus Infection
2004 StandoutNobel
Selection of Functional 5′ cis -Acting Elements Promoting Efficient Sindbis Virus Genome Replication
2003 StandoutNobel
Formation of nsP3-Specific Protein Complexes during Sindbis Virus Replication
2006
The Old World and New World Alphaviruses Use Different Virus-Specific Proteins for Induction of Transcriptional Shutoff
2006
Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication
2012
Attenuation of Chikungunya Virus Vaccine Strain 181/Clone 25 Is Determined by Two Amino Acid Substitutions in the E2 Envelope Glycoprotein
2012
Rankless by CCL
2026