Citation Impact
Citing Papers
CTLA-4 blockade increases IFNγ-producing CD4 + ICOS hi cells to shift the ratio of effector to regulatory T cells in cancer patients
2008
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
The ICOS/ICOSL Pathway Is Required for Optimal Antitumor Responses Mediated by Anti–CTLA-4 Therapy
2011
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
2010 Standout
Melanocyte antigen triggers autoimmunity in human psoriasis
2015
Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity
2006
Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis
2015 Science
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
2005
Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity
2012
SOCS-1 inhibits expression of the antiviral proteins 2′,5′-OAS and MxA induced by the novel interferon-λs IL-28A and IL-29
2005
Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals
2002
Induction of IL-17+ T Cell Trafficking and Development by IFN-γ: Mechanism and Pathological Relevance in Psoriasis
2008
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Cationic Host Defence Peptides: Potential as Antiviral Therapeutics
2013
The regulation of IL-10 production by immune cells
2010 Standout
A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis
2014
Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction
2005 Nature
Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps
2015
Netting neutrophils in autoimmune small-vessel vasculitis
2009 Standout
A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination
2016
The sweetness of the DNA backbone drives Toll-like receptor 9
2008
Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
2012
Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
2008
Psoriasis
2009 Standout
IL‐23 and the Th17 pathway promote inflammation and impair antifungal immune resistance
2007
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
2016
Type I interferons in Sjögren's syndrome
2012
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
2008
Development of TLR inhibitors for the treatment of autoimmune diseases
2008
The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
2013 StandoutNobel
The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium
2010
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice
2014
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
2010
LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs
2011
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense
2009
Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
2010 Nature
Ligation of Signal Inhibitory Receptor on Leukocytes-1 Suppresses the Release of Neutrophil Extracellular Traps in Systemic Lupus Erythematosus
2013
Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis
2009
Pattern Recognition Receptors and Inflammation
2010 Standout
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
2007
Antigen-Presentation Properties of Plasmacytoid Dendritic Cells
2008
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
2014 Standout
Psoriasis
2021 Standout
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
2008
Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery
2008
Intracellular Toll-like Receptors
2010 StandoutNobel
Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes
2016
Neutrophils in the activation and regulation of innate and adaptive immunity
2011 Standout
DNA released from dying host cells mediates aluminum adjuvant activity
2011
Interleukin-10 production by effector T cells: Th1 cells show self control
2007
Psoriasis pathogenesis and the development of novel targeted immune therapies
2017
Immune Signaling by RIG-I-like Receptors
2011
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The pathogenesis of psoriatic arthritis
2018
Taming cancer by inducing immunity via dendritic cells
2007
Choreographing Immunity in the Skin Epithelial Barrier
2019
Neutrophil extracellular traps in immunity and disease
2017 Standout
How dying cells alert the immune system to danger
2008
The DNA Sugar Backbone 2′ Deoxyribose Determines Toll-like Receptor 9 Activation
2008
The Human Antimicrobial Peptide LL-37, but Not the Mouse Ortholog, mCRAMP, Can Stimulate Signaling by Poly(I:C) through a FPRL1-dependent Pathway
2013
Immunity, Inflammation, and Cancer
2010 Standout
A cell biological view of Toll-like receptor function: regulation through compartmentalization
2009
Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
2011
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Innate immune recognition of viral infection
2006 Standout
A calculated response: control of inflammation by the innate immune system
2008
Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
2012
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Molecular Dissection of Psoriasis: Integrating Genetics and Biology
2009
Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics
2006 StandoutNobel
Role of the Interleukin (IL)-28 Receptor Tyrosine Residues for Antiviral and Antiproliferative Activity of IL-29/Interferon-λ1
2004
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Dendritic cells – why can they help and hurt us
2009
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
2017
Designing Vaccines Based on Biology of Human Dendritic Cell Subsets
2010
Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
2013
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Plasmacytoid dendritic cells in immunity
2004
Immunity to fungal infections
2011 Standout
Diversity in the contribution of interleukin‐10 to T‐cell‐mediated immune regulation
2008
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
2013
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Pathogen Recognition and Innate Immunity
2006 Standout
TH1 cells control themselves by producing interleukin-10
2007
The host type I interferon response to viral and bacterial infections
2005
Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose
2009
Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones
2012
Lambda Interferon Inhibits Hepatitis B and C Virus Replication
2005
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Highly Effective New Treatments for Psoriasis Target the IL-23/Type 17 T Cell Autoimmune Axis
2016
Lambda Interferon (IFN-λ), a Type III IFN, Is Induced by Viruses and IFNs and Displays Potent Antiviral Activity against Select Virus Infections In Vivo
2006
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Signal Inhibitory Receptor on Leukocytes-1 Limits the Formation of Neutrophil Extracellular Traps, but Preserves Intracellular Bacterial Killing
2016
IgA Enhances NETosis and Release of Neutrophil Extracellular Traps by Polymorphonuclear Cells via Fcα Receptor I
2014
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation
2016
The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular traps
2015
Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus
2011
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses
2010
Induction of the human cathelicidin LL-37 as a novel treatment against bacterial infections
2012
Contrasting roles for all-trans retinoic acid in TGF-β–mediated induction of Foxp3 and Il10 genes in developing regulatory T cells
2009
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
2005
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-α/β on antigen cross-presentation
2006 StandoutNobel
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis
2014
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease
2014
Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9
2010
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
2004 StandoutNobel
ICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated withHelicobacter pylori
2016 StandoutNobel
NET formation can occur independently of RIPK3 and MLKL signaling
2015
TLR accessory molecules
2008
Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process
2013
Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus
2011
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors
2004
Cathepsins are required for Toll-like receptor 9 responses
2008
TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA
2008
NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus
2012
Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure toAspergillus fumigatusConidia
2010
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
2009
Neutrophil extracellular traps exacerbate Th1‐mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation
2016
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain
2004
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Increased Neutrophil Elastase and Proteinase 3 and Augmented NETosis Are Closely Associated With β-Cell Autoimmunity in Patients With Type 1 Diabetes
2014
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities
2016 StandoutNobel
Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic Cells
2003
Immobilized Immune Complexes Induce Neutrophil Extracellular Trap Release by Human Neutrophil Granulocytes via FcγRIIIB and Mac-1
2014
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Pertussis Toxin by Inducing IL-6 Promotes the Generation of IL-17-Producing CD4 Cells
2007
A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis
2018
When two is better than one: macrophages and neutrophils work in concert in innate immunity as complementary and cooperative partners of a myeloid phagocyte system
2009
Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis
2015
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis
2013
Works of Roberto Lande being referenced
Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
2009
Plasmacytoid dendritic cells prime IL-10–producing T regulatory cells by inducible costimulator ligand
2007
Generation of IL-23 Producing Dendritic Cells (DCs) by Airborne Fungi Regulates Fungal Pathogenicity via the Induction of TH-17 Responses
2010
Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses
2010
Viral infection and Toll‐like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte‐derived dendritic cells
2004
Plasmacytoid Dendritic Cells in Multiple Sclerosis
2008
The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis
2014
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
2007 Nature
Native and Genetically Inactivated Pertussis Toxins Induce Human Dendritic Cell Maturation and Synergize with Lipopolysaccharide in Promoting T Helper Type 1 Responses
2002
Cell‐Mediated Immunity and Antibody Responses toBordetella pertussisAntigens in Children with a History of Pertussis Infection and in Recipients of an Acellular Pertussis Vaccine
2000
Differential responsiveness to IFN-α and IFN-β of human mature DC through modulation of IFNAR expression
2006
Cytosolic sensing of extracellular self-DNA transported into monocytes by the antimicrobial peptide LL37
2012
IFN-αβ Released by Mycobacterium tuberculosis-Infected Human Dendritic Cells Induces the Expression of CXCL10: Selective Recruitment of NK and Activated T Cells
2003
Characterization and Recruitment of Plasmacytoid Dendritic Cells in Synovial Fluid and Tissue of Patients with Chronic Inflammatory Arthritis
2004
Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus
2011
Antimicrobial peptides and self-DNA in autoimmune skin inflammation
2008
Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self‐DNA
2014
Human Dendritic Cells followingAspergillus fumigatusInfection Express the CCR7 Receptor and a Differential Pattern of Interleukin-12 (IL-12), IL-23, and IL-27 Cytokines, Which Lead to a Th1 Response
2006
Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis
2003