Standout Papers
Citation Impact
Citing Papers
Runaway domain swapping in amyloid-like fibrils of T7 endonuclease I
2006
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
A General Model of Prion Strains and Their Pathogenicity
2007 Science
Bovine Spongiform Encephalopathy (BSE): Causes and Consequences of a Common Source Epidemic
1997
An overview of human prion diseases
2011
Bacterial Contamination of Animal Feed and Its Relationship to Human Foodborne Illness
2002
Molecular biology and genetics of prion diseases
1994 StandoutNobel
Prion protein fate governed by metal binding
2004
The Crystal Structure of the Globular Domain of Sheep Prion Protein
2004
Unaltered susceptibility to BSE in transgenic mice expressing human prion protein
1995 Nature
Mammalian Prion Biology
2004
Folding and intrinsic stability of deletion variants of PrP(121–231), the folded C-terminal domain of the prion protein
2002
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Identification of Intermediate Steps in the Conversion of a Mutant Prion Protein to a Scrapie-like Form in Cultured Cells
1997
Detecting prion protein gene mutations by denaturing gradient gel electrophoresis
1994 StandoutNobel
First experimental transmission of fatal familial insomnia
1995 NatureNobel
Lack of prion protein expression results in a neuronal phenotype sensitive to stress
2001
Prions and Neurodegenerative Diseases
1987 StandoutNobel
Mutation of the Prion Protein in Libyan Jews with Creutzfeldt–Jakob Disease
1991 StandoutNobel
The 14-3-3 Brain Protein in Cerebrospinal Fluid as a Marker for Transmissible Spongiform Encephalopathies
1996
Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
1996 Nature
BIOLOGY AND GENETICS OF PRION DISEASES
1994
Scrapie prions: a three-dimensional model of an infectious fragment
1996
Prion diseases: Transmission from mad cows?
1996
Sensitive enzyme-linked immunosorbent assay for detection of PrPSc in crude tissue extracts from scrapie-affected mice
1997
Molecular basis of phenotypic variability in sporadc creudeldt‐jakob disease
1996
To what Extent is Strain Variation Evidence for an Independent Genome in the Agent of the Transmissible Spongiform Encephalopathies?
1996
Prion Protein Binds Copper within the Physiological Concentration Range
2001
Molecular properties of complexes formed between the prion protein and synthetic peptides
1997 StandoutNobel
Studies on peptide fragments of prion proteins
2001
Genetic and Infectious Prion Diseases
1993
Molecular biology of transmissible spongiform encephalopathies
1996
Immunologic and Molecular Biologic Studies of Prion Proteins in Bovine Spongiform Encephalopathy
1993 StandoutNobel
Selective Neuronal Targeting in Prion Disease
1997 StandoutNobel
Human prion diseases
1994 StandoutNobel
Fatal Familial Insomnia and Familial Creutzfeldt‐Jakob Disease: Clinical, Pathological and Molecular Features
1995
"Friendly fire" in medicine: hormones, homografts, and Creutzfeldt-Jakob disease
1992
Eight prion strains have PrPSc molecules with different conformations
1998 Nobel
Strain-specific prion-protein conformation determined by metal ions
1999
Crystal structure of the human prion protein reveals a mechanism for oligomerization.
2001
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy
2006
Human spongiform encephalopathy: The national institutes of health series of 300 cases of experimentally transmitted disease
1994 Nobel
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Deadly Conformations—Protein Misfolding in Prion Disease
1997
Transmission dynamics and epidemiology of BSE in British cattle
1996 Nature
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
A novel hamster prion protein mRNA contains an extra exon: increased expression in scrapie
1997
Molecular biology and pathogenesis of prion diseases
1996
The prion folding problem
1997
Fingerprinting food: current technologies for the detection of food adulteration and contamination
2012 Standout
NMR structures of three single-residue variants of the human prion protein
2000 StandoutNobel
Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
1996 StandoutNobel
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Neurodegenerative Diseases: Expanding the Prion Concept
2015
Transmissible spongiform encephalopathies: The threat of BSE to man
1990
Structure and polymorphism of the mouse prion protein gene.
1994 StandoutNobel
Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments
1997 StandoutNobel
Genetically Engineered Plants and Foods: A Scientist's Analysis of the Issues (Part II)
2009
Prion protein NMR structure and familial human spongiform encephalopathies
1998 StandoutNobel
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
1997 StandoutNobel
GENETICS OF PRIONS
1997 StandoutNobel
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Evolution of a Strain of CJD That Induces BSE-Like Plaques
1997 Science
Transmission of the BSE Agent to Mice in the Absence of Detectable Abnormal Prion Protein
1997 Science
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
1996 StandoutNobel
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
The new variant form of Creutzfeldt-Jakob disease: a novel prion protein amyloid disorder
1997
Biology and Genetics of Prions Causing Neurodegeneration
2013 Nobel
Emerging Infectious Diseases of Wildlife-- Threats to Biodiversity and Human Health
2000 StandoutScience
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
1997 StandoutNobel
Predicting the CJD epidemic in humans
1997 Nature
BSE and Prions: Uncertainties About the Agent
1998 Science
Propagation of prion strains through specific conformers of the prion protein
1997 StandoutNobel
Prions
1998 StandoutNobel
NMR solution structure of the human prion protein
2000 StandoutNobel
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
1997 StandoutNobel
Transmissible and non-transmissible neurodegenerative disease: similarities in age of onset and genetics in relation to aetiology
1986
Structure of the recombinant full-length hamster prion protein PrP(29–231): The N terminus is highly flexible
1997 StandoutNobel
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie.
1994 StandoutNobel
NMR structure of the bovine prion protein
2000 StandoutNobel
Copper Coordination in the Full-Length, Recombinant Prion Protein
2003 Nobel
Prevention of Scrapie Pathogenesis by Transgenic Expression of Anti-Prion Protein Antibodies
2001 Science
Recombinant prion protein does not possess SOD-1 activity
2005
Food Security: The Challenge of Feeding 9 Billion People
2010 StandoutScience
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
1994 StandoutNobel
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
Etiology and pathogenesis of prion diseases.
1995 StandoutNobel
Oxidative and Inflammatory Events in Prion Diseases: Can They Be Therapeutic Targets?
2019
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
The immunobiology of TSE diseases
2001
Prion research: the next frontiers
1997 Nature
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
Prion diseases of humans and animals
1996 StandoutNobel
Recombinant scrapie-like prion protein of 106 amino acids is soluble
1996 StandoutNobel
Prion protein NMR structure and species barrier for prion diseases
1997 StandoutNobel
Creutzfeldt‐Jakob disease: Clinical analysis of a consecutive series of 230 neuropathologically verified cases
1986 Nobel
Copper binding to the prion protein: Structural implications of four identical cooperative binding sites
1999 Nobel
The antiviral compound HPA-23 can prevent scrapie when administered at the time of infection
1983
Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
1992 StandoutNobel
Amyloid Fibrils of the HET-s(218–289) Prion Form a β Solenoid with a Triangular Hydrophobic Core
2008 Science
Works of Robert Will being referenced
Bovine spongiform encephalopathy in a cow in the United Kingdom
1989
Epidemiology of Creutzfeldt-Jakob disease
1993
Sporadic Creutzfeldt-Jakob disease in the United Kingdom: analysis of epidemiological surveillance data for 1970-96
1997
Iatrogenic Creutzfeldt-Jakob Disease, Final Assessment
2012
PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism
2009
Cerebrospinal fluid studies in normal cows and cases of bovine spongiform encephalopathy
1990
Molecular assessment of the potential transmissibilities of BSE and scrapie to humans
1997 Nature
Neuropathological phenotype and ‘prion protein’ genotype correlation in sporadic Creutzfeldt-Jakob disease
1994
Acquired prion disease: iatrogenic CJD, variant CJD, kuru
2003
Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene
1996
A new variant of Creutzfeldt-Jakob disease in the UK
1996 Standout
Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent
1997 StandoutNature
Creutzfeldt–Jakob disease and blood transfusion: results of the UK Transfusion Medicine Epidemiological Review study
2006
Intracerebral distribution of infectious amyloid protein in spongiform encephalopathy
1995 Nobel
Estimation of Epidemic Size and Incubation Time Based on Age Characteristics of vCJD in the United Kingdom
2001 Science
Creutzfeldt-Jakob disease in England and Wales, 1980-1984: a case-control study of potential risk factors.
1988
Abbreviated incubation times for human prions in mice expressing a chimeric mouse–human prion protein transgene
2003 Nobel
A retrospective study of Creutzfeldt-Jakob disease in England and Wales 1970-79. I: Clinical features.
1984
Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
2001
Inherited Creutzfeldt-Jakob disease in a British family associated with a novel 144 base pair insertion of the prion protein gene.
1995
Geographical distribution of cases of Creutzfeldt-Jakob disease in England and Wales 1970-84.
1990
Iatrogenic Creutzfeldt–Jakob disease at the millennium
2000
Evidence for case-to-case transmission of Creutzfeldt-Jakob disease
1982
Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans
1999 Nobel
Iatrogenic Creutzfeldt‐Jakob disease
1994 Nobel
The spongiform encephalopathies.
1991