Standout Papers
Citation Impact
Citing Papers
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
2006 StandoutScienceNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
Dense Core Vesicle Dynamics in Caenorhabditis elegans Neurons and the Role of Kinesin UNC‐104
2004
Single-molecule mechanics of heavy meromyosin and S1 interacting with rabbit or Drosophila actins using optical tweezers.
1995
Nanomotor rotates microscale objects
2006 StandoutNatureNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
Unbinding force of a single motor molecule of muscle measured using optical tweezers
1995 Nature
Bead movement by single kinesin molecules studied with optical tweezers
1990 Nature
Grabbing the cat by the tail: manipulating molecules one by one
2000
Force and velocity measured for single kinesin molecules
1994
Sliding distance between actin and myosin filaments per ATP molecule hydrolysed in skinned muscle fibres
1991 Nature
The myosin swinging cross-bridge model
2001
Nanometres and piconewtons: the macromolecular mechanics of kinesin
1995
Pulling springs to tune transduction: Adaptation by hair cells
1994
DNA Nanodevices
2005
A DNA-fuelled molecular machine made of DNA
2000 StandoutNature
Single photons on demand from a single molecule at room temperature
2000 StandoutNatureNobel
Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers
2008
Unidirectional molecular motor on a gold surface
2005 StandoutNatureNobel
Light-driven monodirectional molecular rotor
1999 StandoutNatureNobel
Synthetic Molecular Motors and Mechanical Machines
2006 Standout
Direct observation of base-pair stepping by RNA polymerase
2005 Nature
Hidden complexity in the mechanical properties of titin
2003 Nature
The Movement of Kinesin Along Microtubules
1996
Force generation of organelle transport measured in vivo by an infrared laser trap
1990 StandoutNatureNobel
A Proton‐Fuelled DNA Nanomachine
2003
The force exerted by a single kinesin molecule against a viscous load
1994
Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution
1995 Nature
Quantized velocities at low myosin densities in an in vitro motility
1991 Nature
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
1993 Standout
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
On/off blinking and switching behaviour of single molecules of green fluorescent protein
1997 StandoutNatureNobel
Passive All-Optical Force Clamp for High-Resolution Laser Trapping
2005
Structural and energetic basis of folded-protein transport by the FimD usher
2013 StandoutNatureNobel
DNA Fuel for Free-Running Nanomachines
2003
The coming of age of de novo protein design
2016 StandoutNatureNobel
A single myosin head moves along an actin filament with regular steps of 5.3 nanometres
1999 Nature
Biological Applications of Optical Forces
1994
Mechanical properties of neuronal growth cone membranes studied by tether formation with laser optical tweezers
1995
GroEL-Mediated Protein Folding: Making the Impossible, Possible
2006
Mechanochemical coupling of the motion of molecular motors to ATP hydrolysis
1996
Sub-piconewton force fluctuations of actomyosin in vitro
1991 Nature
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy
2008 Standout
Electrically driven directional motion of a four-wheeled molecule on a metal surface
2011 StandoutNatureNobel
Force spectroscopy with single bio-molecules
2000
Bioinspired laser-operated molecular locomotive
2004
Micromanipulation of statoliths in gravity-sensing Chara rhizoids by optical tweezers
1995
Direct observation of the rotation of F1-ATPase
1997 StandoutNature
DNA Gyrase: Structure and Function
1991
Molecular Machines Working on Surfaces and at Interfaces
2007
The binding change mechanism for ATP synthase — Some probabilities and possibilities
1993 StandoutNobel
Myosin step size
1990
Structure of the actin-myosin complex and its implications for muscle contraction
1993 Science
Nano-manipulation of actomyosin molecular motors in vitro: a new working principle
1993
Tying a molecular knot with optical tweezers
1999 Nature
Kinesin Motor Mechanics: Binding, Stepping, Tracking, Gating, and Limping
2007
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
A Light‐Stimulated Molecular Switch Driven by Radical–Radical Interactions in Water
2011 StandoutNobel
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
DNA nanomachines
2007
The motor protein myosin-I produces its working stroke in two steps
1999 Nature
Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay
1990
A Free‐Running DNA Motor Powered by a Nicking Enzyme
2005
Dynamics of the Upper 50-kDa Domain of Myosin V Examined with Fluorescence Resonance Energy Transfer
2005 StandoutNobel
Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting
2010
Molecular motors: structural adaptations to cellular functions
1997 Nature
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
Myosin step size: Estimates from motility assays and shortening muscle
1992
Kinesin: walking, crawling or sliding along?
2005
Direct observation of kinesin stepping by optical trapping interferometry
1993 StandoutNature
A Single-Molecule Study of RNA Catalysis and Folding
2000 ScienceNobel
A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy
2005 StandoutScienceNobel
Imaging and Time-Resolved Spectroscopy of Single Molecules at an Interface
1996 StandoutScienceNobel
Rectified motion of a mercury drop in an asymmetric structure
1996
Movement of myosin-coated fluorescent beads on actin cables in vitro
1983 Nature
Structural and Functional Aspects of Domain Motions in Proteins
1984 StandoutNobel
Differential detection of dual traps improves the spatial resolution of optical tweezers
2006
Brownian motors: noisy transport far from equilibrium
2002 Standout
Chemical and Biochemical Analysis Using Scanning Force Microscopy
1999
Flexural rigidity of microtubules measured with the use of optical tweezers
1996
Antibody–antigen flexibility
1987 StandoutNatureNobel
Three-Dimensional Imaging of Single Molecules Solvated in Pores of Poly(acrylamide) Gels
1996 StandoutScienceNobel
Electrical or Photocontrol of the Rotary Motion of a Metallacarborane
2004 Science
Second Generation Light-Driven Molecular Motors. Unidirectional Rotation Controlled by a Single Stereogenic Center with Near-Perfect Photoequilibria and Acceleration of the Speed of Rotation by Structural Modification
2002 StandoutNobel
Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin.
1994
Transcription Against an Applied Force
1995 Science
Mechanical Rotation of the c Subunit Oligomer in ATP Synthase (F 0 F 1 ): Direct Observation
1999 Science
Development of photoresponsive supramolecular machines inspired by biological molecular systems
2012
Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2
1985 StandoutNatureNobel
Molecular Machines
1998 StandoutNobel
The Way Things Move: Looking Under the Hood of Molecular Motor Proteins
2000 Science
Bacteria Swim by Rotating their Flagellar Filaments
1973 Nature
Modeling molecular motors
1997
Calcium‐activated force responses in fast‐ and slow‐twitch skinned muscle fibres of the rat at different temperatures.
1981
How fixed is the differentiated state?
1989
The Tumbleweed: Towards a synthetic protein motor
2009
Origin of nanomechanical cantilever motion generated from biomolecular interactions
2001
The Mechanism of Muscle Contractio
1986
Tensegrity II. How structural networks influence cellular information processing networks
2003
Optical Methods in Cell Physiology
1997
Artificial Molecular Machines
2000 StandoutNobel
Thermodynamics and Kinetics of a Brownian Motor
1997 Science
Rotaxanes Incorporating Two Different Coordinating Units in Their Thread: Synthesis and Electrochemically and Photochemically Induced Molecular Motions
1999 StandoutNobel
Stretching of a Single Tethered Polymer in a Uniform Flow
1995 StandoutScienceNobel
Calcium release by noradrenaline from central sarcoplasmic reticulum in rabbit main pulmonary artery smooth muscle.
1985
Illuminating Single Molecules in Condensed Matter
1999 StandoutScienceNobel
Torsional rigidity of single actin filaments and actin–actin bond breaking force under torsion measured directly by in vitro micromanipulation
1996
Linear Artificial Molecular Muscles
2005 StandoutNobel
Toward Intelligent Molecular Machines: Directed Motions of Biological and Artificial Molecules and Assemblies
2005
Artificial Molecular Machines
2015 Standout
Syntheses and Dynamics of Donor−Acceptor [2]Catenanes in Water
2010 StandoutNobel
Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM
1997 StandoutScience
Optical trapping and manipulation of neutral particles using lasers
1997 StandoutNobel
Docking in Metal-Organic Frameworks
2009 StandoutScienceNobel
Fluctuation analysis of motor protein movement and single enzyme kinetics.
1994
A Dozen Years of Single-Molecule Spectroscopy in Physics, Chemistry, and Biophysics
2002 StandoutNobel
Optical trapping
2004 Standout
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Structural and Functional Insights into the Myosin Motor Mechanism
2010
Knotted Fishing Line, Covalent Bonds, and Breaking Points
1999 StandoutScienceNobel
In control of molecular motion
2000 StandoutNatureNobel
Sliding distance of actin filament induced by a myosin crossbridge during one ATP hydrolysis cycle
1985 Nature
Optical Thermal Ratchet
1995
A Molecular Elevator
2004 StandoutScienceNobel
The force-velocity relationship for microtubule sliding in demembranated sperm flagella of the sea urchin.
1988
Methods of single-molecule fluorescence spectroscopy and microscopy
2003 StandoutNobel
Fluorescence Spectroscopy of Single Biomolecules
1999 StandoutScience
Stochastic action of actomyosin motor
2004
Electronically Configurable Molecular-Based Logic Gates
1999 StandoutScienceNobel
Functional Hydrogel Surfaces: Binding Kinesin‐Based Molecular Motor Proteins to Selected Patterned Sites
2005
The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay.
1990
Generalized Efficiency and its Application to Microscopic Engines
1999
Works of Robert Simmons being referenced
Single myosin molecule mechanics: piconewton forces and nanometre steps
1994 Nature
Glasperlenspiel II
1993
Models of Motor-Assisted Transport of Intracellular Particles
2001
Chapter 1 In Vitro Methods for Measuring Force and Velocity of the Actin-Myosin Interaction Using Purified Proteins
1993 StandoutNobel
Testing time for muscle
1992
Elasticity and unfolding of single molecules of the giant muscle protein titin
1997 Nature
The Elasticity of Single Titin Molecules Using a Two-Bead Optical Tweezers Assay
2004
The structure of the rigor complex and its implications for the power stroke
2004
Molecular motors: Single-molecule mechanics
1996
Tension transients during the rise of tetanic tension in frog muscle fibres.
1986
Proposed Mechanism of Force Generation in Striated Muscle
1971 StandoutNature
The dependence of force and shortening velocity on substrate concentration in skinned muscle fibres from Rana temporaria.
1984
Adenosine diphosphate and strain sensitivity in myosin motors
2004
Single-Molecule Biomechanics with Optical Methods
1999 Science
Quantitative measurements of force and displacement using an optical trap
1996 StandoutNobel
The relation between stiffness and filament overlap in stimulated frog muscle fibres.
1981
Tension transients during steady shortening of frog muscle fibres.
1985
Millisecond time-resolved changes in x-ray reflections from contracting muscle during rapid mechanical transients, recorded using synchrotron radiation.
1981
Control of tension development in scallop muscle fibres with foreign regulatory light chains
1980 Nature
Cellular and molecular biology of muscle development
1990
Changes in the X-ray reflections from contracting muscle during rapid mechanical transients and their structural implications
1983
Coupling between phosphate release and force generation in muscle actomyosin
2004
Tension responses to sudden length change in stimulated frog muscle fibres near slack length
1977
Definitions of free energy levels in biochemical reactions
1976 Nature
The motor mechanism of myosin V: insights for muscle contraction
2004
Control of sarcomere length in skinned muscle fibres of Rana temporaria during mechanical transients.
1984