Citation Impact
Citing Papers
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
Impaired CD4 and CD8 Effector Function and Decreased Memory T Cell Populations in ICOS-Deficient Patients
2009
ICOS Mediates the Development of Insulin-Dependent Diabetes Mellitus in Nonobese Diabetic Mice
2008
The Role of ICOS in Directing T Cell Responses: ICOS-Dependent Induction of T Cell Anergy by Tolerogenic Dendritic Cells
2009
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
ICOS is critical for T helper cell–mediated lung mucosal inflammatory responses
2001
Monocyte recruitment during infection and inflammation
2011 Standout
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
2015 Standout
The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells
2007
New regulatory co-receptors: inducible co-stimulator and PD-1
2002 StandoutNobel
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
The Roles of the New Negative T Cell Costimulatory Pathways in Regulating Autoimmunity
2004
Expression of Chemokine Receptors CCR1 and CCR5 Reflects Differential Activation of Mononuclear Phagocytes in Pattern II and Pattern III Multiple Sclerosis Lesions
2004
T Helper Cell-specific Regulation of Inducible Costimulator Expression via Distinct Mechanisms Mediated by T-bet and GATA-3
2007
Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis
2003
Negative co-receptors on lymphocytes
2002
Chemokines as regulators of T cell differentiation
2001
Cytokines and Chemokines as Mediators of Protection and Injury in the Central Nervous System Assessed in Transgenic Mice
2002
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Chemokines and disease
2001
Co‐stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamily
2005 StandoutNobel
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
2016 StandoutNobel
CCR1+/CCR5+ Mononuclear Phagocytes Accumulate in the Central Nervous System of Patients with Multiple Sclerosis
2001
Regulation of Mouse Inducible Costimulator (ICOS) Expression by Fyn-NFATc2 and ERK Signaling in T Cells
2006
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
ICOS Deficiency Results in Exacerbated IL-17 Mediated Experimental Autoimmune Encephalomyelitis
2009
The immunological synapse for B-cell memory: the role of the ICOS and its ligand for the longevity of humoral immunity
2003
Asthma: an epidemic of dysregulated immunity
2002
The B7/CD28 costimulatory family in autoimmunity
2005
Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections
2003
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell–dependent B cell responses
2003
Three or more routes for leukocyte migration into the central nervous system
2003
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Interaction Between ICOS-B7RP1 and B7-CD28 Costimulatory Pathways in Alloimmune Responses In Vivo
2003
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases
2004
Targeted deletion of CX3CR1 reveals a role for fractalkine in cardiac allograft rejection
2001
T‐cell costimulatory pathways in allograft rejection and tolerance
2003
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
2009
Extracellular mRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-α Secretion and Signaling through a Nucleotide Receptor
2002 StandoutNobel
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice
2003 StandoutNobel
Regulation of Experimental Autoimmune Encephalomyelitis by Chemokines and Chemokine Receptors
2002
The role of ICOS and other costimulatory molecules in allergy and asthma
2004
Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis
2004
Mechanisms of H4/ICOS costimulation: effects on proximal TCR signals and MAP kinase pathways
2002
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS)
2010 StandoutNobel
The B7–CD28 superfamily
2002
An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System
2005 Standout
Role of ICOS versus CD28 in antiviral immunity
2002
The right place at the right time: novel B7 family members regulate effector T cell responses
2002
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
2018 Standout
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
The ICOS Molecule Plays a Crucial Role in the Development of Mucosal Tolerance
2005
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency
2009
PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
2003 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Molecular Characterization of Human 4Ig-B7-H3, a Member of the B7 Family with Four Ig-Like Domains
2004
Key multiplicity issues in clinical drug development
2012
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
2014
Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy
2014 StandoutNobel
A Role for Inducible Costimulator Protein in the CD28- Independent Mechanism of Resistance to Toxoplasma gondii
2002
Cutting Edge: Inducible Costimulator Protein Regulates Both Th1 and Th2 Responses to Cutaneous Leishmaniasis
2002
CD4+CD25+ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion
2004
Role for IL-10 in Suppression Mediated by Peptide-Induced Regulatory T Cells In Vivo
2003
THE B7 FAMILY REVISITED
2005 Standout
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
IMMUNOLOGY OF MULTIPLE SCLEROSIS
2005 Standout
Inducible Costimulator Protein Controls the Protective T Cell Response Against Listeria monocytogenes
2002
Molecular Modeling and Functional Mapping of B7-H1 and B7-DC Uncouple Costimulatory Function from PD-1 Interaction
2003 StandoutNobel
The Diabetes Susceptibility Locus Idd5.1 on Mouse Chromosome 1 Regulates ICOS Expression and Modulates Murine Experimental Autoimmune Encephalomyelitis
2004
Ligand Binding Sites of Inducible Costimulator and High Avidity Mutants with Improved Function
2002
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+T cells
2002
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
ICOS-Mediated Costimulation on Th2 Differentiation Is Achieved by the Enhancement of IL-4 Receptor-Mediated Signaling
2005
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
ICOS Expression by Activated Human Th Cells Is Enhanced by IL-12 and IL-23: Increased ICOS Expression Enhances the Effector Function of Both Th1 and Th2 Cells
2004
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses
2002
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
2007 StandoutNobel
Critical Role of the Programmed Death-1 (PD-1) Pathway in Regulation of Experimental Autoimmune Encephalomyelitis
2003
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
2005 Standout
ICOS Controls Effector Function but Not Trafficking Receptor Expression of Kidney-Infiltrating Effector T Cells in Murine Lupus
2009
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b −/− Pdcd1 −/− mice
2005 StandoutNobel
Investigating chemokines and chemokine receptors in patients with multiple sclerosis: opportunities and challenges.
2001
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Inducible Costimulatory Molecule-B7-Related Protein 1 Interactions Are Important for the Clonal Expansion and B Cell Helper Functions of Naive, Th1, and Th2 T Cells
2003
Amelioration of Collagen-Induced Arthritis by Blockade of Inducible Costimulator-B7 Homologous Protein Costimulation
2002
Expression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10
2003
Programmed Death-1 Targeting Can Promote Allograft Survival
2002
Disruption of the ICOS-B7RP-1 Costimulatory Pathway Leads to Enhanced Hepatic Immunopathology and Increased Gamma Interferon Production by CD4 T Cells in Murine Schistosomiasis
2003
Works of Robert Silva being referenced
The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
2001
Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent
2000
Lurasidone in the Treatment of Schizophrenia: A Randomized, Double-Blind, Placebo- and Olanzapine-Controlled Study
2011