Citation Impact
Citing Papers
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Alzheimer Precursor Protein Interaction with the Nogo-66 Receptor Reduces Amyloid-β Plaque Deposition
2006
Calcium and mitochondria: mechanisms and functions of a troubled relationship
2004
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
2007
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
2002 StandoutNature
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1
2007 StandoutNobel
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
Mitochondrial permeability transitions: how many doors to the house?
2004
Amyloid β protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes
1998
Protein Kinase Inhibitor H7 Blocks the Induction of Immediate-Early Genes zif268 and c-fosby a Mechanism Unrelated to Inhibition of Protein Kinase C but Possibly Related to Inhibition of Phosphorylation of RNA Polymerase II
1999
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Mitochondrial creatine kinase in human health and disease
2005
Ca2+-dependent Control of the Permeability Properties of the Mitochondrial Outer Membrane and Voltage-dependent Anion-selective Channel (VDAC)
2006
What is the mitochondrial permeability transition pore?
2009
The voltage-dependent anion channel-1 modulates apoptotic cell death
2005
Amyloid β‐peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease
2004
Carboxylic Acid (Bio)Isosteres in Drug Design
2013
Neurotrophins and their receptors: A convergence point for many signalling pathways
2003 Standout
Neurotrophins as synaptic modulators
2001 Standout
Interpretation of BMP signaling in early Xenopus development
2007 StandoutNobel
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
The role of mitochondria in protection of the heart by preconditioning
2007
Alzheimer Presenilin-1 Mutations Dramatically Reduce Trimming of Long Amyloid β-Peptides (Aβ) by γ-Secretase to Increase 42-to-40-Residue Aβ
2014
NMR studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two Alzheimer peptides with widely different plaque‐competence, Aβ(1–40)ox and Aβ(1–42)ox
2001 StandoutNobel
Protein aggregation and neurodegenerative disease
2004 Standout
Benefits from Dietary Polyphenols for Brain Aging and Alzheimer’s Disease
2008
Neurophysiologic studies in congenital insensitivity to pain with anhidrosis
2001
Axonal transport and neuronal transcytosis of trophic factors, tracers, and pathogens
2003
Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR
2003
The mitochondrial permeability transition fromin vitroartifact to disease target
2006
Nerve growth factor stimulates in vitro invasive capacity of DU145 human prostatic cancer cells
1997
On the Role of VDAC in Apoptosis: Fact and Fiction
2005
Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells
1994
Nanoparticle-assisted optical tethering of endosomes reveals the cooperative function of dyneins in retrograde axonal transport
2015 StandoutNobel
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
Plant Polyphenols as Dietary Antioxidants in Human Health and Disease
2009 Standout
The neurotrophin receptor p75NTR: novel functions and implications for diseases of the nervous system
2002
Alzheimer's disease
2006 Standout
Alzheimer's disease
2016 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The Toxicity of the Alzheimer's β-Amyloid Peptide Correlates with a Distinct Fiber Morphology
1997
Increased p75NTR Expression in Hippocampal Neurons Containing Hyperphosphorylated τ in Alzheimer Patients
2002
Activation of apoptosis signalling pathways by reactive oxygen species
2016 Standout
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Alzheimer's disease and Aβ toxicity: from top to bottom
2001
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
The Amyloid State of Proteins in Human Diseases
2012 Standout
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Properties of the permeability transition in VDAC1−/− mitochondria
2006
The role of the mitochondrial permeability transition pore in heart disease
2009
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
The BCL-2 protein family: opposing activities that mediate cell death
2007 Standout
Reactive oxygen species, cellular redox systems, and apoptosis
2010 Standout
The cholinergic system in aging and neuronal degeneration
2010
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Structure and function of γ-secretase
2008
Nucleation-Dependent Polymerization Is an Essential Component of Amyloid-Mediated Neuronal Cell Death
2005
Chemical modulators working at pharmacological interface of target proteins
2011
Perineural invasion in cancer
2009 Standout
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Endocytosis of Activated TrkA: Evidence that Nerve Growth Factor Induces Formation of Signaling Endosomes
1996
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Brain Repair
2007
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.
1994
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
3D structure of Alzheimer's amyloid-β(1–42) fibrils
2005 Standout
Tumor Necrosis Factor Death Receptor Signaling Cascade Is Required for Amyloid-β Protein-Induced Neuron Death
2004
Expression of TrkA confers neuron-like responsiveness to nerve growth factor on an immortalized hypothalamic cell line.
1994
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection
2010
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Strategien zur Modulation von Protein‐Protein‐Wechselwirkungen mit synthetischen Substanzen
2005
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Neurotrophins and Neuronal Plasticity
1995 StandoutScience
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
1997 StandoutNobel
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Neurotrophin-regulated signalling pathways
2006 Standout
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
2012
Cancer Genome Landscapes
2013 StandoutScience
Mitochondria as Functional Targets of Proteins Coded by Human Tumor Viruses
2005
The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease
2018 Standout
An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions
2015 StandoutNobel
Deracemizing α‐Branched Carboxylic Acids by Catalytic Asymmetric Protonation of Bis‐Silyl Ketene Acetals with Water or Methanol
2019 StandoutNobel
Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.
1993
Self-Assembly of β-Amyloid 42 Is Retarded by Small Molecular Ligands at the Stage of Structural Intermediates
2000 StandoutNobel
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
The Role of Mitochondria in Apoptosis
2009 Standout
Works of Robert Schubenel being referenced
Nerve growth factor-induced loss of cell-associated nerve growth factor receptor in human melanoma A875 cells
1992
?-amyloid binds to p75NTRand activates NF?B in human neuroblastoma cells
1998
NSAID-derived γ-secretase modulation requires an acidic moiety on the carbazole scaffold
2011
β‐Amyloid‐Induced Cell Toxicity: Enhancement of 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide‐Dependent Cell Death
1996
The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore
2003
NGF ligand alters NGF signaling via p75NTR and TrkA
2000
Independent Generation of Aβ42 and Aβ38 Peptide Species by γ-Secretase
2008
Protein Kinase Inhibitor H‐7 Differentially Affects Early and Delayed Nerve Growth Factor Responses in PC12 Cells
1994
Multiple trkA proteins in PC12 cells bind NGF with a slow association rate.
1992