Citation Impact
Citing Papers
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
DNA loops induced by cooperative binding of λ repressor
1986 Nature
3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy
2006 StandoutNobel
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
1985 StandoutNatureNobel
Assembly and self-association of Oxytricha telomeric nucleoprotein complexes
1989 StandoutNobel
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome
1993 StandoutNatureNobel
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Specific regulation of gene expression by antisense, sense and antigene nucleic acids
1990
The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
1989 StandoutNatureNobel
DNA Looping and Physical Constraints on Transcription Regulation
2003
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
1997
DNA supercoiling promotes formation of a bent repression loop in lac DNA
1987
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Structural studies of protein–nucleic acid interaction: the sources of sequence-specific binding
1990 StandoutNobel
Next generation vaccines and vectors: Designing downstream processes for recombinant protein‐based virus‐like particles
2015
Design of gene circuits: lessons from bacteria
2004
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Cooperativity mutants of the γδ resolvase identify an essential interdimer interaction
1990 StandoutNobel
A zonal organization of odorant receptor gene expression in the olfactory epithelium
1993 StandoutNobel
Interaction at a distance between λrepressers disrupts gene activation
1988 Nature
The immune response of Drosophila
2003 StandoutNatureNobel
Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements
1987
Emergence of vancomycin tolerance in Streptococcus pneumoniae
1999 StandoutNatureNobel
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Specific destruction of the second lac operator decreases repression of the lac operon in Escherichia coli fivefold
1987
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Sequence-selective DNA recognition by synthetic ligands
1991
Stringent spacing requirements for transcription activation by CRP
1990
Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium
1994
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
The 43 residue DNA binding domain of γδ resolvase binds adjacent major and minor grooves of DNA
1989
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
1990 StandoutNatureNobel
Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein
1988
Evolution of protein function by Domain swapping
2001
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site
1990
Cyclic adenosine 5'-monophosphate in Escherichia coli
1976
Identification of a telomere-binding activity from yeast.
1986
A Physical Map of the Escherichia coli K12 Genome
1987 Science
The three operators of the lac operon cooperate in repression.
1990
Influence of supercoiling and sequence context on operator DNA binding with lac repressor.
1987
On the different binding affinities of CRP at thelac, galandmalT promoter regions
1983
The structure of bacteriophage T7 lysozyme, a zinc amidase and an inhibitor of T7 RNA polymerase.
1994
The helix-turn-helix DNA binding motif
1989
Detecting Subtle Sequence Signals: a Gibbs Sampling Strategy for Multiple Alignment
1993 Science
P22 repressor mutants deficient in co-operative binding and DNA loop formation.
1989
Cyclic AMP Receptor Protein: Role in Transcription Activation
1984 Science
Molecular basis of base substitution hotspots in Escherichia coli
1978 StandoutNatureNobel
The gamma delta resolvase bends the res site into a recombinogenic complex.
1988
Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning
1977 StandoutScienceNobel
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
A model for the non-specific binding of catabolite gene activator protein to DNA
1984 StandoutNobel
Purification of and Properties of the Cyclic Adenosine 3',5'-Monophosphate Receptor Protein which Mediates Cyclic Adenosine 3',5'-Monophosphate-dependent Gene Transcription in Escherichia coli
1971
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 gene
1987
A functional analysis of the rel gene in Escherichia coli
1969
Structure, sequence and expression of the hepatitis delta (δ) viral genome
1986 StandoutNatureNobel
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding
1982 StandoutNatureNobel
Analysis of gene control signals by DNA fusion and cloning in Escherichia coli
1980 Standout
Structure of catabolite gene activator protein at 2.9 Å resolution suggests binding to left-handed B-DNA
1981 StandoutNatureNobel
The cAMP-binding domains of the regulatory subunit of cAMP-dependent protein kinase and the catabolite gene activator protein are homologous.
1982 StandoutNobel
Filter replicas and permanent collections of recombinant DNA plasmids
1979
Long-range cooperativity between gene regulatory sequences in a prokaryote
1987 Nature
Molecular Biology of Learning: Modulation of Transmitter Release
1982 StandoutScienceNobel
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.
1988 StandoutNobel
Identification of a contact between arginine-180 of the catabolite gene activator protein (CAP) and base pair 5 of the DNA site in the CAP-DNA complex.
1990
Cloning and sequence of the crp gene of Escherichia coli K 12
1982
Molecular cloning of Ancient Egyptian mummy DNA
1985 StandoutNatureNobel
Analysis of Endonuclease R· Eco RI Fragments of DNA from Lambdoid Bacteriophages and Other Viruses by Agarose-Gel Electrophoresis
1974
Two DNA-Binding Factors Recognize Specific Sequences at Silencers, Upstream Activating Sequences, Autonomously Replicating Sequences, and Telomeres in Saccharomyces cerevisiae
1988 StandoutNobel
Facilitated Target Location in Biological Systems
1989
Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide
1991 StandoutScience
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
1986 StandoutNobel
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.
1987
DNA looping in cellular repression of transcription of the galactose operon.
1990
Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP.
1982 StandoutNobel
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.
1988 StandoutNobel
MSI and MSII made on Ribosome in Idling Step of Protein Synthesis
1972 StandoutNatureNobel
Interaction site of Escherichia coli cyclic AMP receptor protein on DNA of galactose operon promoters.
1979
Adenosine 3′:5′-Cyclic Monophosphate Control of the Enzymes of Glutamine Metabolism in Escherichia coli
1972 StandoutNobel
Lac DNA, RNA Polymerase and Cyclic AMP Receptor Protein, Cyclic AMP, Lac Repressor and Inducer are the Essential Elements for Controlled Lac Transcription
1971
Multiple DNA-pRotein Interactions Governing High-Precision DNA Transactions
1986 Science
Specific small nuclear RNAs are associated with yeast spliceosomes
1986 StandoutNobel
On the Regulation of Guanosine Tetraphosphate Levels in Stringent and Relaxed Strains of Escherichia coli
1971
Genetic studies of the lac repressor
1977
Selection of DNA binding sites by regulatory proteins
1987
lac repressor forms loops with linear DNA carrying two suitably spaced lac operators.
1987
The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA.
1988
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Protein-induced bending and DNA cyclization.
1992
The chromosomal distribution of mouse odorant receptor genes.
1996 StandoutNobel
DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1.
1991
Analysis of gamma delta resolvase mutants in vitro: evidence for an interaction between serine-10 of resolvase and site I of res.
1986
Cell-type-specific contacts to immunoglobulin enhancers in nuclei
1985 StandoutNatureNobel
Combinatorial structure of a body muscle-specific transcriptional enhancer in Caenorhabditis elegans.
1994 StandoutNobel
CTCF, a Conserved Nuclear Factor Required for Optimal Transcriptional Activity of the Chicken c-myc Gene, Is an 11-Zn-Finger Protein Differentially Expressed in Multiple Forms
1993
λ Repressor and cro—components of an efficient molecular switch
1981 Nature
Structure and function of telomeres
1991 StandoutNatureNobel
Gene regulation by proteins acting nearby and at a distance
1986 Nature
Protein-protein interactions directing resolvase site-specific recombination: a structure-function analysis.
1993 StandoutNobel
Molecular cloning and nucleotide sequencing of the gene for E. coli cAMP receptor protein
1982
The use of synthetic oligodeoxyribonucleotides to produce specific deletions in the araBAD promoter of Escherichia coli B/r
1982
Interaction Between Transcription Regulatory Regions of Prolactin Chromatin
1993 Science
Control of gene expression in bacteriophage P22 by a small antisense RNA. I. Characterization in vitro of the Psar promoter and the sar RNA transcript.
1987
The change of DNA structure by specific binding of the cAMP receptor protein from rotation diffusion and dichroism measurements.
1984
Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination.
1990
Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli
1984 Nature
DNA-looping and enhancer activity: association between DNA-bound NtrC activator and RNA polymerase at the bacterial glnA promoter.
1990
Sigma factors fromE. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins
1986
Works of Robert Schleif being referenced
24 Regulation of the L-Arabinose Catabolic Operon araBAD
1992
Paucity of sites mutable to constitutivity in the araC activator gene of the l-arabinose operon of Escherichia coli
1975
Determining residue-base interactions between AraC protein and araI DNA
1989
Reaching Out
1994
Isolation and physical characterization of random insertions in staphylococcal nuclease
1998
Modeling and Studying Proteins with Molecular Dynamics
2004
AraC-DNA looping: Orientation and distance-dependent loop breaking by the cyclic AMP receptor protein
1991
AraC Protein Can Activate Transcription from Only One Position and When Pointed in Only One Direction
1993
Size fractionation of double-stranded DNA by precipitation with polyethylene glycol
1975
Arabinose C Protein: Regulation of the Arabinose Operon in vitro
1971
The araE low affinity l-arabinose transport promoter
1983
The DNA loop model for ara repression: AraC protein occupies the proposed loop sites in vivo and repression-negative mutations lie in these same sites.
1986
In vivo regulation of the Escherichia coli araC promoter
1983
An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression.
1984
Altered DNA contacts made by a mutant AraC protein
1985
A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.
1985
DNA Looping
1988 Science
Is the amino acid but not the nucleotide sequence of the Escherichia coli araC gene conserved?
1982
Dual control of arabinose genes on transducing phage λdara
1971
Different cyclic AMP requirements for induction of the arabinose and lactose operons of Escherichia coli
1973
The Escherichia coli L-arabinose operon: binding sites of the regulatory proteins and a mechanism of positive and negative regulation.
1980
DNA LOOPING
1992
Missing contact probing of DNA-protein interactions.
1987
Transcription of Escherichia coli ara in vitro
1986
Reaching Out Locating and Lengthening the Interdomain Linker in AraC Protein
1994
Upstream repression and CRP stimulation of the Escherichia colil-arabinose operon
1984
Why should DNA loop?
1987 Nature
Variation of half-site organization and DNA looping by AraC protein.
1993
High resolution electron microscopic studies of genetic regulation
1976
The araC promoter: Transcription, mapping and interaction with the araBAD promoter
1977
Origin of chloramphenicol particle protein
1968
Regulation of the Escherichia coli l-arabinose operon studied by gel electrophoresis DNA binding assay
1984
Factor Necessary for Ribosomal RNA Synthesis
1970 Nature
DNA Binding by Proteins
1988 Science
Nucleotide sequence of the L-arabinose regulatory region of Escherichia coli K12.
1978
A Regulatory Cascade in the Induction of rhaBAD
1993
Control of production of ribosomal protein
1967