Standout Papers
Citation Impact
Citing Papers
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Talin determines the nanoscale architecture of focal adhesions
2015
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes
2007 StandoutNobel
Roles of Cardiac Transcription Factors in Cardiac Hypertrophy
2003
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Focal Adhesion Kinase Signaling Regulates Cardiogenesis of Embryonic Stem Cells
2005
Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.
1995
Cardiac fibroblasts: friend or foe?
2006
Talins and kindlins: partners in integrin-mediated adhesion
2013
Visualizing Gene Expression in Living Mammals Using a Bioluminescent Reporter
1997
A Role for Focal Adhesion Kinase in Phenylephrine-induced Hypertrophy of Rat Ventricular Cardiomyocytes
2000
The role of the Grb2–p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis
2003
Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse
2016
Transgenic Mice with Cardiac Overexpression of α1B-Adrenergic Receptors
1997 StandoutNobel
Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions
2015
Direct Activation of a GATA6 Cardiac Enhancer by Nkx2.5: Evidence for a Reinforcing Regulatory Network of Nkx2.5 and GATA Transcription Factors in the Developing Heart
2000
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Pathways of matrix metalloproteinase induction in heart failure: Bioactive molecules and transcriptional regulation
2006
Calcium–calcineurin signaling in the regulation of cardiac hypertrophy
2004
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Integrins as “functional hubs” in the regulation of pathological angiogenesis
2009
Odorant Receptors Govern the Formation of a Precise Topographic Map
1998 StandoutNobel
Partial rescue of defects in Cited2-deficient embryos by HIF-1α heterozygosity
2006 StandoutNobel
Myocardial β-adrenergic receptor signaling in vivo: insights from transgenic mice
1996 StandoutNobel
Genes and physiology: molecular physiology in genetically engineered animals.
1996
A lethal perinatal cardiac phenotype resulting from altered integrin function in cardiomyocytes
2002
Atherosclerosis — An Inflammatory Disease
1999 Standout
Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
2010 Standout
Self-assembled microdevices driven by muscle
2005
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Calcineurin?NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs
2004
Ventricular Expression of a MLC-2v-ras Fusion Gene Induces Cardiac Hypertrophy and Selective Diastolic Dysfunction in Transgenic Mice
1995
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload
1999
Melusin, a muscle-specific integrin β1–interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
2002
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice
2005
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
The structure and regulation of vinculin
2006
Regulation of Integrin Activation
2011
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
2017 StandoutNobel
Raf-1 Kinase Is Required for Cardiac Hypertrophy and Cardiomyocyte Survival in Response to Pressure Overload
2004
Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
1998 StandoutNobel
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Structure and polymorphism of the mouse prion protein gene.
1994 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Retinoid-dependent pathways suppress myocardial cell hypertrophy.
1995
Signaling in Myocardial Hypertrophy
1999
Development, Maturation, and Transdifferentiation of Cardiac Sympathetic Nerves
2012
Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy.
1995
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.
1995 StandoutNobel
Myocyte-Restricted Focal Adhesion Kinase Deletion Attenuates Pressure Overload–Induced Hypertrophy
2006
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
1993
Overexpression of angiotensin AT 1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block
1997 StandoutNobel
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Transthoracic Echocardiography in Models of Cardiac Disease in the Mouse
1996
The Nuclear δB Isoform of Ca2+/Calmodulin-dependent Protein Kinase II Regulates Atrial Natriuretic Factor Gene Expression in Ventricular Myocytes
1997
Matrix Metalloproteinases
2002
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
2006 StandoutNobel
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
2008 Standout
Transgenic Gαq overexpression induces cardiac contractile failure in mice
1997
A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction.
1990
Evaluation of synthetic linear motor-molecule actuation energetics
2006 StandoutNobel
Hypertrophy, Pathology, and Molecular Markers of Cardiac Pathogenesis
1998
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
1996 StandoutNobel
Integrin-mediated mechanotransduction
2016
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.
1996 StandoutNobel
Tensegrity II. How structural networks influence cellular information processing networks
2003
Origin of Cardiac Fibroblasts and the Role of Periostin
2009
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A
1997 StandoutNobel
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis
1994
Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer
1997 StandoutNobel
Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis
2003
Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment
2007 StandoutNobel
Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
2001 StandoutNobel
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
Molecular Advances in Cardiovascular Biology
1993 Science
Cardiac Chamber Formation: Development, Genes, and Evolution
2003
Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.
1994
Direct and Indirect Interactions between Calcineurin-NFAT and MEK1-Extracellular Signal-Regulated Kinase 1/2 Signaling Pathways Regulate Cardiac Gene Expression and Cellular Growth
2005
The MEF-3 Motif is Required for MEF-2-Mediated Skeletal Muscle-Specific Induction of the Rat Aldolase A Gene
1993
Myocardial alpha-thrombin receptor activation induces hypertrophy and increases atrial natriuretic factor gene expression.
1993
Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.
1994 StandoutNobel
Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.
1991
Ligand-induced overexpression of a constitutively active β 2 -adrenergic receptor: Pharmacological creation of a phenotype in transgenic mice
1997 StandoutNobel
Recent progress in understanding apolipoprotein B.
1990
Cardiac-Specific Ablation of G-Protein Receptor Kinase 2 Redefines Its Roles in Heart Development and β-Adrenergic Signaling
2006
HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy.
1993
Microinjection of antibodies and expression vectors into living myocardial cells. Development of a novel approach to identify candidate genes that regulate cardiac growth and hypertrophy.
1992
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.
1995
Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
2000 StandoutNobel
Works of Robert S. Ross being referenced
Heterozygous Inactivation of the Vinculin Gene Predisposes to Stress-Induced Cardiomyopathy
2004
Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance
2001
Spatial distribution of nerve sprouting after myocardial infarction in mice
2006
What is vinculin needed for in platelets?
2010
Talin1 Has Unique Expression versus Talin 2 in the Heart and Modifies the Hypertrophic Response to Pressure Overload
2012
Molecular and mechanical synergy: cross-talk between integrins and growth factor receptors*1
2004
Osteopontin modulates angiotensin II- induced fibrosis in the intact murine heart
2004
Homozygous hypobetalipoproteinemia: a disease distinct from abetalipoproproteinemia at the molecular level.
1988
Cyclosporin A Regulates Sodium‐Calcium Exchanger (NCX1) Gene Expression in Vitro and Cardiac Hypertrophy in NCX1 Transgenic Mice
2002
Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling
2009
Functional Adult Myocardium in the Absence of Na + -Ca 2+ Exchange
2004
Integrins and the Myocardium
2001
Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene.
1992
Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth
2013
A deletion mutation in the ApoC-II gene (ApoC-II Nijmegen) of a patient with a deficiency of apolipoprotein C-II.
1988
β 1 Integrins Participate in the Hypertrophic Response of Rat Ventricular Myocytes
1998
Cardiac Myocyte-Specific Excision of the β1 Integrin Gene Results in Myocardial Fibrosis and Cardiac Failure
2002
1152-201 Brain natriuretic peptide correlates with myocardial performance index in congenital heart disease patients
2004
Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression.
1991
Molecular and physiological alterations in murine ventricular dysfunction.
1994
An HF-1a/ HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and establishes an anterior-posterior gradient of expression
1996
A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light-chain-2 gene confers cardiac-specific and alpha-adrenergic-inducible expression in cultured neonatal rat myocardial cells.
1991
Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling
2007
Striated muscle-specific β1D-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway
2000
Endothelial Expression of Beta‐1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling
2008