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Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice
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A mouse model of familial porphyria cutanea tarda
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Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
Iron and the anemia of chronic disease.
2002
The molecular defect in hypotransferrinemic mice
2000
What Is Responsible for the Initiating Chemistry of Iron-Mediated Lipid Peroxidation: An Update
2007
Hepcidin and iron regulation, 10 years later
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Increased Risk of Acute Myocardial Infarction in Carriers of the Hemochromatosis Gene Cys282Tyr Mutation
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N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-kappaB inhibition.
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Iron Is Hot: An Update on the Pathophysiology of Hemochromatosis
1998
Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor
1992 StandoutScience
Iron Is Hot: An Update on the Pathophysiology of Hemochromatosis
1998
Liver cell models in in vitro toxicology.
1998
Systemic Iron Homeostasis
2013
Juvenile and adult hemochromatosis are distinct genetic disorders.
1998
A mouse model for beta 0-thalassemia.
1995 StandoutNobel
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
2002
Expression of the Na + /Ca 2+ exchanger emerges in hepatic stellate cells after activation in association with liver fibrosis
1998
Hepatic stellate cell activation in genetic haemochromatosis
1997
The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
1998
Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6
2006
Cellular sources of glutathione S-transferase P in primary cultured rat hepatocytes: localization by in situ hybridization
1994
N-Acetyl-l -Cysteine Inhibits Primary Human T Cell Responses at the Dendritic Cell Level: Association with NF-κB Inhibition
1999
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene
2001
Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders
2001
Effect of hepcidin on intestinal iron absorption in mice
2004
Regulation of Iron Metabolism by Hepcidin
2006
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Morphology of liver repair following cholestatic liver injury: resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts Note
2000
Hepatic mitochondrial energy production in rats with chronic iron overload
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Prevention of Hepatocyte Injury and Lipid Peroxidation by Iron Chelators and α–Tocopherol in Isolated Iron–Loaded Rat Hepatocytes
1990
Increased Hepatic Oxidative DNA Damage in Patients with Hepatocellular Carcinoma
2001
Ascorbate‐Stimulated Lipid Peroxidation in Human Brain Is Dependent on Iron but Not on Hydroxyl Radical
1996
Decreased Liver Hepcidin Expression in the Hfe Knockout Mouse
2002
Oxidant injury to hepatic mitochondria in patients with Wilson's disease and Bedlington terriers with copper toxicosis
1994
Repetitive Self-Limited Acute Pancreatitis Induces Pancreatic Fibrogenesis in the Mouse
2000
Determination of hepatic iron concentration in fresh and paraffin-embedded tissue: Diagnostic implications
1994
Hepatic Mitochondrial Malondialdehyde Metabolism in Rats With Chronic Iron Overload
1990
Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury
1999
Metal-Induced Hepatotoxicity
1996
CD14‐positive hepatic monocytes/macrophages increase in hereditary hemochromatosis
2004
Identification and characterization of a receptor for tissue ferritin on activated rat lipocytes.
1994
Global Transcriptional Response to Hfe Deficiency and Dietary Iron Overload in Mouse Liver and Duodenum
2009
Accelerated hepatic fibrosis in patients with combined hereditary hemochromatosis and chronic hepatitis C infection
2002
Increased 4–Hydroxynonenal Levels in Experimental Alcoholic Liver Disease: Association of Lipid Peroxidation With Liver Fibrogenesis
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The Pathology of Hepatic Iron Overload: A Free Radical–Mediated Process?
1990
Molecular aspects of iron absorption and HFE expression
2001
Hereditary hemochromatosis in the post- HFE era
2008
Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract
1997
Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis
2002
Knockout of the mouse HFE gene produces hemochromatosis
1998
Chronic iron overload causes activation of rat lipocytes in vivo
1995
Intracellular Signaling Pathways in Stellate Cell Activation
1999
Gadolinium chloride suppresses hepatic oval cell proliferation in rats with biliary obstruction.
1998
Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with β 2 -microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells
1997
Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis
2003
Pathogenesis of hereditary hemochromatosis: genetics and beyond.
2002
Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum
1999
Lysis of rat liver lysosomes in vitro by Δ9-tetrahydrocannabinol
1974
Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis
1997
Fibronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells
1997
Suppression by antithyroid drugs of experimental hepatic necrosis after ethanol treatment. Effect on thyroid gland or on peripheral deiodination?
1979
Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice
2012
Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis
2001
Thiol regulation of endotoxin-induced release of tumour necrosis factor α from isolated rat Kupffer cells
1996
Effect of vitamin E supplementation on hepatic fibrogenesis in chronic dietary iron overload
1997
Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis
2002
Liver cell enlargement induced by chronic alcohol consumption: studies on its causes and consequences
1982
Role of free radicals in liver diseases and hepatic fibrosis.
1994
Naturally variant autosomal and sex-linked loci determine the severity of iron overload in β2-microglobulin-deficient mice
2001
Vitamin A-poor lipocytes: a novel desmin-negative lipocyte subpopulation, which can be activated to myofibroblasts
1995
Transferrin receptor 2: Continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis
2000
Hepatic alpha-smooth muscle actin expression in hepatitis C patients before and after interferon therapy.
2001
TNF-alpha and IL-6 expression in perfused rat liver after intraportal candidemia vs. E. coli or S. aureus bacteremia
1994
HFE gene knockout produces mouse model of hereditary hemochromatosis
1998
Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1
1999