Standout Papers
Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
Inhibition of miR-15 Protects Against Cardiac Ischemic Injury
2011
Micro RNA mimicry blocks pulmonary fibrosis
2014
miR-221 Silencing Blocks Hepatocellular Carcinoma and Promotes Survival
2011
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex
2011
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
Therapeutic siRNA: state of the art
2020
Hallmarks of Cancer: The Next Generation
2011 Standout
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
2018 StandoutNobel
Cancer statistics, 2019
2019 Standout
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation
2012
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines
2013 StandoutNobel
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles
2012
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease
2012
Nucleotide signalling during inflammation
2014 StandoutNature
Hepatitis C virus—host interactions, replication, and viral assembly
2012
Treatment triumphs
2014 StandoutNatureNobel
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Hepatitis C viral protein translation: mechanisms and implications in developing antivirals
2011
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Barriers of hepatitis C virus interspecies transmission
2012
MicroRNA-122 Modulates the Rhythmic Expression Profile of the Circadian Deadenylase Nocturnin in Mouse Liver
2010
The changing landscape of atherosclerosis
2021 StandoutNature
New direct-acting antiviral agents for the treatment of hepatitis C virus infection and perspectives
2012
New advances in the molecular biology of hepatitis C virus infection: towards the identification of new treatment targets
2012
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Therapeutic targeting of microRNAs: current status and future challenges
2014
Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system
2014
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components
2011
A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration
2016 StandoutNobel
Hepatitis C Virus Subverts Liver-Specific miR-122 to Protect the Viral Genome from Exoribonuclease Xrn2
2014
Control of metastatic progression by microRNA regulatory networks
2013
Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors
2014
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
Hepatitis C virus and human miR-122: insights from the bench to the clinic
2014
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA
2010
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
MicroRNAs in neuronal function and dysfunction
2012
Animal Models for Hepatitis C
2013
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence
2017 StandoutNobel
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
miR‐210: More than a silent player in hypoxia
2011
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
2012
Decoy activity through microRNAs: the therapeutic implications
2012
Silencing of microRNA families by seed-targeting tiny LNAs
2011
miR-122 Stimulates Hepatitis C Virus RNA Synthesis by Altering the Balance of Viral RNAs Engaged in Replication versus Translation
2015
Metastatic colonization by circulating tumour cells
2016 StandoutNature
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice
2011
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
2013
HCV and the hepatic lipid pathway as a potential treatment target
2011
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
2012
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Development of micro RNA therapeutics is coming of age
2014
Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion
2015
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
In Vitro Antiviral Activity and Preclinical and Clinical Resistance Profile of Miravirsen, a Novel Anti-Hepatitis C Virus Therapeutic Targeting the Human Factor miR-122
2014
Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122
2010
Expression of MicroRNA miR-122 Facilitates an Efficient Replication in Nonhepatic Cells upon Infection with Hepatitis C Virus
2012
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
miRNA Deregulation in Cancer Cells and the Tumor Microenvironment
2016
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
MicroRNA-122 antagonism against hepatitis C virus genotypes 1–6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR
2011
Modulation of GB Virus B RNA Abundance by MicroRNA-122: Dependence on and Escape from MicroRNA-122 Restriction
2013
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure
2011
MicroRNA Regulation of Atherosclerosis
2016
New Hepatitis C Virus (HCV) Drugs and the Hope for a Cure: Concepts in Anti-HCV Drug Development
2014
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
2019 StandoutNobel
Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122
2010
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Human Ago2 Is Required for Efficient MicroRNA 122 Regulation of Hepatitis C Virus RNA Accumulation and Translation
2010
HepG2 Cells Expressing MicroRNA miR-122 Support the Entire Hepatitis C Virus Life Cycle
2011
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Novel Therapies for Hepatitis C: Insights from the Structure of the Virus
2011
Stabilization of hepatitis C virus RNA by an Ago2–miR-122 complex
2012
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Establishment of a Novel Permissive Cell Line for the Propagation of Hepatitis C Virus by Expression of MicroRNA miR122
2011
Works of Robert Persson being referenced
Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
2009 Science
Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo
2018
Coexpression of the membrane glycoproteins G1 and G2 of Hantaan virus is required for targeting to the Golgi complex
1992
Treatment of HCV Infection by Targeting MicroRNA
2013 Standout
A Locked Nucleic Acid Oligonucleotide Targeting MicroRNA 122 Is Well-Tolerated in Cynomolgus Monkeys
2012