Citation Impact
Citing Papers
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
2008 Standout
Circulating microRNAs as stable blood-based markers for cancer detection
2008 Standout
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15
2017 Science
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Untangling the ErbB signalling network
2001 Standout
Identification and Characterization of Novel Substrates of Trk Receptors in Developing Neurons
1998
MYC on the Path to Cancer
2012 Standout
Radiofrequency Ablation of Liver Cancer
2007
Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
2012 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
2004
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Cushing's syndrome
2015 Standout
Focal adhesion kinase: in command and control of cell motility
2005 Standout
Head and neck cancer
2008 Standout
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
2006 Standout
Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes
2007
Signaling Pathways Leading to Transcription and Translation Cooperatively Regulate the Transient Increase in Expression of c-Fos Protein
2001 StandoutNobel
Molecular determinants of resistance to antiandrogen therapy
2003 Standout
Translocation of Liposomes into Cancer Cells by Cell-Penetrating Peptides Penetratin and Tat: A Kinetic and Efficacy Study
2002
Palifermin for Oral Mucositis after Intensive Therapy for Hematologic Cancers
2004
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
2006
Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors
2011 Standout
The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3
2009 StandoutNobel
Phase II Trial Of Pegylated-liposomal Doxorubicin (Doxil™) In Sarcoma*
2003
EGF–ERBB signalling: towards the systems level
2006 Standout
Chromosomal aberrations in prostate cancer xenografts detected by comparative genomic hybridization
2002
Recent advances with liposomes as pharmaceutical carriers
2005 Standout
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Response to radiofrequency ablation of pulmonary tumours: a prospective, intention-to-treat, multicentre clinical trial (the RAPTURE study)
2008
Chemotherapy and the war on cancer
2005 Standout
Searching for the hereditary causes of renal-cell carcinoma
2004
Histone deacetylases and cancer: causes and therapies
2001 Standout
The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors
1997
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
A new human prostate carcinoma cell line, 22Rv1
1999
Curcumin and cancer: An “old-age” disease with an “age-old” solution
2008
Survival and Clinical Outcome of Patients with Neuroendocrine Tumors of the Gastroenteropancreatic Tract in a German Referral Center
2004
Recent Advances in Neuroblastoma
2010
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Hematopoietic Stem-Cell Transplantation
2006 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
2010 Standout
Neuroblastoma
2007 Standout
The Role of [18F]Fluorodeoxyglucose Positron Emission Tomography and [111In]-Diethylenetriaminepentaacetate-d -Phe-Pentetreotide Scintigraphy in the Localization of Ectopic Adrenocorticotropin-Secreting Tumors Causing Cushing’s Syndrome
2004
Activated Hepatic Stellate Cells Express Keratinocyte Growth Factor in Chronic Liver Disease
2004
Cushing's syndrome
2006 Standout
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice
1997
Selective degradation of splicing factor CAPERα by anticancer sulfonamides
2017
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
High chromosomal instability in brain metastases of colorectal carcinoma
2010
Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer
2004
No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue Syndrome
2011 StandoutNobel
Targeting the checkpoint kinases: chemosensitization versus chemoprotection
2004
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Hepatocellular carcinoma
2022 Standout
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
Characterization of an activated mutant of focal adhesion kinase: ‘SuperFAK’
2002
Tumour stem cells and drug resistance
2005 Standout
Emerging DNA topoisomerase inhibitors as anticancer drugs
2004
Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline
2016
A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
2002
Developmentally Regulated Use of Alternative Promoters Creates a Novel Platelet-Derived Growth Factor Receptor Transcript in Mouse Teratocarcinoma and Embryonic Stem Cells
1989
Velvet, a Dominant Egfr Mutation That Causes Wavy Hair and Defective Eyelid Development in Mice
2004 StandoutNobel
Tracking Micrometastasis to Multiple Organs with lacZ-tagged CWR22R Prostate Carcinoma Cells
2000
Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.
1988 StandoutNobel
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo.
2000
Ligand-independent dimerization of oncogenic v-erbB products involves covalent interactions
1996
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
Developmentally regulated use of alternative promoters creates a novel platelet-derived growth factor receptor transcript in mouse teratocarcinoma and embryonic stem cells.
1989
Epidermal growth factor receptor cytoplasmic domain mutations trigger ligand-independent transformation.
1990
Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update
2017 Standout
Phase II Trial of the Anti-GD2Monoclonal Antibody 3F8 and Granulocyte-Macrophage Colony-Stimulating Factor for Neuroblastoma
2001
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Stable expression of truncated inositol 1,4,5-trisphosphate receptor subunits in 3T3 fibroblasts. Coordinate signaling changes and differential suppression of cell growth and transformation.
1994 StandoutNobel
Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product.
1994
An analysis of vertebrate mRNA sequences: intimations of translational control.
1991 Standout
The Expanding Role of Systemic Therapy in Head and Neck Cancer
2004
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth.
1987
CWR22: androgen-dependent xenograft model derived from a primary human prostatic carcinoma.
1994
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Liquid Biopsies: Genotyping Circulating Tumor DNA
2014 Standout
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells
2013 StandoutNobel
Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma.
2002
Design and End Points of Clinical Trials for Patients With Progressive Prostate Cancer and Castrate Levels of Testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
2008 Standout
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Recombinant Origin of the Retrovirus XMRV
2011 Science
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
2003
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.
1994
Works of Robert Pelley being referenced
Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain.
1994
Phase II Trial of Liposomal Doxorubicin (Doxil®) in Advanced Soft Tissue Sarcomas
2000
A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC)
2006
Recent advances in systemic therapy for gastrointestinal neuroendocrine tumors
1999
Multidisciplinary management of colorectal brain metastases
2008
Xenografts of Primary Human Prostatic Carcinoma
1993
A phase II pharmacodynamic study of pyrazoloacridine in patients with metastatic colorectal cancer
2000
Predicting early mortality in resectable pancreatic adenocarcinoma: A cohort study
2015
Randomized Phase I Trial of Recombinant Human Keratinocyte Growth Factor Plus Chemotherapy: Potential Role as Mucosal Protectant
2003
Eradication of neuroblastoma cells in vitro by monoclonal antibody and human complement: method for purging autologous bone marrow.
1985
Dissecting the activating mutations in v-erbB of avian erythroblastosis virus strain R
1991
Neoadjuvant therapy for hepatocellular carcinoma: is there an optimal approach?
2007
A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinase
1995
Predictors of Survival After Radiofrequency Thermal Ablation of Colorectal Cancer Metastases to the Liver: A Prospective Study
2005
Modulation of erbB Kinase Activity and Oncogenic Potential by Single Point Mutations in the Glycine Loop of the Catalytic Domain
1994
Randomized trial of carboplatin plus amifostine versus carboplatin alone in patients with advanced solid tumors
1997
Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB
1988
Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential.
1990