Standout Papers
Citation Impact
Citing Papers
The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.
1994 Standout
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
2005 StandoutNobel
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease
2002 StandoutScienceNobel
Cycling vrille Expression Is Required for a Functional Drosophila Clock
1999 StandoutNobel
Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila
1997
Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function
2010 StandoutNobel
Direct and continuous assessment by cells of their position in a morphogen gradient
1995 StandoutNatureNobel
Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila.
1995
Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation
1999
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning
2002 Nature
An Autoregulatory Cascade of EGF Receptor Signaling Patterns the Drosophila Egg
1998
Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor
1994
Interpretation of a BMP Activity Gradient in Drosophila Embryos Depends on Synergistic Signaling by Two Type I Receptors, SAX and TKV
1998
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila
1999 Nature
Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4
1996 Standout
A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation
1994 StandoutNobel
Race: a drosophila homologue of the angiotensin converting enzyme
1995
Spatially Restricted Activation of the SAX Receptor by SCW Modulates DPP/TKV Signaling in Drosophila Dorsal–Ventral Patterning
1998
Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo
2003 Nobel
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
Morphogen gradients: new insights from DPP
1999
Sequence, biochemical characterization, and developmental expression of a new member of the TGF-β superfamily in Drosophila melanogaster
1992
decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo
1992
miR-9a Minimizes the Phenotypic Impact of Genomic Diversity by Buffering a Transcription Factor
2013
Induction of epidermis and inhibition of neural fate by Bmp-4
1995 Nature
Zebrafish Radar: A new member of the TGF-β superfamily defines dorsal regions of the neural plate and the embryonic retina
1995
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
1994
Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.
1995
The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor
1996
Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis
2002
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo
1995
The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1
1991
Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF
1997
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Production of a DPP Activity Gradient in the Early Drosophila Embryo through the Opposing Actions of the SOG and TLD Proteins
1997
Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila
1994
Bone morphogenetic proteins: multifunctional regulators of vertebrate development.
1996 Standout
The immune response of Drosophila
2003 StandoutNatureNobel
Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis
1993 StandoutNobel
The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFβ superfamily
1992
A common plan for dorsoventral patterning in Bilateria
1996 Nature
Mammalian MAP kinase signalling cascades
2001 StandoutNature
schnurri is required for drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1
1995
Signal transduction by a protease cascade
1999
Axes, boundaries and coordinates: The ABCs of fly leg development
1995
The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo
1994
Patterning the Xenopus blastula
1997
Problems and paradigms: Morphogens and pattern formation
1997
Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic
1994
fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
1994 StandoutNobel
Asymmetric Sorting of Ash1p in Yeast Results from Inhibition of Translation by Localization Elements in the mRNA
2002
A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin
1995 Nature
pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo
1993
Conservation of dorsal-ventral patterning in arthropods and chordates
1996
Control of cell pattern in the neural tube: Regulation of cell differentiation by dorsalin-1, a novel TGFβ family member
1993
cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates
1992 StandoutNobel
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
The vrille Gene of Drosophila Is a Maternal Enhancer of decapentaplegic and Encodes a New Member of the bZIP Family of Transcription Factors
1997
Drosophila immunity
1997
The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development
2002 StandoutNobel
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Dpp signaling thresholds in the dorsal ectoderm of the Drosophila embryo
2000
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
2000 StandoutNobel
Mechanical control of tissue and organ development
2010
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
The decapentaplegic Core Promoter Region Plays an Integral Role in the Spatial Control of Transcription
1995
Mutational analysis of the Drosophila tolloid gene, a human BMP-1 homolog
1994
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.
1994
The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response
2000 StandoutNobel
dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo.
1992
A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation
1999 StandoutNobel
Nuclear reprogramming and stem cell creation
2003 StandoutNobel
Cross regulation of decapentaplegic and Ultrabithorax transcription in the embryonic visceral mesoderm of Drosophila
1993
An experimental system for analyzing response to a morphogen gradient.
1996 StandoutNobel
Localized enhancement and repression of the activity of the TGF-P family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo
1992
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Neural Science
2000 StandoutNobel
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
1998 StandoutNobel
Endoderm induction by the organizer-secreted factors chordin and noggin in Xenopus animal caps.
1996
DNA Repair in Drosophila
2000
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1
1997
Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning
1995
Angiotensin-converting enzyme and male fertility
1998 StandoutNobel
Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing
1997
The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression.
1993
p24 Proteins and Quality Control of LIN-12 and GLP-1 Trafficking in Caenorhabditis elegans
1999
Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.
1995
Conservation of neurogenic genes and mechanisms
1999
Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal.
1993
Disulfide cross-linking in crude embryonic lysates reveals three complexes of the Drosophila morphogen dorsal and its inhibitor cactus.
1994 StandoutNobel
Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region
2001
Human DNA Repair Genes
2001 StandoutScienceNobel
Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes
1992 StandoutNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.
1993
Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes
1998 StandoutNobel
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
1994 StandoutNatureNobel
Biogenesis and germline functions of piRNAs
2007
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
From intestine to muscle: Nuclear reprogramming through defective cloned embryos
2002 StandoutNobel
Morphogen gradient interpretation
2001 StandoutNatureNobel
The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants.
1992 StandoutNobel
A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus.
1995 StandoutNobel
Works of Robert P. Ray being referenced
okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis
1998
Localization of gurken RNA in Drosophila Oogenesis Requires Elements in the 5′ and 3′ Regions of the Transcript
2000
Intercellular signaling and the polarization of body axes during Drosophila oogenesis.
1996
u-shaped encodes a zinc finger protein that regulates the proneural genesachaete and scute during the formation of bristles in Drosophila
1997
crossveinless-cis a RhoGAP required for actin reorganisation during morphogenesis
2005
An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo
1993
The control of cell fate along the dorsal-ventral axis of the Drosophila embryo
1991 StandoutNobel