Citation Impact
Citing Papers
Alzheimer's disease β-amyloid peptides are released in association with exosomes
2006
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide.
1996
Hallmarks of Cancer: The Next Generation
2011 Standout
Complex Genetic Disease: Can Genetic Strategies in Alzheimer's Disease and New Genetic Mechanisms Be Applied to Epilepsy?
1994
Advances in the Cellular and Molecular Biology of the Beta-Amyloid Protein in Alzheimer 's Disease
2002
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Amyloid β Protein (Aβ) in Alzheimeri's Disease Brain
1995
Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in down Syndrome
1995
Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths
1994
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
2009 Standout
Cerebrovascular transport of Alzheimer's amyloidβ and apolipoproteins J and E: Possible anti-amyloidogenic role of the blood-brain barrier
1996
X11 Interaction with β-Amyloid Precursor Protein Modulates Its Cellular Stabilization and Reduces Amyloid β-Protein Secretion
1998
Soluble multimeric Alzheimer β(1–40) pre-amyloid complexes in dilute solution
1995
Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)
1994 Standout
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
2000 StandoutNature
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Plasma Levels of amyloid β proteins Aβ1–40 and Aβ1–42(43) are elevated in Down's syndrome
1997
Rapid induction of Alzheimer A beta amyloid formation by zinc
1994 Science
Amyloids and Are Generated Intracellularly in Cultured Human Neurons and Their Secretion Increases with Maturation
1996
Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide
1993 Nature
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
2002
Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid β protein precursor
1993
Ectodomain Phosphorylation of β-Amyloid Precursor Protein at Two Distinct Cellular Locations
1997
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
1990 StandoutNobel
Genetics and molecular advances in Alzheimer's disease
1993
Aggregation of Secreted Amyloid β-Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture
1995
Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide
1995
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
1998
Protein folding and misfolding
2003 StandoutNature
Structural and kinetic features of amyloid β-protein fibrillogenesis
1998
Chemotaxis in Eukaryotic Cells: A Focus on Leukocytes and Dictyostelium
1988
Immunity, Inflammation, and Cancer
2010 Standout
Interactions of Alzheimer amyloid‐β peptides with glycosaminoglycans
1999
Cancer micrometastases
2009
Insertion of Alzheimer’s Aβ40 Peptide into Lipid Monolayers
2004
Gene Structure and Transcriptional Regulation of Human Gal β1,4(3) GlcNAc α2,3-Sialyltransferase VI (hST3Gal VI) Gene in Prostate Cancer Cell Line
2001
Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic
1995
Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry
1998
APP Processing and Synaptic Function
2003
The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
1993 Standout
Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF
1993
Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated
2010
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
1994 Nature
Does tumour dormancy offer a therapeutic target?
2010
Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice
2005 Standout
Enhanced Production and Oligomerization of the 42-residue Amyloid β-Protein by Chinese Hamster Ovary Cells Stably Expressing Mutant Presenilins
1997
Amyloid β-Protein Fibrillogenesis
1997
Receptor-Mediated Transport of Human Amyloid β-Protein 1–40 and 1–42 at the Blood–Brain Barrier
1999
Morphology and Toxicity of Aβ-(1-42) Dimer Derived from Neuritic and Vascular Amyloid Deposits of Alzheimer's Disease
1996
Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier
2000
Rapid Communication: Characterization of β‐Amyloid Peptide from Human Cerebrospinal Fluid
1993
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Chaperoning Alzheimer's amyloids
1994
Molecular Genetics of Alzheimer's Disease
1993
Molecular cloning of the cDNA for a human amyloid precursor protein homolog: Evidence for a multigene family
1993
Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the β-amyloid precursor protein
1999
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways
1998
Mutagenesis Identifies New Signals for β-Amyloid Precursor Protein Endocytosis, Turnover, and the Generation of Secreted Fragments, Including Aβ42
1999
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
1993
Field-resolved infrared spectroscopy of biological systems
2020 StandoutNatureNobel
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
Amyloid β-peptide is produced by cultured cells during normal metabolism
1992 StandoutNature
Amyloid, the presenilins and Alzheimer's disease
1997
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Novel approaches to target the microenvironment of bone metastasis
2021
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
Polyclonals to β-amyloid(1–42) identify most plaque and vascular deposits in Alzheimer cortex, but not striatum
1994
Detection of single amyloid β-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy
1998
Translating cell biology into therapeutic advances in Alzheimer's disease
1999 Nature
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Revisiting biomarker discovery by plasma proteomics
2017
High tissue content of soluble beta 1-40 is linked to cerebral amyloid angiopathy.
1994
Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor
1993 Science
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
1992 StandoutNature
Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments
1997 StandoutNobel
Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices.
1993
Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).
1994
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
1996 StandoutScience
Polarized secretion of beta-amyloid precursor proteinand amyloid beta-peptide in MDCK cells.
1994
MUTANT GENES IN FAMILIAL ALZHEIMER'S DISEASE AND TRANSGENIC MODELS
1998
A Century of Alzheimer's Disease
2006 StandoutScience
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Accelerated A Deposition in APPswe/PS1 E9 Mice with Hemizygous Deletions of TTR (Transthyretin)
2007
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins
1998 Standout
Secreted Forms of the Amyloid-β Precursor Protein Are Ligands for the Class A Scavenger Receptor
2001
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative.
1994
Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
1997 StandoutScience
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.
1993
Amyloid precursor protein processing and Aβ 42 deposition in a transgenic mouse model of Alzheimer disease
1997
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein
1999
Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise.
1994
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals
2002 StandoutNobel
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
The cerebrospinal-fluid soluble form of Alzheimer's amyloid β is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex
1993
Calcium and Neuronal Injury in Alzheimer's Disease
1994
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Transthyretin sequesters amyloid beta protein and prevents amyloid formation.
1994
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Genetic Dissection of Complex Traits
1994 StandoutScience
Selective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor protein.
1994
Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics
2003
Generation of Alzheimer β-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
1997
Reduction of β‐amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease
1995
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.
1993
Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers.
1996
beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.
1993
Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.
1995
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Alzheimer Amyloid Protein Precursor in the Rat Hippocampus: Transport and Processing through the Perforant Path
1998
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease.
1993
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor
1994
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.
1996
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Apolipoprotein J and Alzheimer's amyloid β solubility
1996
Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
2003 StandoutScience
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
1993 Standout
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission
2003 StandoutNobel
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.
1994
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
2001
Works of Robert McCormack being referenced
Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer
2016
Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment
2008
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
1992 Nature
Molecular forms of prostate-specific antigen and the human kallikrein gene family: A new era
1995
Chemotactic deactivation of human neutrophils: evidence for nonspecific and specific components
1978
Circulating Tumor Cell Number as a Response Measure of Prolonged Survival for Metastatic Castration-Resistant Prostate Cancer: A Comparison With Prostate-Specific Antigen Across Five Randomized Phase III Clinical Trials
2017
Circulating Tumor Cells in Peripheral Blood Samples From Patients With Increased Serum Prostate Specific Antigen: Initial Results in Early Prostate Cancer
2008
Breaking a Vicious Cycle
2013