Citation Impact
Citing Papers
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Genetic determinants of hepatic steatosis in man
2011
Synthesis of carbocyclic nucleosides
1994
Molecular mediators of hepatic steatosis and liver injury
2004 Standout
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Fluorinated nucleosides: Synthesis and biological implication
2008
Imaging beyond the proteome
2012 StandoutNobel
Clinical Trial of the Pan-Caspase Inhibitor, IDN-6556, in Human Liver Preservation Injury
2006
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Liver fibrosis
2005 Standout
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
2007
In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease
2006
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal
2009
Synthesis and Properties of Allenic Natural Products and Pharmaceuticals
2004 Standout
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
2007
Antiviral Agents: Characteristic Activity Spectrum Depending on the Molecular Target With Which They Interact
1993
Evolution of Inflammation in Nonalcoholic Fatty Liver Disease: The Multiple Parallel Hits Hypothesis
2010 Standout
5‐Iodo‐3‐Ethoxypyrazoles: An Entry Point to New Chemical Entities
2010
Apoptosis: The nexus of liver injury and fibrosis
2004
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
2008 Standout
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
Cytokeratin-18 Fragment Levels as Noninvasive Biomarkers for Nonalcoholic Steatohepatitis
2009
Lysosomes in cell death
2004
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Uric acid and anti-TNF antibody improve mitochondrial dysfunction in ob/ob mice
2006
3 The Medicinal Chemistry of the Azido Group
1994
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
2020 Standout
Identification of a potent and selective non-basic cathepsin K inhibitor
2006
Treating hepatitis C
2005 StandoutNobel
Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications
2011
Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine
2009
Proteasome inhibition induces hepatic stellate cell apoptosis
2006
Caspase-independent cell death
2005
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
EMT: 2016
2016 Standout
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
2010 Standout
Chemistry in living systems
2005 StandoutNobel
Fructose as a key player in the development of fatty liver disease
2013
Animal models of nonalcoholic fatty liver disease
2010
Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease
2016
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes
2007 StandoutNobel
Cellular and Molecular Mechanisms of Liver Injury
2008
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Lessons from animal models of NASH
2005
A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase
2018 StandoutNobel
Nonalcoholic fatty liver disease
2005 Standout
Increased Hepatic and Circulating Interleukin-6 Levels in Human Nonalcoholic Steatohepatitis
2008
NASH: a mitochondrial disease
2005
Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease
2007
From Fat to Inflammation
2006
Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease
2008
Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes
2007
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis
2010
Protease inhibitors targeting coronavirus and filovirus entry
2015
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Fluorine in medicinal chemistry
2007 Standout
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Synthese und Eigenschaften allenischer Natur‐ und Wirkstoffe
2004
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Cell Death Independent of Caspases: A Review
2005
The pan‐caspase inhibitor Emricasan (IDN ‐6556) decreases liver injury and fibrosis in a murine model of non‐alcoholic steatohepatitis
2014
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
SOCS1 Is a Suppressor of Liver Fibrosis and Hepatitis-induced Carcinogenesis
2004
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
A Field Guide to Foldamers
2001 Standout
Azidonucleosides: Synthesis, Reactions, and Biological Properties
2002
Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression
2011
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Chiral Allenes via Alkynylogous Mukaiyama Aldol Reaction
2016 StandoutNobel
Transition Metal Catalyzed Cycloisomerizations of 1,n-Allenynes and -Allenenes
2011 Standout
Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions
2011 Standout
Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012
2012
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
The Allylic Azide Rearrangement: Achieving Selectivity
2005 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Nonalcoholic Fatty Liver Disease
2015 Standout
Some Typical Advances in the Synthetic Applications of Allenes
2005 Standout
Works of Robert M. Rydzewski being referenced
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-α expression via a lysosomal pathway
2004
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides
1992
Peptidic 1-cyanopyrrolidines: synthesis and SAR of a series of potent, selective cathepsin inhibitors
2002
Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase
1988
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis
2003
A stereocontrolled synthesis of a novel prostacyclin analog “allene-carbacyclin”. Application of molecular mechanics calculations to organic synthesis.
1987
Optimization of Subsite Binding to the β5 Subunit of the Human 20S Proteasome Using Vinyl Sulfones and 2-Keto-1,3,4-oxadiazoles: Syntheses and Cellular Properties of Potent, Selective Proteasome Inhibitors
2006
4-Substituted-5(3)-carbamoyl-3(5)-(2-deoxy-β-D -ribofuranosyl)pyrazoles. Application of Palladium Catalyzed Glycal Coupling Methodology to the Synthesis of Pyrazofurin Analogs
1997
An allylic azide route to 4'-azido carbocyclic nucleosides. Synthesis of (.+-.)-(1'.alpha.,2'.alpha.,3'.beta.)- and (.+-.)-(1'.alpha.,2'.beta.,3'.beta.)-1-[1-azido-2-hydroxy-1-(hydroxymethyl)-3-cyclopentyl]thymine
1992
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis
2003
Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L
2000