Citation Impact
Citing Papers
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
2004 StandoutScience
Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens
2003 StandoutScienceNobel
Electrically monitoring DNA repair by photolyase
2005 StandoutNobel
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
Sirtuins as regulators of metabolism and healthspan
2012 Standout
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBH
2010
Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
2007
Inflammation and metabolic disorders
2006 StandoutNature
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
2005 Nature
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
An assay for DNA photolyases using non-radioactive DNA and restriction enzymes
1993
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
The Molecular Physiology of Hepatic Nuclear Factor 3 in the Regulation of Gluconeogenesis
2000
Retinoid regulation of the phosphoenolpyruvate carboxykinase gene in liver
2002
Dietary Polyphenols and the Prevention of Diseases
2005 Standout
Autophagy regulates lipid metabolism
2009 StandoutNature
The metabolic syndrome
2010 Standout
The Phosphoenolpyruvate Carboxykinase Gene Glucocorticoid Response Unit: Identification of the Functional Domains of Accessory Factors HNF3β (Hepatic Nuclear Factor-3β) and HNF4 and the Necessity of Proper Alignment of Their Cognate Binding Sites
1999
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
Hepatocyte CYP2E1 Overexpression and Steatohepatitis Lead to Impaired Hepatic Insulin Signaling
2005
Peroxisome Proliferator-activated Receptor-γ Coactivator-1α Controls Transcription of the Sirt3 Gene, an Essential Component of the Thermogenic Brown Adipocyte Phenotype
2011
Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16
2003
SRC-1 and GRIP1 Coactivate Transcription with Hepatocyte Nuclear Factor 4
1998
A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
2002
PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL
1998 Standout
The metabolic syndrome
2005 Standout
Coffee, Decaffeinated Coffee, and Tea Consumption in Relation to Incident Type 2 Diabetes Mellitus
2009
Restriction enzymes and their isoschizomers
1990 StandoutNobel
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Human aquaporin adipose (AQPap) gene
2002
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
2006
Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway
2003
The Major Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate, Inhibits Obesity, Metabolic Syndrome, and Fatty Liver Disease in High-Fat–Fed Mice
2008
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
Genomic Structure and Insulin-mediated Repression of the Aquaporin Adipose (AQPap), Adipose-specific Glycerol Channel
2001
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
2002 StandoutNature
What We Talk About When We Talk About Fat
2014 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
2003 Nature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*
1994
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Steroid hormone receptors: Many Actors in search of a plot
1995 Standout
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
The Hallmarks of Aging
2013 Standout
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
2005 StandoutNature
The RXR heterodimers and orphan receptors
1995 Standout
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Hepatocellular Carcinoma
2011 Standout
Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.
1996
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
1994 Standout
Mammalian SIRT1 Represses Forkhead Transcription Factors
2004
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
IRS proteins and the common path to diabetes
2002
REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE EXPRESSION
1997
Xenopus laevis B4, an intron-containing oocyte-specific linker histone-encoding gene
1994
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
PGC-1α regulates a HIF2α-dependent switch in skeletal muscle fiber types
2010
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Orphan Nuclear Receptors: From Gene to Function*
1999
Hepatic Nuclear Factor 3- and Hormone-Regulated Expression of the Phosphoenolpyruvate Carboxykinase and Insulin-Like Growth Factor-Binding Protein 1 Genes
1995
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c
2002
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Coordinated Regulation of Fat-Specific and Liver-Specific Glycerol Channels, Aquaporin Adipose and Aquaporin 9
2002
Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors
2008
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
The Genetics of Aging
2001 StandoutNobel
PGC-1α controls hepatitis B virus through nutritional signals
2006
PPARγ2 Regulates Adipose Expression of the Phosphoenolpyruvate Carboxykinase Gene
1995
Noncoding RNA Gas5 Is a Growth Arrest– and Starvation-Associated Repressor of the Glucocorticoid Receptor
2010
Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
2003
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Restriction and modification enzymes and their recognition sequences
1981 StandoutNobel
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation
2010 StandoutNobel
Isotation and characterisation of Dral, a type II restriction endonuclease recognisting a aequence containing only A:T basepairs, and inhibition of its activity by uv irradiation of substrate DNA
1983
Aquaglyceroporin AQP9: Solute permeation and metabolic control of expression in liver
2003 StandoutNobel
Effects of Green Tea Polyphenol (−)-Epigallocatechin-3-gallate on Newly Developed High-Fat/Western-Style Diet-Induced Obesity and Metabolic Syndrome in Mice
2011
Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): Requirement for hepatocyte nuclear factor 4α in gluconeogenesis
2003
Current Understanding of the Molecular Actions of Vitamin D
1998
Exclusive Homodimerization of the Orphan Receptor Hepatocyte Nuclear Factor 4 Defines a New Subclass of Nuclear Receptors
1995
Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
2003 Nobel
Deletion, But Not Antagonism, of the Mouse Growth Hormone Receptor Results in Severely Decreased Body Weights, Insulin, and Insulin-Like Growth Factor I Levels and Increased Life Span
2003
The Many Forks in FOXO's Road
2003
Works of Robert K. Hall being referenced
BLOCKAGE OF RESTRICTION ENDONUCLEASE CLEAVAGE BY THYMINE DIMERS
1982
The Synergistic Effect of Dexamethasone and All-trans-retinoic Acid on Hepatic Phosphoenolpyruvate Carboxykinase Gene Expression Involves the Coactivator p300
2004
Insulin Regulates Expression of Metabolic Genes through Divergent Signaling Pathways
1999
Estrogen-related Receptor α Is a Repressor of Phosphoenolpyruvate Carboxykinase Gene Transcription
2005
Regulation of Phosphoenolpyruvate Carboxykinase and Insulin-like Growth Factor-binding Protein-1 Gene Expression by Insulin
2000
Regulation of the Xenopus laevis transcription factor IIIA gene during oogenesis and early embryogenesis: Negative elements repress the O-TFIIIA promoter in embryonic cells
1991
Peroxisome Proliferator-Activated Receptor γ Coactivator-1α, as a Transcription Amplifier, Is Not Essential for Basal and Hormone-Induced Phosphoenolpyruvate Carboxykinase Gene Expression
2004
Epigallocatechin Gallate, a Constituent of Green Tea, Represses Hepatic Glucose Production
2002
Transcription Factor IIIA Gene Expression in Xenopus Oocytes Utilizes a Transcription Factor Similar to the Major Late Transcription Factor
1989
Retinoid receptors cause distortion of the retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter
1995
The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.
1995
Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter.
1994
Transcription factor IIIA gene expression in Xenopus oocytes utilizes a transcription factor similar to the major late transcription factor.
1989
Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex.
1992