Citation Impact
Citing Papers
Extracellular vesicles and viruses: Are they close relatives?
2016
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
1991
Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin
1989
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
Drug Combinations and Effect Parameters of Zidovudine, Stavudine, and Nevirapine in Standardized Drug-Sensitive and Resistant HIV Type 1 Strains*
1996
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
1996 Standout
Differential Alteration of the Anti-HIV-1 Effect of Phosphorothioate Oligonucleotide S-dC28 by AZT, Interferon-Alpha, and Dextran Sulfate
1991
Gene Therapy of the Immune System
1993
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
A novel, dipyridodiazepinone inhibitor of HIV-1 reverse transcriptase acts through a nonsubstrate binding site
1991
Hematopoietic stem cell compartment: Acute and late effects of radiation therapy and chemotherapy
1995
Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors
1995
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design
1995
Chicken “erythroid” cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent
1992
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
A Short-Term Clinical Evaluation of L-697,661, a Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase
1993
HIV as the cause of AIDS
1996 StandoutNobel
Phenylethylthiazolylthiourea (PETT) Non-nucleoside Inhibitors of HIV-1 and HIV-2 Reverse Transcriptases
2000
Sak Serine-Threonine Kinase Acts as an Effector of Tec Tyrosine Kinase
2001
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors
1995
Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template
1991
HIV reverse transcriptase structure-function relationships
1991
Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions
1997
HIV Drug Resistance
1992
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones
1991
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Identification of a constitutively active mutant of JAK3 by retroviral expression screening
2006
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor
1998
High resolution structures of HIV-1 RT from four RT–inhibitor complexes
1995
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor α-APA R 95845 at 2.8 å resolution
1995
Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity.
1991
Tyrosine kinase(s) regulate apoptosis and bcl-2 expression in a growth factor-dependent cell line.
1993
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
1992
Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia
1984 Nature
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
1994
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases
1979 StandoutNobel
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates.
1978 StandoutNobel
Chimeric human immunodeficiency virus type 1/type 2 reverse transcriptases display reversed sensitivity to nonnucleoside analog inhibitors.
1991
Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy
1994
Structural Proteins of Mammalian Oncogenic RNA Viruses: Multiple Antigenic Determinants of the Major Internal Protein and Envelope Glycoprotein
1974
HOST GENETIC CONTROL OF RECOVERY FROM FRIEND LEUKEMIA VIRUS-INDUCED SPLENOMEGALY
1974
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
THE GREEN FLUORESCENT PROTEIN
1998 StandoutNobel
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
Regulation of immune response to tumor antigen: interference with syngeneic tumor immunity by anti-IA alloantisera.
1979 StandoutNobel
Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity
1985
Initiation of Minus-Strand DNA Synthesis by Human Immunodeficiency Virus Type 1 Reverse Transcriptase
1999
Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution.
1991
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations
1992 Nature
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Structural Relationship of Bacterial RecA Proteins to Recombination Proteins from Bacteriophage T4 and Yeast
1993 StandoutScienceNobel
Correct integration of retroviral DNA in vitro
1987 StandoutNobel
Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.
1989
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase
1993
IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo
1985
DNA-mediated genetic transformation of mouse embryos and bone marrow—a review
1985
High-frequency germ-line transmission of plasmid DNA sequences injected into fertilized zebrafish eggs.
1991 StandoutNobel
Augmentation of natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic target cells
1977
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
1986 StandoutNatureNobel
A new reporter cell line to monitor HIV infection and drug susceptibilityin vitro
1997
Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors
1991
Susceptibility to Friend helper virus leukemias in CXB recombinant inbred mice.
1983
Mechanism of Inhibition of HIV-1 Reverse Transcriptase by Nonnucleoside Inhibitors
1995 Science
Implication of the tRNA Initiation Step for Human Immunodeficiency Virus Type 1 Reverse Transcriptase in the Mechanism of 3‘-Azido-3‘-deoxythymidine (AZT) Resistance
1998
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Histocompatibility-Linked Immune Response Genes
1972 StandoutScienceNobel
Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene
1983 Nature
Gene correction in hematopoietic progenitor cells by homologous recombination
2000 StandoutNobel
The physiopathology of friend leukemia
1979
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Replication of HIV-1 in Dendritic Cell-Derived Syncytia at the Mucosal Surface of the Adenoid
1996 StandoutScienceNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
LEUKEMIA-ASSOCIATED TRANSPLANTATION ANTIGENS RELATED TO MURINE LEUKEMIA VIRUS
1973
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture.
1991
Viral dynamics in human immunodeficiency virus type 1 infection
1995 StandoutNature
A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice
1987 StandoutNatureNobel
Engraftment of a clonal bone marrow stromal cell line in vivo stimulates hematopoietic recovery from total body irradiation.
1987
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors.
1993
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors.
1992
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site
1999 StandoutNobel
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors
1992
Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro.
1988 StandoutNobel
Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.
1991
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.
1993
Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors
1996
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
The Gene for Erythropoietin Receptor Is Expressed in Multipotential Hematopoietic and Embryonal Stem Cells: Evidence for Differentiation Stage-Specific Regulation
1992
Comprehensive mutant enzyme and viral variant assessment of human immunodeficiency virus type 1 reverse transcriptase resistance to nonnucleoside inhibitors
1993
Radioimmunoassay for intact Gross mouse leukemia virus.
1976 StandoutNobel
A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS
1975 StandoutNobel
T Cells, T Cell Recognition Structures, and the Major Histocompatibility Complex
1978 StandoutNobel
The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation.
1992
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Endogenous type-C RNA viruses of mammalian cells
1976
Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice
1985
Efficient insertion of genes into the mouse germ line via retroviral vectors.
1985
Characterization of the binding site for nevirapine (BI-RG-587), a nonnucleoside inhibitor of human immunodeficiency virus type-1 reverse transcriptase
1991
The Fv-1 Gene of the Mouse and its Control of Murine Leukemia Virus Replication
1979
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor
1997
Works of Robert J. Eckner being referenced
Host-Induced Changes in Infectivity of Friend Spleen Focus-Forming Virus<xref ref-type="fn" rid="FN2">2</xref>
1970
Expression of a Retrovirus Encoding Human HPRT in Mice
1984 Science
BI-RG-587 is active against zidovudine-resistant human immunodeficiency virus type 1 and synergistic with zidovudine
1991
MECHANISM OF GENETIC RESISTANCE TO IMMUNE SUPPRESSION BY FRIEND LEUKEMIA VIRUS: THE ROLE OF MARROW‐DEPENDENT CELLS*
1976
Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.
1983
Release of spleen focus-forming virus (SFFV) from differentiation inducible promyelocytic leukemia cell lines transformed in vitro by friend leukemia virus
1980
In vitro quantitation of lethal and physiologic effects of total body irradiation on stromal and hematopoietic stem cells in continuous bone marrow cultures from Rf mice
1982
A CLASSIFICATION OF THE MURINE LEUKEMIA VIRUSES
1972
Helper-Dependent Properties of Friend Spleen Focus-Forming Virus: Effect of the Fv-1 Gene on the Late Stages in Virus Synthesis
1973
MECHANISMS OF GENETIC RESISTANCE TO FRIEND VIRUS LEUKEMIA IN MICE
1974
Pool Size of Pluripotential Hematopoietic Stem Cells Increased in Continuous Bone Marrow Culture by Friend Spleen Focus-Forming Virus<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>
1983
Defective Friend Spleen Focus-Forming Virus: Interfering Properties and Isolation Free from Standard Leukemia-Inducing Helper Virus
1977
Isolation and Characterization of a Lymphatic Leukemia Virus in the Friend Virus Complex<xref ref-type="fn" rid="FN2">2</xref>
1971
Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor
1990 Science