Citation Impact
Citing Papers
Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
2010
CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract
2004 Standout
Regulation of learning and memory by meningeal immunity: a key role for IL-4
2010
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
2013 Standout
Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720
2004
Custom Cerium Oxide Nanoparticles Protect against a Free Radical Mediated Autoimmune Degenerative Disease in the Brain
2013
Sphingosine-1-phosphate signaling in the cardiovascular system
2007
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
2010 Standout
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Finding a way out: lymphocyte egress from lymphoid organs
2007
Homing and cellular traffic in lymph nodes
2003
Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy
2004
Pathogenesis and therapy of psoriasis
2007 StandoutNature
The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR
2009
Sphingolipids and their metabolism in physiology and disease
2017 Standout
Chemoattractants and their receptors in homeostasis and inflammation
2004
The therapeutic potential of modulating the ceramide/sphingomyelin pathway
2002
G protein-independent cell-based assays for drug discovery on seven-transmembrane receptors
2008
The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
2007
Systematic identification of regulatory proteins critical for T-cell activation
2003
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
FTY720: Placebo‐Controlled Study of the Effect on Cardiac Rate and Rhythm in Healthy Subjects
2006
Cellular pathophysiology of ischemic acute kidney injury
2011 Standout
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
New immunosuppressants with potential implication in multiple sclerosis
2004
Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors
2010
Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice
2004
Principles of bioactive lipid signalling: lessons from sphingolipids
2008 Standout
Sphingosine 1-phosphate and lysophosphatidic acid receptors: agonist and antagonist binding and progress toward development of receptor-specific ligands
2004
The Role of Sphingosine 1‐Phosphate Receptors in the Trafficking of Hematopoietic Progenitor Cells
2005
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder
2007 Standout
FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity
2002
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Prolonged Exposure to Sphingosine 1–Phosphate Receptor-1 Agonists Exacerbates Vascular Leak, Fibrosis, and Mortality after Lung Injury
2010
Calcitonin gene-related peptide: Multiple actions, multiple receptors
1992
Dissecting fibrosis: therapeutic insights from the small-molecule toolbox
2015
Multiple sclerosis
2008 Standout
Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren
2007
The alliance of sphingosine-1-phosphate and its receptors in immunity
2008
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function
2004
Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases
2003
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney
2006
Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment
2003
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer
2012
Neuroanatomical Localization, Pharmacological Characterization and Functions of CGRP, Related Peptides and Their Receptors
1997
Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules
2009
FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system
2009
Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone
2004
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer
2013
Molecular regulation of angiogenesis and lymphangiogenesis
2007 Standout
Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism
2015
Chemokine regulation of naıve T cell traffic in health and disease
2003
Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study
2003
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Membrane lipids: where they are and how they behave
2008 Standout
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
2010
Egress: a receptor‐regulated step in lymphocyte trafficking
2003
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases
2006
Lysophospholipid receptors: Signalling, pharmacology and regulation by lysophospholipid metabolism
2006
FTY720: ALTERED LYMPHOCYTE TRAFFIC RESULTS IN ALLOGRAFT PROTECTION
2001
Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis
2006
Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology
2007
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Natural products to drugs: natural product derived compounds in clinical trials
2005
Structural and functional characteristics of S1P receptors
2004
Lymphoid organ development and cell migration
2003
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss
2014
The acute respiratory distress syndrome
2012 Standout
Immunosuppressive Drugs for Kidney Transplantation
2004 Standout
Sphingosine-1-phosphate: an enigmatic signalling lipid
2003 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate
2004
Physiological and pathological actions of sphingosine 1-phosphate
2004
Sphingosine 1-phosphate in coagulation and inflammation
2011
Brain Penetration of the Oral Immunomodulatory Drug FTY720 and Its Phosphorylation in the Central Nervous System during Experimental Autoimmune Encephalomyelitis: Consequences for Mode of Action in Multiple Sclerosis
2007
Expression of the Sphingosine 1-Phosphate Receptor, S1P1, on T-cells Controls Thymic Emigration
2004
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
2003
FTY720 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Drug Resistance
2005
Oral fingolimod (FTY720) in multiple sclerosis
2009
Strength of TCR–Peptide/MHC Interactions and In Vivo T Cell Responses
2011 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Calcitonin Gene-Related Peptide Decreases Expression of HLA-DR and CD86 by Human Dendritic Cells and Dampens Dendritic Cell-Driven T Cell-Proliferative Responses Via the Type I Calcitonin Gene-Related Peptide Receptor
2000 StandoutNobel
FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis
2008
A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels
2006 StandoutNobel
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
2018 Standout
Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling
2005
CHEMOKINES, SPHINGOSINE-1-PHOSPHATE, AND CELL MIGRATION IN SECONDARY LYMPHOID ORGANS
2004
Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists
2002 StandoutScience
Drugging Sphingosine Kinases
2014
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
2004 StandoutNobel
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Activation‐regulated expression and chemotactic function of sphingosine 1‐phosphate receptors in mouse splenic T cells
2002
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
The Sphingosine 1-Phosphate Receptor Agonist FTY720 Differentially Affects the Sequestration of CD4+/CD25+ T-Regulatory Cells and Enhances Their Functional Activity
2005
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
FTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosis
2007
The therapeutic potential of modulating the ceramide/sphingomyelin pathway
2002
Lysophospholipid Receptors: Signaling and Biology
2004
A novel modifier of regulatory T cells
2009 StandoutNobel
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Physiology of Microglia
2011 Standout
Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator
2013
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
2006
Cutting Edge: Suppression of T Cell Chemotaxis by Sphingosine 1-Phosphate
2002
Works of Robert Hof being referenced
FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression
2001
The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors
2002
Effects of hCGRP I and II on gastric blood flow and acid secretion in anesthetized rabbits
1989