Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
2012 StandoutNobel
Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
2013
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Hypoxia and loss of PHD 2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis
2015
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization
2015
Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension
2016
Hallmarks of Cancer: The Next Generation
2011 Standout
Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
2015
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Role of Carcinoma-Associated Fibroblasts and Hypoxia in Tumor Progression
2010
Endosomal Trafficking During Mitosis and Notch-Dependent Asymmetric Division
2018
Proteolytic interstitial cell migration: a five-step process
2009
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize
2006
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Unleashing formins to remodel the actin and microtubule cytoskeletons
2009
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Chemotaxis in cancer
2011
Mechanotransduction gone awry
2008
Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance
2011
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
2008 Standout
Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and -independent collective cancer cell invasion
2011
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model
2008
Blebs lead the way: how to migrate without lamellipodia
2008
The biology and function of fibroblasts in cancer
2016 Standout
Collagen-based cell migration models in vitro and in vivo
2009
The Fourth Transmembrane Segment Forms the Interface of the Dopamine D2 Receptor Homodimer
2003
Rab GTPases as coordinators of vesicle traffic
2009 Standout
Stromal myofibroblasts are drivers of invasive cancer growth
2008
Integrins: masters and slaves of endocytic transport
2009
Fibroblast-mediated drug resistance in cancer
2013
Determinants of leader cells in collective cell migration
2010
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Mechanical modes of ‘amoeboid’ cell migration
2009
G-protein-coupled receptors and signaling networks: emerging paradigms
2001
Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells
2010
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Cancer as an overhealing wound: an old hypothesis revisited
2008 Standout
Cell adhesion: integrating cytoskeletal dynamics and cellular tension
2010 Standout
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
G protein-coupled receptors stimulation and the control of cell migration
2009
Emerging Biological Principles of Metastasis
2017 Standout
Fibroblasts as architects of cancer pathogenesis
2012
Collective cell migration in morphogenesis, regeneration and cancer
2009 Standout
A role for Rho GTPases and cell–cell adhesion in single-cell motility in vivo
2009
Carcinoma-associated fibroblasts provide operational flexibility in metastasis
2014
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
2013
Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
2009
Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
2014
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Mammalian G Proteins and Their Cell Type Specific Functions
2005
The β3-Adrenergic Receptor Activates Mitogen-activated Protein Kinase in Adipocytes through a Gi-dependent Mechanism
1999
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironment
2015
Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis
2009
Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis
2011
The plasticity of cytoskeletal dynamics underlying neoplastic cell migration
2010
LIF Mediates Proinvasive Activation of Stromal Fibroblasts in Cancer
2014
Collective cell migration requires suppression of actomyosin at cell–cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
2010
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells
2012
Random versus directionally persistent cell migration
2009
Secreted Versus Membrane-anchored Collagenases
2009
The role and regulation of blebs in cell migration
2013
The crosstalk between microtubules, actin and membranes shapes cell division
2020
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Clues from cell metabolism
2010 StandoutNatureNobel
Roles of G‐protein‐coupled receptor dimerization
2004
β 2 -Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
1998 StandoutNobel
Tube Travel: The Role of Proteases in Individual and Collective Cancer Cell Invasion
2008
G Protein–Coupled Receptor Oligomerization
2004
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel
2011
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
2006 StandoutNobel
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
FUNCTIONAL AND STRUCTURAL COMPLEXITY OF SIGNAL TRANSDUCTION VIA G-PROTEIN-COUPLED RECEPTORS
1997
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
1998
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Mechanobiology of Macrophages: How Physical Factors Coregulate Macrophage Plasticity and Phagocytosis
2019
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Regulation of the anti-tumour immune response by cancer-associated fibroblasts
2014
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Fibroblast heterogeneity in the cancer wound
2014
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Mechanisms of collective cell migration at a glance
2009
Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis
2011
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Plasticity of cell migration: a multiscale tuning model
2009
Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited
2009
Mechanisms of Endocytosis
2009 Standout
Integrins in cell migration – the actin connection
2008
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia
2009
Activation of fibroblasts in cancer stroma
2010
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel
Works of Robert Grosse being referenced
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation
2007
Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression
2019
Involvement of Gs and Gi Proteins in Dual Coupling of the Luteinizing Hormone Receptor to Adenylyl Cyclase and Phospholipase C
1996
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
2007
Receptor-dependent RhoA Activation in G12/G13-deficient Cells
2003
The Diaphanous-related Formin FHOD1 Associates with ROCK1 and Promotes Src-dependent Plasma Membrane Blebbing
2008
Staying in Shape with Formins
2006
Contribution of receptor/G protein signaling to cell growth and transformation
2000
Integrin Trafficking Regulated by Rab21 Is Necessary for Cytokinesis
2008
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion
2007
Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors
2000
Gα12/13 Is Essential for Directed Cell Migration and Localized Rho-Dia1 Function
2005
Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC
2010
Cell motility through plasma membrane blebbing
2008
Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor
1997
SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility
2007
Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL
2013 Science