Citation Impact
Citing Papers
Little evidence for involvement of MLH3 in colorectal cancer predisposition
2003
Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer.
1999
Mutations within the hMLH1 and hPMS2 Subunits of the Human MutLα Mismatch Repair Factor Affect Its ATPase Activity, but Not Its Ability to Interact with hMutSα
2002
A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype
1998 StandoutNobel
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.
1995
Mutagenesis of yeast MW104-1B strain has identified the uncharacterized PMS6 DNA mismatch repair gene locus and additional alleles of existing PMS1, PMS2 and MSH2 genes
1994
Mismatch repair, genetic stability and tumour avoidance
1995 StandoutNobel
Editing DNA replication and recombination by mismatch repair: from bacterial genetics to mechanisms of predisposition to cancer in humans
1995
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
Differential Requirement for Proliferating Cell Nuclear Antigen in 5′ and 3′ Nick-directed Excision in Human Mismatch Repair
2004
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2
1996 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Requirement of the Yeast MSH3 and MSH6 Genes for MSH2-dependent Genomic Stability
1996
Positional cloning moves from perditional to traditional
1995
Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms
2001
Identification of mismatch repair genes and their role in the development of cancer
1995
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
1995
Lateral gene transfer and the nature of bacterial innovation
2000 StandoutNature
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
MutS homologs in mammalian cells
1997
Pms2 is a genetic enhancer of trinucleotide CAG{middle dot}CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion
2004
A Targeted DNA-PKcs-Null Mutation Reveals DNA-PK-Independent Functions for KU in V(D)J Recombination
1998
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients
1996
Comparative genomics, genome cross-referencing and XREFdb
1995
Identification of a Second MutL DNA Mismatch Repair Complex (hPMS1 and hMLH1) in Human Epithelial Cells
2000
Genetic instabilities in human cancers
1998 StandoutNature
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
ATM: from gene to function
1998
Targeted Disruption of the Catalytic Subunit of the DNA-PK Gene in Mice Confers Severe Combined Immunodeficiency and Radiosensitivity
1998
Corynebacterium diphtheriae spoligotyping based on combined use of two CRISPR loci
2007
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
1995
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
The Hallmarks of Cancer
2000 Standout
Small Slipped Register Genetic Instabilities in Escherichia coli in Triplet Repeat Sequences Associated with Hereditary Neurological Diseases
1998
Trinucleotide repeats associated with human disease
1997
Mismatch repair and cancer susceptibility
1994
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
Molecular Cloning and Functional Analysis of a Human cDNA Encoding an Escherichia Coli AlkB Homolog, a Protein Involved in DNA Alkylation Damage Repair
1996
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
1998 Nature
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
2002 StandoutNatureNobel
Eukaryotic mismatch repair: an update
1998
The Molecular Basis of Turcot's Syndrome
1995
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus
1998
Tumor Microsatellite Instability and Clinical Outcome in Young Patients with Colorectal Cancer
2000
Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites
1998
The extracytoplasmic function sigma factors: role in bacterial pathogenesis
2004
Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer
1997
Replication errors: cha(lle)nging the genome
1998
Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3
1996
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Interactions of anti-sigma factor antagonists of Mycobacterium tuberculosis in the yeast two-hybrid system
2005
Genetic instability in colorectal cancers
1997 StandoutNature
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
M. tuberculosis Ser/Thr Protein Kinase D Phosphorylates an Anti-Anti–Sigma Factor Homolog
2007
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
1994
The Human Mismatch Recognition Complex hMSH2-hMSH6 Functions as a Novel Molecular Switch
1997
Role of DNA mismatch repair in apoptotic responses to therapeutic agents
2004
Genetic predisposition to colorectal cancer
2004
Hereditary Gastrointestinal Polyposis and Nonpolyposis Syndromes
1994
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
1995
An atypical topoisomerase II from archaea with implications for meiotic recombination
1997 Nature
Microsatellite Instability in Human Cancer: A Prognostic Marker for Chemotherapy?
1999
Medical and Societal Consequences of the Human Genome Project
1999
A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells
1995
Cisplatin and Adriamycin Resistance Are Associated with MutLα and Mismatch Repair Deficiency in an Ovarian Tumor Cell Line
1996 StandoutNobel
Mismatch repair: mechanisms and relationship to cancer susceptibility
1995
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Repair of Large Insertion/Deletion Heterologies in Human Nuclear Extracts Is Directed by a 5′ Single-strand Break and Is Independent of the Mismatch Repair System
1999 StandoutNobel
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
DNA mismatch repair and cancer
2001
Meiotic Pachytene Arrest in MLH1-Deficient Mice
1996
Mutation in the Mismatch Repair Gene Msh6 Causes Cancer Susceptibility
1997
Genetic control of microsatellite stability
1997
Mechanism of 5′-Directed Excision in Human Mismatch Repair
2003 StandoutNobel
Identification of hMutLβ, a Heterodimer of hMLH1 and hPMS1
1999
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair
1998
Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma
1996
Mismatch repair defects in human carcinogenesis
1996
DNA damage tolerance, mismatch repair and genome instability
1994
Rapid, accurate, computational discovery of Rho-independent transcription terminators illuminates their relationship to DNA uptake
2007
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
1996
DNA Chain Length Dependence of Formation and Dynamics of hMutSα·hMutLα·Heteroduplex Complexes
2001 StandoutNobel
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
1995
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
1998 StandoutNobel
Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability
2000 StandoutNobel
Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer
2003
Mammalian DNA Mismatch Repair
1999
Microsatellite instability: marker of a mutator phenotype in cancer.
1994
The role of hMLH3 in familial colorectal cancer.
2003
Search and Discovery Strategies for Biotechnology: the Paradigm Shift
2000
APC mutations in colorectal tumors with mismatch repair deficiency.
1996
Mosaic Prophages with Horizontally Acquired Genes Account for the Emergence and Diversification of the Globally Disseminated M1T1 Clone of Streptococcus pyogenes
2005
Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro
1986
Genome-Wide Definition of the SigF Regulon in Mycobacterium tuberculosis
2012
Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro.
1985
hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis.
1999
The Saccharomyces cerevisiae MLH 3 gene functions in MSH3-dependent suppression of frameshift mutations
1998
Loss of Heterozygosity and Base Substitution at the APRT Locus in Mismatch-Repair-Proficient and -Deficient Colorectal Carcinoma Cell Lines
1996
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
Mutations of GTBP in Genetically Unstable Cells
1995 Science
DNA Loop Repair by Human Cell Extracts
1994 Science
Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase
1999 StandoutScienceNobel
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Requirement of the Yeast RTH1 5′ to 3′ Exonuclease for the Stability of Simple Repetitive DNA
1995 Science
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds.
1994
Human MutSα Specifically Binds to DNA Containing Aminofluorene and Acetylaminofluorene Adducts
1996
Functional Genomics Reveals Extended Roles of the Mycobacterium tuberculosis Stress Response Factor σ H
2009
MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast
1994 Science
Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes.
1986
Medical and Ethical Consequences of the Human Genome Project
1991
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage.
1995
Human exonuclease I interacts with the mismatch repair protein hMSH2.
1998
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Mismatch Repair Co-opted by Hypermutation
1998 Science
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.
1995
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.
1996
Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage
1996
Methylator-induced, Mismatch Repair-dependent G2Arrest Is Activated through Chk1 and Chk2
2005
Mismatch repair in extracts of Werner syndrome cell lines.
1997
Binding of Mismatched Microsatellite DNA Sequences by the Human MSH2 Protein
1994 Science
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
2003
Detection of Endogenous Malondialdehyde-Deoxyguanosine Adducts in Human Liver
1994 Science
Functional Studies on the Candidate ATPase Domains of Saccharomyces cerevisiae MutLα
2000
Genetic Dissection of Complex Traits
1994 StandoutScience
Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine
1999
Increased amount of a 25-kilodalton phosphoprotein after v-mos transfection of CHO cells.
1988
Functional Domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA Mismatch Repair Proteins and Their Relevance to Human Hereditary Nonpolyposis Colorectal Cancer-Associated Mutations
1997
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Inhibition by cAMP of Ras-Dependent Activation of Raf
1993 Science
A Role for Exonuclease I from S. pombe in Mutation Avoidance and Mismatch Correction
1995 Science
Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells.
1999
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
The role of DNA mismatch repair in drug resistance.
1998
DNA methylation and genetic instability in colorectal cancer cells
1997
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
2003
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype
1996
Regulation of the SigH stress response regulon by an essential protein kinase in Mycobacterium tuberculosis
2008
Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells
1996
A hPMS2 Mutant Cell Line Is Defective in Strand-specific Mismatch Repair
1995
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.
1994
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions.
1995
Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes
1996 Science
Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli.
1996
Biochemistry and genetics of eukaryotic mismatch repair.
1996
The Saccharomyces cerevisiae Msh2 and Msh6 Proteins Form a Complex That Specifically Binds to Duplex Oligonucleotides Containing Mismatched DNA Base Pairs
1996
Mycobacterium tuberculosis SigF Regulates Genes Encoding Cell Wall-Associated Proteins and Directly Regulates the Transcriptional Regulatory Gene phoY1
2007
The Human Genome Project: Reaching the Finish Line
1998 StandoutScienceNobel
Works of Robert Fleischmann being referenced
Strategies for whole microbial genome sequencing and analysis
1997
Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer
1994 Nature
DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus
1997
Use of the complete genome sequence information of Haemophilus influenzae strain Rd to investigate lipopolysaccharide biosynthesis
1996
Abnormality of insulin binding and receptor phosphorylation in an insulin-resistant melanoma cell line.
1984
Frequency and Distribution of DNA Uptake Signal Sequences in the Haemophilus influenzae Rd Genome
1995 ScienceNobel
DNA-mediated gene transfer of a mutant regulatory subunit of cAMP-dependent protein kinase.
1985
Reduced immunopathology and mortality despite tissue persistence in aMycobacterium tuberculosismutant lacking alternative σ factor, SigH
2002
Attenuation of Late-Stage Disease in Mice Infected bythe Mycobacterium tuberculosis Mutant Lacking theSigF Alternate Sigma Factor and Identification ofSigF-Dependent Genes by MicroarrayAnalysis
2004
Mutation of a mutL Homolog in Hereditary Colon Cancer
1994 Science
Modeling Bacterial Evolution with Comparative-Genome-Based Marker Systems: Application to Mycobacterium tuberculosis Evolution and Pathogenesis
2003
The role of cAMP in regulating tumour cell growth.
1986