Citation Impact
Citing Papers
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
2007
The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity
1997 Standout
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Wildtype Kras2 can inhibit lung carcinogenesis in mice
2001
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
2009 Standout
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
1995 Standout
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
EMT and Dissemination Precede Pancreatic Tumor Formation
2012 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Distinct Mechanisms Mediate the Initial and Sustained Phases of Integrin-mediated Activation of the Raf/MEK/Mitogen-activated Protein Kinase Cascade
1998
Lung Cancer
2008 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
2010 Standout
Cellular Senescence in Cancer and Aging
2007 Standout
Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation
1995 StandoutNobel
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
1994 Nature
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
The Hallmarks of Cancer
2000 Standout
Two Distinct Raf Domains Mediate Interaction with Ras
1995
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
Biochemical evidence that Patched is the Hedgehog receptor
1996 StandoutNature
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine
1996 Standout
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
1996 StandoutNature
Pancreatic Adenocarcinoma
2014 Standout
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
2001 Nature
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
The Ras-related Protein Rheb Is Farnesylated and Antagonizes Ras Signaling and Transformation
1997
The essence of senescence: Figure 1.
2010 Standout
Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation
1999
Integrins Regulate the Linkage between Upstream and Downstream Events in G Protein-coupled Receptor Signaling to Mitogen-activated Protein Kinase
2000
TGFβ in Cancer
2008 Standout
Ceramide Activates the Stress-activated Protein Kinases
1995
Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL
1996 Standout
Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis
2004 Standout
[21] Analysis of Ras protein expression in mammalian cells
1995
cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway
1997 Standout
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
The role of senescent cells in ageing
2014 StandoutNature
The Hallmarks of Aging
2013 Standout
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
2003
Benzodiazepine peptidomimetic inhibitors of farnesyltransferase
1994
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
2001
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Nonfilamentous C. albicans Mutants Are Avirulent
1997 Standout
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1
1997
14-3-3: Modulators of Signaling Proteins?
1994 Science
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response
2008 Nobel
Endogenous expression of Hras G12V induces developmental defects and neoplasms with copy number imbalances of the oncogene
2009
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Integrin Signaling
1999 StandoutScience
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
1997 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function.
1994
Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner
1994
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner
1995
Activation of Raf as a Result of Recruitment to the Plasma Membrane
1994 Science
Cloning and characterization of ECE1, a gene expressed in association with cell elongation of the dimorphic pathogen Candida albicans
1993
Human Homolog of patched , a Candidate Gene for the Basal Cell Nevus Syndrome
1996 StandoutScience
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.
1995
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
2001 StandoutNobel
Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells.
1995
Works of Robert Finney being referenced
Association of pRas and pRaf-1 in a complex correlates with activation of a signal transduction pathway
1993
[32] Ras-Raf complexes: Analyses of complexes formed in Vivo
1995
Predisposition to Neoplastic Transformation Caused by Gene Replacement of H- ras 1
1993 ScienceNobel
The programs of protein synthesis accompanying the establishment of alternative phenotypes in Candida albicans
1985