Citation Impact
Citing Papers
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
2009 Standout
Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker
2012 Standout
Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)
2014 Standout
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
2013 StandoutNobel
Towards AOP application – Implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization
2014
Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models
2016 StandoutNobel
Novel Mechanism for Dehalogenation and Glutathione Conjugation of Dihalogenated Anilines in Human Liver Microsomes: Evidence foripsoGlutathione Addition
2011
Preparation of human metabolites of propranolol using laboratory‐evolved bacterial cytochromes P450
2005 StandoutNobel
Phloroglucinol compounds of natural origin
2006 Standout
Drug-Induced Hepatotoxicity
2003 Standout
Identification of sulfation sites of metabolites and prediction of the compounds’ biological effects
2006
Comparison of random mutagenesis and semi-rational designed libraries for improved cytochrome P450 BM3-catalyzed hydroxylation of small alkanes
2012 StandoutNobel
Selective C H bond functionalization with engineered heme proteins: new tools to generate complexity
2018 StandoutNobel
Using carbon dioxide as a building block in organic synthesis
2015 Standout
Drug discovery for a new generation of covalent drugs
2012
Site‐Selective Labeling of a Lysine Residue in Human Serum Albumin
2014
Organocatalytic Asymmetric Hydrolysis of Epoxides
2014 StandoutNobel
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Complex reactions catalyzed by cytochrome P450 enzymes
2006
Mammalian aldehyde oxidases: genetics, evolution and biochemistry
2007
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety
2014 Standout
Herbal bioactivation: The good, the bad and the ugly
2003
Expanding P450 catalytic reaction space through evolution and engineering
2014 StandoutNobel
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Biological effects of essential oils – A review
2007 Standout
Recent advances in the study on capsaicinoids and capsinoids
2010 Standout
Ruthenium‐Catalyzed Direct Methylation of Primary and Secondary Aromatic Amines Using Carbon Dioxide and Molecular Hydrogen
2013
Jensenone: Biological Reactivity of a Marsupial Antifeedant from Eucalyptus
2004
Capsaicin Induces Heme Oxygenase-1 Expression in HepG2 Cells Via Activation of PI3K-Nrf2 Signaling: NAD(P)H:Quinone Oxidoreductase as a Potential Target
2007
Iron Catalysis in Organic Synthesis
2015 Standout
Structural Elucidation and Quantification of Phenolic Conjugates Present in Human Urine after Tea Intake
2012
Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3
2006 StandoutNobel
Targeted Covalent Inhibitors for Drug Design
2016
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Copper Active Sites in Biology
2014 Standout
Recent Advances in Transition Metal Catalyzed Oxidation of Organic Substrates with Molecular Oxygen
2005 Standout
Organokatalytische asymmetrische Hydrolyse von Epoxiden
2014 StandoutNobel
Chemistry and Biochemistry of Dietary Polyphenols
2010 Standout
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity
2001
Formation and Cleavage of C–C Bonds by Enzymatic Oxidation–Reduction Reactions
2018
Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently
2019
Sustainable Conversion of Carbon Dioxide: An Integrated Review of Catalysis and Life Cycle Assessment
2017 Standout
Determination of Capsaicinoids in Habanero Peppers by Chemometric Analysis of UV Spectral Data
2007
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
The resurgence of covalent drugs
2011
Application of Stable Isotope-Labeled Compounds in Metabolism and in Metabolism-Mediated Toxicity Studies
2008
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development
2014 StandoutNobel
The Mononuclear Molybdenum Enzymes
2014 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Detection and characterization of a glutathione conjugate of a novel copper complex.
2009
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Palladium‐Catalyzed Fluorosulfonylvinylation of Organic Iodides
2017 StandoutNobel
Palladium‐Catalyzed Fluorosulfonylvinylation of Organic Iodides
2017 StandoutNobel
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far
2013 Standout
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
2013 StandoutNobel
The Essential Medicinal Chemistry of Curcumin
2017 Standout
Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology
2012 Standout
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Ruthenium‐Catalyzed Direct Methylation of Primary and Secondary Aromatic Amines Using Carbon Dioxide and Molecular Hydrogen
2013
Proton-Coupled Electron Transfer
2012 Standout
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of Robert Espina being referenced
Application of Quantitative NMR in Pharmacological Evaluation of Biologically Generated Metabolites: Implications in Drug Discovery
2010
Characterization of HKI-272 Covalent Binding to Human Serum Albumin
2010
Species-Specific, P450- and Sulfotransferase-Mediated Novel Ring Contraction of a Naphthyridine-N-Oxide Compound in Cynomolgus Monkey
2007
Bioactivation of Benzylamine to Reactive Intermediates in Rodents: Formation of Glutathione, Glutamate, and Peptide Conjugates
2002
Delineating Novel Metabolic Pathways of DPC 963, a Non-Nucleoside Reverse Transcriptase Inhibitor, in Rats. Characterization of Glutathione Conjugates of Postulated Oxirene and Benzoquinone Imine Intermediates by LC/MS and LC/NMR
2002
Disposition of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘- (methylsulfonyl)-[1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)- 1H-pyrazole-5-carboxamide (DPC 423) by Novel Metabolic Pathways. Characterization of Unusual Metabolites by Liquid Chromatography/Mass Spectrometry and NMR
2001
Alternate Strategies to Obtain Mass Balance without the Use of Radiolabeled Compounds: Application of Quantitative Fluorine (19F) Nuclear Magnetic Resonance (NMR) Spectroscopy in Metabolism Studies
2012
Disposition of Glutathione Conjugates in Rats by a Novel Glutamic Acid Pathway: Characterization of Unique Peptide Conjugates by Liquid Chromatography/Mass Spectrometry and Liquid Chromatography/NMR
2000
Characterization of Novel Glutathione Adducts of a Non-Nucleoside Reverse Transcriptase Inhibitor, (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3,4-dihydro-2(1H)-quinazolinone (DPC 961), in Rats. Possible Formation of an Oxirene Metabolic Intermediate from a Disubstituted Alkyne
2000
Metabolism of Capsaicin by Cytochrome P450 Produces Novel Dehydrogenated Metabolites and Decreases Cytotoxicity to Lung and Liver Cells
2003
P450-Mediated Metabolism of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole- 5-carboxamide (DPC 423) and Its Analogues to Aldoximes. Characterization of Glutathione Conjugates of Postulated Intermediates Derived from Aldoximes
2001
Formation of unusual glutamate conjugates of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC 423) and its analogs: the role of gamma-glutamyltranspeptidase in the biotransformation of benzylamines.
2001