Citation Impact
Citing Papers
MicroRNA-155 is induced during the macrophage inflammatory response
2007 StandoutNobel
edgeR : a Bioconductor package for differential expression analysis of digital gene expression data
2009 Standout
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway
2002 Standout
Regulation of tyrosine hydroxylase promoter activity by the von Hippel–Lindau tumor suppressor protein and hypoxia‐inducible transcription factors
2003
Gene ontology analysis for RNA-seq: accounting for selection bias
2010 Standout
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
Adrenalectomy for Familial Pheochromocytoma in the Laparoscopic Era
2002
Quality of Life and Satisfaction with Outcome among Prostate-Cancer Survivors
2008 Standout
Surgical management of brainstem hemangioblastomas in patients with von Hippel—Lindau disease
2003
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
2006 Standout
Pheochromocytomas in von Hippel-Lindau Syndrome and Multiple Endocrine Neoplasia Type 2 Display Distinct Biochemical and Clinical Phenotypes
2001
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Histopathology and Molecular Genetics of Multiple Cysts and Microcystic (Serous) Adenomas of the Pancreas in von Hippel-Lindau Patients
2000
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
Allelic losses on chromosome arm 10q and mutation of the PTEN ( MMAC1 ) tumour suppressor gene in primary and metastatic malignant melanomas
2000
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Reduced Expression of PTEN Protein and Its Prognostic Implications in Invasive Ductal Carcinoma of the Breast
2005
p63 Is a Prostate Basal Cell Marker and Is Required for Prostate Development
2000
Immunology and immunotherapy approaches for prostate cancer
2007
Phaeochromocytoma
2005 Standout
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
2011 Standout
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Tenets of PTEN Tumor Suppression
2008
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Molecular determinants of resistance to antiandrogen therapy
2003 Standout
Increased AKT Activity Contributes to Prostate Cancer Progression by Dramatically Accelerating Prostate Tumor Growth and Diminishing p27Kip1 Expression
2000
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
2003 Standout
The development of androgen-independent prostate cancer
2001 Standout
Organoid culture systems for prostate epithelial and cancer tissue
2016
Chromosomal aberrations in prostate cancer xenografts detected by comparative genomic hybridization
2002
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
von Hippel-Lindau disease
2003 Standout
A loss-of-function RNA interference screen for molecular targets in cancer
2006 Nature
Inhibition of Egr-1 expression reverses transformation of prostate cancer cells in vitro and in vivo
2003
PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma
2000
Epigenetic PTEN Silencing in Malignant Melanomas without PTEN Mutation
2000
Molecular genetics of prostate cancer
2000
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Molecular genetics of pancreatic intraepithelial neoplasia
2007
Gene Structure and Transcriptional Regulation of Human Gal β1,4(3) GlcNAc α2,3-Sialyltransferase VI (hST3Gal VI) Gene in Prostate Cancer Cell Line
2001
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
1999
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
2012
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
2010
The 1999 patterns of care study of radiotherapy in localized prostate carcinoma
2003
Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma
2003
Pheochromocytoma: The Expanding Genetic Differential Diagnosis
2003
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Pancreatic Cancer
2010 Standout
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
2003
Clinical and genetic analysis of patients with pancreatic neuroendocrine tumors associated with von Hippel-Lindau disease
2000
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
American Cancer Society Guideline for the Early Detection of Prostate Cancer: Update 2010
2010
Immunotherapy for pancreatic cancer — science driving clinical progress
2005
Tumor Suppressor PTEN Mediates Sensing of Chemoattractant Gradients
2002
Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth
2003
Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma
1996
Human cancer, PTEN and the PI-3 kinase pathway
2004
Pten Dose Dictates Cancer Progression in the Prostate
2003
Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines
1999 Standout
Central nervous system hemangioblastomas, endolymphatic sac tumors, and von Hippel-Lindau disease
2000
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Interaction of the Tumor Suppressor PTEN/MMAC with a PDZ Domain of MAGI3, a Novel Membrane-associated Guanylate Kinase
2000 Standout
Glycoproteomics-Based Identification of Cancer Biomarkers
2011
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Adenovirus-mediated transfer of inducible caspases: a novel "death switch" gene therapeutic approach to prostate cancer.
2001
PERCUTANEOUS RENAL CRYOABLATION OF RENAL TUMORS IN PATIENTS WITH VON HIPPEL-LINDAU DISEASE
2002
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
2009
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase
1999 StandoutScienceNobel
Health Related Quality of Life Patterns in Patients Treated With Interstitial Prostate Brachytherapy for Localized Prostate Cancer—Data From CaPSURE
2003
Caveolin-1 Maintains Activated Akt in Prostate CancerCells through Scaffolding Domain Binding Site Interactions with andInhibition of Serine/Threonine Protein Phosphatases PP1 andPP2A
2003
QUALITY OF LIFE AFTER TREATMENT FOR LOCALIZED PROSTATE CANCER: DIFFERENCES BASED ON TREATMENT MODALITY
2001
The Impact of Open Radical Retropubic Prostatectomy on Continence and Lower Urinary Tract Symptoms: A Prospective Assessment Using Validated Self-Administered Outcome Instruments
2004
Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients.
1996
RENAL CANCER IN FAMILIES WITH HEREDITARY RENAL CANCER: PROSPECTIVE ANALYSIS OF A TUMOR SIZE THRESHOLD FOR RENAL PARENCHYMAL SPARING SURGERY
1999
Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: The MPAKT model
2003
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
2001
Pten is essential for embryonic development and tumour suppression
1998 Standout
The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway
2004
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.
1994
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals
2002 StandoutNobel
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.
1999
Determination of tag density required for digital transcriptome analysis: Application to an androgen-sensitive prostate cancer model
2008
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
2001
Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice.
2001
LAPAROSCOPIC PARTIAL ADRENALECTOMY IN PATIENTS WITH HEREDITARY FORMS OF PHEOCHROMOCYTOMA
2000
Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten
1999
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Comprehensive Comparison of Health-Related Quality of Life After Contemporary Therapies for Localized Prostate Cancer
2002
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
1998
Retinal hemangioblastoma in von Hippel-Lindau disease: a clinical and molecular study.
2002
Nephron Sparing Surgery for Renal Cell Carcinoma and von Hippel-Lindau’s Disease: A Single Center Experience
2003
Allelic imbalance and mutations of thePTEN gene in ovarian cancer
2000
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen.
2001
PREVALENCE, MORPHOLOGY AND BIOLOGY OF RENAL CELL CARCINOMA IN VON HIPPEL-LINDAU DISEASE COMPARED TO SPORADIC RENAL CELL CARCINOMA
1998
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
1998
Von Hippel-Lindau Syndrome
1999
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Effects of DNA methylation on topoisomerase I and II cleavage activities.
1994 StandoutNobel
Large-scale analysis of the human and mouse transcriptomes
2002 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Surgical Management of Multi-Organ Visceral Tumors In Patients With Von Hippel-Lindau Disease: A Single Stage Approach
2003
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.
1999
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Pancreatic Cancer
2008
Pheochromocytomas and Paragangliomas in von Hippel–Lindau Disease
2002
Recent Advances in Genetics, Diagnosis, Localization, and Treatment of Pheochromocytoma
2001
Comparison of MR/Ultrasound Fusion–Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer
2015 Standout
Chemical Glycoproteomics
2016 StandoutNobel
Works of Robert E. Reiter being referenced
Chromosome 17p deletions and p53 mutations in renal cell carcinoma.
1993
Transcriptional programs activated by exposure of human prostate cancer cells to androgen
2002
The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking status
2008
Human prostate sphere‐forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo
2009
Value of Targeted Prostate Biopsy Using Magnetic Resonance–Ultrasound Fusion in Men with Prior Negative Biopsy and Elevated Prostate-specific Antigen
2013
Role of prostate stem cell antigen in prostate cancer research
2002
Stem Cell Genes in Androgen-independent Prostate Cancer
1998
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice
1997
Prostate Stem Cell Antigen Is a Putative Target for Immunotherapy in Pancreatic Cancer
2005
Survivorship Beyond Convalescence: 48-Month Quality-of-Life Outcomes After Treatment for Localized Prostate Cancer
2009
Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process.
1999
Original Articles: Kidney Cancer: Parenchymal Sparing Surgery in Patients With Hereditary Renal Cell Carcinoma
1995
LOW P27 EXPRESSION PREDICTS POOR DISEASE-FREE SURVIVAL IN PATIENTS WITH PROSTATE CANCER
1998
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
1998
Prostate Stem Cell Antigen Is Overexpressed in Prostate Cancer Metastases
2005
Original Articles
1995
Low p27 expression predicts poor disease-free survival in patients with prostate cancer.
1998
Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma.
2001
QUALITY OF LIFE OUTCOMES AFTER BRACHYTHERAPY FOR EARLY STAGE PROSTATE CANCER
2000
Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer
1998
CLINICAL AND GENETIC CHARACTERIZATION OF PHEOCHROMOCYTOMA IN VON HIPPEL-LINDAU FAMILIES: COMPARISON WITH SPORADIC PHEOCHROMOCYTOMA GIVES INSIGHT INTO NATURAL HISTORY OF PHEOCHROMOCYTOMA
1999
Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors.
1993