Citation Impact
Citing Papers
Krüppel-like Factor-6 Promotes Preadipocyte Differentiation through Histone Deacetylase 3-dependent Repression of DLK1
2005
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1996 StandoutNobel
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.
1996
PDX-1/VP16 Fusion Protein, Together With NeuroD or Ngn3, Markedly Induces Insulin Gene Transcription and Ameliorates Glucose Tolerance
2005
Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor α Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein β
2001
Hallmarks of Cancer: The Next Generation
2011 Standout
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
2007
Regulation by glucocorticoids of angiotensinogen gene expression and secretion in adipose cells
1997
The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein–ubiquitin ligase SCFSkp2
2002
Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α
2005
Palmitate-Activated Macrophages Confer Insulin Resistance to Muscle Cells by a Mechanism Involving Protein Kinase C θ and ε
2011
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
1993 StandoutNature
Cytokine production by islets in health and diabetes: cellular origin, regulation and function
2010
Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects
2016
mTOR Signaling in Growth Control and Disease
2012 Standout
Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes
2006
Inflammation and metabolic disorders
2006 StandoutNature
The retinoblastoma gene family in differentiation and development
1999
E2Fs Regulate Adipocyte Differentiation
2002
Inflammatory links between obesity and metabolic disease
2011 Standout
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
Role of PPARγ in Regulating a Cascade Expression of Cyclin-dependent Kinase Inhibitors, p18(INK4c) and p21(Waf1/Cip1), during Adipogenesis
1999
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
1997 StandoutNature
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Activation of Wnt/β-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells
2009
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
Fat tissue, aging, and cellular senescence
2010
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Hedgehog signaling plays a conserved role in inhibiting fat formation
2006
Desnutrin, an Adipocyte Gene Encoding a Novel Patatin Domain-containing Protein, Is Induced by Fasting and Glucocorticoids
2004
Insulin-promoter-factor 1 is required for pancreas development in mice
1994 StandoutNature
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Modulating the transcriptional control of adipogenesis
1997
Cdk4 promotes adipogenesis through PPARγ activation
2005
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance
2015
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Stimulation of 3T3-L1 Adipogenesis by Signal Transducer and Activator of Transcription 5
2002
The Large Subunit of the DNA Replication Complex C (DSEB/RF-C140) Cleaved and Inactivated by Caspase-3 (CPP32/YAMA) during Fas-induced Apoptosis
1997
Relation of depot-specific adipose inflammation to insulin resistance in human obesity
2012
Rapamycin‐sensitive phase of 3T3‐L1 preadipocyte differentiation after clonal expansion
2001
The large subunit of replication factor C is a substrate for caspase-3 invitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis
1997
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
2020
Pancreatic Homeodomain Transcription Factor IDX1/IPF1 Expressed in Developing Brain Regulates Somatostatin Gene Transcription in Embryonic Neural Cells
2000
Gene regulatory factors in pancreatic development
2003
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
2008 StandoutNature
Adipose Development: From Stem Cell to Adipocyte
2005
Direct Binding of Activated c-Src to the β3-Adrenergic Receptor Is Required for MAP Kinase Activation
2000 StandoutNobel
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Specific Inhibitors of p38 Mitogen-activated Protein Kinase Block 3T3-L1 Adipogenesis
1998
S-Nitrosylation-dependent Inactivation of Akt/Protein Kinase B in Insulin Resistance
2005
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
2000
Insulin Resistance is Associated with MCP1-Mediated Macrophage Accumulation in Skeletal Muscle in Mice and Humans
2014
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
1997 Standout
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
2005
Regulation of signal transducers and activators of transcription (STATs) by effectors of adipogenesis: coordinate regulation of STATs 1, 5A, and 5B with peroxisome proliferator-activated receptor-γ and C/AAAT enhancer binding protein-α
1999
Co-expression of renin-angiotensin system genes in human adipose tissue
1999
Molecular mechanisms of cancer development in obesity
2011
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
2005
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
The hormone resistin links obesity to diabetes
2001 StandoutNature
Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha.
1996
Adipocyte differentiation from the inside out
2006 Standout
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
2014
Peroxisome Proliferator Activated Receptor γ, CCAAT/ Enhancer-binding Protein α, and Cell Cycle Status Regulate the Commitment to Adipocyte Differentiation
1997
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11
1995 StandoutNatureNobel
Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: Functional and physical association with the adipogenic transcription factor C/EBPα
1998
Adipogenesis: forces that tip the scales
2002
Alterations in the TGFβ signaling pathway in myogenic progenitors with age
2004
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
A Nuclear Receptor Atlas: 3T3-L1 Adipogenesis
2005
Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone
2003
Krox20 stimulates adipogenesis via C/EBPβ-dependent and -independent mechanisms
2005
Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle
2007
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis
2003
Developmental Origin of Fat: Tracking Obesity to Its Source
2007
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance
2016
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity
2003 StandoutNobel
Skeletal muscle satellite cells can spontaneously enter an alternative mesenchymal pathway
2004
Pro‐Inflammatory macrophages increase in skeletal muscle of high fat‐Fed mice and correlate with metabolic risk markers in humans
2013
C/EBPβ, When Expressed from the C/ebpα Gene Locus, Can Functionally Replace C/EBPα in Liver but Not in Adipose Tissue
2000
Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle
2009
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
1998
Developmental biology of the pancreas
1995
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
2006
Transcriptional regulation of adipogenesis
2000 Standout
Skeletal Muscle Satellite Cells Are Committed to Myogenesis and Do Not Spontaneously Adopt Nonmyogenic Fates
2011
Differential Roles of Insulin Receptor Substrates in Brown Adipocyte Differentiation
2004
A novel cis-acting element controlling the rat CYP2D5 gene and requiring cooperativity between C/EBP beta and an Sp1 factor.
1994
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
1996
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome
2001 StandoutScience
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Immune Regulation in Obesity-Associated Adipose Inflammation
2013
Metabolically healthy obesity: facts and fantasies
2019
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
2001 StandoutScience
Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes
2001
Inhibition of Adipogenesis by Wnt Signaling
2000 StandoutScience
Understanding Adipocyte Differentiation
1998 Standout
Reduced Adipose Tissue Oxygenation in Human Obesity
2008
Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation
2010
Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects
2014
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity
2006
Cellularity and Adipogenic Profile of the Abdominal Subcutaneous Adipose Tissue From Obese Adolescents: Association With Insulin Resistance and Hepatic Steatosis
2010
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Activation of Peroxisome Proliferator-activated Receptor γ Bypasses the Function of the Retinoblastoma Protein in Adipocyte Differentiation
1999
Early B-Cell Factor (O/E-1) Is a Promoter of Adipogenesis and Involved in Control of Genes Important for Terminal Adipocyte Differentiation
2002
Hepatocyte Nuclear Factor 3β is Involved in Pancreatic β-Cell-Specific Transcription of the pdx-1 Gene
1997
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6
1994 StandoutScience
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Tumor necrosis factor-induced c-myc expression in the absence of mitogenesis is associated with inhibition of adipocyte differentiation.
1993
Regulation of metabolism by the innate immune system
2015
Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients
2000 Standout
Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
2010
Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.
1993
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
2004 StandoutScience
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.
1992
Gene duplications and the origins of vertebrate development
1994
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Stress-Induced Binding of the Transcription Factor CHOP to a Novel DNA Control Element
1996
TNFα-Mediated Inhibition and Reversal of Adipocyte Differentiation Is Accompanied by Suppressed Expression of PPARγ without Effects on Pref-1 Expression*
1997
Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells.
1998
Inhibition of Adipogenesis Through MAP Kinase-Mediated Phosphorylation of PPARγ
1996 Science
Molecular Regulation of Adipogenesis
2000
Control of adipocyte differentiation
1995
Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance
2009
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
2003 StandoutScience
Caspases: Enemies Within
1998 StandoutScience
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
1996 StandoutScience
β-Catenin Interacts with MyoD and Regulates Its Transcription Activity
2008
Transcriptional repression of the C/EBP-alpha and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Regulations is coordinate and independent of protein synthesis.
1992
Works of Robert E. McGehee being referenced
Differentiation-specific element: a cis-acting developmental switch required for the sustained transcriptional expression of the angiotensinogen gene during hormonal-induced differentiation of 3T3-L1 fibroblasts to adipocytes.
1993
p130/p107 expression distinguishes adipogenic potential in primary myoblasts based on age
2002
TNFα Disrupts Mitotic Clonal Expansion and Regulation of Retinoblastoma Proteins p130 and p107 during 3T3-L1 Adipocyte Differentiation
1998
Early expression of p107 is associated with 3T3-L1 adipocyte differentiation
2002
Proteasomal Degradation of Retinoblastoma-Related p130 during Adipocyte Differentiation
2002
Pioglitazone induces apoptosis of macrophages in human adipose tissue
2006
Developmental Profile of Homeobox Gene Expression during 3T3-L1 Adipogenesis
1997
Microarray analysis of differentiation-specific gene expression during 3T3-L1 adipogenesis
2004
Antisense Oligonucleotides to Differentiation-Specific Element Binding Protein (DSEB) mRNA Inhibit Adipocyte Differentiation
1996
Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action
2009
Molecular regulation of adipocyte differentiation
1999
Antisense Suppression of p107 Inhibits 3T3-L1 Adipocyte Differentiation
2001
Regulation and Expression of Retinoblastoma Proteins p107 and p130 during 3T3-L1 Adipocyte Differentiation
1997
Adipose Tissue Extracellular Matrix and Vascular Abnormalities in Obesity and Insulin Resistance
2011
Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP).
1992
Expression of CD68 and Macrophage Chemoattractant Protein-1 Genes in Human Adipose and Muscle Tissues
2005
Stearoyl-Coenzyme A Desaturase 1 Gene Expression Increases after Pioglitazone Treatment and Is Associated with Peroxisomal Proliferator-Activated Receptor-γ Responsiveness
2008
Thrombospondin-1 Is an Adipokine Associated With Obesity, Adipose Inflammation, and Insulin Resistance
2007
Lipin Expression Is Attenuated in Adipose Tissue of Insulin-Resistant Human Subjects and Increases With Peroxisome Proliferator–Activated Receptor γ Activation
2006
Association of Scavenger Receptors in Adipose Tissue With Insulin Resistance in Nondiabetic Humans
2009
IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene.
1994
Differentiation-specific element binding protein (DSEB) binds to a defined element in the promoter of the angiotensinogen gene required for the irreversible induction of gene expression during differentiation of 3T3-L1 adipoblasts to adipocytes.
1995
Differentiation-specific element: a cis-acting developmental switch required for the sustained transcriptional expression of the angiotensinogen gene during hormonal-induced differentiation of 3T3-L1 fibroblasts to adipocytes
1993
Activation of an adipogenic program in adult myoblasts with age
2002
Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance
2013
Human Visfatin Expression: Relationship to Insulin Sensitivity, Intramyocellular Lipids, and Inflammation
2006
Wnt10b Deficiency Promotes Coexpression of Myogenic and Adipogenic Programs in Myoblasts
2005