Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase
2012 Science
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
2016 Science
Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein
2014
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
A polymorphism of the interleukin-1 β gene influences survival in pancreatic cancer
2000
Glutamate receptor ion channels
2005 Standout
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
AMPK signalling in health and disease
2017
Abiotic Stress Signaling and Responses in Plants
2016 Standout
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) Effect on Glucose Production, but Not Energy Metabolism, Is Independent of Hepatic AMPK in Vivo
2014
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
2014
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
2010
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction
2015
β3 and Atypical β‐Adrenoceptors
1993
Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase
2015
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
2009
Modulation of Protein–Protein Interactions with Small Organic Molecules
2003
Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Molecular and cellular mechanisms of general anaesthesia
1994 StandoutNature
Which molecular targets are most relevant to general anaesthesia?
1998
A stable near IR switchable electrochromic polymer based on an indole-substituted nickel dithiolene
2009
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
In vivo genetics of anaesthetic action
2002
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
2017
Mitochondria: In Sickness and in Health
2012 Standout
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Mechanically Activated Ion Channels
2015 StandoutNobel
Halogen Atoms in the Modern Medicinal Chemistry: Hints for the Drug Design
2010
Anesthesiology
1997 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
AMPK at the Nexus of Energetics and Aging
2014
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs
2015
Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth
2008
The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
2009
Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels
2014
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice
2010
Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
2011
AMPK activation: a therapeutic target for type 2 diabetes?
2014
Structural Basis for the Inhibition of Firefly Luciferase by a General Anesthetic
1998
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
2013
Structural basis of AMPK regulation by small molecule activators
2013
Inflammation and cancer: back to Virchow?
2001 Standout
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
2010
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet
2017
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The Hallmarks of Aging
2013 Standout
The endothelin axis: emerging role in cancer
2003
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity
2011
In vitro networks: subcortical mechanisms of anaesthetic action
2002
Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
2016
Arousal in Drosophila
2003
Structure of mammalian AMPK and its regulation by ADP
2011 Nature
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
AMPK as a Pro-longevity Target
2016
A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis
2014
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
2008
Structural basis for high‐affinity volatile anesthetic binding in a natural 4‐helix bundle protein
2005
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
AMP-Activated Protein Kinase Induces p53 by Phosphorylating MDMX and Inhibiting Its Activity
2013
Treatment of nonalcoholic fatty liver disease: role of AMPK
2016
A facile one-pot synthesis of thioethers using heteropoly acids
2007
2016
Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol
2019 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Strategien zur Modulation von Protein‐Protein‐Wechselwirkungen mit synthetischen Substanzen
2005
Recent Advances in Polyoxometalate-Catalyzed Reactions
2015 Standout
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Model Organisms: New Insights Into Ion Channel and Transporter Function. Stomatin homologues interact inCaenorhabditis elegans
2001
A Bioorthogonal Quadricyclane Ligation
2011 StandoutNobel
Cancer Genome Landscapes
2013 StandoutScience
Evidence for a Common Binding Cavity for Three General Anesthetics within the GABAAReceptor
2001
Autophagy and Metabolism
2010 StandoutScience
The Halogen Bond
2016 Standout
Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators
2015
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
2012
Calcineurin Pathway Is Required for Endothelin-1–Mediated Protection Against Oxidant Stress–Induced Apoptosis in Cardiac Myocytes
2001
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Works of Robert Dickinson being referenced
Competitive Inhibition at the Glycine Site of the N -Methyl-d-aspartate Receptor by the Anesthetics Xenon and Isoflurane
2007
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
2006
Determinants of the Anesthetic Sensitivity of Two-pore Domain Acid-sensitive Potassium Channels
2007
Probing the molecular dimensions of general anaesthetic target sites in tadpoles (Xenopus laevis) and model systems using cycloalcohols
1991
Contrasting Synaptic Actions of the Inhalational General Anesthetics Isoflurane and Xenon
2000
Thermodynamics of anesthetic/protein interactions. Temperature studies on firefly luciferase
1993
Can the stereoselective effects of the anesthetic isoflurane be accounted for by lipid solubility?
1994
Stereoselective Loss of Righting Reflex in Rats by Isoflurane
2000
Endothelin attenuates apoptosis in human smooth muscle cells
1997
Discovery of Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 4. Structure−Activity Relationship of Substituents on the Benzene Ring of the Cinnamide
2001