Standout Papers
Citation Impact
Citing Papers
Lipid Rafts As a Membrane-Organizing Principle
2009 StandoutScience
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles
2005
Distinct Mechanisms of Clathrin-independent Endocytosis Have Unique Sphingolipid Requirements
2006
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Essential Role for Caspase-8 in Transcription-independent Apoptosis Triggered by p53
2000
Hallmarks of Cancer: The Next Generation
2011 Standout
Pemphigus Vulgaris IgG-induced Desmoglein-3 Endocytosis and Desmosomal Disassembly Are Mediated by a Clathrin- and Dynamin-independent Mechanism
2008
The DNA-damage response in human biology and disease
2009 StandoutNature
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
2003
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
1999 StandoutNature
Resident vascular progenitor cells: An emerging role for non-terminally differentiated vessel-resident cells in vascular biology
2008
Deoxycholate induces mitochondrial oxidative stress and activates NF- B through multiple mechanisms in HCT-116 colon epithelial cells
2006
The multiple faces of caveolae
2007
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene.
1997
Death Signal-induced Localization of p53 Protein to Mitochondria
2000
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture)
2006
Cell-cycle checkpoints and cancer
2004 StandoutNature
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
P53 Mediates the Apoptotic Response to GTP Depletion after Renal Ischemia-Reperfusion
2003
Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids (Review)
2006
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Pathways of clathrin-independent endocytosis
2007
Autophagy regulates lipid metabolism
2009 StandoutNature
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium–derived factor
2002 Standout
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
2013
Delivery and Expression of Fluid Shear Stress-Inducible Promoters to the Vessel Wall: Applications for Cardiovascular Gene Therapy
1999
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
PUMA, a Novel Proapoptotic Gene, Is Induced by p53
2001 Standout
The p53 pathway and apoptosis
1999
Circulating Endothelial Progenitor Cells Are Reduced in Peripheral Vascular Complications of Type 2 Diabetes Mellitus
2005
The changing landscape of atherosclerosis
2021 StandoutNature
Apoptosis regulators and their role in tumorigenesis
2001
E6 and E7 Gene Silencing and Transformed Phenotype of Human Papillomavirus 16-Positive Oropharyngeal Cancer Cells
2009
CD40 Ligation Induces Tissue Factor Expression in Human Vascular Smooth Muscle Cells
2000
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
DNA damage, p53, apoptosis and vascular disease
2007
Increased ubiquitin immunoreactivity in unstable atherosclerotic plaques associated with acute coronary syndromes
2002 StandoutNobel
The Bile Acid Tauroursodeoxycholic Acid Modulates Phosphorylation and Translocation of Bad via Phosphatidylinositol 3-Kinase in Glutamate-Induced Apoptosis of Rat Cortical Neurons
2004
Regulation and function of the p53 tumor suppressor protein
2001
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
High‐Resolution 3D Quantitative Analysis of Caveolar Ultrastructure and Caveola–Cytoskeleton Interactions
2008
Regulation of death receptor-mediated apoptosis pathways
2000
p53 Induces Apoptosis by Caspase Activation through Mitochondrial Cytochrome c Release
2000
p53
2000
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo.
1997
Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics
2016
Expression of Caveolin-1 Enhances Cholesterol Efflux in Hepatic Cells
2004
Caveolin Regulates Endocytosis of the Muscle Repair Protein, Dysferlin
2007
Cholesterol Substitution Increases the Structural Heterogeneity of Caveolae
2008
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
2005
NF-κB: pivotal mediator or innocent bystander in atherogenesis?
2001
Stabilization of atherosclerotic plaques: New mechanisms and clinical targets
2002
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
2001
Contribution of Myeloperoxidase to Smoking-dependent Vascular Inflammation
2008
A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function
2001
Virus Entry: Open Sesame
2006
Live or let die: the cell's response to p53
2002 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Death and anti-death: tumour resistance to apoptosis
2002 Standout
Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae
2005 Nature
Inflammation in atherosclerosis
2002 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Regulation ofp53downstream genes
1998
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
2005 Nature
p53's Believe It or Not: Lessons on Transcription-Independent Death
2003
The Hallmarks of Aging
2013 Standout
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Atherosclerosis
2000 StandoutNature
Phosphate-enhanced transfection of cationic lipid-complexed mRNA and plasmid DNA
1998 StandoutNobel
Lipid droplets: a unified view of a dynamic organelle
2006
The p53 pathway: positive and negative feedback loops
2005 Standout
Drug Insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis
2006
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Restoration of p53 expression sensitizes human papillomavirus type 16 immortalized human keratinocytes to CD95-mediated apoptosis
2002 StandoutNobel
Biochemical Evidence of Atherosclerosis Progression Mediated by Increased Oxidative Stress in Apolipoprotein E–Deficient Spontaneously Hyperlipidemic Mice Exposed to Chronic Cigarette Smoke
2009
The cellular response to p53: the decision between life and death
1999
Organelle-specific initiation of cell death pathways
2001
Endothelial Progenitor Cells and Vascular Biology in Diabetes Mellitus: Current Knowledge and Future Perspectives
2005
Reactive Species-Mediated Regulation of Cell Signaling and the Cell Cycle: The Role of MAPK
2005
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
Regulation of p53 Function
2001
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells.
2002
p53 and Ceramide as Collaborators in the Stress Response
2013
Transcriptional neoteny in the human brain
2009 StandoutNobel
Targeted inactivation of sister of P-glycoprotein gene ( spgp ) in mice results in nonprogressive but persistent intrahepatic cholestasis
2001
The subendothelial extracellular matrix modulates NF-κB activation by flow
2005
Activation and activities of the p53 tumour suppressor protein
2001
Vascular Endothelial Cells and Smooth Muscle Cells Differ in Expression of Fas and Fas Ligand and in Sensitivity to Fas Ligand–Induced Cell Death
2000
Apaf-1 and Caspase-9 in p53-Dependent Apoptosis and Tumor Inhibition
1999 Science
DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector
1998
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas
2000
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Surfing the p53 network
2000 StandoutNature
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Apoptosis - the p53 network
2003
Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall
2004
Computational Alanine Scanning To Probe Protein−Protein Interactions: A Novel Approach To Evaluate Binding Free Energies
1999
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Endothelial Progenitor Cells
2004 Standout
Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses
2006
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Inhibition of caveolar uptake, SV40 infection, and β1-integrin signaling by a nonnatural glycosphingolipid stereoisomer
2007
Cellular stress response and apoptosis in cancer therapy
2001
Combined Angiogenic and Osteogenic Factor Delivery Enhances Bone Marrow Stromal Cell-Driven Bone Regeneration
2005
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes
2014 Standout
Noncytopathic Sindbis virus RNA vectors for heterologous gene expression
1998 StandoutNobel
Mechanisms of Endocytosis
2009 Standout
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
The Phosphoinositide 3-Kinase Pathway
2002 StandoutScience
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Short Hairpin RNA Interference Therapy for Ischemic Heart Disease
2008
Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
2004 StandoutScience
Works of Robert D. Simari being referenced
Clinical Trials in Vascular Gene Therapy
2002
Coronary artery apoptosis in experimental hypercholesterolemia
1999
Modulation of the vascular response to injury by autologous blood-derived outgrowth endothelial cells
2004
The Bile Acid Taurochenodeoxycholate Activates a Phosphatidylinositol 3-Kinase-dependent Survival Signaling Cascade
2000
Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries.
1996
Activated nuclear factor-κB is present in the coronary vasculature in experimental hypercholesterolemia
2000
Use of blood outgrowth endothelial cells as virus-producing vectors for gene delivery to tumors
2004
A New Cationic Liposome DNA Complex Enhances the Efficiency of Arterial Gene Transfer In Vivo
1996
Autologous Culture-Modified Mononuclear Cells Confer Vascular Protection After Arterial Injury
2003
Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury.
1996
Diverse Origin and Function of Cells With Endothelial Phenotype Obtained From Adult Human Blood
2003
Identification of a Monocyte-Predisposed Hierarchy of Hematopoietic Progenitor Cells in the Adventitia of Postnatal Murine Aorta
2011
Role for Tissue Factor Pathway in Murine Model of Vascular Remodeling
2001
Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces
2014
Selective Stimulation of Caveolar Endocytosis by Glycosphingolipids and Cholesterol
2004
Simvastatin Preserves Coronary Endothelial Function in Hypercholesterolemia in the Absence of Lipid Lowering
2001
Clinical Features, Management, and Prognosis of Spontaneous Coronary Artery Dissection
2012
Apoptosis
1999
Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks
2004
Caveolin-1 Can Regulate Vascular Smooth Muscle Cell Fate by Switching Platelet-Derived Growth Factor Signaling From a Proliferative to an Apoptotic Pathway
2003
Cell Surface Trafficking of Fas: A Rapid Mechanism of p53-Mediated Apoptosis
1998 Science
Gene Transfer Into Normal and Atherosclerotic Human Blood Vessels
1998
Defining Gene Transfer Before Expecting Gene Therapy
2002
Smoking Is Associated With Epicardial Coronary Endothelial Dysfunction and Elevated White Blood Cell Count in Patients With Chest Pain and Early Coronary Artery Disease
2007
Presence of Tissue Factor Pathway Inhibitor in Human Atherosclerotic Plaques Is Associated With Reduced Tissue Factor Activity
1998