Standout Papers
Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Bosentan Therapy in Patients With Eisenmenger Syndrome
2006
Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia.
2006
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism
2013 Standout
Role of endothelin-1 in lung disease
2001
Central and peripheral factors contributing to obstructive sleep apneas
2013
A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology
2007
Plasma levels of thrombomodulin in pulmonary hypertension
1996
Pulmonary hypertension: pathophysiology as a basis for clinical decision making
1999
Pulmonary hypertension in chronic obstructive pulmonary disease
2003
Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxaemic COPD patients
2001
Hypoxia inducible factor-1α in human emphysema lung tissue
2010
Mechanisms of Thrombus Formation
2008 Standout
Pulmonary rehabilitation in chronic respiratory insufficiency. 5. Home mechanical ventilation.
1993
Primary Pulmonary Hypertension
2000
Endothelin Peptides: Biological Activities, Cellular Signalling and Clinical Significance
1992
Endothelin-1 in primary pulmonary hypertension and the Eisenmenger syndrome
1993
Medical Therapy For Pulmonary Arterial Hypertension
2004
Regulation of endothelin-1 synthesis in human pulmonary arterial smooth muscle cells effects of transforming growth factor-β and hypoxia
2001
The Orally Active Nonpeptide Endothelin A-Receptor Antagonist A-127722 Prevents and Reverses Hypoxia-Induced Pulmonary Hypertension and Pulmonary Vascular Remodeling in Sprague-Dawley Rats
1997
Clinical Efficacy of Sitaxsentan, an Endothelin-A Receptor Antagonist, in Patients With Pulmonary Arterial Hypertension
2002
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Endothelin antagonism with bosentan: a review of potential applications
1999
Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension
2003
Treatment of Pulmonary Arterial Hypertension
2004 Standout
Rivaroxaban in Patients with a Recent Acute Coronary Syndrome
2011 Standout
CURRENT THOUGHTS REGARDING TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
1996
Elastase and the Pathobiology of Unexplained Pulmonary Hypertension
1998
Negative pressure ventilation in the treatment of acute respiratory failure: an old noninvasive technique reconsidered
1996
Nocturnal Positive-Pressure Ventilation via Nasal Mask in Patients with Severe Chronic Obstructive Pulmonary Disease
1991
Antithrombotic Therapy for VTE Disease
2016 Standout
5‐hydroxytryptamine and the pulmonary circulation: receptors, transporters and relevance to pulmonary arterial hypertension
2000
Rare diseases bullet 5: Primary pulmonary hypertension
1999
One-Year Outcomes in Survivors of the Acute Respiratory Distress Syndrome
2003 Standout
Cellular and molecular pathobiology of pulmonary arterial hypertension
2004 Standout
Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease
1995 Standout
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
1998 StandoutNobel
Central venous pressure: A useful but not so simple measurement
2006
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Ca2+/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
2004 StandoutNobel
Angiogenesis in cancer and other diseases
2000 StandoutNature
Primary Pulmonary Hypertension
1997 Standout
Pulmonary Arterial Hypertension
2006
Severe Sepsis and Septic Shock
2013 Standout
Acute Exacerbations in Severe COLD Patients
1992
Sarcoidosis of the Heart
1993
Primary pulmonary hypertension
2003
Long-Term Oxygen Therapy
1995
Dyspnea and Activity Limitation in COPD: Mechanical Factors
2007
Randomized Controlled Trial of Dietary Creatine as an Adjunct Therapy to Physical Training in Chronic Obstructive Pulmonary Disease
2008
An Imbalance between the Excretion of Thromboxane and Prostacyclin Metabolites in Pulmonary Hypertension
1992
Acute Renal Failure
1996 Standout
Reduced Expression of Endothelial Nitric Oxide Synthase in the Lungs of Patients with Pulmonary Hypertension
1995
Effects of Long-Term Bosentan in Children With Pulmonary Arterial Hypertension
2005
Antithrombotic Therapy for VTE Disease
2012 Standout
DANCE, a Novel Secreted RGD Protein Expressed in Developing, Atherosclerotic, and Balloon-injured Arteries
1999 StandoutNobel
Non-invasive modalities of positive pressure ventilation improve the outcome of acute exacerbations in COLD patients
1993
Endothelin-1 in the lungs of patients with pulmonary hypertension
1997
Clinical Exercise Testing
2001
The Emerging Concept of Vascular Remodeling
1994
Endothelin antagonists
1999
Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
2007
Mediators of Chronic Obstructive Pulmonary Disease
2004
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebocontrolled study
2001 Standout
Big Endothelin-1 and Endothelin-1 Plasma Levels Are Correlated With the Severity of Primary Pulmonary Hypertension
2001
Autophagy in Human Health and Disease
2013 Standout
Endothelin—Biology and disease
2010
Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines.
1997
Noninvasive Face Mask Mechanical Ventilation in Patients with Acute Hypercapnic Respiratory Failure
1991
Bosentan Therapy for Pulmonary Arterial Hypertension
2002 Standout
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
Nuclear Signaling by Endothelin-1 Requires Src Protein-tyrosine Kinases
1996
Autophagic Protein LC3B Confers Resistance against Hypoxia-induced Pulmonary Hypertension
2010
Ambrisentan Therapy for Pulmonary Arterial Hypertension
2005
Phosphorylation and Desensitization of Human Endothelin A and B Receptors
1997 StandoutNobel
Three-Dimensional Reconstruction of Pulmonary Arteries in Plexiform Pulmonary Hypertension Using Cell-Specific Markers
1999
Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation.
1997
Idiopathic Pulmonary Fibrosis
2001 Standout
Sarcoidosis
1997 Standout
Effects of written action plan adherence on COPD exacerbation recovery
2010
Chronic Lung Allograft Rejection: Mechanisms and Therapy
2009
Pulmonary Arterial Hypertension
2004
The new clinical trials on pharmacological treatment in pulmonary arterial hypertension
2002
Ambulatory oxygen improves quality of life of COPD patients: a randomised controlled study
2002
Endothelins
1995
Endothelin receptor subtypes and their role in transmembrane signaling mechanisms
1995
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Nasal Positive Pressure Ventilation in Patients with Acute Respiratory Failure
1991
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Noninvasive Ventilation: Does it Work, for Whom, and How?
1993
Mechanisms of disease: pulmonary arterial hypertension
2011
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia.
1993
Noninvasive Pressure Support Ventilation in Patients With Acute Respiratory Failure
1995
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Carbon Monoxide and Nitric Oxide Suppress the Hypoxic Induction of Vascular Endothelial Growth Factor Gene via the 5′ Enhancer
1998 StandoutNobel
Biomarkers in Heart Failure
2008 Standout
The human side of hypoxia‐inducible factor
2008 StandoutNobel
Chronic thromboembolic pulmonary hypertension
2014
Oral Apixaban for the Treatment of Acute Venous Thromboembolism
2013 Standout
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Introduction
2004
Rapid Measurement of B-Type Natriuretic Peptide in the Emergency Diagnosis of Heart Failure
2002 Standout
Pulmonary Vascular Involvement in COPD
2008
Sitaxsentan Therapy for Pulmonary Arterial Hypertension
2003
Prostacyclin Synthase Expression Is Decreased in Lungs from Patients with Severe Pulmonary Hypertension
1999
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Effects of Hyperoxia on Ventilatory Limitation During Exercise in Advanced Chronic Obstructive Pulmonary Disease
2001
Short-term Oral Administration of l- Arginine Improves Hemodynamics and Exercise Capacity in Patients with Precapillary Pulmonary Hypertension
2001
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism
2017 Standout
The Transcriptional Program in the Response of Human Fibroblasts to Serum
1999 StandoutScience
Activation of hypoxia-inducible factor-1 in pulmonary arterial smooth muscle cells by endothelin-1
2013 StandoutNobel
Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension
2004
Pulmonary Arterial Hypertension
2006
Functional Arteries Grown in Vitro
1999 StandoutScience
CLINICAL EXERCISE TESTING IN INTERSTITIAL LUNG DISEASE
1994
Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension
2006
Endothelin and Collagen Vascular Disease: A Review with Special Reference to Raynaud's Phenomenon and Systemic Sclerosis.
1994
Protective Role of Angiopoietin-1 in Experimental Pulmonary Hypertension
2003
Attenuation of Compensation of Endogenous Cardiac Natriuretic Peptide System in Chronic Heart Failure
1997
Warfarin plus Aspirin after Myocardial Infarction or the Acute Coronary Syndrome: Meta-Analysis with Estimates of Risk and Benefit
2005
Hemodynamic Effects of Bosentan, an Endothelin Receptor Antagonist, in Patients With Pulmonary Hypertension
2000
Pulmonary Vasoconstriction and Hypertension in Mice With Targeted Disruption of the Endothelial Nitric Oxide Synthase (NOS 3) Gene
1997
EndothelinB receptor‐mediated contraction in human pulmonary resistance arteries
1996
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism
2012 Standout
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension
2002
Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinaseThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.
2010
ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension
2009 Standout
Gene Expression Patterns in the Lungs of Patients With Primary Pulmonary Hypertension
2001
Voltage-Insensitive Ca2+Channels and Ca2+/Calmodulin-Dependent Protein Kinases Propagate Signals from Endothelin-1 Receptors to the c-fosPromoter
1996
Secondary Pulmonary Hypertension in Chronic Heart Failure
2000
Review of bosentan in the management of pulmonary arterial hypertension-0
2011
Works of Robert D. Levy being referenced
Maximal Exercise Testing for the Selection of Heart Transplantation Candidates
1999
Negative Pressure Ventilation
1989
Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?
1991
The Association Between Small Airway Obstruction and Emphysema Phenotypes in COPD
2007
Ventilatory Muscle Support in Respiratory Failure with Nasal Positive Pressure Ventilation
1990
A Canadian, Multicentre, Randomized Clinical Trial of Home‐Based Pulmonary Rehabilitation in Copd: Rationale and Methods
2005
Mechanisms of apnea termination in obstructive sleep apnea. Role of chemoreceptor and mechanoreceptor stimuli.
1994
Subclinical Cardiac Dysfunction in Sarcoidosis
1991
Bronchiolitis obliterans following lung transplantation: early detection using computed tomographic scanning
2006
Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
1993 Standout
Cardiac versus noncardiac limits to exercise after heart transplantation
1998
Exercise performance after lung transplantation.
1993
Induction of sleep apnoea with negative pressure ventilation in patients with chronic obstructive lung disease.
1992
Short-term Pulmonary Vasodilation Withl -Arginine in Pulmonary Hypertension
1995
Diagnostic Evaluation and Management of Chronic Thromboembolic Pulmonary Hypertension: A Clinical Practice Guideline
2010
Ventilatory muscle function during exercise in air and oxygen in patients with chronic air-flow limitation.
1985