Citation Impact
Citing Papers
Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis
2005 Standout
International Union of Pharmacology nomenclature of adrenoceptors.
1994 StandoutNobel
4-Alkylpiperidines related to SR-48968: Potent antagonists of the neurokinin-2 (NK2) receptor
1998
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
Structure–activity relationships of indole cytosolic phospholipase A 2 α inhibitors: substrate mimetics
2003
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Non-conventional hydrolase chemistry: amide and carbamate bond formation catalyzed by lipases
1999
ATP as a Cotransmittera
1990
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
Amide bond formation: beyond the myth of coupling reagents
2008 Standout
Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones
2000
Strategies for the inhibition of serine proteases
2001
Animal models of chronic obstructive pulmonary disease
2008
Synthetic Inhibitors of Elastase
1994
The pharmacogenetics of asthma: a candidate gene approach
2001
The intracellular oxidation of 2′,7′-dichlorofluorescin in murine T lymphocytes
2001
Nonredox 5-Lipoxygenase Inhibitors Require Glutathione Peroxidase for Efficient Inhibition of 5-Lipoxygenase Activity
1998
SAR studies of capsazepinoid bronchodilators 3: The thiourea part (coupling region) and the 2-(4-chlorophenyl)ethyl moiety (C-region)
2007
Characterization of a primate model of asthma using anti-allergy/ anti-asthma agents
1996
Role of the 5-HT receptor in neurogenic inflammation in Fisher 344 rat airways
1997
Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II)
1994
Peptidomimetics derived from natural products
1993
Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects
1991
Treatment of Asthma with Drugs Modifying the Leukotriene Pathway
1999
Carboxylic Acid (Bio)Isosteres in Drug Design
2013
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
2 Inhibitors of Human Leukocyte Elastase
1994
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy
1992
1,2,4-Oxadiazolidin-3,5-diones and 1,3,5-triazin-2,4,6-triones as cytosolic phospholipase A2α inhibitors
2006
N,N`-dissuccinimidyl carbonate: a useful reagent for alkoxycarbonylation of amines
1992
Di(2-pyridyl) carbonate promoted alkoxycarbonylation of amines: A convenient synthesis of functionalized carbamates
1991
Synthesis andin-vitroEvaluation of Novel Low Molecular Weight Thiocarbamates as Inhibitors of Human Leukocyte Elastase
2001
Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs
1999 Standout
5-Substituted-1H-tetrazoles as carboxylic acid isosteres: medicinal chemistry and synthetic methods
2002 Standout
Mechanism for slow-binding inhibition of human leukocyte elastase by valine-derived benzoxazinones
1987
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Specificity, stability, and potency of monocyclic .beta.-lactam inhibitors of human leukocyte elastase
1992
Mechanism of inhibition of human leukocyte elastase by monocyclic .beta.-lactams
1993
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response
2000 Standout
cPLA2 is phosphorylated and activated by MAP kinase
1993 Standout
Isolated Bronchi from Asthmatics Are Hyperresponsive to Adenosine, which Apparently Acts Indirectly by Liberation of Leukotrienes and Histamine
1992
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Proteinase 3, a Potent Secretagogue in Airways, Is Present in Cystic Fibrosis Sputum
1999
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Practical Route to a New Class of LTD4 Receptor Antagonists
1996
Contractile activities of several cysteine-containing leukotrienes in the guinea-pig lung strip
1982
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
A general method for C3 reductive alkylation of indoles
2003
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
Characterization of α‐adrenoceptors in the myocardium
1973
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Bis- and Trisindolylmethanes (BIMs and TIMs)
2009 Standout
Chemical Routes for the Transformation of Biomass into Chemicals
2007 Standout
Biological activity of WIN 63759, an orally bioavailable inhibitor of human neutrophil elastase
1995
From Styrenes to Enantiopure α-Arylglycines in Two Steps
1998 StandoutNobel
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
The effect of indomethacin on the contractile response of the guinea‐pig lung parenchymal strip to leukotrienes B4, C4, D4 and E4
1983 StandoutNobel
Organic Carbonates
1996 Standout
Carbon capture and conversion using metal–organic frameworks and MOF-based materials
2019 StandoutNobel
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Transformation of Carbon Dioxide
2007 Standout
Effects of Indomethacin on the Guinea-Pig Pulmonary Response to Intravenous Leukotrienes C4 and D4
1983 StandoutNobel
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Regulation of acetylcholine synthesis in nervous tissue
1977
Mechanism of inactivation of human leukocyte elastase by a chloromethyl ketone: kinetic and solvent isotope effect studies
1986
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
Inhibitors of human leukocyte elastase. 2.1 synthesis and sar of benzisothiazolinylmethyl aryl ethers
1995
Chirality in α- and β-adrenoceptor agonists and antagonists
1991
Organic Carbonates as Solvents in Synthesis and Catalysis
2010 Standout
Small-Molecule H-Bond Donors in Asymmetric Catalysis
2007 Standout
Protease Inhibitors: Current Status and Future Prospects
2000
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Nonpeptidic Inhibitors of Human Neutrophil Elastase. 7. Design, Synthesis, and in Vitro Activity of a Series of Pyridopyrimidine Trifluoromethyl Ketones
1996
Chemistry of Biologically Important Synthetic Organoselenium Compounds
2001 Standout
Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects
1987 StandoutScienceNobel
β-adrenoceptor studies. 6. Further investigations on the hybrid nature of the rat adipocyte β-adrenoceptor
1980
Alpha-adrenergic receptors in rat myocardium. Identification by binding of [3H]dihydroergocryptine.
1978 StandoutNobel
THYROID HORMONE‐DEPENDENT INTERCONVERSION OF MYOCARDIAL α‐ AND β‐ADRENOCEPTORS IN THE RAT
1977
The Cholinergic Hypothesis of Geriatric Memory Dysfunction
1982 StandoutScience
Molecular Characterization of the Human β 3 -Adrenergic Receptor
1989 StandoutScience
Emerging Targets in Photopharmacology
2016 StandoutNobel
Deracemizing α‐Branched Carboxylic Acids by Catalytic Asymmetric Protonation of Bis‐Silyl Ketene Acetals with Water or Methanol
2019 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.
1984 StandoutNobel
REGULATION AND INHIBITION OF PHOSPHOLIPASE A2
1999
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Is there a basis for distinguishing two types of P2-purinoceptor?
1985
A benzisothiazolone class of potent, selective mechanism-based inhibitors of human leukocyte elastase
1994
Asymmetric Synthesis of Functionalized 1,2,3,4-Tetrahydroquinolines
2001
Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
1987 StandoutScience
5‐Substituted 1H‐Tetrazoles as Carboxylic Acid Isosteres: Medicinal Chemistry and Synthetic Methods
2003 Standout
Proton-Coupled Electron Transfer
2012 Standout
Differentiation of β-adrenoceptors in right atrium, diaphragm and adipose tissue of the rat, using stereoisomers of propranolol, alprenolol, nifenalol and practolol
1977
Works of Robert D. Krell being referenced
STERIC ASPECTS OF ADRENERGIC DRUGS. XIX. INFLUENCE OF VARIOUS FACTORS ON THE STEREO-SELECTIVITY OF PRE- AND POSTJUNCTIONAL SITES TO NOREPINEPHRINE ISOMERS IN ISOLATED RAT VASA DEFERENTIA
1972
STERIC ASPECTS OF ADRENERGIC DRUGS. XX. ACCUMULATION OF (-)- AND (+)-NOREPINEPHRINE-14C BY PERIPHERAL TISSUES OF THE RAT
1972
COMBINATIONS OF ALPHA AND BETA ADRENERGIC BLOCKERS IN ISOLATED GUINEA-PIG ATRIA
1969
In vivo pharmacology of ICI 198,615: a novel, potent and selective peptide leukotriene antagonist.
1987
In vitro pharmacology of ICI 198,615: a novel, potent and selective peptide leukotriene antagonist.
1987
A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig.
1991
Biologic Characterization of ICI 200,880 and ICI 200,355, Novel Inhibitors of Human Neutrophil Elastase
1991
Inhibition of human neutrophil elastase by ICI 200,355
1991
The Preclinical Pharmacology of ICI 204,219: A Peptide Leukotriene Antagonist
1990
A novel series of selective leukotriene antagonists: exploration and optimization of the acidic region in 1,6-disubstituted indoles and indazoles
1990
Peptide leukotrienes: current status of research
1991
Evolution of a series of peptidoleukotriene antagonists: synthesis and structure-activity relationships of 1,6-disubstituted indoles and indazoles
1990
Biochemistry and Pharmacology of ICI 200,880, a Synthetic Peptide Inhibitor of Human Neutrophil Elastase
1991
Inhibition by REV-5901 of leukotriene release from guinea-pig and human lung tissue in vitro
1989
The 5-lipoxygenase inhibitors ZD2138 and ZM230487 are potent and selective inhibitors of several antigen-induced guinea-pig pulmonary responses
1994
Tachykinin-induced dyspnea in conscious guinea pigs
1992
Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles
1990
Pharmacological Studies of Tachykinin Receptors Mediating Contraction of Isolated Airway Smooth Muscle
1991
Imidodisulfamides. 2. Substituted 1,2,3,4-tetrahydroisoquinolinylsulfonic imides as antagonists of slow-reacting substance of anaphylaxis
1982
The effect of inhaled leukotriene D4 in humans.
1985
Effect of choline acetyltransferase inhibitors on mouse and guinea-pig brain choline and acetylcholine
1975
Pharmacological evidence that human intralobar airways do not contain different receptors that mediate contractions to leukotriene C4 and leukotriene D4.
1986
Summary: the enzymes, accessory proteins, and receptors of leukotriene metabolism and their inhibition and antagonism.
1994
Contraction of isolated airway smooth muscle by synthetic leukotrienes C4 and D4
1981
PHARMACOLOGICAL CHARACTERIZATION OF THE EXCITATORY INNERVATION TO THE GUINEA‐PIG URINARY BLADDER in vitro: EVIDENCE FOR BOTH CHOLINERGIC AND NON‐ADRENERGIC‐NON‐CHOLINERGIC NEUROTRANSMISSION
1981
Imidodisulfamides. 1. A novel class of antagonists of slow-reacting substance of anaphylaxis
1982
The effects of nucleotides on the response of the isolated guinea pig urinary bladder to nonadrenergic, noncholinergic nerve stimulation
1981
Steric aspects of adrenegic drugs. XV. Use of isomeric activity ratio as a criterion to differentiate adrenergic receptors.
1971
Purification of Human Leukocyte Elastase and Cathepsin G by Chromatography on Immobilized Elastin
1983
Biology of the Leukotrienes
1987
Airway hyperreactivity to pharmacologic agents in rhesus monkeys cutaneously hypersensitive to ascaris antigen
1976