Citation Impact
Citing Papers
Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV
2012
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes
2011
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β
2003
COMMD1 promotes the ubiquitination of NF‐κB subunits through a cullin‐containing ubiquitin ligase
2006
A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics
2011 Standout
Wilson's disease: Current status
1992
Copper(ii) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin
2010
A novel copper complex of salicylaldehyde pyrazole hydrazone induces apoptosis through up-regulating integrin β4 in H322 lung carcinoma cells
2010
Wilson disease and canine copper toxicosis
1998
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
CSF copper concentrations, blood-brain barrier function, and coeruloplasmin synthesis during the treatment of Wilson's disease
2000
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Increased Basal Ganglia Iron Levels in Huntington Disease
1999
Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants
2010 Standout
Advances in metal-induced oxidative stress and human disease
2011 Standout
Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
2002 Standout
The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells
2001
A Phase II Trial of Tetrathiomolybdate After Surgery for Malignant Mesothelioma: Final Results
2008
COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion
2010
The ceruloplasmin and hydrogen peroxide system induces α-synuclein aggregation in vitro
2002
Copper toxicity, oxidative stress, and antioxidant nutrients
2003 Standout
Coordination chemistry of copper proteins: How nature handles a toxic cargo for essential function
2011
Shared Principles in NF-κB Signaling
2008 Standout
Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
2005
The effect of dietary zinc - and polyphenols intake on DMBA-induced mammary tumorigenesis in rats
2012
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
2010
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
Mouse brains deficient in H‐ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress
2002
The neurobiology of zinc in health and disease
2005 Standout
Balancing Acts
2004 Standout
Copper in diseases and treatments, and copper‐based anticancer strategies
2009
Copper in disorders with neurological symptoms: Alzheimer’s, Menkes, and Wilson diseases
2001
Novel Metals and Metal Complexes as Platforms for Cancer Therapy
2010
Zinc takes the center stage: its paradoxical role in Alzheimer’s disease
2003
Dinuclear copper(II) complexes with valsartan. Synthesis, characterization and cytotoxicity
2011
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Brain iron pathways and their relevance to Parkinson's disease
2001
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
2004
The rationale for targeting the LOX family in cancer
2012
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Ceruloplasmin and what it might do
2007
A tense situation: forcing tumour progression
2009 Standout
Charting the travels of copper in eukaryotes from yeast to mammals
2012
Homocysteine potentiates copper‐ and amyloid beta peptide‐mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's‐type neurodegenerative pathways
2001
Copper deficiency as an anti-cancer strategy.
2004
Wilson's disease and other neurological copper disorders
2014
Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases
2004
Bioorganometallic chemistry—from teaching paradigms to medicinal applications
2008 Standout
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Fluorescent indicators based on BODIPY
2011 Standout
The Role of Iron and Copper in the Aetiology of Neurodegenerative Disorders
2002
Inhibition of Angiogenesis by Aβ Peptides
2004
Copper biochemistry and molecular biology
1996
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization
2007
XIAP: Cell death regulation meets copper homeostasis
2007
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Alzheimer's Disease
2010 Standout
Oxidation of Cytosolic Proteins and Expression of Creatine Kinase BB in Frontal Lobe in Different Neurodegenerative Disorders
1999
Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease
2004
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
Perspectives on Wilson's disease
1990
Redox metals and neu rodegenerative disease
1999
Anticopper therapy against cancer and diseases of inflammation and fibrosis
2005
Turning Tumor-Promoting Copper into an Anti-Cancer Weapon via High-Throughput Chemistry
2010
Copper, Ceruloplasmin, Superoxide Dismutase and Iron Parameters in Parkinson's Disease
1999
Methods for studying synaptosomal copper release
2003
Neurobiology of Zinc and Zinc-Containing Neurons
1989
Elevated copper and oxidative stress in cancer cells as a target for cancer treatment
2008
A Tri‐copper(II) Complex Displaying DNA‐Cleaving Properties and Antiproliferative Activity against Cancer Cells
2012
COPPER AND ANGIOGENESIS: UNRAVELLING A RELATIONSHIP KEY TO CANCER PROGRESSION
2008
The Effect of Tetrathiomolybdate on Cytokine Expression, Angiogenesis, and Tumor Growth in Squamous Cell Carcinoma of the Head and Neck
2005
Coordination abilities of the 1–16 and 1–28 fragments of β-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study
2003
Neurodegenerative diseases and oxidative stress
2004 Standout
Overexpression of Alzheimer's Disease Amyloid-β Opposes the Age-dependent Elevations of Brain Copper and Iron
2002
The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene
1993 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Non-Caeruloplasmin Copper and Ferroxidase Activity in Mammalian Serum. Ferroxidase Activity and Phenanthroline-Detectable Copper in Human Serum in Wilson's Disease
1989
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP)
2009
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
The molecular pathology of Alzheimer's disease
1991 Standout
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells
2003
In Vivo Evaluation of Brain Iron in Alzheimer Disease Using Magnetic Resonance Imaging
2000
Physiology and Pathophysiology of Carnosine
2013 Standout
Chemical and Biological Profiles of Novel Copper(II) Complexes Containing S-Donor Ligands for the Treatment of Cancer
2008
Copper Control as an Antiangiogenic Anticancer Therapy: Lessons from Treating Wilson's Disease
2001
Copper Active Sites in Biology
2014 Standout
Lanthanide Luminescence for Biomedical Analyses and Imaging
2010 Standout
The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy
2007
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
Cooperative capture synthesis: yet another playground for copper-free click chemistry
2016 StandoutNobel
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging
2004
Follicular Helper CD4 T Cells (TFH)
2011 Standout
Phase I Study of Copper-Binding Agent ATN-224 in Patients with Advanced Solid Tumors
2008
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures
1999
[1] Role of free radicals and catalytic metal ions in human disease: An overview
1990 Standout
Advances in Treatment of Wilson Disease
2017
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Novel Complex of Copper and a Salicylaldehyde Pyrazole Hydrazone Derivative Induces Apoptosis through Up-Regulating Integrin β4 in Vascular Endothelial Cells
2009
The extracellular matrix at a glance
2010 Standout
In Situ Imaging of Metals in Cells and Tissues
2009
Copper-Dependent Cytotoxicity of 8-Hydroxyquinoline Derivatives Correlates with Their Hydrophobicity and Does Not Require Caspase Activation
2012
A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling
2012
Luminescent Functional Metal–Organic Frameworks
2011 Standout
Clioquinol, a Therapeutic Agent for Alzheimer's Disease, Has Proteasome-Inhibitory, Androgen Receptor–Suppressing, Apoptosis-Inducing, and Antitumor Activities in Human Prostate Cancer Cells and Xenografts
2007
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Linkage of the Wilson disease gene to chromosome 13 in North-American pedigrees.
1988
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1
2006
Copper storage diseases: Menkes, Wilson's, and Cancer
2004
Copper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm
2009
Antitumour metal compounds: more than theme and variations
2007
IAPs, RINGs and ubiquitylation
2005
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Bioavailable copper modulates oxidative phosphorylation and growth of tumors
2013
Paradoxical roles for lysyl oxidases in cancer—A prospect
2007
Accumulation of C-terminally truncated tau protein associated with vulnerability of the perforant pathway in early stages of neurofibrillary pathology in Alzheimer's disease
2001
Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity
2006
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head and neck cancer
2007
Copper-related diseases: From chemistry to molecular pathology
2009
Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation)
2009
Chelators at the Cancer Coalface: Desferrioxamine to Triapine and Beyond
2006
Superoxide dismutase 1 (SOD1) is essential for H 2 O 2 -mediated oxidation and inactivation of phosphatases in growth factor signaling
2008
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Creatine and Creatinine Metabolism
2000 Standout
Polymorphic microsatellites and Wilson disease (WD).
1993
Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation
2020
Works of Robert D. Dick being referenced
Radiotherapy and Antiangiogenic TM in Lung Cancer
2002
Use of zinc acetate to treat copper toxicosis in dogs
1992
Treatment of Wilson's disease with zinc: XV long-term follow-up studies
1998
XIAP Is a Copper Binding Protein Deregulated in Wilson's Disease and Other Copper Toxicosis Disorders
2006
Inhibition of the Growth of Squamous Cell Carcinoma by Tetrathiomolybdate-Induced Copper Suppression in a Murine Model
2003
Treatment of Wilson's disease with zinc XVI: Treatment during the pediatric years
2001
A novel role for XIAP in copper homeostasis through regulation of MURR1
2003
Initial Therapy of Patients With Wilson's Disease With Tetrathiomolybdate
1991
Correction of cerebrospinal fluid copper in Menkes Kinky Hair disease
1991
Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders
1996
Treatment of Wilson's disease with zinc. XVIII. Initial treatment of the hepatic decompensation presentation with trientine and zinc
2003
The Role of Copper Suppression as an Antiangiogenic Strategy in Head and Neck Squamous Cell Carcinoma
2001
Effects of Tetrathiomolybdate in a Mouse Model of Retinal Neovascularization
2004
Treatment of Wilson’s Disease with Zinc XII: Dose Regimen Requirements
1993
Treatment of Wilson’s disease with zinc. XVII: Treatment during pregnancy
2000
Studies of cholecystokinin-stimulated biliary secretions reveal a high molecular weight copper-binding substance in normal subjects that is absent in patients with Wilson's disease.
1988
Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.
2002
Treatment of Wilson’s Disease with Zinc II. Validation of Oral 64Copper with Copper Balance
1986
Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents.
1993
Treatment of Wilson's disease with zinc: III. Prevention of reaccumulation of hepatic copper.
1987
Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study.
2000
Treatment of Wilson's disease with zinc. XIII: Therapy with zinc in presymptomatic patients from the time of diagnosis.
1994