Standout Papers

Optimization of Mammalian–Cell Bioreactors 1987 2026 2000 2013 26
  1. Optimization of Mammalian–Cell Bioreactors (1987)
    Michael W. Young, Robert C. Dean Nature Biotechnology

Citation Impact

Citing Papers

Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases
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Clinical Efficacy, Safety and Tolerability of Collagenase Clostridium Histolyticum for the Treatment of Peyronie Disease in 2 Large Double-Blind, Randomized, Placebo Controlled Phase 3 Studies
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Tissue plasminogen activator (t-PA) production by human fibroblasts using a bioreactor with t-PA adsorption column
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Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
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Inflammation and cancer
2002 StandoutNature
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
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Epithelial-Mesenchymal Transitions in Development and Disease
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Cancer Metastasis: Building a Framework
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Intravital imaging of cell movement in tumours
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The emerging role of lncRNAs in cancer
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Dissemination and growth of cancer cells in metastatic sites
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Interleukin-6 is antiproliferative to a mouse hybridoma cell line and promotive for its antibody productivity
1992
Organic Causes of Erectile Dysfunction in Men Under 40
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Peyronie's Disease
2007
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
2003 Standout
The development of androgen-independent prostate cancer
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Extracellular Matrix Degradation and Remodeling in Development and Disease
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Macrophage Diversity Enhances Tumor Progression and Metastasis
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Antibiotic prophylaxis for cesarean section
2002
State-of-the-art of the production of retroviral vectors
2004
Molecular requirements for epithelial–mesenchymal transition during tumor progression
2005 Standout
Molecular genetics of prostate cancer
2000
Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients
2004
Continuous production of tissue plasminogen activator (t-PA) by human embryonic lung diploid fibroblast, IMR-90 cells, using a ceramic bed reactor
1991
Water or antiseptic for periurethral cleaning before urinary catheterization: A randomized controlled trial
2001
Cell-growth control by monomeric antigen: the cell surface expression of lysozyme-specific Ig V-domains fused to truncated Epo receptor
2000 StandoutNobel
The hallmarks of cancer
2012 Standout
Prostate Cancer
2003 StandoutNobel
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
Microenvironmental regulation of metastasis
2008 Standout
Repertoire Enhancement with Adoptively Transferred Female Lymphocytes Controls the Growth of Pre-Implanted Murine Prostate Cancer
2012 StandoutNobel
DD3PCA3-based Molecular Urine Analysis for the Diagnosis of Prostate Cancer
2003
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Review: Biological relevance of disseminated tumor cells in cancer patients
2008
Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis
2006 Standout
Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes
2001
Matrix metalloproteinases and tumor metastasis
2006 Standout
epic3: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England
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PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer.
2000
Biomedical applications of soft robotics
2018 Standout
GEL ENTRAPMENT AND MICRO-ENCAPSULATION: METHODS, APPLICATIONS AND ENGINEERING PRINCIPLES
1996
Understanding earnings quality: A review of the proxies, their determinants and their consequences
2010 Standout
The Management of Peyronie’s Disease: Evidence-based 2010 Guidelines
2010
Clinical practice guidelines for antimicrobial prophylaxis in surgery
2013 Standout
Linking Long-Range Research To Strategic Planning
1983
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Design of an actively actuated prosthetic socket
2010
Firm Performance and Mechanisms to Control Agency Problems between Managers and Shareholders
1996 Standout
Executive incentives and the horizon problem
1991
A Review of the Earnings Management Literature and Its Implications for Standard Setting
1999 Standout
Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression.
2000
Non-Smad TGF-β signals
2005 Standout
Conditional Loss of Nkx3.1 in Adult Mice Induces Prostatic Intraepithelial Neoplasia
2002
Earnings management through real activities manipulation
2006 Standout
Supporting innovation and venture development in established companies
1985
Colloidosomes: Selectively Permeable Capsules Composed of Colloidal Particles
2002 StandoutScience
Sockets for Limb Prostheses: A Review of Existing Technologies and Open Challenges
2018
A critical step in metastasis: in vivo analysis of intravasation at the primary tumor.
2000
Capital markets research in accounting
2001 Standout
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis
2002
Laser sintering of polyamides and other polymers
2011 Standout
Diagnostic potential of prostate-specific antigen expressing epithelial cells in blood of prostate cancer patients.
2003
ANDROGEN RECEPTOR GENE AMPLIFICATION AT PRIMARY PROGRESSION PREDICTS RESPONSE TO COMBINED ANDROGEN BLOCKADE AS SECOND LINE THERAPY FOR ADVANCED PROSTATE CANCER
2000
Linking Competitive Strategies with Human Resource Management Practices
1987 Standout
Regular Nonsteroidal Anti-Inflammatory Drug Use and Erectile Dysfunction
2011
Hoxb13is required for normal differentiation and secretory function of the ventral prostate
2003 StandoutNobel
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
2011 Standout
Review of supercritical CO2 power cycle technology and current status of research and development
2015 Standout
The Relation Between Earnings Management Using Real Activities Manipulation and Future Performance: Evidence from Meeting Earnings Benchmarks*
2010 Standout
Accrual-based and real earnings management activities around seasoned equity offerings
2010 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer
2000
The causes of project failure
1990 Standout
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
2006 Standout
The Management of Peyronie's Disease: Evidence-based 2010 Guidelines
2011
The economic implications of corporate financial reporting
2005 Standout

Works of Robert C. Dean being referenced

Large‐Scale Culture of Hybridoma and Mammalian Cells in Fluidized Bed Bioreactors
1987
Post-operative urinary tract infection and wound infection in women undergoing Caesarean section: a comparison of two study periods in 1985 and 1987
1990
Treatment of Peyronie's disease with oral pentoxifylline
2006
Physiology of Penile Erection and Pathophysiology of Erectile Dysfunction
2005
Blinded evaluation of reverse transcriptase-polymerase chain reaction prostate-specific antigen peripheral blood assay for molecular staging of prostate cancer
1999
The Temporal Mismatch—Innovation's Pace vs Management's Time Horizon
1974
Optimization of Mammalian–Cell Bioreactors
1987 StandoutNobel
Design and Operating Strategies for Immobilized Living Cell Reactor Systems
1986
DETECTION OF CIRCULATING PROSTATE SPECIFIC ANTIGEN EXPRESSING PROSTATIC CELLS IN THE BONE MARROW OF RADICAL PROSTATECTOMY PATIENTS BY SENSITIVE REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION
1999
EXPRESSION PROFILE OF AN ANDROGEN REGULATED PROSTATE SPECIFIC HOMEOBOX GENE NKX3.1 IN PRIMARY PROSTATE CANCER
2000
Volume Management
2003
Losses in Vaneless Diffusers of Centrifugal Compressors and Pumps: Analysis, Experiment, and Design
1966
Rankless by CCL
2026