Citation Impact
Citing Papers
MYC regulates the antitumor immune response through CD47 and PD-L1
2016 Science
Tissue-specific p19 Arf regulation dictates the response to oncogenic K-ras
2010
Seeding and Propagation of Untransformed Mouse Mammary Cells in the Lung
2008 Science
Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch
2006
Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer
2008
The transcriptional repressor Snail promotes mammary tumor recurrence
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
The myc Oncogene: arvelouslomplex
2002
Targeted Expression of GLI1 in the Mammary Gland Disrupts Pregnancy-induced Maturation and Causes Lactation Failure
2007
MYC on the Path to Cancer
2012 Standout
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Pro-senescence therapy for cancer treatment
2011
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
p53 — a Jack of all trades but master of none
2009
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Imaging in the era of molecular oncology
2008 StandoutNature
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance
2010
c-Myc, Genome Instability, and Tumorigenesis: The Devil Is in the Details
2006
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
2010
Cellular Senescence in Cancer and Aging
2007 Standout
PI3K pathway alterations in cancer: variations on a theme
2008
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
2007
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
2007 StandoutNobel
Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival
2011
Metastatic Pancreatic Cancer Is Dependent on Oncogenic Kras in Mice
2012
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Angiogenesis: an organizing principle for drug discovery?
2007 Standout
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Autophagy: Renovation of Cells and Tissues
2011 Standout
Models, mechanisms and clinical evidence for cancer dormancy
2007
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
A microenvironmental model of carcinogenesis
2007
c-MYC: more than just a matter of life and death
2002
Myc Target Transcriptomes
2006
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Distinct Thresholds Govern Myc's Biological Output In Vivo
2008
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
2002
p21 in cancer: intricate networks and multiple activities
2009 Standout
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
2014 Nature
Conditional transgenic models define how MYC initiates and maintains tumorigenesis
2006
The c-Myc target gene network
2006
The mighty mouse: genetically engineered mouse models in cancer drug development
2006
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
The many faces of c-MYC
2003
The c‐myc Promoter: Still MysterY and Challenge
2007
Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression
2009
The essence of senescence: Figure 1.
2010 Standout
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
2010 Nature
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions
2016
Combined Inactivation of MYC and K-Ras Oncogenes Reverses Tumorigenesis in Lung Adenocarcinomas and Lymphomas
2008
Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence
2009
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
Cancer therapeutics: Targeting the dark side of Myc
2005
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
TGFβ in Cancer
2008 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Reflecting on 25 years with MYC
2008 Standout
Oncogene-induced senescence: the bright and dark side of the response
2010
Generation of a functional mammary gland from a single stem cell
2006 StandoutNature
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
Transcriptional regulation and transformation by Myc proteins
2005
The Myc oncoprotein as a therapeutic target for human cancer
2006
The Hallmarks of Aging
2013 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Mechanisms of Disease: oncogene addiction—a rationale for molecular targeting in cancer therapy
2006
Tumor reversion: Correction of malignant behavior by microenvironmental cues
2003
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Myc Recruits P-TEFb to Mediate the Final Step in the Transcriptional Activation of the cad Promoter
2002
Wnt signalling in stem cells and cancer
2005 StandoutNature
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Senescence in tumours: evidence from mice and humans
2009
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Cellular senescence: hot or what?
2009
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition
2009
Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain Tumorigenesis
2008
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells
2008
α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini
2007
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response
2008 Nobel
Endogenous expression of Hras G12V induces developmental defects and neoplasms with copy number imbalances of the oncogene
2009
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
2009 StandoutScience
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
2003
Persistent ERK/MAPK Activation Promotes Lactotrope Differentiation and Diminishes Tumorigenic Phenotype
2014
An Oncogene-Induced DNA Damage Model for Cancer Development
2008 Science
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus
2005
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras
2008
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Dual Role of Transforming Growth Factor β in Mammary Tumorigenesis and Metastatic Progression
2005
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53
2009
Works of Robert Boxer being referenced
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
2007
Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation
2004
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
2001
Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation
2006
A novel doxycycline‐inducible system for the transgenic analysis of mammary gland biology
2002
Isoform-Specific Ras Activation and Oncogene Dependence during MYC- and Wnt-Induced Mammary Tumorigenesis
2006