Citation Impact
Citing Papers
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation
2019
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
2012
The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.
1996
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
1993 StandoutNobel
Autophagy and other vacuolar protein degradation mechanisms
1992
ALS-Linked Mutations Enlarge TDP-43-Enriched Neuronal RNA Granules in the Dendritic Arbor
2014
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
1993 StandoutNatureNobel
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner
1998
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
2001
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration
2013
Transmembrane domain-dependent sorting of proteins to the ER and plasma membrane in yeast
1997
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles
1997 StandoutNobel
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
The C-Terminal TDP-43 Fragments Have a High Aggregation Propensity and Harm Neurons by a Dominant-Negative Mechanism
2010
SNAP-mediated protein–protein interactions essential for neurotransmitter release
1995 StandoutNatureNobel
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Sec6/8 Complex Is Recruited to Cell–Cell Contacts and Specifies Transport Vesicle Delivery to the Basal-Lateral Membrane in Epithelial Cells
1998
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
1994 StandoutNobel
Amyotrophic lateral sclerosis
2017
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
SNAREpins: Minimal Machinery for Membrane Fusion
1998 StandoutNobel
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
2003
Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion
2013
Does COPI Go Both Ways?
1997 StandoutNobel
Endocytosis in yeast: Evidence for the involvement of a small GTP-binding protein (Ypt7p)
1992
Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells
1994 Nature
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis
1999
Vam2/Vps41p and Vam6/Vps39p Are Components of a Protein Complex on the Vacuolar Membranes and Involved in the Vacuolar Assembly in the Yeast Saccharomyces cerevisiae
1997 StandoutNobel
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
Parkin and Parkinsonʼs disease
2001
Storage and release of neurotransmitters
1993
Membrane Fusion
2003 StandoutNobel
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
The Ways of Endocytosis
1989
Part I: Parkin-associated proteins and Parkinson's disease
2003
Biogenesis of the Vacuole in Saccharomyces cerevisiae
1992
The Cell Biology of Antigen Processing and Presentation
1991
Structural and functional diversity in the leucine-rich repeat family of proteins
1996
Origins of Cell Polarity
1996
Molecular misreading: a new type of transcript mutation expressed during aging
2000
Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis
1994
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport
1989 StandoutNatureNobel
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Annexin VI is required for budding of clathrin-coated pits
1992 StandoutNobel
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
2018
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Amyotrophic Lateral Sclerosis
2001 Standout
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast
1995 StandoutNobel
Parkin and CASK/LIN-2 Associate via a PDZ-mediated Interaction and Are Co-localized in Lipid Rafts and Postsynaptic Densities in Brain
2002
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
DSS4-1 is a dominant suppressor of sec4-8 that encodes a nucleotide exchange protein that aids Sec4p function
1993 Nature
The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
2003
Phase to Phase with TDP-43
2017
Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae.
1995
In vitro fusion of endosomes following receptor-mediated endocytosis.
1988
Exorcising the Exocyst Complex
2012
Sequestration From Immune CD4 + T Cells of Mycobacteria Growing in Human Macrophages
1993 StandoutScienceNobel
Stress granules as crucibles of ALS pathogenesis
2013
Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport.
1993
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
2003
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Functional rafts in cell membranes
1997 StandoutNature
Membrane fusion machinery: Insights from synaptic proteins
1993 StandoutNobel
Of Flies and Fishes
1994 StandoutScienceNobel
Postsynaptic Membrane Fusion and Long-Term Potentiation
1998 StandoutScienceNobel
Ordering the Final Events in Yeast Exocytosis
2000
Membrane trafficking in the presynaptic nerve terminal
1995
A view of acidic intracellular compartments.
1988
The Docking Stage of Yeast Vacuole Fusion Requires the Transfer of Proteins from a Cis-Snare Complex to a Rab/Ypt Protein
2000
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
2005
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
2001
Reversible Merger of Membranes at the Early Stage of Influenza Hemagglutinin-mediated Fusion
2000
Regulation of endocytic pH by the Na+,K+-ATPase in living cells.
1989
TRANSPORT VESICLE DOCKING: SNAREs and Associates
1996
Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts.
1996
Targeting vesicles to specific sites on the plasma membrane: the role of the sec6/8 complex
1999
Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP
2001 Science
n-Sec1: a neural-specific syntaxin-bindingprotein.
1994
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro
1993
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Sec2p Mediates Nucleotide Exchange on Sec4p and Is Involved in Polarized Delivery of Post-Golgi Vesicles
1997
Polarization of cell growth in yeast II. The role of the cortical actin cytoskeleton
2000
Geranylgeranylated Snares Are Dominant Inhibitors of Membrane Fusion
2000 StandoutNobel
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
1998 StandoutNobel
Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients
1998 Science
The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.
1992
Reconstitution of Endosomal Proteolysis in a Cell-free System
1989
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice
2014
Localization of a yeast early Golgi mannosyltransferase, Och1p, involves retrograde transport.
1996
Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
2000
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Role of Stress Granules and RNA-Binding Proteins in Neurodegeneration: A Mini-Review
2013
Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles.
1992 StandoutNobel
Prediction of Nucleating Sequences from Amyloidogenic Propensities of Tau-Related Peptides
2006
Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models
2018
Proteins with leucine-rich repeats
1995 Nobel
Early and Progressive Impairment of Spinal Blood Flow—Glucose Metabolism Coupling in Motor Neuron Degeneration of ALS Model Mice
2011
Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway.
1993
Works of Robert Bowser being referenced
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis
2007
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
2010
Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations
2011
The septin CDCrel-1 binds syntaxin and inhibits exocytosis
1999
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
1997
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients
2012
Kinetics of hydrolysis of endocytosed substrates by mammalian cultured cells: Early introduction of lysosomal enzymes into the endocytic pathway
1990
Transgenic Rat Model of Neurodegeneration Caused by Mutation in the TDP Gene
2010
SEC6 encodes an 85 kDa soluble protein required for exocytosis in yeast
1992
Absence of echovirus sequences in brain and spinal cord of amyotrophic lateral sclerosis patients
2001
The cycle of SEC4 function in vesicular transport.
1993
Sec15 protein, an essential component of the exocytotic apparatus, is associated with the plasma membrane and with a soluble 19.5S particle.
1991
DECREASED mRNA EXPRESSION OF TIGHT JUNCTION PROTEINS IN LUMBAR SPINAL CORDS OF PATIENTS WITH ALS
2009
Fetal Alz-50 Clone 1 Interacts with the Human Orthologue of the Kelch-like Ech-Associated Protein
2004
Kinetics and temperature dependence of exposure of endocytosed material to proteolytic enzymes and low pH: Evidence for a maturation model for the formation of lysosomes
1987
Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis.
1992
The role of Myo2, a yeast class V myosin, in vesicular transport.
1995