Standout Papers
Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose
2005 StandoutNobel
Lymphatic function is required prenatally for lung inflation at birth
2014
A highly sensitive viscosity probe based on ferrocene-BODIPY dyads
2010
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D
2016
Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence
2011
Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine·guanine base pairs
1987 StandoutNobel
Synthesis of Naturally Occurring Polyynes
2006
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
1994
Phospholipid signaling
1995
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
2010 Standout
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation
1996
Long wavelength red fluorescent dyes from 3,5-diiodo-BODIPYs
2010
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
Spontaneous phosphatidylcholine transfer by collision between vesicles at high lipid concentration
1989
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
Atherosclerosis: current pathogenesis and therapeutic options
2011 Standout
A conserved threonine prevents self-intoxication of enoyl-thioester reductases
2017
The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans
2003
The X-ray structure of Brassica napus β-keto acyl carrier protein reductase and its implications for substrate binding and catalysis
2000
Rational Design, Synthesis, and Spectroscopic and Photophysical Properties of a Visible‐Light‐Excitable, Ratiometric, Fluorescent Near‐Neutral pH Indicator Based on BODIPY
2011
Synthesis of Luminescent Ethynyl‐Extended Regioisomers of Borate Complexes Based on 2‐(2′‐Hydroxyphenyl)benzoxazole
2013
Bis-naphthobipyrrolylmethene derived BODIPY complex: an intense near-infrared fluorescent dye
2013
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Dihydronaphthalene‐Fused Boron–Dipyrromethene (BODIPY) Dyes: Insight into the Electronic and Conformational Tuning Modes of BODIPY Fluorophores
2010
Virus entry: molecular mechanisms and biomedical applications
2004
Fluorescent indicators based on BODIPY
2011 Standout
A General Synthetic Strategy for the Design of New BODIPY Fluorophores Based on Pyrroles with Polycondensed Aromatic and Metallocene Substituents
2011
Ceramide Activates the Stress-activated Protein Kinases
1995
Membrane lipids: where they are and how they behave
2008 Standout
Atherosclerosis — An Inflammatory Disease
1999 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Synthesis, Spectroscopy, Crystal Structure Determination, and Quantum Chemical Calculations of BODIPY Dyes with Increasing Conformational Restriction and Concomitant Red‐Shifted Visible Absorption and Fluorescence Spectra
2010
Evidence That Ceramide Selectively Inhibits Protein Kinase C-α Translocation and Modulates Bradykinin Activation of Phospholipase D
1995
Interaction of Ceramides, Sphingosine, and Sphingosine 1-Phosphate in Regulating DNA Synthesis and Phospholipase D Activity
1995
Proline-catalysed Mannich reactions of acetaldehyde
2008 StandoutNatureNobel
Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo
2015 StandoutNobel
Benzene-fused BODIPYs: synthesis and the impact of fusion mode
2012
Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites
2000
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Structural analysis of two glycosphingolipids from the lipopolysaccharide‐lacking bacterium Sphingomonas capsulata
2000
Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium
2011
Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent
2002
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Template-directed synthesis of a genetic polymer in a model protocell
2008 StandoutNatureNobel
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
1995
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
A Reduction in Intestinal Cell pH Due to Loss of the Caenorhabditis elegans Na+/H+ Exchanger NHX-2 Increases Life Span
2003
A direct organocatalytic entry to sphingoids: asymmetric synthesis of d-arabino- and l-ribo-phytosphingosine
2006
Generalized solvent scales as a tool for investigating solvent dependence of spectroscopic and kinetic parameters. Application to fluorescent BODIPY dyes
2010
Recent advances in Sonogashira reactions
2011 Standout
Sphingomyelin‐Derived Lipids Differentially Regulate the Extracellular Signal‐Regulated Kinase 2 (ERK‐2) and c‐Jun N‐Terminal Kinase (JNK) Signal Cascades in Airway Smooth Muscle
1996
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.
1994 Standout
Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase
1975
Dissociation of endogenous cellular ceramide from NF-kappa B activation.
1994
Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis.
1995
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Investigation of polylysine-dipalmitoylphosphatidylglycerol interactions in model membranes
1986
The State of Lipid Rafts: From Model Membranes to Cells
2003
A simple, rapid, and sensitive DNA assay procedure
1980 Standout
p53 and Ceramide as Collaborators in the Stress Response
2013
A Flexible Route to Mannose 6-Phosphonate Functionalized Derivatives
2002
Relation of protein subunit interactions to the molecular species observed during cooperative binding of ligands.
1967
Amino-acid Sequence of Glyceraldehyde 3-Phosphate Dehydrogenase from Lobster Muscle
1967 Nature
X‐Ray Small‐Angle Scattering of Yeast Glyceraldehyde‐3‐phosphate Dehydrogenase as a Function of Saturation with Nicotinamide‐Adenine‐Dinucleotide
1971
Structural modification strategies for the rational design of red/NIR region BODIPYs
2014 Standout
The Absence of "Heme-Heme" Interactions in Hemoglobin
1969 StandoutScienceNobel
Oxidative Nucleobase Modifications Leading to Strand Scission
1998 Standout
Anthracene-Fused BODIPYs as Near-Infrared Dyes with High Photostability
2011
Total Synthesis of (+)-Zaragozic Acid C
2000
Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques: a study of neurally evoked postsynaptic currents and of voltage-jump relaxations.
1977
THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS
2005
Sequence and structure of D-glyceraldehyde 3-phosphate dehydrogenase from Bacillus stearothermophilus
1977 StandoutNatureNobel
Boron Reagents in Process Chemistry: Excellent Tools for Selective Reductions
2006
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides
1997 StandoutScience
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
Fluorescent indicators for cytosolic sodium
1989 StandoutNobel
Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells.
1993
Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts.
1994
Enantioselective synthesis of (S)-dapoxetine
2007
Kinetics of Folding of Staphylococcal Nuclease
1970 StandoutScienceNobel
Copper in cross-coupling reactions
2004 Standout
An improved synthesis of aziridine-2,3-dicarboxylates via azido alcohols—epimerization studies
2003
Change in synaptic channel gating during neuromuscular development
1978 StandoutNatureNobel
Chemoselective Elaboration of O-Linked Glycopeptide Mimetics by Alkylation of 3-ThioGalNAc
2001 StandoutNobel
Synthesis and Functionalization of Asymmetrical Benzo-Fused BODIPY Dyes
2010
3,5-Dianilino Substituted Difluoroboron Dipyrromethene: Synthesis, Spectroscopy, Photophysics, Crystal Structure, Electrochemistry, and Quantum-Chemical Calculations
2009
Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent
2002
Ceramide Inhibits Antigen Uptake and Presentation by Dendritic Cells
1996
Kinetics of Reversible Denaturation of Trypsin in Water and Water–Ethanol Mixtures
1968
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
Specificity of induced conformational changes. Case of yeast glyceraldehyde-3-phosphate dehydrogenase
1975
STUDIES OF ASYMMETRY IN THE THREE-DIMENSIONAL STRUCTURE OF LOBSTER D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
1975
General Route to Symmetric and Asymmetricmeso-CF3-3(5)-Aryl(hetaryl)- and 3,5-Diaryl(dihetaryl)-BODIPY Dyes
2011
A Concise and Scalable Synthesis of High Enantiopurity (−)-d -erythro-Sphingosine Using Peptidyl Thiol Ester−Boronic Acid Cross-Coupling
2007
The Emergence of Competition Between Model Protocells
2004 StandoutScienceNobel
Prelesional events in atherogenesis. Accumulation of extracellular cholesterol-rich liposomes in the arterial intima and cardiac valves of the hyperlipidemic rabbit.
1986
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Synthesis of BF2 Complexes of Prodigiosin Type Oligopyrroles
2011
Sonogashira Couplings of Halo‐ and Epoxy‐Halo‐exo‐Glycals: Concise Entry to Carbohydrate‐Derived Enynes
2010
Glyceraldehyde 3-phosphate dehydrogenases
1965
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Renaturation and tumor necrosis factor-alpha stimulation of a 97-kDa ceramide-activated protein kinase.
1994
Asymmetric synthesis of l-DOPA and (R)-selegiline via, OsO4-catalyzed asymmetric dihydroxylation
2004
The sphingomyelin cycle and the second messenger function of ceramide.
1994
Organ-specific lymphatic vasculature: From development to pathophysiology
2017
Asymmetric Enamine Catalysis
2007 StandoutNobel
Aminoborohydrides. 8. A facile reduction of aliphatic and benzylic azides to the corresponding amines in high yield and purity using lithium N,N-dimethylaminoborohydride
1995
A quantitative description of end‐plate currents
1972
Inhibition of the processing of ribosomal precursor RNA by intercalating agents
1971 StandoutNobel
Base pairing structure in the poly d(G-T) double helix: wobble base pairs
1978
Recent Advances in the Baylis−Hillman Reaction and Applications
2003 Standout
Perylene-Fused BODIPY Dye with Near-IR Absorption/Emission and High Photostability
2011
Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist
1980 StandoutNatureNobel
Prospects for the Future
2002 StandoutScienceNobel
Lymphatic System in Cardiovascular Medicine
2016
Boron dipyrromethene (BODIPY)-based photosensitizers for photodynamic therapy
2012
Works of Robert Bittman being referenced
Comparison of the capacity of β-cyclodextrin derivatives and cyclophanes to shuttle cholesterol between cells and serum lipoproteins
1999
Adaptation of Alphaviruses to Heparan Sulfate: Interaction of Sindbis and Semliki Forest Viruses with Liposomes Containing Lipid-Conjugated Heparin
2002
Sterol effects and sites of sterol accumulation in Caenorhabditis elegans
2003
Use of Bodipy-labeled sphingolipid and cholesterol analogs to examine membrane microdomains in cells
2008
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice
2013 Standout
Effect of ceramide N-acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts)
2007
Caveolar Endocytosis and Microdomain Association of a Glycosphingolipid Analog Is Dependent on Its Sphingosine Stereochemistry
2006
Correlated Fluorescence-Atomic Force Microscopy of Membrane Domains: Structure of Fluorescence Probes Determines Lipid Localization
2005
Rates of spontaneous exchange of synthetic radiolabeled sterols between lipid vesicles
1992
The Immunomodulator FTY720 Has a Direct Cytoprotective Effect in Oligodendrocyte Progenitors
2007
Ceramide channels: Influence of molecular structure on channel formation in membranes
2012
Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis
1995
Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase
2002
Sphingolipid and Cholesterol Dependence of Alphavirus Membrane Fusion
2002
Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate
1999
Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate
2011
BODIPY‐Cholesterol: A New Tool to Visualize Sterol Trafficking in Living Cells and Organisms
2008
Movement of cholesterol between vesicles prepared with different phospholipids or sizes.
1985
Stopped-flow kinetic studies of actinomycin binding to DNAs
1975
A simple synthesis of phosphonate - containing lipids. Introduction of the phosphonic acid moiety into hydrolytically-labile compounds
1975
First Synthesis of Free Cholesterol−BODIPY Conjugates
2006
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions
1999
An efficient synthesis of d-ribo- and l-lyxo-phytosphingosine from d-tartaric acid
2005
Studies of the binding of ethidium bromide to transfer ribonucleic acid: Absorption, fluorescence, ultracentrifugation and kinetic investigations
1969
Efficient synthesis of chiral α,β-epoxyesters via a cyclic sulfate intermediate
1998
Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed.
1993
Total Synthesis of Two Photoactivatable Analogues of the Growth-Factor-Like Mediator Sphingosine 1-Phosphate: Differential Interaction with Protein Targets
2003
Enantioselective Syntheses of 1-O-Benzyl-sn-glycerol and 1-O-Hexadecyl-2-O-methyl-sn-glycerol via Asymmetric Dihydroxylation of Allyl 4-Methoxyphenyl Ether. Use of AD-Mix Supplemented with Potassium Persulfate
1994
THE BINDING OF NICOTINAMIDE-ADENINE DINUCLEOTIDE TO YEAST D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE: TEMPERATURE-JUMP RELAXATION STUDIES ON THE MECHANISM OF AN ALLOSTERIC ENZYME
1966
Effects of sterol structure and exogenous lipids on the transbilayer distribution of sterols in the membrane of Mycoplasma capricolum
1981
Vibrational assignment of the sn‐1 and sn‐2 chain carbonyl stretching modes of membrane phospholipids
1982
Permeability behavior of liposomes prepared from fatty acids and fatty acid methyl esters
1986
Bax and Bcl-xL exert their regulation on different sites of the ceramide channel
2012
Cyclic Sulfites and Cyclic Sulfates in Organic Synthesis
2000
Synthesis of C-Glycoside Analogues of α-Galactosylceramide via Linear Allylic C–H Oxidation and Allyl Cyanate to Isocyanate Rearrangement
2012
Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells
1994
Synthesis and Spectral Properties of Cholesterol- and FTY720-Containing Boron Dipyrromethene Dyes
2007
Fluorescence Studies of the Binding of the Polyene Antibiotics Filipin III, Amphotericin B, Nystatin, and Lagosin to Cholesterol
1972
Constraint of the spontaneous intermembrane movement of sitosterol by its 24.alpha.-ethyl group
1990
Binding properties of neutral diamide ligands for alkaline-earth cations
1977
Ceramide is a competitive inhibitor of diacylglycerol kinase in vitro and in intact human leukemia (HL-60) cells.
1992
Synthesis of Immunostimulatory α-C-Galactosylceramide Glycolipids via Sonogashira Coupling, Asymmetric Epoxidation, and Trichloroacetimidate-Mediated Epoxide Opening
2010
Synthesis of l -lyxo-Phytosphingosine and Its 1-Phosphonate Analogue Using a Threitol Acetal Synthon
2004
Convergent C-Glycolipid Synthesis via the Ramberg−Bäcklund Reaction: Active Antiproliferative Glycolipids
1999
Sphingolipid-dependent fusion of Semliki Forest virus with cholesterol-containing liposomes requires both the 3-hydroxyl group and the double bond of the sphingolipid backbone
1995
Inhibition of caveolar uptake, SV40 infection, and β1-integrin signaling by a nonnatural glycosphingolipid stereoisomer
2007
Synthesis of photopolymerizable long-chain conjugated diacetylenic acids and alcohols from butadiyne synthons
1991
Stereoselective Preparation of Ceramide and Its Skeleton Backbone Modified Analogues via Cyclic Thionocarbonate Intermediates Derived by Catalytic Asymmetric Dihydroxylation of α,β-Unsaturated Ester Precursors
2000
Antitumor ether lipids: An improved synthesis of ilmofosine and an enantioselective synthesis of an ilmofosine analog
1994