Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness
1979 StandoutNobel
Identification of the haematopoietic stem cell niche and control of the niche size
2003 StandoutNature
Regulatory T Cells Dynamically Control the Primary Immune Response to Foreign Antigen
2007
The Major Locus for Mouse Adenovirus Susceptibility Maps to Genes of the Hematopoietic Cell Surface-Expressed LY6 Family
2010
The Role of Ly49A and 5E6(Ly49C) Molecules in Hybrid Resistance Mediated by Murine Natural Killer Cells Against Normal T Cell Blasts
1996
Cytokines in inflammatory bowel disease
2014 Standout
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
1987 StandoutNature
Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
1993
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Function of PU.1 (Spi-1), C/EBP, and AML1 in Early Myelopoiesis: Regulation of Multiple Myeloid CSF Receptor Promoters
1996
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
Amyloid beta peptides and glutamatergic synaptic dysregulation
2007
MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade
2016
GABP and PU.1 Compete for Binding, yet Cooperate to Increase CD18 (β2 Leukocyte Integrin) Transcription
1995
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
The carbonic anhydrase domain of receptor tyrosine phosphatase β is a functional ligand for the axonal cell recognition molecule contactin
1995
Osteopetrosis in mice lacking haematopoietic transcription factor PU.1
1997 Nature
A Low Interleukin-2 Receptor Signaling Threshold Supports the Development and Homeostasis of T Regulatory Cells
2009
Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions
1997
Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
2009
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
Protein modules and signalling networks
1995 StandoutNature
Regulation of NMDA receptor trafficking by amyloid-β
2005
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Genetic, Biochemical, and Clinical Features of Chronic Granulomatous Disease
2000
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
2007
Self-tolerance of natural killer cells
2006
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Points of control in inflammation
2002 StandoutNature
Tolerance, not immunity, crucially depends on IL-2
2004
The binding site for C1q on IgG
1988 StandoutNatureNobel
Toward Regenerative Medicine
2001
Granzyme B and Perforin Are Important for Regulatory T Cell-Mediated Suppression of Tumor Clearance
2007
acr-16 Encodes an Essential Subunit of the Levamisole-resistant Nicotinic Receptor at the Caenorhabditis elegans Neuromuscular Junction
2005
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
2011
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
2006 Nature
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning
2002
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Total Body Irradiation and Acute Graft-Versus-Host Disease: The Role of Gastrointestinal Damage and Inflammatory Cytokines
1997
Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1.
1993
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Unrestricted killer cells recognize an antigen controlled by a gene linked toTla
1979
Acidic “peptidophospholipids”, a new class of hapten-bearing cell surface modifying reagents
1984
Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping
1989 StandoutScience
The human beta 2 integrin CD18 promoter consists of two inverted Ets cis elements.
1994
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum
1983 StandoutNobel
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Effector and Memory CTL Differentiation
2006
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis
2006 Standout
Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
1989 StandoutNobel
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8+ T Cells to Cause Immunopathology
1998
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
Bone Resorption by Osteoclasts
2000 StandoutScience
Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens
1982 Nature
Biology of Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application
2003
Donor-type CD4+CD25+ Regulatory T Cells Suppress Lethal Acute Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation
2002
Characterization of the myeloid-specific CD11b promoter
1992
Cell Membrane Antigens Recognized by Anti‐Viral and Anti‐Trinitrophenyl Cytotoxic T Lymphocytes
1981
Inactivation of Smad-Transforming Growth Factor β Signaling by Ca2+-Calmodulin-Dependent Protein Kinase II
2000
The beta 1 domain of the mouse E beta chain is important for restricted antigen presentation to helper T-cell hybridomas.
1985 StandoutNobel
Expression of a Microinjected Porcine Class I Major Histocompatibility Complex Gene in Transgenic Mice
1985 StandoutScienceNobel
The Biology of Interleukin-2
2007
Clusters of genes encoding mouse transplantation antigens
1982
A simple model for the immune network.
1990 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Allospecific and virus-specific cytolytic T lymphocytes are restricted to the N or C1 domain of H-2 antigens expressed on L cells after DNA-mediated gene transfer.
1983
Specific recognition of the product of a transferred major histocompatibility complex gene by cytotoxic T lymphocytes.
1982
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of β2integrin gene expression
2004
Structural analysis of an HLA-B27 functional variant: identification of residues that contribute to the specificity of recognition by cytolytic T lymphocytes.
1985
Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
1997 Standout
Functional and inducible expression of a transfected murine class II major histocompatibility complex gene.
1984 StandoutNobel
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.
1993
Neutrophil Extracellular Traps Kill Bacteria
2004 StandoutScience
Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants
2002 StandoutScience
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Naive CD8+ T cells differentiate into protective memory-like cells after IL-2–anti–IL-2 complex treatment in vivo
2007
The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).
1993
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Recognition of Self and Regulation of Specificity at the Level of Cell Populations
1984
Major Histocompatibility Complex Restricted Cell-Mediated Immunity
1978
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
PU.1 (Spi-1) and C/EBPα Regulate Expression of the Granulocyte-Macrophage Colony-Stimulating Factor Receptor α Gene
1995
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease
2004
The Molecular Biology of Axon Guidance
1996 StandoutScience
Association between transplantation antigens and a viral membrane protein synthesized from a mammalian expression vector
1983 StandoutNobel
Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion
2006
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells.
1978 StandoutNobel
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
Works of Robert B. Levy being referenced
Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma.
1991
Regulation and selective expression of Ly-6A/E, a lymphocyte activation molecule, in the central nervous system
1990
Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation
2010
Pathophysiologic mechanisms of acute graft-vs.-host disease
1999
The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice.
1996
Functional studies of the products of theH-2L locus
1980
Perforin- and Fas-mediated cytotoxic pathways are not required for allogeneic resistance to bone marrow grafts in mice.
1995
α7 Nicotinic Acetylcholine Receptors Occur at Postsynaptic Densities of AMPA Receptor-Positive and -Negative Excitatory Synapses in Rat Sensory Cortex
2002
Involvement of H-2L gene products in virus-immune T-cell recognition. Evidence for an H-2L-restricted T-cell response.
1978 StandoutNobel
Efficient Induction of Primary and Secondary T Cell-Dependent Immune Responses In Vivo in the Absence of Functional IL-2 and IL-15 Receptors
2003
Role of self and foreign antigenic determinants in allogeneic and self-restricted cytotoxic T cell recognition.
1980
Cloning and analysis of the CD18 promoter
1992
CD18 (beta 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity.
1995
Cell-mediated lympholysis responses against autologous cells modified with haptenic sulfhydryl reagents. IV. Self-determinants recognized by wild-type anti-H-2Kb and H-2Db-restricted cytotoxic T cells specific for sulfhydryl and amino-reactive haptens are absent in certain H-2 mutant strains.
1982
Correlation of suppressor cell development in parental and F1 hybrid mouse strains with the growth of a parental tumor in vivo.
1976
Cloning and analysis of the CD18 promoter
1992
Cutting Edge: Allogeneic CD4+CD25+Foxp3+ T Regulatory Cells Suppress Autoimmunity while Establishing Transplantation Tolerance
2006
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+regulatory T cells
2006
Alloantigens Determined by A Second D Region Locus Elicit A Strong In Vitro Cytotoxic Response
1978
CROSS-REACTIVITY AMONG THE PRODUCTS OF THREE NONALLELIC H-2 LOCI, H-2Ld, H-2Dq, AND H-2Kk
1979
MEK inhibitors selectively suppress alloreactivity and graft-versus-host disease in a memory stage-dependent manner
2013
Xenogeneic serum-induced murine cytotoxic cells
1979
AMPA receptor downscaling at the onset of Alzheimer’s disease pathology in double knockin mice
2006
Can cytotoxic T cells recognize self determinants on molecules lacking polymorphic MHC self determinants
1982
Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation
2004