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Selective deletion of leptin receptor in neurons leads to obesity
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Leptin Levels in Children with Central Precocious Puberty1
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Co-Localization of Growth Hormone Secretagogue Receptor and NPY mRNA in the Arcuate Nucleus of the Rat
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Ghrelin: An orexigenic and somatotrophic signal from the stomach
2001
Physiological Perspectives on Leptin as a Regulator of Reproduction: Role in Timing Puberty1
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Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains
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The Melanocortin 4 Receptor Mediates Leptin Stimulation of Luteinizing Hormone and Prolactin Surges in Steroid-Primed Ovariectomized Rats
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Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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Genetic mapping and analysis of somatostatin expression in Snell dwarf mice
1988
Down regulation of the prepro-orexin gene expression in genetically obese mice
1999
The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin
2000
Accelerated puberty and late-onset hypothalamic hypogonadism in female transgenic skinny mice overexpressing leptin
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The Need to Feed
2002
Ghrelin induces adiposity in rodents
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Effects of Pituitary Adenylate Cyclase‐Activating Polypeptide (PACAP) and Vasoactive Intestinal Polypeptide (VIP) on Prolactin, Luteinizing Hormone and Growth Hormone Secretion in the Ewe
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Functional interactions between the gut microbiota and host metabolism
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Leptin<sub>116–130</sub> Stimulates Prolactin and Luteinizing Hormone Secretion in Fasted Adult Male Rats
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Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
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Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
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Leptin Receptor Signaling in POMC Neurons Is Required for Normal Body Weight Homeostasis
2004
Leptin accelerates the onset of puberty in normal female mice.
1997
A Significant Role of Leptin in the Generation of Steroid-Induced Luteinizing Hormone and Prolactin Surges in Female Rats
1999
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Central Administration of Antiserum to Vasoactive Intestinal Peptide Delays and Reduces Luteinizing Hormone and Prolactin Surges in Ovariectomized, Estrogen-Treated Rats
1999
Psychobiological Mechanisms of Resilience and Vulnerability: Implications for Successful Adaptation to Extreme Stress
2004
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
2002
Cysteamine-Induced Enhancement of Growth Hormone- Releasing Factor (GRF) Immunoreactivity in Arcuate Neurons: Morphological Evidence for Putative Somatostatin/GRF Interactions within Hypothalamus*
1990
Obesity as a medical problem
2000 StandoutNature
Mice lacking melanin-concentrating hormone are hypophagic and lean
1998 Nature
The biology of leptin: a review.
1998
The stomach is a source of leptin
1998 Nature
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1998 StandoutNature
From Lesions to Leptin
1999
Somatostatin: the neuroendocrine story
1997
Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system
1998
Activation of Arcuate Nucleus Neurons by Systemic Administration of Leptin and Growth Hormone-Releasing Peptide-6 in Normal and Fasted Rats
1999
The Drosophila takeout Gene Is a Novel Molecular Link between Circadian Rhythms and Feeding Behavior
2000 StandoutNobel
Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain
1989
Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose‐responsive neurons to regulate Ca2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus
2004
Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight
1999
Leptin and reproduction
1999
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
2004
Long-Term Prospective and Controlled Studies Demonstrate Adipose Tissue Hypercellularity and Relative Leptin Deficiency in the Postobese State
2005
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Centrally Administered Murine Leptin Stimulates Plasma Arginine-Vasopressin Secretion and Increases the Level of mRNA Expression in the Supraoptic Nucleus of Conscious Rats
1999
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
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High-sensitive liquid chromatographic method for determination of neuronal release of serotonin, noradrenaline and dopamine monitored by microdialysis in the rat prefrontal cortex
2004
Prolactin Receptor mRNA Localization in the Hypothalamus by in situ Hybridization
1994
Unraveling the central nervous system pathways underlying responses to leptin
1998
Sleep Loss Reduces Diurnal Rhythm Amplitude of Leptin in Healthy Men
2003
Hypothalamic serotonin in control of eating behavior, meal size, and body weight
1998
Role of leptin in the neuroendocrine response to fasting
1996 StandoutNature
The molecular neurobiology of depression
2008 StandoutNature
Decreased plasma orexin-A levels in obese individuals
2002
Integration of NPY, AGRP, and Melanocortin Signals in the Hypothalamic Paraventricular Nucleus
1999
Body weight is regulated by the brain: a link between feeding and emotion
2005
Obesity and the Hypothalamus: Novel Peptides for New Pathways
1998
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
1995
Environmental factors and puberty in non‐human primates
1996
Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency
1999
Genetics of body-weight regulation
2000 Nature
The Geometry of Leptin Action in the Brain: More Complicated Than a Simple ARC
2009
Leptin Activates Hypothalamic CART Neurons Projecting to the Spinal Cord
1998
Leptin participates in the regulation of glucocorticoid and growth hormone axes
1998
Reversal of fasting-induced suppression of luteinizing hormone (LH) secretion in male rhesus monkeys by intragastric nutrient infusion: evidence for rapid stimulation of LH by nutritional signals.
1993
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*
1999
Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin
1998
A Biphasic Developmental Pattern of Circulating Leptin in the Male Rhesus Macaque (Macaca mulatta)*
1998
Evidence That the Caudal Brainstem Is a Target for the Inhibitory Effect of Leptin on Food Intake
2002
Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss
2010
Anatomy of an Endogenous Antagonist: Relationship between Agouti-Related Protein and Proopiomelanocortin in Brain
1999
Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance
1998
Distributions of leptin receptor mRNA isoforms in the rat brain
1998
Signals That Regulate Food Intake and Energy Homeostasis
1998 Science
Mode of action of OB protein (leptin) on feeding
1998
MtTW-10 pituitary tumor cells: galanin gene expression and peptide secretion.
1993
Authentic Cell-Specific and Developmentally Regulated Expression of Pro-Opiomelanocortin Genomic Fragments in Hypothalamic and Hindbrain Neurons of Transgenic Mice
1998
The Central Melanocortin System and Energy Homeostasis
1999
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
Region-Specific Leptin Resistance within the Hypothalamus of Diet-Induced Obese Mice
2004
Physiological and Anatomical Circuitry between Agouti-Related Protein and Leptin Signaling*
1999
Leptin Signaling in the Central Nervous System and the Periphery
2004
Induction of c-fos Messenger Ribonucleic Acid in Neuropeptide Y and Growth Hormone (GH)-Releasing Factor Neurons in the Rat Arcuate Nucleus Following Systemic Injection of the GH Secretagogue, GH-Releasing Peptide-6*
1997
Effects of preoptic injections of gastrin, cholecystokinin, secretin, vasoactive intestinal peptide and PHI on the secretion of luteinizing hormone and prolactin in ovariectomized estrogen-primed rats
1987
Leptin Increases Hypothalamic Pro-opiomelanocortin mRNA Expression in the Rostral Arcuate Nucleus
1997
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
1985 Standout
Excitatory Amino Acids: Evidence for a Role in the Control of Reproduction and Anterior Pituitary Hormone Secretion*
1997
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei
1998
Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men.
1996
Is the Energy Homeostasis System Inherently Biased Toward Weight Gain?
2003
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Low plasma leptin levels contribute to diabetic hyperphagia in rats.
1999
Fluorescent Sensors for Zn2+Based on a Fluorescein Platform: Synthesis, Properties and Intracellular Distribution
2001 StandoutNobel
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat.
1993
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
1998
Puberty in monkeys is triggered by chemical stimulation of the hypothalamus.
1989
Attenuation of the Obesity Syndrome of ob/ob Mice by the Loss of Neuropeptide Y
1996 Science
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase.
1995 StandoutNobel
Leptin Receptor‐ and STAT3‐Immunoreactivities in Hypocretin/Orexin Neurones of the Lateral Hypothalamus1
1999
Role of the CNS Melanocortin System in the Response to Overfeeding
1999
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Control of pulsatile insulin secretion in man
1983
Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
1998
Integration of Porous Coordination Polymers and Gold Nanorods into Core–Shell Mesoscopic Composites toward Light-Induced Molecular Release
2013 StandoutNobel
The G protein-coupled receptor repertoires of human and mouse
2003
Polycythemia in transgenic mice expressing the human erythropoietin gene.
1989 StandoutNobel
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Peptidomimetic Regulation of Growth Hormone Secretion
1997
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Gut hormone PYY3-36 physiologically inhibits food intake
2002 StandoutNature
A Novel Selective Melanocortin-4 Receptor Agonist Reduces Food Intake in Rats and Mice without Producing Aversive Consequences
2000
Interactions Between the Melanocortin System and Leptin in Control of Sympathetic Nerve Traffic
1999
The Hypothalamic Control of the Menstrual Cycle and the Role of Endogenous Opioid Peptides
1984
ZnT-3, a putative transporter of zinc into synaptic vesicles
1996
Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase.
1996 StandoutNobel
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
2000 StandoutScience
Chemical characterization of leptin-activated neurons in the rat brain
2000
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Neuroendocrine Control of Growth Hormone Secretion
1999
Role of leptin in hypothalamic–pituitary function
1997
Works of Robert A. Steiner being referenced
Diurnal Rhythm in Proopiomelanocortin mRNA in the Arcuate Nucleus of the Male Rat
1994
Pubertal changes in pro-opiomelanocortin and gonadotropin-releasing hormone gene expression in the brain of the male monkey
1991
Galanin overexpressing transgenic mice
2002
Simultaneous visualization of two cellular mRNA species in individual neurons by use of a new double in Situ hybridization method
1992
KiSS‐1 Neurones Are Direct Targets for Leptin in the ob/ob Mouse
2006
Short-Term Starvation Decreases POMC mRNA but Does Not Alter GnRH mRNA in the Brain of Adult Male Rats
1992
Inhibition of Steroid‐Induced Galanin mRNA Expression in GnRH Neurons by Specific NMDA‐Receptor Blockade
1996
Sexual Dimorphism of Growth Hormone-Releasing Hormone and Somatostatin Gene Expression in the Hypothalamus of the Rat During Development*
1991
Leptin's Actions on the Reproductive Axis: Perspectives and Mechanisms
1999
Sexual Dimorphism and Testosterone-Dependent Regulation of Somatostatin Gene Expression in the Periventricular Nucleus of the Rat Brain*
1989
Growth Hormone-Releasing Hormone Messenger Ribonucleic Acid in the Hypothalamus of the Adult Male Rat Is Increased by Testosterone*
1990
Pubertal Changes in Gonadotropin-Releasing Hormone and Proopiomelanocortin Gene Expression in the Brain of the Male Rat*
1989
Effect of Fasting, Refeeding, and Dietary Fat Restriction on Plasma Leptin Levels1
1997
Proopiomelanocortin Neurons Are Direct Targets for Leptin in the Hypothalamus
1997
Regulation of somatostatin and growth hormone-releasing hormone gene expression in the rat brain
1990
Role of NPY Neurones in GH-Dependent Feedback Signalling to the Brain
1996
Distribution and regulation of galanin receptor 1 messenger RNA in the forebrain of wild type and galanin-transgenic mice
2003
The Effect of Hypophysectomy and Growth Hormone Administration on Pre-Prosomatostatin Messenger Ribonucleic Acid in the Periventricular Nucleus of the Rat Hypothalamus*
1988
Kisspepeptin-GPR54 signaling in the neuroendocrine reproductive axis
2006
The distribution of hypothalamic nitric oxide synthase mRNA in relation to gonadotrophin-releasing hormone neurons
1994
The Stimulatory Effect of Leptin on the Neuroendocrine Reproductive Axis of the Monkey1
1998
Inhibition of Gonadotropin Secretion in Castrated Male Rhesus Monkeys (Macaca mulatto) Induced by Dietary Restriction: Analogy with the Prepubertal Hiatus of Gonadotropin Release*
1986
Lords and ladies leapin' on leptin.
1996
Regulation of gonadotropin-releasing hormone (GnRH) and galanin gene expression in GnRH neurons during lactation in the rat.
1993
Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons.
1992
Somatostatin: A Physiological Role in the Regulation of Growth Hormone Secretion in the Adolescent Male Baboon*
1978
Differential role of melanocortins in mediating leptin's central effects on feeding and reproduction
2000
Cloning and Distribution of Galanin-Like Peptide mRNA in the Hypothalamus and Pituitary of the Macaque
2002
Identification of target cells for growth hormone's action in the arcuate nucleus
1995
Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat.
1993
Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat.
1996
Leptin is a metabolic signal to the reproductive system.
1996
Distribution of galaninergic immunoreactivity in the brain of the mouse
2001
The role of galanin and its receptor in the feedback regulation of growth hormone secretion.
1996
Regulation of Hypothalamic Proopiomelanocortin mRNA by Leptin in ob/ob Mice
1997
Progesterone Modulation of Pulsatile Luteinizing Hormone Secretion in Normal Women*
1984
The Role of Endogenous Gonadotropin-releasing Hormone in the Control of Luteinizing Hormone and Testosterone Secretion in the Juvenile Male Monkey, Macaca Fascicularis1
1985
Noradrenergic and Dopaminergic Regulation of GH and Prolactin in Baboons
1978
Animal models in human reproduction
1981
Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test
2003
Suppression of Plasma Gonadotropins and Testosterone in Adult Male Monke(Macaca fascicularis) by a Potent Inhibitory Analog of Gonadotropin-Releasing Hormone*
1986
Leptin Is a Metabolic Gate for the Onset of Puberty in the Female Rat
1997
Metabolic changes during maturation of male monkeys: possible signals for onset of puberty
1985
Vasoactive Intestinal Polypeptide Effects a Central Inhibition of Pulsatile Luteinizing Hormone Secretion in Ovariectomized Rats*
1985
Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease
2001
Reduced Preprosomatostatin Messenger Ribonucleic Acid in the Periventricular Nucleus of Hypophysectomized Rats Determined by Quantitative in Situ Hybridization*
1987