Standout Papers
Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Single-crystal x-ray diffraction structures of covalent organic frameworks
2018 StandoutScienceNobel
Palladium-catalyzed Suzuki–Miyaura cross-coupling reaction of potassium 2-pyridyl trifluoroborate with aryl (heteroaryl) halides
2011
Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function
2010 StandoutNobel
The Aldol Addition Reaction: An Old Transformation at Constant Rebirth
2002
N‐Trialkylsilylimines as Coupling Partners for Pd‐Catalyzed CN Bond‐Forming Reactions: One‐Step Synthesis of Imines and Azadienes from Aryl and Alkenyl Bromides
2003
A Convenient Procedure for the Palladium‐Catalyzed Cyanation of Aryl Halides
2003
Ammonia: An Environmentally Friendly Nitrogen Source for Primary Aniline Synthesis
2010
Azaborine Compounds for Organic Field‐Effect Transistors: Efficient Synthesis, Remarkable Stability, and BN Dipole Interactions
2013
Cross‐Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)
2011 StandoutNobel
Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists
2007
An N‐Heterocyclic Carbene Ligand with Flexible Steric Bulk Allows Suzuki Cross‐Coupling of Sterically Hindered Aryl Chlorides at Room Temperature
2003
Highly Enantioselective Hetero‐Diels–Alder Reaction of 1,3‐Bis(silyloxy)‐1,3‐dienes with Aldehydes Catalyzed by Chiral Disulfonimide
2012 StandoutNobel
Transmetalation in the Suzuki–Miyaura Coupling: The Fork in the Trail
2013
Carbon–heteroatom bond formation catalysed by organometallic complexes
2008 StandoutNature
Codon usage limitation in the expression of HIV-1 envelope glycoprotein
1996
Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling
2009
The Azaallylic Anion as a Synthon for Pd‐Catalyzed Synthesis of Heterocycles: Domino Two‐ and Three‐Component Synthesis of Indoles
2007
8-Fluoroimidazo[1,2-a]pyridine: Synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABAA receptor
2006
A General Palladium‐Catalyzed Amination of Aryl Halides with Ammonia
2009
Antitumour polycyclic acridines. Palladium(0 ) mediated syntheses of quino[4,3,2-kl]acridines bearing peripheral substituents as potential telomere maintenance inhibitors
2003
Direct Catalytic Asymmetric Enolexo Aldolizations
2003 StandoutNobel
Selection of boron reagents for Suzuki–Miyaura coupling
2013 Standout
The First Phosphine Oxide Ligand Precursors for Transition Metal Catalyzed Cross-Coupling Reactions: C−C, C−N, and C−S Bond Formation on Unactivated Aryl Chlorides
2001
A Powerful Chiral Counteranion Motif for Asymmetric Catalysis
2009 StandoutNobel
Orthopalladated and ‐platinated Bulky Triarylphosphite Complexes: Synthesis, Reactivity and Application as High‐Activity Catalysts for Suzuki and Stille Coupling Reactions
2003
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
A Convenient Oxime-Carbapalladacycle-Catalyzed Suzuki Cross-Coupling of Aryl Chlorides in Water
2002
Practical synthesis of new and highly efficient ligands for the Suzuki reaction of aryl chlorides
2003
The Mukaiyama Aldol Reaction: 40 Years of Continuous Development
2013
Acyclic amino acid-catalyzed direct asymmetric aldol reactions: alanine, the simplest stereoselective organocatalyst
2005
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
2010 StandoutNobel
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
2012 Standout
A Highly Versatile Catalyst System for the Cross‐Coupling of Aryl Chlorides and Amines
2009
Current progress in the asymmetric aldol addition reaction
2004
Widely Applicable Pd‐Catalyzed trans‐Selective Monoalkylation of Unactivated 1,1‐Dichloro‐1‐alkenes and Pd‐Catalyzed Second Substitution for the Selective Synthesis of E or Z Trisubstituted Alkenes
2005 StandoutNobel
Direct Asymmetric Intermolecular Aldol Reactions Catalyzed by Amino Acids and Small Peptides
2006
Suzuki–Miyaura Cross‐Coupling Reactions in Aqueous Media: Green and Sustainable Syntheses of Biaryls
2010
Atroposelective Synthesis of Axially Chiral Biaryl Compounds
2005 Standout
A Rationally Designed Universal Catalyst for Suzuki–Miyaura Coupling Processes
2004
The Catalytic Asymmetric Abramov Reaction
2014 StandoutNobel
Catalytic Organometallic Reactions of Ammonia
2010
From Dioxin to Drug Lead—The Development of 2,3,7,8‐Tetrachlorophenothiazine
2007
Synthesis of 7‐Aminocoumarin by Buchwald–Hartwig Cross Coupling for Specific Protein Labeling in Living Cells
2010
Delta agonist hydroxy bioisosteres: The discovery of 3-((1-benzylpiperidin-4-yl){4-[(diethylamino)carbonyl]phenyl}amino)benzamide with improved delta agonist activity and in vitro metabolic stability
2009
Advances in Functional‐Group‐Tolerant Metal‐Catalyzed Alkyl–Alkyl Cross‐Coupling Reactions
2003
Asymmetric Counteranion‐Directed Catalytic Hosomi–Sakurai Reaction
2012 StandoutNobel
Homogeneous Catalysts Supported on Soluble Polymers: Biphasic Suzuki–Miyaura Coupling of Aryl Chlorides Using Phase‐Tagged Palladium–Phosphine Catalysts
2004
Small peptides as modular catalysts for the direct asymmetric aldol reaction: ancient peptides with aldolase enzyme activity
2005
Efficient and recyclable dendritic Buchwald-type catalyst for the Suzuki reaction
2007
Catalytic, Enantioselective, Vinylogous Aldol Reactions
2005
BippyPhos: A Single Ligand With Unprecedented Scope in the Buchwald–Hartwig Amination of (Hetero)aryl Chlorides
2013
Sterically demanding trialkylphosphines for palladium-catalyzed cross coupling reactions—alternatives to PtBu3
2009
Asymmetric Synthesis of Antimicrotubule Biaryl Hybrids of Allocolchicine and Steganacin
2007
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
2008 Standout
A ferrocene based palladacyclic precatalyst for the Suzuki cross-coupling of aryl chlorides
2003
Asymmetric Sorting of Ash1p in Yeast Results from Inhibition of Translation by Localization Elements in the mRNA
2002
Diels–Alder Approach to Polysubstituted Biaryls: Rapid Entry to Tri‐ and Tetra‐ortho‐substituted Phosphorus‐Containing Biaryls
2006
Evidence for the Formation and Structure of Palladacycles during Pd‐Catalyzed CN Bond Formation with Catalysts Derived from Bulky Monophosphinobiaryl Ligands
2006
Progress in the Palladium‐Catalyzed Cyanation of Aryl Chlorides
2003
Carbon–carbon bonding made easy
2005 StandoutNobel
Rational Ligand Design in Constructing Efficient Catalyst Systems for Suzuki–Miyaura Coupling
2004
Palladium-Catalyzed Amidation of Aryl Halides Using 2-Dialkylphosphino-2′-alkoxyl-1,1′-binaphthyl as Ligands
2012
The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis
2001
Monoligated Palladium Species as Catalysts in Cross‐Coupling Reactions
2004
Atroposelective Synthesis of Axially Chiral Biaryl Compounds
2005
A modular route to nonracemic cyclo-NOBINs. Preparation of the parent ligand for homo- and heterogeneous catalysis
2004
Efficient Synthesis of Well-Defined, High Molecular Weight, and Processible Polyanilines under Mild Conditions via Palladium-Catalyzed Amination
2000
Syntheses and characterizations of methylpalladium complexes bearing a biphenyl-based bulky phosphine ligand: Weak interactions suggested by NBO and QTAIM analyses
2006
Highly Efficient Suzuki Coupling Reaction of α‐Chloroalkylidene‐β‐lactones and β‐Lactams with Organoboronic Acids
2006
Die katalysierte asymmetrische Aldolreaktion
2000
Cross-Coupling Reactions of Aromatic and Heteroaromatic Silanolates with Aromatic and Heteroaromatic Halides
2009
Synthesis of Tetra-ortho-substituted, Phosphorus-Containing and Carbonyl-Containing Biaryls Utilizing a Diels−Alder Approach
2007
Triazole-Based Monophosphines for Suzuki−Miyaura Coupling and Amination Reactions of Aryl Chlorides
2005
Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)–tricyclohexylphosphine complexes
2001
Mild conditions for Pd-catalyzed conversion of aryl bromides to primary anilines using benzophenone imine
2009
Distinguishing Between Pathways for Transmetalation in Suzuki−Miyaura Reactions
2011
Triazole-Based Monophosphine Ligands for Palladium-Catalyzed Cross-Coupling Reactions of Aryl Chlorides
2006
Palladium‐Catalyzed CN and CO Coupling–A Practical Guide from an Industrial Vantage Point†
2004
Simple, Efficient Catalyst System for the Palladium-Catalyzed Amination of Aryl Chlorides, Bromides, and Triflates
2000
New mechanistic studies on the proline-catalyzed aldol reaction
2004 StandoutNobel
Expedited Palladium-Catalyzed Amination of Aryl Nonaflates through the Use of Microwave-Irradiation and Soluble Organic Amine Bases
2005
Synthesis of 2D Imine-Linked Covalent Organic Frameworks through Formal Transimination Reactions
2017
Synthesis of a TRPV1 Receptor Antagonist
2009
Amination Reactions of Aryl Halides with Nitrogen-Containing Reagents Mediated by Palladium/Imidazolium Salt Systems
2001
The intramolecular Stille reaction
1999
Catalysts for Suzuki−Miyaura Coupling Processes: Scope and Studies of the Effect of Ligand Structure
2005 Standout
Suzuki–Miyaura cross-coupling of lithium n-alkylborates
2001
Palladium-Catalyzed Arylation of Fluoroalkylamines
2015
C2-Symmetric Copper(II) Complexes as Chiral Lewis Acids. Catalytic Enantioselective Aldol Additions of Silylketene Acetals to (Benzyloxy)acetaldehyde
1996 Standout
Organotrifluoroborate Hydrolysis: Boronic Acid Release Mechanism and an Acid–Base Paradox in Cross-Coupling
2012
Zinc Trimethylsilylamide as a Mild Ammonia Equivalent and Base for the Amination of Aryl Halides and Triflates
2005
An Improved Synthesis of Functionalized Biphenyl-Based Phosphine Ligands
2000
Cross-Coupling Reactions of Potassium Alkyltrifluoroborates with Aryl and 1-Alkenyl Trifluoromethanesulfonates
2001
The synthesis of potentially selective inhibitors of dihydroorotate dehydrogenase. The utilization of chemoselective Suzuki cross-coupling reactions in a parallel synthesis
2001
B-Alkyl Suzuki−Miyaura Cross-Coupling Reactions with Air-Stable Potassium Alkyltrifluoroborates
2003
Ag(I)-promoted Suzuki–Miyaura cross-couplings of n -alkylboronic acids
2001
Efficient Aldolase Catalytic Antibodies That Use the Enamine Mechanism of Natural Enzymes
1995 Science
N,N,N′,N′-Tetraalkyl-2,2′-dihydroxy-1,1′-binaphthyl-3,3′-dicarboxamides: Novel Chiral Auxiliaries for Asymmetric Simmons–Smith Cyclopropanation of Allylic Alcohols and for Asymmetric Diethylzinc Addition to Aldehydes
1997
The Potential of Palladacycles: More Than Just Precatalysts
2005
Kreuzkupplungen von Organoboranen: ein einfacher Weg zum Aufbau von C‐C‐Bindungen (Nobel‐Aufsatz)
2011 Nobel
Investigating the Effects of a Hydrolytically Stable Hapten and a Th1 Adjuvant on Heroin Vaccine Performance
2012
The Slow‐Release Strategy in Suzuki–Miyaura Coupling
2010
Rational Development of Practical Catalysts for Aromatic Carbon−Nitrogen Bond Formation
1998 Standout
Development of Preformed Pd Catalysts for Cross-Coupling Reactions, Beyond the 2010 Nobel Prize
2012
Palladium−Imidazolium Carbene Catalyzed Aryl, Vinyl, and Alkyl Suzuki−Miyaura Cross Coupling
2001
Asymmetric Lewis acid organocatalysis of the Diels–Alder reaction by a silylated C–H acid
2016 StandoutScienceNobel
Oxazaborolidinone-Promoted Vinylogous Mukaiyama Aldol Reactions
2007
Studies into diastereoselective Dötz benzannulations for the synthesis of axially chiral biaryls
2003
Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis
2002 Standout
Synthesis of α-Carbolines via Pd-Catalyzed Amidation and Vilsmeier−Haack Reaction of 3-Acetyl-2-chloroindoles
2011
Development of the Suzuki−Miyaura Cross-Coupling Reaction: Use of Air-Stable Potassium Alkynyltrifluoroborates in Aryl Alkynylations
2002
Versatile Catalysts for the Suzuki Cross-Coupling of Arylboronic Acids with Aryl and Vinyl Halides and Triflates under Mild Conditions
2000
Synthesis of (R)‐(–)‐2‐Fluoronorapomorphine — A Precursor for the Synthesis of (R)‐(–)‐2‐Fluoro‐N‐[11C]propylnorapomorphine for Evaluation as a Dopamine D2 Agonist Ligand for PET Investigations
2005
Synthesis of Enantiomerically Pure Dissymmetric 2,2'‐Disubstituted9,9'‐Spirobifluorenes
2005
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
A novel class of amide-derived air-stable P,O-ligands for Suzuki cross-coupling at low catalyst loading
2004
Carbon−Carbon Bond Forming Reactions Mediated by Silicon Lewis Acids
2003 Standout
N‐Trialkylsilylimines as Coupling Partners for Pd‐Catalyzed CN Bond‐Forming Reactions: One‐Step Synthesis of Imines and Azadienes from Aryl and Alkenyl Bromides
2003
PdCl2(SEt2)2 and Pd(OAc)2: simple and efficient catalyst precursors for the Suzuki cross-coupling reaction
2000
High-Throughput Screening Studies of Fiber-Supported Catalysts Leading to Room-Temperature Suzuki Coupling
2002
Catalytic Asymmetric Coupling of 2-Naphthols by Chiral Tridentate Oxovanadium(IV) Complexes
2001
Industrial‐Scale Palladium‐Catalyzed Coupling of Aryl Halides and Amines –A Personal Account
2006
Synthesis of substituted tetrahydrofuranones and tetrahydropyranones: Photocycloaddition/fragmentation reactions of dioxinones
1997
Extremely Active Organocatalysts Enable a Highly Enantioselective Addition of Allyltrimethylsilane to Aldehydes
2016 StandoutNobel
A Highly Active Suzuki Catalyst for the Synthesis of Sterically Hindered Biaryls: Novel Ligand Coordination
2002
Unusual Preference for Ketone and Reversal of Chemoselectivity in Lewis Acid-Catalyzed Aldol Reaction of Ketene Silyl Acetal
1998
Übergangsmetall-katalysierte Synthese von Arylaminen und Arylethern aus Arylhalogeniden und -triflaten: Anwendungen und Reaktionsmechanismus
1998
Development of a Scalable Synthesis of a Bruton’s Tyrosine Kinase Inhibitor via C–N and C–C Bond Couplings as an End Game Strategy
2013
Molecularly defined palladium(0) monophosphine complexes as catalysts for efficient cross-coupling of aryl chlorides and phenylboronic acid1
2000
Selective Palladium-Catalyzed Arylation of Ammonia: Synthesis of Anilines as Well as Symmetrical and Unsymmetrical Di- and Triarylamines
2007
o,p-Polyaniline: A New Form of a Classic Conducting Polymer
2003
Suzuki Cross-Coupling Reactions Catalyzed by Palladium Nanoparticles in Aqueous Solution
2000
Orthogonal Reactivity in Boryl-Substituted Organotrifluoroborates
2008
Pd/C as a Reusable Catalyst for the Coupling Reaction of Halophenols and Arylboronic Acids in Aqueous Media
2002
Disulfonimid‐katalysierte asymmetrische vinyloge und bisvinyloge Mukaiyama‐Aldolreaktionen
2010 StandoutNobel
Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions of Potassium Aryl- and Heteroaryltrifluoroborates
2003
Suzuki–Miyaura cross-coupling of aryl and alkyl halides using palladium/imidazolium salt protocols
2004
Development and Applications of Disulfonimides in Enantioselective Organocatalysis
2015 StandoutNobel
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
Room-Temperature Pd-Catalyzed Amidation of Aryl Bromides Using tert-Butyl Carbamate
2009
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands
2008 Standout
Hydrogen Bond Catalyzed Enantioselective Vinylogous Mukaiyama Aldol Reaction
2005
Phosphines Having a 2,3,4,5-Tetraphenylphenyl Moiety: Effective Ligands in Palladium-Catalyzed Transformations of Aryl Chlorides
2006
Palladium-Catalyzed C–N Cross Coupling of Sulfinamides and Aryl Halides
2012
A General Method for the Synthesis of Unsymmetrically Substituted Ureas via Palladium-Catalyzed Amidation
2009
Aldolase Antibodies of Remarkable Scope
1998 StandoutNobel
The Complementary Competitors: Palladium and Copper in C–N Cross-Coupling Reactions
2012
Dechlorination of Aryl Chlorides with Sodium Formate Using a Homogeneous Palladium Catalyst
2006
Catalytic Enantioselective Addition of Allylic Organometallic Reagents to Aldehydes and Ketones
2003 Standout
Palladium-catalyzed biaryl-coupling reaction of arylboronic acids in water using hydrophilic phosphine ligands
2002
Katalytische enantioselektive vinyloge Aldolreaktionen
2005
Iron-Catalyzed Cross-Coupling Reactions of Alkyl-Grignard Reagents with Aryl Chlorides, Tosylates, and Triflates
2002
Regioselective acylation of 1-hydroxypyrazoles via metalated intermediates
2002
The First General Palladium Catalyst for the Suzuki−Miyaura and Carbonyl Enolate Coupling of Aryl Arenesulfonates
2003
Suzuki Cross-Coupling Reactions of Potassium Alkenyltrifluoroborates
2001
Aldolreaktionen in der Totalsynthese von Polyketiden
2006
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Boron Reagents in Process Chemistry: Excellent Tools for Selective Reductions
2006
Base-Mediated Reaction of Hydrazones and Nitroolefins with a Reversed Regioselectivity: A Novel Synthesis of 1,3,4-Trisubstituted Pyrazoles
2008
The formyl C–H⋯O hydrogen bond as a critical factor in enantioselective Lewis-acid catalyzed reactions of aldehydes
2001 Nobel
Utilization of Potassium Vinyltrifluoroborate in the Development of a 1,2-Dianion Equivalent
2009
Modern Aldol Methods for the Total Synthesis of Polyketides
2006
Synthesis of new tetracyclic azaheteroaromatic cores via auto-tandem Pd-catalyzed and one-pot Pd- and Cu-catalyzed double C–N bond formation
2010
Fluorous-Tagged Carbamates for the Pd-Catalyzed Amination of Aryl Halides
2007
An Improved Method for the Palladium-Catalyzed Amination of Aryl Iodides
2001
Optimisation of Permanganate Oxidation and Suzuki−Miyaura Coupling Steps in the Synthesis of a Nav1.8 Sodium Channel Modulator
2009
Synthesis and Opioid Receptor Binding Affinities of 2-Substituted and 3-Aminomorphinans: Ligands for μ, κ, and δ Opioid Receptors
2009
Palladium-catalysed reactions of aryl halides with soft, non-organometallic nucleophiles
2002
Single Component Self‐Assembled Monolayers of Aromatic Azo‐Biphenyl: Influence of the Packing Tightness on the SAM Structure and Light‐Induced Molecular Movements
2008 StandoutNobel
High‐Turnover Palladium Catalysts in Cross‐Coupling and Heck Chemistry: A Critical Overview
2004
Supported Ionic Liquids. New Recyclable Materials for the L ‐Proline‐Catalyzed Aldol Reaction
2006
Apparent Catalytic Generation of Chiral Metal Enolates: Enantioselective Dienolate Additions to Aldehydes Mediated by Tol-BINAP·Cu(II) Fluoride Complexes
1998
Highly Active and Selective Catalysts for the Formation of α-Aryl Ketones
2000
Efficient aqueous-phase Suzuki coupling of activated aryl chlorides with arylboronic acids using d-glucosamine-based dicyclohexylarylphosphine
2005
Palladium-catalyzed arylation of N,N-dialkylhydrazines and the subsequent conversion to anilines
2007
One-Pot Synthesis of Unsymmetrical Triarylamines from Aniline Precursors
2000
Palladium–tetraphosphine catalysed cross coupling of aryl bromides with arylboronic acids: remarkable influence of the nature of the ligand
2001
Palladium-Catalyzed Synthesis of Arylamines from Aryl Halides and Lithium Bis(trimethylsilyl)amide as an Ammonia Equivalent
2001
Poly(1,1‘-bi-2-naphthol)s: Synthesis, Characterization, and Application in Lewis Acid Catalysis
1996
Organotrifluorborate und einfach koordinierte Palladiumkomplexe als Katalysatoren – die perfekte Kombination für die Suzuki‐Miyaura‐Kupplung
2009
Dialkylphosphinoimidazoles as New Ligands for Palladium‐Catalyzed Coupling Reactions of Aryl Chlorides
2004
Catalyzed enantioselective aldol additions of latent enolate equivalents
1998
Palladium bis(phosphinite) ‘PCP’-pincer complexes and their application as catalysts in the Suzuki reaction
2000
Palladium Catalysis for the Synthesis of Hydrophobic C-6 and C-2 Aryl 2‘-Deoxynucleosides. Comparison of C−C versus C−N Bond Formation as well as C-6 versus C-2 Reactivity
2001
Proline-Catalyzed Direct Asymmetric Aldol Reactions
2000 StandoutNobel
Remarkable Enhancement of Catalyst Activity of Trialkylsilyl Sulfonates on the Mukaiyama Aldol Reaction: A New Approach Using Bulky Organoaluminum Cocatalysts
1998
A convenient and efficient procedure for the palladium-catalyzed cyanation of aryl halides using trimethylsilylcyanide
2003
Asymmetric Synthesis of an Axially Chiral Antimitotic Biaryl via an Atropo-Enantioselective Suzuki Cross-Coupling
2003
An Efficient Synthesis of N‐(Hetero)arylcarbazoles: Palladium‐Catalyzed Coupling Reaction between (Hetero)aryl Chlorides and N‐Carbazolylmagnesium Chloride
2015
Einfach koordinierte Palladiumspezies als Katalysatoren in Kreuzkupplungen
2004
On the Nature of the Active Species in Palladium Catalyzed Mizoroki–Heck and Suzuki–Miyaura Couplings – Homogeneous or Heterogeneous Catalysis, A Critical Review
2006 Standout
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
2018 StandoutScienceNobel
Palladium-Catalyzed C−N Bond Formation: Facile and General Synthesis of N6-Aryl 2‘-Deoxyadenosine Analogues
1999
A New Highly Efficient Catalyst System for the Coupling of Nonactivated and Deactivated Aryl Chlorides with Arylboronic Acids
2000
Palladium-catalyzed amination of aryl halides and sulfonates
1999
Investigations into ambient temperature biaryl coupling reactions
1997
Palladacycles in catalysis – a critical survey
2004
Synthesis of functionalized hydroxy-thiophene motifs as amido- and sulfonamido-phenol bioisosteres
2009
A Catalytic Asymmetric Suzuki Coupling for the Synthesis of Axially Chiral Biaryl Compounds
2000
Efficient Synthesis of N-Aryl-Aza-Crown Ethers via Palladium-Catalyzed Amination
2000
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
A Rationally Designed Universal Catalyst for Suzuki–Miyaura Coupling Processes
2004
Selective catch and release of a synthetically useful phosphine ligand
2003
DieB-Alkyl-Suzuki-Miyaura-Kreuzkupplung: Entwicklung, Untersuchungen zum Mechanismus und Anwendungen in der Naturstoffsynthese
2001
Application of Selective Palladium‐Mediated Functionalization of the Pyrido[3′,2′:4,5]pyrrolo[1,2‐c]pyrimidine Heterocyclic System for the Total Synthesis of Variolin B and Deoxyvariolin B
2010
Ionic Liquid (Molten Salt) Phase Organometallic Catalysis
2002 Standout
Air Stable, Sterically Hindered Ferrocenyl Dialkylphosphines for Palladium-Catalyzed C−C, C−N, and C−O Bond-Forming Cross-Couplings
2002
Atom-Efficient Metal-Catalyzed Cross-Coupling Reaction of Indium Organometallics with Organic Electrophiles
2001
Insights into Amine Binding to Biaryl Phosphine Palladium Oxidative Addition Complexes and Reductive Elimination from Biaryl Phosphine Arylpalladium Amido Complexes via Density Functional Theory
2007
Mild Pd-Catalyzed N-Arylation of Methanesulfonamide and Related Nucleophiles: Avoiding Potentially Genotoxic Reagents and Byproducts
2011
Palladium-catalysed synthesis of biaryl phosphines
2004
Lewis Base Activation of Lewis Acids. Vinylogous Aldol Reactions
2003
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Convenient Synthesis of 1H‐Indol‐1‐yl Boronates via Palladium(0)‐Catalyzed Borylation of Bromo‐1H‐indoles with ‘Pinacolborane’
2006
IDPi Catalysis
2019 StandoutNobel
Generating Active “L-Pd(0)” via Neutral or Cationic π-Allylpalladium Complexes Featuring Biaryl/Bipyrazolylphosphines: Synthetic, Mechanistic, and Structure–Activity Studies in Challenging Cross-Coupling Reactions
2015
Palladium‐catalyzed amination with benzophenone imine as a new, safe and practical alternative to nitration for the synthesis of 7‐amino‐2,1,3‐benzothiadiazoles
2003
A Powerful Chiral Counteranion Motif for Asymmetric Catalysis
2009 StandoutNobel
Suzuki cross-coupling of aryl halides with aryl boronic acids catalyzed by phosphine-free NiCl2·6H2O
2002
Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization
2005
Development of Two Complementary Syntheses for a Privileged CGRP Receptor Antagonist Substructure
2012
Fluorotitanium Compounds—Novel Catalysts for the Addition of Nucleophiles to Aldehydes
1997
Diastereoselection in Lewis-Acid-Mediated Aldol Additions
1999
Advances in the Heck chemistry of aryl bromides and chlorides
2001
Highly stereospecific conversion of planar chirality of a cyclophane into axial chirality of binaphthyls
1996
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
14C-Labeled and Large-Scale Synthesis of the Angiotensin-(1−7)-receptor Agonist AVE 0991 by Cross-Coupling Reactions
2003
Highly Active Oxime-Derived Palladacycle Complexes for Suzuki−Miyaura and Ullmann-Type Coupling Reactions
2002
Use of Polymer-Supported Dialkylphosphinobiphenyl Ligands for Palladium-Catalyzed Amination and Suzuki Reactions
2001
Anionic Amino Acid [closo-1-CB9H8-1-COO-10-NH3]− and Dinitrogen Acid [closo-1-CB9H8-1-COOH-10-N2] as Key Precursors to Advanced Materials: Synthesis and Reactivity
2009
Activation of olefins via asymmetric Brønsted acid catalysis
2018 StandoutScienceNobel
Direct Catalytic Asymmetric Aldol Reactions of Aldehydes with Unmodified Ketones
1997
Catalytic Asymmetric Vinylation of Ketone Enolates
2001
Room-Temperature Palladium-Catalyzed Amination of Aryl Bromides and Chlorides and Extended Scope of Aromatic C−N Bond Formation with a Commercial Ligand
1999
Carbon−Carbon Bond Formations Involving Organochromium(III) Reagents
1999
Highly Reactive, General and Long-Lived Catalysts for Palladium-Catalyzed Amination of Heteroaryl and Aryl Chlorides, Bromides, and Iodides: Scope and Structure–Activity Relationships
2008
Regioselective Synthesis of 1,3,5-Tri- and 1,3,4,5-Tetrasubstituted Pyrazoles from N-Arylhydrazones and Nitroolefins
2008
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Target-Directed Synthesis of Antibacterial Drug Candidate GSK966587
2010
Synthesis of Imidazo[4,5-b]pyridines and Imidazo[4,5-b]pyrazines by Palladium Catalyzed Amidation of 2-Chloro-3-amino-heterocycles
2012
Palladium-Catalyzed Amination of Aryl Nonaflates
2003
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis
2000
A Dicoordinate Palladium(0) Complex with an Unusual Intramolecular η-Arene Coordination
2003
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Palladium‐Iminodiacetic Acid Immobilized on pH‐Responsive Polymeric Microspheres: Efficient Quasi‐Homogeneous Catalyst for Suzuki and Heck Reactions in Aqueous Solution
2008
Evidence for the Formation and Structure of Palladacycles during Pd‐Catalyzed CN Bond Formation with Catalysts Derived from Bulky Monophosphinobiaryl Ligands
2006
Lewis Base Activation of Lewis Acids: Catalytic, Enantioselective Addition of Silyl Ketene Acetals to Aldehydes
2005
NiCl2(PCy3)2: A Simple and Efficient Catalyst Precursor for the Suzuki Cross-Coupling of Aryl Tosylates and Arylboronic Acids
2001
Palladium−Phosphinous Acid-Catalyzed Cross-Coupling of Aryl and Acyl Halides with Aryl-, Alkyl-, and Vinylzinc Reagents
2008
Asymmetric Enamine Catalysis
2007 StandoutNobel
Asymmetric Suzuki cross-coupling reaction: chirality reversal depending on the palladium–chiral phosphine ratio
2002
Bioinspired Synthesis of a Sedaxane Metabolite Using Catalytic Vanadyl Acetylacetonate and Molecular Oxygen
2015
Palladium-Catalyzed Coupling of Ammonia and Lithium Amide with Aryl Halides
2006
Diels–Alder Approach to Polysubstituted Biaryls: Rapid Entry to Tri‐ and Tetra‐ortho‐substituted Phosphorus‐Containing Biaryls
2006
The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver
2000 Standout
Copper- and Palladium-Catalyzed Amidation Reactions for the Synthesis of Substituted Imidazo[4,5-c]pyridines
2014
Synthesis of biaryls by intramolecular radical transfer: use of phosphinates
2000
Noncytopathic Sindbis virus RNA vectors for heterologous gene expression
1998 StandoutNobel
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Extremely Active Organocatalysts Enable a Highly Enantioselective Addition of Allyltrimethylsilane to Aldehydes
2016 StandoutNobel
Catalytic Asymmetric Vinylogous Mukaiyama-Aldol (CAVM) Reactions: The Enolate Activation
2001
Ein neues hocheffizientes Katalysatorsystem für die Kupplung von nichtaktivierten und desaktivierten Arylchloriden mit Arylboronsäuren
2000
Cross‐Coupling of Triallyl(aryl)silanes with Aryl Bromides and Chlorides: An Alternative Convenient Biaryl Synthesis
2004
Sulfur-Containing Palladacycles: Efficient Phosphine-Free Catalyst Precursors for the Suzuki Cross-Coupling Reaction at Room Temperature
2000
Introduction of Allyl and Prenyl Side‐Chains into Aromatic Systems by Suzuki Cross‐Coupling Reactions
2009
One-Pot Synthesis of N-Arylpyrazoles from Arylhalides
2009
1,1‘-Binaphthyl Dimers, Oligomers, and Polymers: Molecular Recognition, Asymmetric Catalysis, and New Materials
1998 Standout
Carbamic acid 2-trimethylsilylethyl ester as a new ammonia equivalent for palladium-catalyzed amination of aryl halides
2010
Triarylcarbenium Chlorides as Catalysts in Allylation Reaction: A Unique Type of Reaction with Negligible Intervention of Silyl Catalysis
1999
Iron-Catalyzed Cross-Coupling Reactions
2002
Reagent control of cram-type selectivity in the mukaiyama aldol catalysed by supersilylating agents
1995
A Palladium-Catalyzed Strategy for the Preparation of Indoles: A Novel Entry into the Fischer Indole Synthesis
1998
Completely N1-Selective Palladium-Catalyzed Arylation of Unsymmetric Imidazoles: Application to the Synthesis of Nilotinib
2011
The Azaallylic Anion as a Synthon for Pd‐Catalyzed Synthesis of Heterocycles: Domino Two‐ and Three‐Component Synthesis of Indoles
2007
Catalytic asymmetric allylation of aldehydes with BINOL-Ti(IV) complex accelerated by i-PrSSiMe3
1996
Tetraphosphine/palladium catalysed Suzuki cross-coupling reactions of aryl halides with alkylboronic acids
2004
The formyl CH--O hydrogen bond as a key to transition-state organization in enantioselective allylation, aldol and Diels-Alder reactions catalyzed by chiral lewis acids
1997 Nobel
Works of Robert A. Singer being referenced
Determinants of mRNA localization
1992
Total Synthesis of Macrolactin A with Versatile Catalytic, Enantioselective Dienolate Aldol Addition Reactions
1998
Totalsynthese von Makrolactin A über vielseitige katalytische, enantioselektive Dienolat-Aldoladditionen
1998
Highly Active Palladium Catalysts for Suzuki Coupling Reactions
1999
Synthesis of a Tridentate Ligand for Use in TiIV‐Catalyzed Acetate Aldol Addition Reactions
2003
Streamlined Synthesis of the Bippyphos Family of Ligands and Cross-Coupling Applications
2008
Catalytic, Enantioselective Aldol Additions with Methyl and Ethyl Acetate O-Silyl Enolates: A Chiral Tridentate Chelate as a Ligand for Titanium(IV)
1994
Catalytic, Enantioselective Dienolate Additions to Aldehydes: Preparation of Optically Active Acetoacetate Aldol Adducts
1995
An Ammonia Equivalent for the Palladium-Catalyzed Amination of Aryl Halides and Triflates
1997
Synthesis and Purification of 6-Ethoxy-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic Acid Benzylamide
2003
Catalytic, Enantioselective Acetone Aldol Additions with 2-Methoxypropene
1995
Alternative Biarylphosphinesfor Use in the Palladium-Catalyzed Amination of Aryl Halides
2003
Metal versus silyl triflate catalysis in the Mukaiyama aldol addition reaction
1994
Discovery and synthesis of novel phosphine-based ligands for aryl aminations
2004
Preparation of 2-amino-2′-hydroxy-1,1′-binaphthyl and N-arylated 2-amino-1,1′-binaphthyl derivatives via palladium-catalyzed amination
1999
Advances in catalytic, enantioselective aldol addition reactions with novel Ti(IV) complexes
1996
An in situ procedure for catalytic, enantioselective acetate aldol addition. Application to the synthesis of (R)-(−)-epinephrine
1997
Development of nonproprietary phosphine ligands for the Pd-catalyzed amination reaction
2006
A General Synthesis of End-Functionalized Oligoanilines via Palladium-Catalyzed Amination
1998
Palladium-Catalyzed Synthesis of Monodisperse, Controlled-Length, and Functionalized Oligoanilines
1998