Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Origins of Specificity in Protein-DNA Recognition
2010
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
MDC1: The art of keeping things in focus
2010
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
A De Novo Protein Binding Pair By Computational Design and Directed Evolution
2011 StandoutNobel
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Engineering proteins that bind, move, make and break DNA
2003 StandoutNobel
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Design of protein-interaction specificity gives selective bZIP-binding peptides
2009 Nature
Flopping polypeptide chains and Suleika's subtle imperfections: analysis of variations in the electron micrograph of a purple membrane crystal
1993 StandoutNobel
Multistate Protein Design Using CLEVER and CLASSY
2013
Protein Crystallization on Lipid Layers and Structure Determination of the RNA Polymerase II Transcription Initiation Complex
1999 StandoutNobel
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
2011 Nature
A de novo peptide hexamer with a mutable channel
2011
BCL-2 family proteins: changing partners in the dance towards death
2017
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
2012 StandoutNobel
The cellular response to DNA damage: A focus on MDC1 and its interacting proteins
2010
Principles for designing ideal protein structures
2012 StandoutNatureNobel
A de novo designed protein–protein interface
2007
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System
2013
ClpP Mediates Activation of a Mitochondrial Unfolded Protein Response in C. elegans
2007
Repair of Strand Breaks by Homologous Recombination
2013
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases
2008 Nature
The coming of age of de novo protein design
2016 StandoutNatureNobel
The DNA Damage Response: Ten Years After
2007
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Foundations for engineering biology
2005 StandoutNature
Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets
2005
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
A Simple Physical Model for the Prediction and Design of Protein–DNA Interactions
2004 StandoutNobel
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities
2003
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Protein binding specificity versus promiscuity
2010
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response
2009
Deriving Heterospecific Self-Assembling Protein–Protein Interactions Using a Computational Interactome Screen
2015
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
2006
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions
2012
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
2005 Nature
Protein delivery into eukaryotic cells by type III secretion machines
2006 Nature
Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein−Protein Interface
2006 StandoutNobel
Computer-aided design of functional protein interactions
2009
RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
2007
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Multistate approaches in computational protein design
2012
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Genome editing with engineered zinc finger nucleases
2010 Standout
Design of protein conformational switches
2006
VMD: Visual molecular dynamics
1996 Standout
Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments
2013
Energetics-based Protein Profiling on a Proteomic Scale: Identification of Proteins Resistant to Proteolysis
2007
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
Synthetic protein–protein interaction domains created by shuffling Cys 2 His 2 zinc‐fingers
2006
MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks
2008
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Molecular Determinants of Bim(BH3) Peptide Binding to Pro-Survival Proteins
2012
Targeted Chromosomal Cleavage and Mutagenesis in Drosophila Using Zinc-Finger Nucleases
2002
SYNZIP Protein Interaction Toolbox: in Vitro and in Vivo Specifications of Heterospecific Coiled-Coil Interaction Domains
2012
Increasing the affinity of selective bZIP‐binding peptides through surface residue redesign
2014
Modulation of Coiled-Coil Dimer Stability through Surface Residues while Preserving Pairing Specificity
2017
Envelope structure of Semliki Forest virus reconstructed from cryo-electron micrographs
1986 StandoutNatureNobel
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Squaring the Circle in Peptide Assembly: From Fibers to Discrete Nanostructures by de Novo Design
2012
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
2016 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer
2011
A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
2012
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
2009
COMPUTER-BASED DESIGN OF NOVEL PROTEIN STRUCTURES
2005
Electron microscopy of frozen-hydrated biological material
1986 Nature
Thromboxane generation by human peripheral blood polymorphonuclear leukocytes.
1978 StandoutNobel
Phospho‐dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage
2008
Is Cytosolic Ionized Calcium Regulating Neutrophil Activation?
1983 StandoutScienceNobel
Enhancing Gene Targeting with Designed Zinc Finger Nucleases
2003 Science
MDScope — a visual computing environment for structural biology
1995
The cellular response to DNA damage: A focus on MDC1 and its interacting proteins
2010
In vitro granulocyte adherence and in vivo margination: two associated complement-dependent functions
1977
An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks
2008
Evaluation of the Quality of Prognosis Studies in Systematic Reviews
2006
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Peptide Ligands for Pro-survival Protein Bfl-1 from Computationally Guided Library Screening
2013
Structure and Function of the Phosphothreonine-Specific FHA Domain
2008
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Orthogonal Synthetic Zippers as Protein Scaffolds
2018
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Oligomerization of MDC1 Protein Is Important for Proper DNA Damage Response
2011
The Measurement of Observer Agreement for Categorical Data
1977 Standout
Quantitative NMR spectroscopy of supramolecular complexes: Dynamic side pores in ClpP are important for product release
2005
A Set of de Novo Designed Parallel Heterodimeric Coiled Coils with Quantified Dissociation Constants in the Micromolar to Sub-nanomolar Regime
2013
Works of Robert A. Grant being referenced
Crystal Structure of the Catalytic Core of an RNA-Polymerase Ribozyme
2009 Science
Structure of a Designed Dimeric Zinc Finger Protein Bound to DNA ,
2003
Specificity versus stability in computational protein design
2005
Aggregation and Release Reaction Induced in Human Blood Platelets by Zymosan
1974
A Structural Basis for 14-3-3σ Functional Specificity*♦
2005
Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA.
2001
Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL
2010
Patch averaging of electron images of GP32∗I crystals with variable thickness
1992
The crystal structure of Dps, a ferritin homolog that binds and protects DNA
1998
Sculpting the Proteome with AAA+ Proteases and Disassembly Machines
2004
Mcl‐1–Bim complexes accommodate surprising point mutations via minor structural changes
2010
Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design
1994
Incidence studies of primary and secondary intracranial tumors: A systematic review of their methodology and results
1998
RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
2007
Beyond the “Recognition Code”
2001
Exploring the Role of Glutamine 50 in the Homeodomain−DNA Interface: Crystal Structure of Engrailed (Gln50 → Ala) Complex at 2.0 Å,
2000
Specimen preparative methods for electron crystallography of soluble proteins
1984
Requirement for Complement Components and Fibrinogen in the Zymosan-Induced Release Reaction of Human Blood Platelets
1974
A Synthetic Coiled-Coil Interactome Provides Heterospecific Modules for Molecular Engineering
2010
Design and Selection of Novel Cys2His2 Zinc Finger Proteins
2001