Citation Impact
Citing Papers
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Inflammation and cancer
2002 StandoutNature
Regulation of the differentiation and function of osteoclasts
2000
Proteolytic Activity of Human Osteoclast Cathepsin K
1996
Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo
1999 Standout
Expression of osteopontin messenger RNA and protein in rheumatoid arthritis: Effects of osteopontin on the release of collagenase 1 from articular chondrocytes and synovial fibroblasts
2000
Osteopontin expression and function: Role in bone remodeling
1998
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Osteopontin at mineralized tissue interfaces in bone, teeth, and osseointegrated implants: Ultrastructural distribution and implications for mineralized tissue formation, turnover, and repair
1996
Functions of Cathepsin K in Bone Resorption
2002
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) Apoptosis Systems
2000
Role of RANK ligand in mediating increased bone resorption in early postmenopausal women
2003
Can the pharmaceutical industry reduce attrition rates?
2004 Standout
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion
2000
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL
2005
Wnt signaling in osteoblasts and bone diseases
2004
The Hallmarks of Cancer
2000 Standout
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
Raloxifene, a Selective Estrogen Receptor Modulator, Reduces Carrageenan-Induced Acute Inflammation in Normal and Ovariectomized Rats
2005
High levels of osteoprotegerin and soluble receptor activator of nuclear factor κB ligand in serum of rheumatoid arthritis patients and their normalization after anti–tumor necrosis factor α treatment
2002
Osteoporosis: now and the future
2011 Standout
Lysosomal cysteine proteases: more than scavengers
2000
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
1997 StandoutNature
The biochemistry of apoptosis
2000 StandoutNature
Safety and antitumor activity of recombinant soluble Apo2 ligand
1999 Standout
RANK is essential for osteoclast and lymph node development
1999
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Advances in osteoclast biology: old findings and new insights from mouse models
2011
Regulation of osteoclast activity
1999
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Intraocular injection of tamoxifen‐loaded nanoparticles: a new treatment of experimental autoimmune uveoretinitis
2004
Drug-induced morphea: Report of a case induced by balicatib and review of the literature
2008
Differential effects of estrogen in the injured forebrain of young adult and reproductive senescent animals
2003
Targeting apoptosis in cancer therapy
2020 Standout
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
2002 Standout
Mechanical Loading Stimulates Differentiation of Periodontal Osteoblasts in a Mouse Osteoinduction Model: Effect on Type I Collagen and Alkaline Phosphatase Genes
2000
Osteopontin: a key cytokine in cell‐mediated and granulomatous inflammation
2000
β1 integrins and osteoclast function: Involvement in collagen recognition and bone resorption
1996
The Expression of Clcn7 and Ostm1 in Osteoclasts Is Coregulated by Microphthalmia Transcription Factor
2006
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Osteoclast differentiation and activation
2003 StandoutNature
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
2004 StandoutNature
Apoptosis control by death and decoy receptors
1999
Role of the α2-Integrin in Osteoblast-specific Gene Expression and Activation of the Osf2 Transcription Factor
1998
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Cancer immunotherapy comes of age
2011 StandoutNature
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Future directions of bone-targeted therapy for metastatic breast cancer
2010
Osteoprotegerin Ligand Modulates Murine Osteoclast Survival in Vitro and in Vivo
2000
Temporal Pattern of Stimulation of Osteoblast-Associated Genes During Mechanically-Induced OsteogenesisIn Vivo: Early Responses of Osteocalcin and Type I Collagen
2001
Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival
2001 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
The Calcium-Sensing Receptor: Physiology, Pathophysiology and Car-Based Therapeutics
2007
The O-glycomap of Lubricin, a Novel Mucin Responsible for Joint Lubrication, Identified by Site-specific Glycopeptide Analysis
2014
HLA association with autoimmune disease: a failure to protect?
2000
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Differential regulation of osteoblasts by substrate microstructural features
2004
Bone resorption induced by parathyroid hormone is strikingly diminished in collagenase-resistant mutant mice
1999
Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease
2004
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
2006
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
2002
Mechanisms of Anabolic Therapies for Osteoporosis
2007
The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor
1998 StandoutNobel
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
1998 Nature
The Complex Role of Estrogens in Inflammation
2007 Standout
The Protective Role of Endogenous Estrogens in Carrageenan-Induced Lung Injury in the Rat
2001
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Role of Osteopontin in Bone Remodeling Caused by Mechanical Stress
1999
To die or not to die—the quest of the TRAIL receptors
1999
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Osteopontin Facilitates Angiogenesis, Accumulation of Osteoclasts, and Resorption in Ectopic Bone*
2001
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2
1999 StandoutScience
Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency
1996 Science
Human mesenchymal stem cells modulate allogeneic immune cell responses
2004 Standout
The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone Resorption
2000
RANK Ligand and Osteoprotegerin
2002
A Single-Dose Placebo-Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women
2004
Bone Resorption by Osteoclasts
2000 StandoutScience
Estrogen Reduces the Depth of Resorption Pits by Disturbing the Organic Bone Matrix Degradation Activity of Mature Osteoclasts
2001
Structure and Design of Potent and Selective Cathepsin K Inhibitors
1997
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
2004
RANK-L and RANK: T Cells, Bone Loss, and Mammalian Evolution
2002
Death Receptors: Signaling and Modulation
1998 StandoutScience
Polymorphisms in the Osteoprotegerin Gene Are Associated With Osteoporotic Fractures
2002
Exploring and Engineering the Cell Surface Interface
2005 StandoutScience
Regulation of Osteoclast Function
1997
Parathyroid Hormone Stimulates TRANCE and Inhibits Osteoprotegerin Messenger Ribonucleic Acid Expression in Murine Bone Marrow Cultures: Correlation with Osteoclast-Like Cell Formation*
1999
An animal model for pycnodysostosis: the role of cathepsin K in bone remodelling
1999
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*
2000 Standout
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
THE LYSOSOMAL CYSTEINE PROTEASES
1999
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Update in New Anabolic Therapies for Osteoporosis
2010
Human Trabecular Bone Cells Are Able to Express Both Osteoblastic and Adipocytic Phenotype: Implications for Osteopenic Disorders
1998
Involvement of TRAIL and its receptors in viral hepatitis
2002
Guidelines for assessment of bone microstructure in rodents using micro–computed tomography
2010 Standout
Osteopontin Expression by Osteoclast and Osteoblast Progenitors in the Murine Bone Marrow: Demonstration of Its Requirement for Osteoclastogenesis and Its Increase After Ovariectomy*
1997
The Chloride Channel Inhibitor NS3736 Prevents Bone Resorption in Ovariectomized Rats Without Changing Bone Formation
2004
Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families
1999 Standout
Osteopontin
2000 Standout
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
The Integrin Ligand Echistatin Prevents Bone Loss in Ovariectomized Mice and Rats
1998
Role of RANK ligand in mediating increased bone resorption in early postmenopausal women
2003
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis
1996 StandoutNobel
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
2001 StandoutNobel
Caspases: Enemies Within
1998 StandoutScience
Therapeutic Approaches to Bone Diseases
2000 Science
α-Ketocarbonyl Peptides: A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support
2001 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
U0126 and PD98059, Specific Inhibitors of MEK, Accelerate Differentiation of RAW264.7 Cells into Osteoclast-like Cells
2002
Trafficking of Matrix Collagens Through Bone-Resorbing Osteoclasts
1997 Science
Molecular Dynamics Simulations of the Catalytic Pathway of a Cysteine Protease: A Combined QM/MM Study of Human Cathepsin K
2007
Works of Robert A. Dodds being referenced
Biosynthesis and processing of cathepsin K in cultured human osteoclasts
2001
Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries
2001
A selective inhibitor of the osteoclastic V-H+-ATPase prevents bone loss in both thyroparathyroidectomized and ovariectomized rats
2000
Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts
1996
Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL
1998
Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats
2000
Microcytophotometric analysis of human osteoclast metabolism: lack of activity in certain oxidative pathways indicates inability to sustain biosynthesis during resorption.
1994
Cathepsin K and the Design of Inhibitors of Cathepsin K
2000
FrzB-2: a human secreted frizzled-related protein with a potential role in chondrocyte apoptosis
2000
Induction and Expression of Human Cartilage Glycoprotein 39 in Rheumatoid Inflammatory and Peripheral Blood Monocyte-Derived Macrophages
1997
Studies of the route of administration and role of conditioning with radiation on unrelated allogeneic mismatched mesenchymal stem cell engraftment in a nonhuman primate model
2004
Expression of osteopontin mRNA by osteoclasts and osteoblasts in modelling adult human bone
1993
Idoxifene, a Novel Selective Estrogen Receptor Modulator, Is Effective in a Rat Model of Adjuvant-Induced Arthritis
1999
Applications of micro-CT and MR microscopy to study pre-clinical models of osteoporosis and osteoarthritis
1998
Cathepsin K mRNA Detection Is Restricted to Osteoclasts During Fetal Mouse Development
1998
Integrin subunit expression by human osteoblasts and osteoclasts in situ and in culture
1992
Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: An in vitro and ex vivo study of remodeling bone
1995
Antagonism of the Osteoclast Vitronectin Receptor with an Orally Active Nonpeptide Inhibitor Prevents Cancellous Bone Loss in the Ovariectomized Rat
2001
Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization
1999
Osteopontin deposition in remodeling bone: An osteoclast mediated event
1996
Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In Vivo
1997
Early loading-related changes in the activity of glucose 6-phosphate dehydrogenase and alkaline phosphatase in osteocytes and periosteal osteoblasts in rat fibulae in vivo
1993