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Citing Papers
H 2 S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase
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Identification of a Key Amino Acid of the β2-Adrenergic Receptor for High Affinity Binding of Salmeterol
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Chemistry for the analysis of protein–protein interactions: Rapid and efficient cross-linking triggered by long wavelength light
1999
Two Isoforms of the Prostaglandin E Receptor EP3 Subtype Different in Agonist-independent Constitutive Activity
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Prostaglandin Endoperoxide H Synthases-1 and -2
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Characterization of Functional Interaction of Carboxylic Acid Group of Agonists and Arginine of the Seventh Transmembrane Domains of Four Prostaglandin E Receptor Subtypes
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Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
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Prostaglandin E2Receptor Subtype EP2Gene Expression in the Mouse Uterus Coincides with Differentiation of the Luminal Epithelium for Implantation1
1997
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Chromosomal localization of the human prostanoid receptor gene family
1995
Cloning of the rat and human prostaglandin F2α receptors and the expression of the rat prostaglandin F2α receptor
1994
Molecular mechanisms of nociception
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Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation
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Long-Acting ??2-Agonists in Asthma
2006
Nucleotide signalling during inflammation
2014 StandoutNature
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
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Distribution and function of prostanoid receptors: studies from knockout mice
2000
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Thromboxane, Prostaglandin and Leukotriene Receptors
1989
Membrane depolarization by activation of prostaglandin E receptor EP3 subtype of putative serotonergic neurons in the dorsal raphe nucleus of the rat
1996
The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure
2001
Expression of messenger RNA for the prostaglandin D receptor in the leptomeninges of the mouse brain
1997
The role of IP prostanoid receptors in inflammatory pain
1998
Purinergic Signaling in the Airways
2012
Prostaglandin E2‐induced sensitization of bradykinin‐evoked responses in rat dorsal root ganglion neurons is mediated by cAMP‐dependent protein kinase A
2000
The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener
2001 Standout
A Primate-dominant Third Glycosylation Site of the β2-Adrenergic Receptor Routes Receptors to Degradation during Agonist Regulation
2004
Shifting Players and Paradigms in Cell-Specific Transcription
2009
Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig
1996
β3 and Atypical β‐Adrenoceptors
1993
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
2003 StandoutNature
The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth
1997 Nature
In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs
1995
Regulation of Prostaglandin F2αReceptor Expression in Cultured Human Granulosa-Luteal Cells1
1997
Structural visualization of key steps in human transcription initiation
2013 Nature
Selective Coupling of Prostaglandin E Receptor EP3D to Gi and Gs through Interaction of α-Carboxylic Acid of Agonist and Arginine Residue of Seventh Transmembrane Domain
1995
Prostaglandin E Receptor EP3 Subtype Induces Neurite Retraction via Small GTPase Rho
1996
Human housekeeping genes, revisited
2013
Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB
1999
Pregnancy Maintenance and Parturition: The Role of Prostaglandin in Manipulating the Immune and Inflammatory Response
1994
Structural Organization of the Human Prostaglandin EP3Receptor Subtype Gene (PTGER3)
1997
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Treatment of Asthma with Drugs Modifying the Leukotriene Pathway
1999
The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and Northern blot analysis
1995
Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme
2002
Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor
1999
Efficacy of antileukotriene agents in asthma management
2001
Characterization of the mouse prostaglandin F receptor gene: a transgenic mouse study of a regulatory region that controls its expression in the stomach and kidney but not in the ovary
1997
Cloning and expression of a cDNA for rat prostaglandin F2α receptor
1994
Prostacyclin receptor in the brain and central terminals of the primary sensory neurons: An autoradiographic study using a stable prostacyclin analogue [3H]iloprost
1995
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist
1993
Structure and mechanism of the RNA polymerase II transcription machinery
2004
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The development of allergic inflammation
2008 StandoutNature
Glial and neuronal control of brain blood flow
2010 StandoutNature
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition
2001 StandoutNobel
The Second Extracellular Loop of the Prostaglandin EP3 Receptor Is an Essential Determinant of Ligand Selectivity
1997
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Prostanoid Receptors of Murine NIH 3T3 and RAW 264.7 Cells
1996
Capillary pericytes regulate cerebral blood flow in health and disease
2014 StandoutNature
Serotonin signalling in the gut—functions, dysfunctions and therapeutic targets
2013
Rapid, Agonist-dependent Phosphorylation in Vivo of Human Thromboxane Receptor Isoforms
1997
Suppression of Prostaglandin E Receptor Signaling by the Variant Form of EP1 Subtype
1996
Prostaglandin endoperoxide synthases-1 and -2
1995
Identification of prostaglandin E receptor ‘EP2’ cloned from mastocytoma cells as EP4 subtype
1995
Molecular Cloning and Characterization of the Human Prostanoid DP Receptor
1995
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
What we can do and what we cannot do with fMRI
2008 StandoutNature
Immunolocalization of the Four Prostaglandin E2 Receptor Proteins EP1, EP2, EP3, and EP4 in Human Kidney
1999
Characterization of the LPS-Stimulated Expression of EP2 and EP4 Prostaglandin E Receptors in Mouse Macrophage-like Cell Line, J774.1
1998
Patent Ductus Arteriosus and Neonatal Death in Prostaglandin Receptor EP4-Deficient Mice
1998
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
Insight into prostaglandin, leukotriene, and other eicosanoid functions using mice with targeted gene disruptions☆
1999
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
The Role of the Seventh Transmembrane Region in High Affinity Binding of a β2-Selective Agonist TA-2005
1998
Using Oxidative Crosslinking and Proximity Labeling to Quantitatively Characterize Protein-Protein and Protein-Peptide Complexes
2003
The mechanisms of enhancement and inhibition of field stimulation responses of guinea‐pig vas deferens by prostacyclin analogues
1997
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells
1997
Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes
1997
Molecular evolution of receptors for eicosanoids
1995
‘Distinct Cellular Localization of the Messenger Ribonucleic Acid for Prostaglandin E Receptor Subtypes in the Mouse Uterus during Pseudopregnancy1
1997
Synthesis and properties of crosslinked recombinant pro-resilin
2005 StandoutNature
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
2004
TAFs revisited: more data reveal new twists and confirm old ideas
2000
The classification of prostaglandin DP‐receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist
1989
Perivascular nerves and the regulation of cerebrovascular tone
2006
Characterisation of the EP-receptor mediating dilatation and potentiation of inflammation in rabbit skin
1995
The β -Adrenoceptor
1998
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
2004 StandoutNobel
Oxidative inactivation of leukotriene C 4 by stimulated human polymorphonuclear leukocytes
1982 StandoutNobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Genetics of Mouse Behavior: Interactions with Laboratory Environment
1999 StandoutScience
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Urinary concentrating function in mice lacking EP3receptors for prostaglandin E2
1998
Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.
1996
EFFECTS OF PROSTAGLANDINS AND THROMBOXANE ANALOGUES ON BULLOCK AND DOG IRIS SPHINCTER PREPARATIONS
1982
Identification of a key amino acid of the beta2-adrenergic receptor for high affinity binding of salmeterol.
1998
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Characterization of the gene for the mouse prostaglandin E receptor subtype EP2: tissue-specific initiation of transcription in the macrophage and the uterus
1998
Titania-Catalyzed Radiofluorination of Tosylated Precursors in Highly Aqueous Medium
2015
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2
1999
MOLECULAR MECHANISMS OF PROSTAGLANDIN TRANSPORT
1998
Cloning and expression of a cDNA for mouse prostaglandin F receptor.
1994
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Modulation of TTX-RINaby PKC and PKA and Their Role in PGE2-Induced Sensitization of Rat Sensory NeuronsIn Vitro
1998
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.
1993
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Comparative pyrogenic potency of endogenous prostanoids and of prostanoid-mimetics injected into the anterior hypothalamic/preoptic region of the cat
1988
Fission Yeast Homologs of Human CENP-B Have Redundant Functions Affecting Cell Growth and Chromosome Segregation
2000
The mast cell and allergic diseases: role in pathogenesis and implications for therapy
2007
Asymmetric Transfer Hydrogenation of α, β-Acetylenic Ketones
1997 StandoutNobel
ANTAGONISM OF THE THROMBOXANE‐SENSITIVE CONTRACTILE SYSTEMS OF THE RABBIT AORTA, DOG SAPHENOUS VEIN AND GUINEA‐PIG TRACHEA
1982
Crucial Involvement of the EP4 Subtype of Prostaglandin E Receptor in Osteoclast Formation by Proinflammatory Cytokines and Lipopolysaccharide
2000
Pharmacological Inhibition of Protein Kinases in Intact Cells: Antagonism of Beta Adrenergic Receptor Ligand Binding by H-89 Reveals Limitations of Usefulness
1999
Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.
1993
Purification of the thromboxane A2/prostaglandin H2 receptor from human blood platelets
1989
Responsiveness of platelets and coronary arteries from different species to synthetic thromboxane and prostaglandin endoperoxide analogues
1983
Inflammatory mediators and modulators of pain
2006
Effects of leukotriene E on pulmonary mechanics in the guinea pig.
1982
The Pharmacology of the Ductus Arteriosus
1998
Developmental Changes in Prostaglandin E2Receptor Subtypes in Porcine Ductus Arteriosus
1999
Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells.
1996
Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
2001
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Chapter 7. Modification of nociceptor responses by inflammatory mediators and second messengers implicated in their action – a study in canine testicular polymodal receptors
1996
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester
1996
Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear Targeting
1999 StandoutNobel
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP 2
1999
(15 R)‐16‐m‐Tolyl‐17,18,19,20‐tetranorisocarbacyclin: A Stable Ligand with High Binding Affinity and Selectivity for a Prostacyclin Receptor in the Central Nervous System
1996 StandoutNobel
PGE2 modulates the tetrodotoxin‐resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP‐protein kinase A cascade.
1996
Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor
1999
Possible Involvement of Cytoskeleton in Collagen-stimulated Activation of Phospholipases in Human Platelets
1989
Functional interaction of the carboxylic acid group of agonists and the arginine residue of the seventh transmembrane domain of prostaglandin E receptor EP3 subtype
1997
Dissociation of the contractile and hypertrophic effects of vasoconstrictor prostanoids in vascular smooth muscle.
1992
Works of Robert A. Coleman being referenced
Structures of three distinct activator–TFIID complexes
2009
Structural Changes in TAF4b-TFIID Correlate with Promoter Selectivity
2008
Sustained Activation of a G Protein-coupled Receptor via “Anchored” Agonist Binding
1996
A novel inhibitory prostanoid receptor in piglet saphenous vein
1994
Striatal and extrastriatal microPET imaging of D2/D3 dopamine receptors in rat brain with [18F]fallypride and [18F]desmethoxyfallypride
2011
Prostanoid‐induced contraction of human bronchial smooth muscle is mediated by TP‐receptors
1989
Salmeterol, a novel, long‐acting β2‐adrenoceptor agonist: characterization of pharmacological activityin vitroandin vivo
1991
PGI2-induced activation and sensitization of articular mechanonociceptors
1991
EP4 prostanoid receptor‐mediated vasodilatation of human middle cerebral arteries
2004
Dimerization of the TATA Binding Protein
1995
5‐HT2B receptors play a key role in mediating the excitatory effects of 5‐HT in human colon in vitro
2002
Dynamic interplay of TFIIA, TBP and TATA DNA
1997
Further evidence that tachykinin-induced contraction of human isolated bronchus is mediated only by NK2-receptors
1995
Evidence for Functional Binding and Stable Sliding of the TATA Binding Protein on Nonspecific DNA
1995
Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol
1994
Transcription initiation by human RNA polymerase II visualized at single-molecule resolution
2012 Nobel
Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils
1995
Prostanoid and leukotriene receptors: a progress report from the IUPHAR working parties on classification and nomenclature.
1995
The contractile action of slow reacting substance of anaphylaxis (SRS-A) on guinea-pig isolated lung strip [proceedings].
1979
CONTRACTILE AND RELAXANT ACTIONS OF PROSTAGLANDINS ON GUINEA‐PIG ISOLATED TRACHEA
1980
COMPARISON OF THE ACTIONS OF U‐46619, A PROSTAGLANDIN H2‐ANALOGUE, WITH THOSE OF PROSTAGLANDIN H2 AND THROMBOXANE A2 ON SOME ISOLATED SMOOTH MUSCLE PREPARATIONS
1981
Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus.
1994
Characterisation of the prostanoid receptors mediating contraction of guinea-pig isolated trachea
1985
Prostanoid receptors — the development of a working classification
1984
Exosites: their current status, and their relevance to the duration of action of long-acting β2-adrenoceptor agonists
1996
The pharmacology of salmeterol
1993
U-46619, a selective thromboxane A2-like agonist? [proceedings].
1980
Measurement of Cytochrome P450 Gene Induction in Human Hepatocytes using Quantitative Real-Time Reverse Transcriptase-Polymerase Chain Reaction
2000
International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.
1994 Standout
GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues
2005
Studies of the characterisation of prostanoid receptors: A proposed classification
1982
A NON‐ADRENERGIC INHIBITORY NERVOUS PATHWAY IN GUINEA‐PIG TRACHEA
1974
Comparison of the potencies of some prostaglandins as vasodilators in three vascular beds of the anaesthetised dog
1982