Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability
2011
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Attenuated Transforming Growth Factor β Signaling Promotes Nuclear Factor-κB Activation in Head and Neck Cancer
2009
Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer
2014
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
2013
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Estimation of Absolute Protein Quantities of Unlabeled Samples by Selected Reaction Monitoring Mass Spectrometry
2011
Glucose-dependent de Novo Lipogenesis in B Lymphocytes
2014
Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone
2015
Hallmarks of Cancer: The Next Generation
2011 Standout
Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor
2013
ErbB2 Activation Upregulates Glutaminase 1 Expression Which Promotes Breast Cancer Cell Proliferation
2013
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
EGFR Antagonists in Cancer Treatment
2008 Standout
Chemoprevention of squamous cell carcinoma of the head and neck
2007
The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo
2015
mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells
2016
MYC on the Path to Cancer
2012 Standout
Differential contribution of key metabolic substrates and cellular oxygen in HIF signalling
2014
Glutaminase activity determines cytotoxicity of l-asparaginases on most leukemia cell lines
2015
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress
2015
A guide to immunometabolism for immunologists
2016 Standout
Phage-Induced Expression of CRISPR-Associated Proteins Is Revealed by Shotgun Proteomics in Streptococcus thermophilus
2012
Glutamine and cancer: cell biology, physiology, and clinical opportunities
2013
Acetate Dependence of Tumors
2014
Targeting glutamine metabolism in myeloproliferative neoplasms
2015
Head and neck cancer
2008 Standout
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions
2012
Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact
2014
The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4
2013
When Checkpoints Fail
1997 StandoutNobel
Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation
2015
Development trends for human monoclonal antibody therapeutics
2010
Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
2014
The molecular biology of head and neck cancer
2010 Standout
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen
2007
Telomere Length and Telomerase Expression in Atypical Adenomatous Hyperplasia and Small Bronchioloalveolar Carcinoma of the Lung
2007
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Global cancer statistics
2011 Standout
Control of glutamine metabolism by the tumor suppressor Rb
2013
HPV-associated head and neck cancer: a virus-related cancer epidemic
2010 Standout
Characterization of G1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents.
1994
Increased expression of mutant forms of p53 oncogene in primary lung cancer
1990
Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
2015
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer
1997
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Refining the diagnosis of oropharyngeal squamous cell carcinoma using human papillomavirus testing
2010
Therapies Directed Against Epidermal Growth Factor Receptor in Aerodigestive Carcinomas
2007
Mass spectrometric protein maps for biomarker discovery and clinical research
2013
Increased UV‐induced SCEs but normal repair of DNA damage in p53‐deficient mouse cells
1994
Mitochondria in the Regulation of Innate and Adaptive Immunity
2015
ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation
2012
Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
2014
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Evolving 'omics' technologies for diagnostics of head and neck cancer
2008
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
2004
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Gene-expression profiles predict survival of patients with lung adenocarcinoma
2002 Standout
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Biological and clinical relevance of transcriptionally active human papillomavirus (HPV) infection in oropharynx squamous cell carcinoma
2009
Field-resolved infrared spectroscopy of biological systems
2020 StandoutNatureNobel
Reassessment of Exosome Composition
2019 Standout
Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
2015
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer
2008 Standout
Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development
2014
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
Hypoxic Regulation of Glutamine Metabolism through HIF1 and SIAH2 Supports Lipid Synthesis that Is Necessary for Tumor Growth
2014
Redox control of glutamine utilization in cancer
2014
Distinct Risk Factor Profiles for Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Cancers
2008 Standout
Effects of hypoxia and HIFs on cancer metabolism
2012
Revisiting biomarker discovery by plasma proteomics
2017
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
2014
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
p53 Mutations in Human Cancers
1991 StandoutScience
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
2012
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.
1995
Small GTP-Binding Proteins
2001 Standout
162 Differential sensitivity of P53+ and P53- cells to caffeine-induced radiosensitization and override of G2 delay
1995
Regulation of mammalian nucleotide metabolism and biosynthesis
2015
Impact of host cell line choice on glycan profile
2017
DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways.
1994
Protein Analysis by Shotgun/Bottom-up Proteomics
2013
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Online Nanoflow RP−RP-MS Reveals Dynamics of Multicomponent Ku Complex in Response to DNA Damage
2010
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.
1994
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.
1994 StandoutNobel
Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation
2015
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch
2016
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
2015
Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach
2015
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Paradoxical roles for lysyl oxidases in cancer—A prospect
2007
p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines.
1991
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.
1994
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment
2015
Testing the Role of p53 in the Expression of Genetic Instability and Apoptosis in Ataxia-telangiectasia
1994
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
A key role for transketolase-like 1 in tumor metabolic reprogramming
2016
Block in Anaphase Chromosome Separation Caused by a Telomerase Template Mutation
1997 StandoutScienceNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis.
2009
Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard.
1994 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells
2014
Works of Robbert J.C. Slebos being referenced
Gene Expression Profiles Identify Epithelial-to-Mesenchymal Transition and Activation of Nuclear Factor-κB Signaling as Characteristics of a High-risk Head and Neck Squamous Cell Carcinoma
2006
Gene Expression Differences Associated with Human Papillomavirus Status in Head and Neck Squamous Cell Carcinoma
2006
C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas.
1994
Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
2012
Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose
2008 Standout
Integrative Omics Analysis Reveals the Importance and Scope of Translational Repression in microRNA-mediated Regulation
2013
Methods for Peptide and Protein Quantitation by Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry
2011
p53 alterations in atypical alveolar hyperplasia of the human lung
1998
Cadmium is a mutagen that acts by inhibiting mismatch repair
2003
In-depth Proteomic Analysis of Nonsmall Cell Lung Cancer to Discover Molecular Targets and Candidate Biomarkers
2012
A Bioinformatics Workflow for Variant Peptide Detection in Shotgun Proteomics
2011
K‐ ras oncogene activation in lung adenocarcinomas from former smokers evidence that K‐ ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung
1993
TagRecon: High-Throughput Mutation Identification through Sequence Tagging
2010
Protein Identification Using Customized Protein Sequence Databases Derived from RNA-Seq Data
2011
Evaluation of Strong Cation Exchange versus Isoelectric Focusing of Peptides for Multidimensional Liquid Chromatography-Tandem Mass Spectrometry
2008
Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung.
1988
The frequency of p53, k-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma
2000
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage.
1993
Comparative Shotgun Proteomics Using Spectral Count Data and Quasi-Likelihood Modeling
2010
Depletion of Abundant Plasma Proteins and Limitations of Plasma Proteomics
2010
Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas
2006