Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Specificity of RNA–RNA helix recognition
2002 StandoutNobel
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline
2016
Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination
1997
Mechanisms of SARS-CoV-2 entry into cells
2021 Standout
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
1997 StandoutNature
AP-1 function and regulation
1997 Standout
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Regulation of transcription by MAP kinase cascades
1996
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
A Targeted DNA-PKcs-Null Mutation Reveals DNA-PK-Independent Functions for KU in V(D)J Recombination
1998
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Deciphering the splicing code
2010 Nature
Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
1995
Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
2004 StandoutNobel
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
1994 Standout
Inactivation of the HR6B Ubiquitin-Conjugating DNA Repair Enzyme in Mice Causes Male Sterility Associated with Chromatin Modification
1996
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Activation by locus control regions?
1999
Regulation and function of the JNK subgroup of MAP kinases
1997
Transcriptional regulation by hypoxia inducible factors
2013
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
1996 StandoutNature
The stress-activated protein kinase subfamily of c-Jun kinases
1994 StandoutNature
Ectopic Expression of Nonliganded Retinoic Acid Receptor β Abrogates AP-1 Activity by Selective Degradation of c-Jun in Cervical Carcinoma Cells
2004 StandoutNobel
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1994 StandoutNature
The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases
1995 Standout
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
2001 StandoutNature
Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase
2000 StandoutNobel
Nuclear import by karyopherin-βs: Recognition and inhibition
2010
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
Ceramide Activates the Stress-activated Protein Kinases
1995
c-Jun NH2-terminal Kinases Target the Ubiquitination of Their Associated Transcription Factors
1997
The Mammalian UV Response
2000
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Serotonin 5-HT1A Receptor-mediated Erk Activation Requires Calcium/Calmodulin-dependent Receptor Endocytosis
1999 StandoutNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells
1994 StandoutScience
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
2001 StandoutNature
A DNA Repair Complex Functions as an Oct4/Sox2 Coactivator in Embryonic Stem Cells
2011
Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase
1994 StandoutScience
Multifarious roles of sialic acids in immunity
2012
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
A murine ATFa-associated factor with transcriptional repressing activity
2000
Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis
2001
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo
1997
Angiotensin Blockade Inhibits Activation of Mitogen-Activated Protein Kinases in Rat Balloon-Injured Artery
1998 StandoutNobel
Glycosphingolipid degradation and animal models of GM2‐gangliosidoses
1998
Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade.
1996
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
1995 StandoutScience
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.
1995
Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia
1997 StandoutNobel
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.
1995
The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase.
1996
Integrin Signaling
1999 StandoutScience
Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway
1995 Science
Fos is an essential component of the mammalian UV response.
1995
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.
1993
Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain
2002
Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways
1997 StandoutScience
Activated MEK Stimulates Expression of AP-1 Components Independently of Phosphatidylinositol 3-Kinase (PI3-Kinase) but Requires a PI3-Kinase Signal To Stimulate DNA Synthesis
1999
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
ATF-2 contains a phosphorylation-dependent transcriptional activation domain.
1995
Regulation of c-jun Expression during Hypoxic and Low-Glucose Stress
1994
MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction Pathway
1996
THE UBIQUITIN SYSTEM
1998 StandoutNobel
G-protein-coupled Receptor (GPCR) Kinase Phosphorylation and β-Arrestin Recruitment Regulate the Constitutive Signaling Activity of the Human Cytomegalovirus US28 GPCR
2003 StandoutNobel
JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.
1994
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Works of Robbert J. Rottier being referenced
Hypoxia Inducible Factor 3α Plays a Critical Role in Alveolarization and Distal Epithelial Cell Differentiation during Mouse Lung Development
2013
A point mutation in the neu-1 locus causes the neuraminidase defect in the SM/J mouse
1998
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
2011
Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the β-globin locus control region in vivo
1998
Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells.
1995 StandoutNobel
SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site
2021
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors
2009
Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.
1993