Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
A Genetic Variant of Aurora Kinase A Promotes Genomic Instability Leading to Highly Malignant Skin Tumors
2009
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
2004 StandoutScience
Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer
2011
Downregulation of Plk1 Expression By Receptor-Mediated Uptake of Antisense Oligonucleotide-Loaded Nanoparticles
2008
PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Fluorescent Sensors of Protein Kinases
2012
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity
2000 StandoutNobel
Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase
2009 StandoutNobel
Transcriptional control by cell-cycle regulators: A review
1999
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Potentiation of Human Estrogen Receptor α Transcriptional Activation through Phosphorylation of Serines 104 and 106 by the Cyclin A-CDK2 Complex
1999
APC/CCdc20 Controls the Ubiquitin-Mediated Degradation of p21 in Prometaphase
2007
Cyclin D1 and breast cancer
2006
Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis
2006
DNA damage checkpoints in mammals
2005
Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor
1997
BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells
2006
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
Regulation of the G2/M transition by p53
2001 Standout
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Genetic instability in cancer cells by impaired cell cycle checkpoints
2006
Analyzing real-time PCR data by the comparative CT method
2008 Standout
A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA
1998
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage
2000
H2O2 Induces a Transient Multi-phase Cell Cycle Arrest in Mouse Fibroblasts through Modulating Cyclin D and p21Cip1 Expression
2002
A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
2009
Rescue of Cyclin D1 Deficiency by Knockin Cyclin E
1999
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Estrogen-Induced Retinoic Acid Receptor α1 Gene Expression: Role of Estrogen Receptor-Sp1 Complex
1998
Polo-like Kinase-1 Controls Recovery from a G2 DNA Damage-Induced Arrest in Mammalian Cells
2004
Checkpoint control and cancer
2011
p21 in cancer: intricate networks and multiple activities
2009 Standout
The emerging roles of forkhead box (Fox) proteins in cancer
2007
Krüppel-like Factor 4 Mediates p53-dependent G1/S Cell Cycle Arrest in Response to DNA Damage
2003
A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer
2003
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2
1998
Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia
2014
Selective Ablation of Retinoblastoma Protein Function by the RET Finger Protein
2005
Growth factor activation of the estrogen receptor in vascular cells occurs via a mitogen-activated protein kinase-independent pathway.
1998
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
2009
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
2000 Nature
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Cellular mechanisms of tumour suppression by the retinoblastoma gene
2008
Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities
2017
Initial testing of the aurora kinase a inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP)
2010
Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy
2003
Oncogenic functions of tumour suppressor p21Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts
2002
Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
2016
Origin and physiological roles of inflammation
2008 StandoutNature
Generation of a functional mammary gland from a single stem cell
2006 StandoutNature
Somatic cell type specific gene transfer reveals a tumor-promoting function for p21Waf1/Cip1
2007
Roles of aurora‐A kinase in mitotic entry and G2 checkpoint in mammalian cells
2002
NF-κB and cell-cycle regulation: the cyclin connection
2001
Think globally, act locally: the making of a mouse mammary gland
1998
Cyclin B2 and p53 control proper timing of centrosome separation
2014
Interactions of Nuclear Receptor Coactivator/Corepressor Proteins with the Aryl Hydrocarbon Receptor Complex
1999
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1
1998
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Alternative mammary oncogenic pathways are induced by D-type cyclins; MMTV-cyclin D3 transgenic mice develop squamous cell carcinoma
2003
Cyclins and cdks in development and cancer: a perspective
2005
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Cyclin A is a prognostic indicator in early stage breast cancer with and without tamoxifen treatment
2002
Cyclins and breast cancer
1998
Evolving Ideas about Cyclins
1999
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain
2003
Oncogenic PI3K deregulates transcription and translation
2005
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity
2009
Differential Control of Transcription by DNA-bound Cyclins
2001 StandoutNobel
Mechanisms for Initiating Cellular DNA Replication
2013
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Cyclin D1 expression in invasive breast cancer. Correlations and prognostic value.
1997
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb
1997
Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein
1998
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal
2002
The coregulator exchange in transcriptional functions of nuclear receptors
2000 Standout
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA
2002
Ligand-independent Activation of Steroid Receptors: New Roles for Old Players
1999
Mechanisms of Estrogen Action
2001 Standout
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
2008
Prophase Destruction of Emi1 by the SCFβTrCP/Slimb Ubiquitin Ligase Activates the Anaphase Promoting Complex to Allow Progression beyond Prometaphase
2003
Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex
1997
Cancer Genome Landscapes
2013 StandoutScience
Surviving the Breakup: The DNA Damage Checkpoint
2006
Transcriptional Activation of Insulin-Like Growth Factor-Binding Protein-4 by 17β-Estradiol in MCF-7 Cells: Role of Estrogen Receptor-Sp1 Complexes*
1999
Cyclin D1 Stimulation of Estrogen Receptor Transcriptional Activity Independent of cdk4†
1997
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
p21WAF1/CIP1 Selectively Controls the Transcriptional Activity of Estrogen Receptor α
2005
Toward Maintaining the Genome: DNA Damage and Replication Checkpoints
2002
Use and Abuse of RNAi to Study Mammalian Gene Function
2012 StandoutScienceNobel
A System for Stable Expression of Short Interfering RNAs in Mammalian Cells
2002 StandoutScience
Estrogen-Induced c-fos Protooncogene Expression in MCF-7 Human Breast Cancer Cells: Role of Estrogen Receptor Sp1 Complex Formation*
1998
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
A 1.3-Å resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation
1998 StandoutNobel
Transcriptional Activation of c-fos Protooncogene by 17β-Estradiol: Mechanism of Aryl Hydrocarbon Receptor-Mediated Inhibition
1999
Nonnuclear Actions of Estrogen
2002
P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor
1999
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse
1999 StandoutScience
Dynamic FoxO transcription factors
2007
Works of Rob Klompmaker being referenced
p21 Inhibits Thr161 Phosphorylation of Cdc2 to Enforce the G2 DNA Damage Checkpoint
2000
A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer
1996
CDK-Independent Activation of Estrogen Receptor by Cyclin D1
1997
p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases
1998
Inhibition of Polo-like Kinase-1 by DNA Damage Occurs in an ATM- or ATR-dependent Fashion
2001
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
2008 Nature
Polo-like kinase-1 is a target of the DNA damage checkpoint
2000
Ablation of the spindle assembly checkpoint by a compound targeting Mps1
2005
Cell Cycle Inhibition by FoxO Forkhead Transcription Factors Involves Downregulation of Cyclin D
2002
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing
2009
Cyclin D1 Triggers Autonomous Growth of Breast Cancer Cells by Governing Cell Cycle Exit
1996