Citation Impact
Citing Papers
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
2006 StandoutScience
Minocycline Down-regulates MHC II Expression in Microglia and Macrophages through Inhibition of IRF-1 and Protein Kinase C (PKC)α/βII
2007
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
2006 Standout
Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotective mechanisms
2006
Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908)
1999
The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties
2010
Interleukin-17 family and IL-17 receptors
2003
Tetracyclines inhibit activated B cell function
2001
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases
2009
Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model
2009
Antigen-Specific T Cell Sensitization Is Impaired in IL-17-Deficient Mice, Causing Suppression of Allergic Cellular and Humoral Responses
2002
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
2008
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
2005 Standout
Minocycline Treatment Reduces Delayed Oligodendrocyte Death, Attenuates Axonal Dieback, and Improves Functional Outcome after Spinal Cord Injury
2004
Tetracycline prevents cancellous bone loss and maintains near-normal rates of bone formation in streptozotocin diabetic rats
1997
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Juvenile idiopathic arthritis
2007 Standout
Abdominal aortic aneurysm
2005 Standout
Post-injury administration of minocycline: An effective treatment for nerve-injury induced neuropathic pain
2011
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy
2003
Treatment of Osteoarthritis With Celecoxib, a Cyclooxygenase-2 Inhibitor: A Randomized Controlled Trial
1999
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
2008 StandoutNature
Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy
1999
Cytokines in asthma
1999
Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
2003 Standout
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
Osteoarthritis
2015 Standout
Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2
1999
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Pharmacologic suppression of experimental abdominal aortic aneurysms: A comparison of doxycycline and four chemically modified tetracyclines
1998
Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
2006
Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)
2001
Clinical potential of minocycline for neurodegenerative disorders
2004
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis
2000 Standout
Crohn's disease
2016 Standout
RECOMBINANT GLUCOCORTICOID INDUCED TUMOUR NECROSIS FACTOR RECEPTOR (rGITR) INDUCED COX-2 ACTIVITY IN MURINE MACROPHAGE Raw 264.7 CELLS
2002
The structure and proteolytic processing of Cbln1 complexes
2005
Tetracycline-mediated IgE isotype-specific suppression of ongoing human and murine IgE responses in vivo and murine memory IgE responses induced in vitro
2010
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
2001
Asthma
2001 Standout
Minocycline Slows Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis
2002
Minocycline inhibits LPS-induced retinal microglia activation
2005
Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat
2008
Tetracyclines: Nonantibiotic properties and their clinical implications
2006
Update of ACR Guidelines for Osteoarthritis
2002
Interleukin‐17 in rheumatoid arthritis: If T cells were to contribute to inflammation and destruction through synergy
2003
Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice
2003
Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease
2002
The immune contexture in human tumours: impact on clinical outcome
2012 Standout
Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17
2003 Standout
Minocycline: A neuroprotective agent for hypoxic‐ischemic brain injury in the neonate?
2008
Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain
2007
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
2016
Rise and fall of minocycline in neuroprotection: need to promote publication of negative results
2004
Treatment of early seropositive rheumatoid arthritis: Doxycycline plus methotrexate versus methotrexate alone
2006
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
1999
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood–brain barrier, and damage in the nigral dopaminergic system
2004
Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease
2004
Sarcoidosis
2007 Standout
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
2008
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
A novel action of minocycline: Inhibition of human immunodeficiency virus type 1 infection in microglia
2004
COX-2 inhibitors
1999 Standout
The promise of minocycline in neurology
2004
TNF‐α converting enzyme (TACE) is inhibited by TIMP‐3
1998
Minocycline enhances MPTP toxicity to dopaminergic neurons
2003
Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases
2005 Standout
Matrix Metalloproteinases
1999 Standout
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
Minocycline decreases in vitro microglial motility, β1‐integrin, and Kv1.3 channel expression
2007
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Enhancing Effect of IL-17 on IL-1-Induced IL-6 and Leukemia Inhibitory Factor Production by Rheumatoid Arthritis Synoviocytes and Its Regulation by Th2 Cytokines
1998
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
1998
The Effect of Minocycline on Motor Neuron Recovery and Neuropathic Pain in a Rat Model of Spinal Cord Injury
2011
Part II: Beneficial Effects of the Peroxynitrite Decomposition Catalyst FP15 in Murine Models of Arthritis and Colitis
2002
Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease
2002
Minocycline treatment for HIV-associated cognitive impairment
2011
Tetracyclines Modulate Protease-Activated Receptor 2-Mediated Proinflammatory Reactions in Epidermal Keratinocytes
2009
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
2005 Standout
Minocycline treatment in acute stroke
2007
Diagnosis and Treatment of Hip and Knee Osteoarthritis
2021 Standout
Minocycline, a Tetracycline Derivative, Is Neuroprotective against Excitotoxicity by Inhibiting Activation and Proliferation of Microglia
2001
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
1999
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Functional Expression of a Fungal Laccase in Saccharomyces cerevisiae by Directed Evolution
2003 StandoutNobel
Simultaneous LFA-1 and CD40 Ligand Antagonism Prevents Airway Remodeling in Orthotopic Airway Transplantation: Implications for the Role of Respiratory Epithelium as a Modulator of Fibrosis
2005
Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.
1999
Microbial Lipopeptides Induce the Production of IL-17 in Th Cells
2000
Interleukin-17 inhibits tumor cell growth by means of a T-cell–dependent mechanism
2002
Minocycline: far beyond an antibiotic
2013 Standout
Association of CD4+CD25+T Cells with Prevention of Severe Destructive Arthritis inBorrelia burgdorferi-Vaccinated and Challenged Gamma Interferon-Deficient Mice Treated with Anti-Interleukin-17 Antibody
2004
Knee osteoarthritis has doubled in prevalence since the mid-20th century
2017 Standout
Laccases: A Useful Group of Oxidoreductive Enzymes
1999
CD4 + T-cell subsets in inflammatory diseases: beyond the T h 1/T h 2 paradigm
2016
IL-17: prototype member of an emerging cytokine family
2002
Green and Sustainable Solvents in Chemical Processes
2018 Standout
Macrophage activation syndrome
2002
Should tetracycline treatment be used more extensively for rheumatoid arthritis? Metaanalysis demonstrates clinical benefit with reduction in disease activity.
2003
High Levels of IL-17 in Rheumatoid Arthritis Patients: IL-15 Triggers In Vitro IL-17 Production Via Cyclosporin A-Sensitive Mechanism
2000
Cyclooxygenase in biology and disease
1998 Standout
Ischemic Cell Death in Brain Neurons
1999 Standout
Rapamycin, proliferation and geroconversion to senescence
2018
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Effect of Alcohol Consumption on Host Release of Interleukin‐17 During Pulmonary Infection With Klebsiella pneumoniae
2001
GITR Activation Induces an Opposite Effect on Alloreactive CD4+ and CD8+ T Cells in Graft-Versus-Host Disease
2004 StandoutNobel
Minocycline Reduces Traumatic Brain Injury-mediated Caspase-1 Activation, Tissue Damage, and Neurological Dysfunction
2001
Supercritical fluid extraction and fractionation of natural matter
2006 Standout
Interleukin‐17: the missing link between T‐cell accumulation and effector cell actions in rheumatoid arthritis?
2004
Osteoarthritis: an update with relevance for clinical practice
2011 Standout
Minocycline as a Neuroprotective Agent
2005
Physiology of Microglia
2011 Standout
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
1999
T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis
2007 StandoutNobel
Works of R.N. Patel being referenced
Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.
1997
Interleukin‐17 up‐regulation of nitric oxide production in human osteoarthritis cartilage
1997
Post‐transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines
1997
Differential anti-inflammatory effects of immunosuppressive drugs: Cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production
2000
Extraction of cashew (Anacardium occidentale) nut shell liquid using supercritical carbon dioxide
2005
Regulation of Cytosolic COX-2 and Prostaglandin E2 Production by Nitric Oxide in Activated Murine Macrophages
1999
TNF-α Convertase Enzyme from Human Arthritis-Affected Cartilage: Isolation of cDNA by Differential Display, Expression of the Active Enzyme, and Regulation of TNF-α
1998
Potential use of a white-rot fungus Antrodiella sp. RK1 for biopulping
1994
Tetracycline Up-Regulates COX-2 Expression and Prostaglandin E2 Production Independent of Its Effect on Nitric Oxide
1999
A Novel Mechanism of Action of Chemically Modified Tetracyclines: Inhibition of COX-2-Mediated Prostaglandin E2 Production
1999
A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases
1996
TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha.
1998
Autocrine production of IL-1 beta by human osteoarthritis-affected cartilage and differential regulation of endogenous nitric oxide, IL-6, prostaglandin E2, and IL-8.
1998