Citation Impact
Citing Papers
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Expression Cloning and Pharmacological Characterization of a Human Hippocampal Neuropeptide Y/Peptide YY Y2 Receptor Subtype
1995
Acetylation of Stat1 modulates NF-κB activity
2006
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Synergistic induction of apoptosis and chemosensitization of human colorectal cancer cells by histone deacetylase inhibitor, scriptaid, and proteasome inhibitors: potential mechanisms of action
2012
EXPRESSION OF CONCERN: Antitumor effects of a novel sulfur‐containing hydroxamate histone deacetylase inhibitor H40
2008
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
2007 StandoutNobel
Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy
2003
Regulation of cell death and autophagy by IKK and NF‐κB: critical mechanisms in immune function and cancer
2012
Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
2005
The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer
2003
NF-κB: arresting a major culprit in cancer
2002
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
Molecular mechanisms of drug resistance
2005
NF-κB in cancer: from innocent bystander to major culprit
2002 Standout
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Shared Principles in NF-κB Signaling
2008 Standout
Smoldering and polarized inflammation in the initiation and promotion of malignant disease
2005 Standout
Cancer drug resistance: an evolving paradigm
2013 Standout
Adenosine receptors as therapeutic targets
2006 Standout
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
2004 Standout
Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib
2003
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
SMRT Derepression by the IκB Kinase α
2004
Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks
2004 Nobel
Human acute myeloid leukemia stem cells
2003
The complexity of NF-κB signaling in inflammation and cancer
2013 Standout
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Cancer genes and the pathways they control
2004 Standout
Valproic Acid Inhibits Angiogenesis in Vitro and in Vivo
2004
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
2005 Standout
Interplay between protein synthesis and degradation in the CNS: physiological and pathological implications
2006
Adenosine and sleep–wake regulation
2004
Cellular processing of platinum anticancer drugs
2005 Standout
NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target
2010
Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity
2002
Photodynamic therapy and anti-tumour immunity
2006 Standout
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Adenosine-mediated cardioprotection in the aging myocardium
2004
Modulation of A1 adenosine receptor signaling by peroxynitrite
2003
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
2017 Standout
The role of G protein-coupled receptors in the pathology of Alzheimer's disease
2011
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
2008 Standout
Distribution, biochemistry and function of striatal adenosine A2A receptors
1999
Fine-tuning modulation of myenteric motoneurons by endogenous adenosine: On the role of secreted adenosine deaminase
2006
Long-Term Potentiation Is Impaired in Middle-Aged Rats: Regional Specificity and Reversal by Adenosine Receptor Antagonists
2005
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
What We Talk About When We Talk About Fat
2014 Standout
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Nuclear factor-κB is upregulated in colorectal cancer
2001
Self-projection and the brain
2006 Standout
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
2004 Standout
Cancer-related inflammation and treatment effectiveness
2014 Standout
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Spermidine/Spermine N1-Acetyltransferase 2 (SSAT2) functions as a coactivator for NF-κB and cooperates with CBP and P/CAF to enhance NF-κB-dependent transcription
2006
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
Presynaptic modulation of cholinergic and non‐cholinergic fast synaptic transmission in the myenteric plexus of guinea pig ileum
2004
Activation of A3 Adenosine Receptor Provides Lung Protection Against Ischemia-Reperfusion Injury Associated with Reduction in Apoptosis
2004
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Dual effects of adenosine on acetylcholine release from myenteric motoneurons are mediated by junctional facilitatory A2A and extrajunctional inhibitory A1 receptors
2004
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
ATP Inhibits Glutamate Synaptic Release by Acting at P2Y Receptors in Pyramidal Neurons of Hippocampal Slices
2000
The Role and Regulation of Adenosine in the Central Nervous System
2001 Standout
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Receptors for Purines and Pyrimidines
1998 Standout
IκB Kinase α-Mediated Derepression of SMRT Potentiates Acetylation of RelA/p65 by p300
2005
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
Synthesis of Sulfonamides and Evaluation of Their Histone Deacetylase (HDAC) Activity
2007
Levels of Endogenous Adenosine in Rat Striatum. I. Regulation by Ionotropic Glutamate Receptors, Nitric Oxide and Free Radicals
1998
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
2007 Standout
Control of Sleep and Wakefulness
2012
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Inhibition of anchorage-independent growth and lung metastasis of A549 lung carcinoma cells by IκBβ
2001
Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
1999 Standout
Cellular cross-talk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease
2012
About Sleep's Role in Memory
2013 Standout
Cardiovascular Effects of Nitric Oxide and Adenosine in the Nucleus Tractus Solitarii of Rats
1998
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release
1996
The cardenolide UNBS1450 is able to deactivate nuclear factor κB–mediated cytoprotective effects in human non–small cell lung cancer cells
2006
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
Blockade of Histone Deacetylase Inhibitor-Induced RelA/p65 Acetylation and NF-κB Activation Potentiates Apoptosis in Leukemia Cells through a Process Mediated by Oxidative Damage, XIAP Downregulation, and c-Jun N-Terminal Kinase 1 Activation
2005
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Adenosine A2receptor‐mediated excitation of a subset of AH/Type 2 neurons and elevation of cAMP levels in myenteric ganglia of guinea‐pig ileum
1994
NF-κB in cancer—a friend turned foe
2004
Physiology of Microglia
2011 Standout
CLINICAL DEVELOPMENT OF HISTONE DEACETYLASE INHIBITORS AS ANTICANCER AGENTS
2004
Works of R.Michael Broad being referenced
Ineffectiveness of Histone Deacetylase Inhibitors to Induce Apoptosis Involves the Transcriptional Activation of NF-κB through the Akt Pathway
2003
Nitric oxide interacts with oxygen free radicals to evoke the release of adenosine and adenine nucleotides from rat hippocampal slices
2000
Inhibition of nuclear factor κB chemosensitizes non–small cell lung cancer through cytochrome c release and caspase activation
2002
Release of Adenosine from Rat Hippocampal Slices by Nitric Oxide Donors
1996
Inhibition of NF-κB sensitizes non–small cell lung cancer cells to chemotherapy-induced apoptosis
2000
Combined proteasome and histone deacetylase inhibition in non–small cell lung cancer
2004
Adenosine and 5-HT inhibit substance P release from nerve endings in myenteric ganglia by distinct mechanisms
1993
Adenosine A1 receptors mediate inhibition of tachykinin release from perifused enteric nerve endings
1992
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
1996
A1 adenosine receptor overexpression attenuates ischemia-reperfusion-induced apoptosis and caspase 3 activity
2003
PYY: a neuropeptide in the canine enteric nervous system
1993